Disruption of redox homeostasis in cerebral cortex of developing rats by acylcarnitines accumulating in medium-chain acyl-CoA dehydrogenase deficiency

International Journal of Developmental Neuroscience

Volumn 30, Issue 5, 2012, Pages 383-390

  Tonin, Anelise M ^a   Grings, Mateus ^a   Knebel, Lisiane A ^a   Zanatta, Ângela ^a   Moura, Alana P ^a   Ribeiro, César A J ^a   Leipnitz, Guilhian ^a   Wajner, Moacir ^a,b  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

Author keywords

Acylcarnitines; Antioxidant defenses; Lipid oxidative damage; MCAD deficiency; Protein oxidative damage; Rat brain

Indexed keywords

4 DECENOYLCARNITINE; ACYLCARNITINE; ALPHA TOCOPHEROL; CARBONYL DERIVATIVE; CARNITINE; DECANOYLCARNITINE; GLUTATHIONE; HEXANOYLCARNITINE; MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE; MELATONIN; OCTANOYLCARNITINE; SCAVENGER; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THIOL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; BRAIN CORTEX; CONCENTRATION (PARAMETERS); CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; IN VITRO STUDY; LIPID PEROXIDATION; MALE; MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE DEFICIENCY; NEUROLOGICAL COMPLICATION; NEUROPATHOLOGY; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CARBONYLATION; RAT;

ACYL-COA DEHYDROGENASE; ALPHA-TOCOPHEROL; ANIMALS; CARNITINE; CEREBRAL CORTEX; GLUTATHIONE; HOMEOSTASIS; LIPID METABOLISM, INBORN ERRORS; LIPID PEROXIDATION; MALE; MELATONIN; OXIDATIVE STRESS; PROTEIN CARBONYLATION; RATS; RATS, WISTAR; STATISTICS, NONPARAMETRIC; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

RATTUS;

EID: 84862181711     PISSN: 07365748     EISSN: 1873474X     Source Type: Journal    
DOI: 10.1016/j.ijdevneu.2012.03.238     Document Type: Article

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