Early Changes in Oxidative Stress Markers in a Rat Model of Acute Stress: Effect of l-carnitine on the Striatum

Basic and Clinical Pharmacology and Toxicology

Volumn 109, Issue 2, 2011, Pages 123-129

  Méndez Cuesta, Luis A ^a   Márquez Valadez, Berenice ^a   Pérez De la Cruz, Verónica ^a   Maldonado, Perla D ^a   Santana, Ricardo A ^a   Escobar Briones, Carolina ^b   Galván Arzate, Sonia ^a   Carrillo Mora, Paul ^a   Santamaría, Abel ^a  

^a NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

CARNITINE; CORTICOSTERONE; GLUTATHIONE; MANGANESE SUPEROXIDE DISMUTASE; SUPEROXIDE DISMUTASE;

ACUTE STRESS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; CORTICOSTERONE BLOOD LEVEL; DRUG EFFECT; IMMOBILIZATION STRESS; LIPID PEROXIDATION; MALE; MITOCHONDRIAL DYSFUNCTION; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE;

ACUTE DISEASE; ANIMALS; CARNITINE; CORPUS STRIATUM; CORTICOSTERONE; LIPID PEROXIDATION; MALE; MITOCHONDRIA; OXIDATIVE STRESS; RATS; RATS, WISTAR; RESTRAINT, PHYSICAL; STRESS, PSYCHOLOGICAL; SUPEROXIDE DISMUTASE;

ANIMALIA; RATTUS;

EID: 79960266509     PISSN: 17427835     EISSN: 17427843     Source Type: Journal    
DOI: 10.1111/j.1742-7843.2011.00691.x     Document Type: Article

References (51)

1. Selye H. A syndrome produced by diverse nocuous agents. Nature 1936;138:32.
2. Esch T, Stefano GB, Fricchione GL, Benson H. The role of stress in neurodegenerative diseases and mental disorders. Neuroendocrinol Lett 2002;23:199-208.
3. Swaab DF, Bao AM, Lucassen PJ. The stress system in the human brain in depression and neurodegeneration. Ageing Res Rev 2005;4:141-94.
4. Bao AM, Meynen G, Swaab DF. The stress system in depression and neurodegeneration: focus on the human hypothalamus. Brain Res Rev 2008;57:531-53.
5. Bandelow B, Zohar J, Hollander E, Kasper S, Moller HJ. World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the pharmacological treatment of anxiety, obsessive-compulsive and post-traumatic stress disorders. World J Biol Psychiatry 2001;3:171-99.
6. Bijl RV, Ravelli A, van Zessen G. Prevalence of psychiatric disorder in the general population: results of the Netherlands Mental Health Survey and Incidence Study (NEMESIS). Soc Psychiatry Psychiatr Epidemiol 1998;33:587-95.
7. Turner RJ, Lloyd DA. Stress burden and the lifetime incidence of psychiatric disorder in young adults. Arch Gen Psychiatry 2004;61:481-8.
8. McEwen BS. The neurobiology of stress: from serendipity to clinical relevance. Brain Res 2000;886:172-89.
9. Pardon MC. Stress and ageing interactions: a paradox in the context of shared etiological and physiopathological processes. Brain Res Rev 2007;54:251-73.
10. Lanfumey L, Mongeau R, Cohen-Salmon C, Hamon M. Corticosteroid-serotonin interactions in the neurobiological mechanisms of stress-related disorders. Neurosci Biobehav Rev 2008;32:1174-84.
11. Buynitsky T, Mostofsky DI. Restraint stress in biobehavioral research: recent developments. Neurosci Biobehav Rev 2009;33:1089-98.
12. Glavin GB, Paré WP, Sandbak T, Bakke H, Murison R. Restraint stress in biomedical research: an update. Neurosci Biobehav Rev 1994;18:223-49.
13. Liu J, Wang X, Mori A. Immobilization stress-induced antioxidant defense changes in rat plasma: effect of treatment with reduced glutathione. Int J Biochem 1994;26:511-7.
14. Liu J, Wang X, Shigenaga MK, Yeo HC, Mori A, Ames B. Immobilization stress causes oxidative damage to lipid, protein, and DNA in the brain of rats. FASEB J 1996;10:1532-8.
15. Şahin E, Gümüşlü S. Immobilization stress in rat tissues: alterations in protein oxidation, lipid peroxidation and antioxidant defenses system. Comp Biochem Physiol C Toxicol Pharmacol 2007;144:342-7.
16. Sayre LM, Perry G, Smith MA. Oxidative stress and neurotoxicity. Chem Res Toxicol 2008;21:172-88.
17. Zaidi SMKR, Banu Antioxidant potential of vitamins A, E and C in modulating oxidative stress in rat brain. Clin Chim Acta 2004;340:229-33.
18. Madrigal JLM, Moro MA, Lizasoain I, Lorenzo P, Fernández AP, Rodrigo J et al. Induction of cyclooxygenase-2 account of restraint stress-induced oxidative status in rat brain. Neuropsychopharmacology 2001;24:420-9.
19. Madrigal JLM, García-Bueno B, Moro MA, Lizasoain I, Lorenzo P, Leza JC. Relationship between cyclooxygenase-2 and nitric oxide synthase-2 in rat cortex after stress. Eur J Neurosci 2003;18:1701-5.
20. Radak Z, Sasvari M, Nyakas C, Kaneko T, Tahara S, Ohno H et al. Single bout of exercise eliminates the immobilization-induced oxidative stress in rats. Neurochem Int 2001;39:33-8.
21. Atif F, Yousuf S, Agarwal SK. Restraint stress-induced oxidative damage and its amelioration with selenium. Eur J Pharmacol 2008;600:59-63.
22. Floyd RA. Antioxidants, oxidative stress and degenerative neurological disorders. Proc Soc Exp Biol Med 1999;222:236-45.
23. Savitha S, Tamilselvan J, Anusuyadevi M, Panneerselvam C. Oxidative stress on mitochondrial antioxidant defense system in the aging process: role of DL-alpha-lipoic acid and l-carnitine. Clin Chim Acta 2005;355:173-80.
24. Jones LL, McDonald DA, Borum PG. Acylcarnitines: role in brain. Prog Lipid Res 2010;49:61-75.
25. Gülçin I. Antioxidant and antiradical activities of l-carnitine. Life Sci 2006;78:803-11.
26. Virmani A, Binienda Z. Role of carnitine esters in brain neuropathology. Mol Aspects Med 2004;25:533-49.
27. Hagen TM, Moreau R, Suh JH, Visioli F. Mitochondrial decay in the aging rat heart evidence for improvement by dietary supplementation of acetyl- l-carnitine and/or lipoic acid. Ann N Y Acad Sci 2002;85:214-23.
28. Kumaran S, Savitha S, Anusuya M, Panneerselvam C. l-carnitine and DL-α-lipoic acid reverse the age-related deficit in glutathione redox state in skeletal muscle and heart tissues. Mech Ageing Dev 2004;125:507-12.
29. Mansour HH. Protective role of carnitine ester against radiation-induced oxidative stress in rats. Pharmacol Res 2006;54:165-71.
30. Anusuya M, Kokilavani V, Murali G, Panneerselvam C. Oxidative stress-mediated macromolecular damage and dwindle in antioxidant status in aged rat brain regions: role of l-carnitine and DL-α-lipoic acid. Clin Chim Acta 2006;368:84-92.
31. Long J, Gao F, Tong L, Cotman CW, Ames BN, Liu J. Mitochondrial decay in the brains of old rats: ameliorating effect of alpha-lipoic acid and acetyl-l-carnitine. Neurochem Res 2009;34:755-63.
32. Santamaría A, Salvatierra-Sánchez R, Vázquez-Román B, Santiago-López D, Villeda-Hernández J, Galván-Arzate S et al. Protective effects of the antioxidant selenium on quinolinic acid-induced neurotoxicity in rats: in vivo and in vitro studies. J Neurochem 2003;86:479-88.
33. Silva-Adaya D, Pérez-De La Cruz V, Herrera-Mundo MN, Mendoza-Macedo K, Villeda-Hernandez J, Binienda Z et al. Excitotoxic damage, disrupted energy metabolism, and oxidative stress in the rat brain: antioxidant and neuroprotective effects of l-carnitine. J Neurochem 2008;105:677-89.
34. Santamaría D, Espinoza-González V, Ríos C, Santamaría A. Nω-Nitro-L-arginine, a nitric synthase inhibitor, antagonizes quinolinic acid-induced neurotoxicity and oxidative stress in rat striatal slices. Neurochem Res 1999;24:843-9.
35. Pérez-De La Cruz V, Gozález-Cortés C, Pedraza-Chaverrí J, Maldonado PD, Andrés-Martínez L, Santamaría A. Protective effect of S-allylcysteine on 3-nitropropionic acid-induced lipid peroxidation and mitochondrial dysfunction in rat brain synaptosomes. Brain Res Bull 2006;68:379-83.
36. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-7.
37. Berridge MV, Tan AS. Characterization of the cellular reduction of 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT): subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction. Arch Biochem Biophys 1993;303:474-82.
38. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983;65:55-63.
39. Pedraza-Chaverrí J, Maldonado PD, Medina-Campos ON, Olivares-Corichi IM, Granados-Silvestre MA, Hernández-Pando R et al. Garlic ameliorates gentamicin nephrotoxicity: relation to antioxidant enzymes. Free Radic Biol Med 2000;29:602-11.
40. Hissin PJ, Hilf R. A fluorometric method for determination of oxidized and reduced glutathione in tissues. Anal Biochem 1976;74:214-26.
41. Galván-Arzate S, Pedraza-Chaverrí J, Medina-Campos ON, Maldonado PD, Vázquez-Román B, Ríos C et al. Delayed effects of thallium in the rat brain: regional changes in lipid peroxidation and behavioral markers, but moderate alterations in antioxidants, after a single administration. Food Chem Toxicol 2005;43:1037-45.
42. Zaidi SMKR, Al-Qirim TM, Hoda N, Banu N. Modulation of restraint stress induced oxidative changes in rats by antioxidant vitamins. J Nutr Biochem 2003;14:633-6.
43. Filipović D, Pajović SB. Differential regulation of CuZnSOD expression in rat brain by acute and/or chronic stress. Cell Mol Neurobiol 2009;29:673-81.
44. Lowy MT, Wittenberg L, Yamamoto BK. Effect of acute stress on hippocampal glutamate levels and spectrin proteolysis in young and aged rats. J Neurochem 1995;65:268-74.
45. Psarra AG, Sekeris CE. Glucocorticoid receptors and other nuclear transcription factors in mitochondria and possible functions. Biochim Biophys Acta 2009;1787:431-6.
46. Arockia-Rani J, Panneerselvam C. Effect of l-carnitine on brain lipid peroxidation and antioxidant enzymes in old rats. J Gerontol A Biol Sci Med Sci 2002;57:B134-7.
47. de Vries HE, Witte M, Hondius D, Rozemuller AJM, Drukarch B, Hoozemans J et al. Nrf2-induced antioxidant protection: a promising target to counteract ROS-mediated damage in neurodegenerative disease? Free Radic Biol Med 2008;45:1375-83.
48. Kumar A, Goyal R, Prakash A. Possible GABAergic mechanism in the protective effect of allopregnenolone against immobilization stress. Eur J Pharmacol 2009;602:343-7.
49. Singh A, Kumar A. Protective effect of alprazolam against sleep deprivation-induced behavior alterations and oxidative damage in mice. Neurosci Res 2008;60:372-9.
50. Djordjevic J, Cvijic G, Davidovic V. Different activation of ACTH and corticosterone release in response to various stressors in rats. Physiol Res 2003;52:67-72.
51. Augustyniak A, Skrzydlewska E. The influence of l-carnitine supplementation on the antioxidative abilities of serum and the central nervous system of ethanol-induced rats. Metab Brain Dis 2010;25:381-9.