Enhanced Cdk5 activity and p35 translocation in the ventral striatum of acute and chronic methamphetamine-treated rats

Neuropsychopharmacology

Volumn 30, Issue 3, 2005, Pages 538-549

  Chen, Pei Chun ^a   Chen, Jin Chung ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Behavioral sensitization; Cdk5; Methamphetamine; p35; Roscovitine; Ventral striatum

Indexed keywords

COCAINE; CYCLIN DEPENDENT KINASE 5; METHAMPHETAMINE; PHOSPHOPROTEIN DARPP 32; PROTEIN P35; ROSCOVITINE; THREONINE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC TRANSMISSION; ENZYME ACTIVITY; LOCOMOTION; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; CORPUS STRIATUM; DOPAMINE AND CAMP-REGULATED PHOSPHOPROTEIN 32; DRUG ADMINISTRATION SCHEDULE; KETAMINE; MALE; METHAMPHETAMINE; NERVE TISSUE PROTEINS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN TRANSPORT; RATS; RATS, SPRAGUE-DAWLEY; STEREOTAXIC TECHNIQUES;

EID: 13944249205     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1300604     Document Type: Article

References (39)

1. Amitabh G, Tsai LH (2001). A kinase to dampen the effects of cocaine? Science 292: 236-239.
2. Bibb JA, Chen JS, Taylor JR, Svenningsson P, Nishi A, Snyder GL et al (2001). Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5. Nature 410: 376-380.
3. Bibb JA, Synder GL, Nishi A, Yan Z, Meijer L, Fienberg AA et al (1999). Phosphorylation of DARPP-32 by cdk5 modulates dopamine signaling in neurons. Nature 402: 669-671.
4. Cador M, Bjijou Y, Stinus L (1995). Evidence of a complete independence of the neurobiological substrates for the induction and expression of behavioral sensitization to amphetamine. Neuroscience 65: 385-389.
5. Cador M, Bjijou Y, Stinus L (1999). d-Amphetamine-induced behavioral sensitization: implication of a glutamatergic medial prefrontal cortex-ventral tegmental area innervation. Neuroscience 94: 705-711.
6. 3 receptor down-regulation and functional desensitization in the olfactory tubercle of amphetamine-sensitized rats. Brain Res 972: 159-167.
7. Dhavan R, Tsai LH (2001). A decade of CDK5. Nat Rev 2: 749-759.
8. Ferrer-Alcon M, Harpe RL, Guimon J, Garcia-Sevilla JA (2003). Downregulation of neuroal cdk5/p35 in opioid addicts and opiate-treated rats: relation to neurofilament phosphorylation. Neuropsychopharmacology 28: 947-955.
9. Grant P, Sharma P, Pant HC (2001). Cyclin-dependent protein kinase 5 (CDK5) and the regulation of neurofilament metabolism. Eur J Biochem 268: 1534-1546.
10. Greengard P (2001). The neurobiology of slow synaptic transmission. Science 294: 1024-1030.
11. Greengard P, Allen P, Nairn AC (1999). Beyond the dopamine receptor: the DARPP-32/protein phosphatase-1 cascade. Neuron 23: 435-437.
12. Groenewegen HJ, Mulder AB, Beijer AVJ, Wright CI, Lopes da Silva FH, Pennartz CMA (1999). Hippocampal and amygdaloid interactions in the nucleus accumbens. Psychobiology 27: 149-164.
13. Gupta A, Tsai LH (2001). A kinase to dampen the effects of cocaine. Science 292: 236-239.
14. Hsieh HC, Li HY, Lin MY, Chiou HY, Lin SY, Wong CH et al (2002). Differential expression of haloperidol-induced immediate early genes and CREB/pCREB binding in the nucleus accumbens of amphetamine-sensitized rats. Synapse 45: 230-244.
15. Kalivas PW, Stewart J (1991). Dopamine transmission in the initiation and expression of drug- and stress-induced sensitization of motor activity. Brain Res Rev 16: 223-244.
16. Keiz M, Chen J, Carlezon WA, Whisler K, Gilden L, Beckmann AM et al (1999). Expression of the transcription factor ΔFosB in the brain controls sensitivity to cocaine. Nature 401: 272-275.
17. Koob GF (1996). Drug addiction: the yin and yang of hedonic homeostasis. Neuron 16: 893-896.
18. Kuczenski R, Segal DS (1999). Sensitization of amphetamine-induced stereotyped behaviors during the acute response. J Pharmacol Exp Ther 288: 699-709.
19. Lew J (1994). Neuronal cdc2-like kinase is a complex of cyclin-dependent kinase 5 and a novel brain-specific regulatory subunit. Nature 371: 423-425.
20. Liu F, Ma XH, Ule J, Bibb JA, Nishi A, Demaggio AJ et al (2001). Regulation of cyclin-dependent kinase 5 and casein kinase 1 by metabotropic glutamate receptors. Proc Natl Acad Sci 98: 11062-11068.
21. Lu L, Grimm JW, Shaham Y, Hope BT (2003). Molecular neuroadaptations in the accumbens and ventral tegmental area during the first 90 days of forced abstinence from cocaine self-administration in rats. J Neurochem 85: 1604-1613.
22. Maccioni RB, Otth C, Concha II, Munoz JP (2001). The protein kinase cdk5. Eur J Biochem 268: 1518-1527.
23. Nestler EJ (2001). Molecular basis of long-term plasticity underlying addiction. Nat Rev 2: 119-128.
24. Nestler EJ, Aghajanian GK (1997). Molecular and cellular basis of addiction. Science 278: 58-63.
25. Nishi A, Bibb JA, Matsuyama S, Hamada M, Higashi H, Nairn AC et al (2002). Regulation of DARPP-32 dephosphorylation at PKA-and cdk5-sites by NMDA and AMPA receptors: distinct roles of calcineurin and protein phosphatase-2A. J Neurochem 81: 832-841.
26. Nishi A, Bibb JA, Snyder G, Higashi H, Nairn AC, Greengard P (2000). Amplification of dopaminergic signaling by a positive feedback loop. Proc Natl Acad Sci 97: 12840-12845.
27. Norrholm SD, Bibb JA, Nestler EJ, Ouimet CC, Taylor JR, Greengard P (2003). Cocaine-induced proliferation of dendritic spines in nucleus accumbens is dependent on the activity of cyclin-dependent kinase-5. Neuroscience 116: 19-22.
28. Paxinos G, Watson C (1996). The Rat Atlas in Stereotaxic Coordinates. Academic Press: San Diego.
29. Robinson TE, Becker JB (1986). Enduring changes in brain and behavior produced by chronic amphetamine administration: a review and evaluation of animal models of amphetamine psychosis. Brain Res Rev 11: 157-198.
30. Robinson TE, Kolb B (1997). Persistent structural modifications in nucleus accumbens and prefrontal cortex neurons produced by previous experience with amphetamine. J Neurosci 17: 8491-8497.
31. Robinson TE, Kolb B (1999). Alternations in the morphology of dendrites and dendritic spines in the nucleus accumbens and prefrontal cortex following repeated treatment with amphetamine or cocaine. Eur J Neurosci 11: 1598-1604.
32. Self DW, Nestler EJ (1995). Molecular mechanisms of drug reinforcement and addiction. Annu Rev Neurosci 18: 463-495.
33. Sharma P, Sharma M, Amin ND, Albers RW, Pant HC (1999). Regulation of cyclin-dependent kinase 5 catalytic activity by phorphorylation. Proc Natl Acad Sci USA 96: 11156-11160.
34. Smith DS, Greer PL, Tsai LH (2001). Cdk5 on the brain. Cell Growth Diff 12: 277-283.
35. Smith DS, Tsai LH (2002). Cdk5 behind the wheel: a role in trafficking and transport? Trends Cell Biol 12: 28-36.
36. Svenningsson P, Nishi A, Fisone G, Girault J-A, Nairn AC, Greengard P (2004). DARPP-32: an integrator of neurotransmission. Annu Rev Pharmacol Toxicol 44: 269-296.
37. Todtenkopf MS, Stellar JR (2000). Assessment of tyrosine hydroxylase immunoreactive innervation in five subregions of the nucleus accumbens shell in rats treated with repeated cocaine. Synapse 38: 261-270.
38. Vanderschuren LJMJ, Kalivas PW (2000). Alterations in dopaminergic and glutamatergic transmission in the induction and expression of behavioral sensitization: a critical review of preclinical studies. Psychopharmacology 151: 99-120.
39. White FJ, Cooper DC (2001). The vicious cyclin of addiction. Nat Med 7: 416-418.