-
1
-
-
33845784758
-
Blood-brain barrier delivery
-
DOI 10.1016/j.drudis.2006.10.013, PII S1359644606004363
-
Pardridge WM. Blood-brain barrier delivery. Drug Discov Today 2007;12(1-2):54-61 (Pubitemid 46014479)
-
(2007)
Drug Discovery Today
, vol.12
, Issue.1-2
, pp. 54-61
-
-
Pardridge, W.M.1
-
2
-
-
34547645047
-
Modelling of the blood - Brain barrier in drug discovery and development
-
DOI 10.1038/nrd2368, PII NRD2368
-
Cecchelli R, Berezowski V, Lundquist S, et al. Modelling of the blood-brain barrier in drug discovery anddevelopment. Nat Rev Drug Discov 2007;6(8):650-61 (Pubitemid 47202487)
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.8
, pp. 650-661
-
-
Cecchelli, R.1
Berezowski, V.2
Lundquist, S.3
Culot, M.4
Renftel, M.5
Dehouck, M.-P.6
Fenart, L.7
-
3
-
-
80053558294
-
The ABC of the blood-brain barrier - Regulation of drug efflux pumps
-
Mahringer A, Ott M, Reimold I, et al. The ABC of the blood-brain barrier - regulation of drug efflux pumps.Curr Pharm Des 2011;17(26):2762-70
-
(2011)
Curr Pharm des
, vol.17
, Issue.26
, pp. 2762-2770
-
-
Mahringer, A.1
Ott, M.2
Reimold, I.3
-
4
-
-
0036234783
-
High-throughput and in silico techniques in drug metabolism and pharmacokinetics
-
van de Waterbeemd H. High-throughput and in silico techniques in drug metabolism and pharmacokinetics. Curr Opin Drug Discov Dev 2002;5(1):33-43
-
(2002)
Curr Opin Drug Discov Dev
, vol.5
, Issue.1
, pp. 33-43
-
-
Van De Waterbeemd, H.1
-
5
-
-
0037364162
-
ADMET in silico modelling: Towards prediction paradise?
-
DOI 10.1038/nrd1032
-
van de Waterbeemd H, Gifford E. ADMET in silico modelling: towards prediction paradise? Nat RevDrug Discov 2003;2(3):192-204 (Pubitemid 37361664)
-
(2003)
Nature Reviews Drug Discovery
, vol.2
, Issue.3
, pp. 192-204
-
-
Van De Waterbeemd, H.1
Gifford, E.2
-
6
-
-
33644896517
-
Preclinical pharmacokinetics: An approach towards safer and efficacious drugs
-
Singh SS. Preclinical pharmacokinetics: an approach towards safer and efficacious drugs. Curr Drug Metab 2006;7(2):165-82
-
(2006)
Curr Drug Metab
, vol.7
, Issue.2
, pp. 165-182
-
-
Singh, S.S.1
-
7
-
-
13444269007
-
Chemical modification of paclitaxel (taxol) reduces P-glycoprotein interactions and increases permeation across the blood-brain barrier in vitro and in situ
-
DOI 10.1021/jm040114b
-
Rice A, Liu Y, Michaelis ML, et al. Chemical modification of paclitaxel (Taxol) reduces P-glycoprotein interactions and increases permeation across the blood-brain barrier in vitro and in situ. J Med Chem2005;48(3):832-8 (Pubitemid 40209105)
-
(2005)
Journal of Medicinal Chemistry
, vol.48
, Issue.3
, pp. 832-838
-
-
Rice, A.1
Liu, Y.2
Michaelis, M.L.3
Himes, R.H.4
Georg, G.I.5
Audus, K.L.6
-
8
-
-
79960304811
-
Drug repurposing and adverse event prediction using high- throughputliterature analysis Wiley
-
Deftereos SN, Andronis C, Friedla EJ, Persidis A. Drug repurposing and adverse event prediction using high-throughputliterature analysis. Wiley Interdiscip Rev Syst Biol Med 2011;3(3):323-34
-
(2011)
Interdiscip Rev Syst Biol Med
, vol.3
, Issue.3
, pp. 323-334
-
-
Deftereos, S.N.1
Andronis, C.2
Friedla, E.J.3
Persidis, A.4
-
9
-
-
78650387939
-
Newperspectives on innovative drug discovery: An overview
-
Pan SY, Pan S, Yu ZL, et al. Newperspectives on innovative drug discovery: an overview. J Pharm PharmSci 2010;13(3):450-71
-
(2010)
J Pharm PharmSci
, vol.13
, Issue.3
, pp. 450-471
-
-
Pan, S.Y.1
Pan, S.2
Yu, Z.L.3
-
10
-
-
0037374498
-
The price of innovation: New estimates of drug development costs
-
DOI 10.1016/S0167-6296(02)00126-1
-
DiMasi JA, Hansen RW, Grabowski HG. The price of innovation: new estimates of drug development costs. J Health Econ 2003;22(2):151-85 (Pubitemid 36279392)
-
(2003)
Journal of Health Economics
, vol.22
, Issue.2
, pp. 151-185
-
-
DiMasi, J.A.1
Hansen, R.W.2
Grabowski, H.G.3
-
11
-
-
79952587191
-
The cost of drug development: A systematic review
-
Morgan S, Grootendorst P, Lexchin J, et al. The cost of drug development: a systematic review. Health Policy 2011;100(1):4-17
-
(2011)
Health Policy
, vol.100
, Issue.1
, pp. 4-17
-
-
Morgan, S.1
Grootendorst, P.2
Lexchin, J.3
-
12
-
-
0032832775
-
Drug screening-beyond the bottleneck
-
Dove A. Drug screening-beyond the bottleneck. Nat Biotechnol 1999;17(9):859-63
-
(1999)
Nat Biotechnol
, vol.17
, Issue.9
, pp. 859-863
-
-
Dove, A.1
-
13
-
-
0141958109
-
In silico prediction of blood-brain barrier permeation
-
DOI 10.1016/S1359-6446(03)02827-7, PII S1359644603028277
-
Clark DE. In silico prediction of blood-brain barrier permeation. Drug Discov Today 2003;8(20):927-33 (Pubitemid 37230012)
-
(2003)
Drug Discovery Today
, vol.8
, Issue.20
, pp. 927-933
-
-
Clark, D.E.1
-
14
-
-
79953845021
-
Multi-step usage of in vivo models during rational drug design and discovery
-
Williams CH, Hong CC. Multi-step usage of in vivo models during rational drug design and discovery. Int J Mol Sci2011;12(4):2262-74
-
(2011)
Int J Mol Sci
, vol.12
, Issue.4
, pp. 2262-2274
-
-
Williams, C.H.1
Hong, C.C.2
-
15
-
-
79960998682
-
Current concepts of blood-brain barrier development
-
Liebner S, Czupalla CJ, Wolburg H. Current concepts of blood-brain barrier development. Int J Dev Biol 2011;55(4-5):467-76
-
(2011)
Int J Dev Biol
, vol.55
, Issue.4-5
, pp. 467-476
-
-
Liebner, S.1
Czupalla, C.J.2
Wolburg, H.3
-
16
-
-
79954506893
-
Exploiting nutrient transporters at the blood-brain barrier to improve braindistribution of small molecules
-
Mittapalli RK, Manda VK, Adkins CE, et al. Exploiting nutrient transporters at the blood-brain barrier to improve braindistribution of small molecules. Ther Deliv 2011;1(6):775-84
-
(2011)
Ther Deliv
, vol.1
, Issue.6
, pp. 775-784
-
-
Mittapalli, R.K.1
Manda, V.K.2
Adkins, C.E.3
-
17
-
-
80053458900
-
Cerebral microvascular endothelium and the pathogenesis of neurodegenerative diseases
-
Grammas P, Martinez J, Miller B. Cerebral microvascular endothelium and the pathogenesis of neurodegenerative diseases. Expert Rev Mol Med 2011;13:e19
-
(2011)
Expert Rev Mol Med
, vol.13
-
-
Grammas, P.1
Martinez, J.2
Miller, B.3
-
19
-
-
17644364388
-
Dynamics of CNS barriers: Evolution, differentiation, and modulation
-
DOI 10.1007/s10571-004-1374-y
-
Abbott NJ. Dynamics of CNS barriers: evolution, differentiation, and modulation. Cell Mol Neurobiol2005;25(1):5-23 (Pubitemid 40558582)
-
(2005)
Cellular and Molecular Neurobiology
, vol.25
, Issue.1
, pp. 5-23
-
-
Abbott, N.J.1
-
20
-
-
0014481056
-
Junctions between intimately apposed cell membranes in the vertebrate brain
-
Brightman MW, Reese TS. Junctions between intimately apposed cell membranes in the vertebrate brain. J Cell Biol 1969;40(3):648-77
-
(1969)
J Cell Biol
, vol.40
, Issue.3
, pp. 648-677
-
-
Brightman, M.W.1
Reese, T.S.2
-
21
-
-
32344446371
-
Development of the blood-brain barrier: A historical point of view
-
DOI 10.1002/ar.b.20087
-
Ribatti D, Nico B, Crivellato E, Artico M. Development of the blood-brain barrier: a historical point ofview. Anat Rec B New Anat 2006;289(1):3-8 (Pubitemid 43219973)
-
(2006)
Anatomical Record - Part B New Anatomist
, vol.289
, Issue.1
, pp. 3-8
-
-
Ribatti, D.1
Nico, B.2
Crivellato, E.3
Artico, M.4
-
22
-
-
0025048342
-
Electrical resistance across the blood-brain barrier in anaesthetized rats: A developmental study
-
Butt AM, Jones HC, Abbott NJ. Electrical resistance across the blood-brain barrier in anaesthetized rats: a developmental study. J Physiol 1990;429:47-62 (Pubitemid 20327537)
-
(1990)
Journal of Physiology
, vol.429
, pp. 47-62
-
-
Butt, A.M.1
Jones, H.C.2
Abbott, N.J.3
-
23
-
-
79952450877
-
Drug delivery to the posterior segment of the eye
-
Thrimawithana TR, Young S, Bunt CR, et al. Drug delivery to the posterior segment of the eye. Drug Discov Today 2011;16(5-6):270-7
-
(2011)
Drug Discov Today
, vol.16
, Issue.5-6
, pp. 270-277
-
-
Thrimawithana, T.R.1
Young, S.2
Bunt, C.R.3
-
24
-
-
79957722029
-
The blood-retinal barrier: Structure and functional significance
-
Runkle EA, Antonetti DA. The blood-retinal barrier: structure and functional significance. Methods Mol Biol 2011;686:133-48
-
(2011)
Methods Mol Biol
, vol.686
, pp. 133-148
-
-
Runkle, E.A.1
Antonetti, D.A.2
-
25
-
-
60749087739
-
Assays to predict drug permeation across the blood-brainbarrier, and distribution to brain
-
Abbott NJ, Dolman DE, Patabendige AK. Assays to predict drug permeation across the blood-brainbarrier, and distribution to brain. Curr Drug Metab 2008;9(9):901-10
-
(2008)
Curr Drug Metab
, vol.9
, Issue.9
, pp. 901-910
-
-
Abbott, N.J.1
Dolman, D.E.2
Patabendige, A.K.3
-
26
-
-
79956326438
-
Transporter-mediated drug uptake and efflux: Important determinants of adverse drug reactions
-
Zolk O, Fromm MF. Transporter-mediated drug uptake and efflux: important determinants of adverse drug reactions. Clin Pharmacol Ther 2011;89(6):798-805
-
(2011)
Clin Pharmacol Ther
, vol.89
, Issue.6
, pp. 798-805
-
-
Zolk, O.1
Fromm, M.F.2
-
27
-
-
77949375780
-
Biopharmaceutical drug targeting to the brain
-
Pardridge WM. Biopharmaceutical drug targeting to the brain. J Drug Target 2010;18(3):157-67
-
(2010)
J Drug Target
, vol.18
, Issue.3
, pp. 157-167
-
-
Pardridge, W.M.1
-
28
-
-
78149477007
-
Regulation of ABC transporters at the blood-brain barrier: New targets for CNS therapy
-
Hartz AM, Bauer B. Regulation of ABC transporters at the blood-brain barrier: new targets for CNS therapy. Mol Interv 2010;10(5):293-304
-
(2010)
Mol Interv
, vol.10
, Issue.5
, pp. 293-304
-
-
Hartz, A.M.1
Bauer, B.2
-
29
-
-
77958025244
-
Structure and function of the human breast cancer resistance protein (BCRP/ ABCG2)
-
Ni Z, Bikadi Z, Rosenberg MF, Mao Q. Structure and function of the human breast cancer resistance protein (BCRP/ ABCG2). Curr Drug Metab 2010;11(7):603-17
-
(2010)
Curr Drug Metab
, vol.11
, Issue.7
, pp. 603-617
-
-
Ni, Z.1
Bikadi, Z.2
Rosenberg, M.F.3
Mao, Q.4
-
30
-
-
80053538365
-
Breast cancer resistance protein and P-glycoprotein in brain cancer: Two gatekeepers team up
-
Agarwal S, Hartz AM, Elmquist WF, Bauer B. Breast cancer resistance protein and P-glycoprotein in brain cancer: two gatekeepers team up. Curr Pharm Des 2011;17(26):2793-802
-
(2011)
Curr Pharm des
, vol.17
, Issue.26
, pp. 2793-2802
-
-
Agarwal, S.1
Hartz, A.M.2
Elmquist, W.F.3
Bauer, B.4
-
31
-
-
78649985708
-
Chronic exposure to nicotine and saquinavir decreases endothelial Notch-4 expression and disrupts blood-brain barrier integrity
-
Manda VK, Mittapalli RK, Geldenhuys WJ, Lockman PR. Chronic exposure to nicotine and saquinavir decreases endothelial Notch-4 expression and disrupts blood-brain barrier integrity. J Neurochem 2010;115(2):515-25
-
(2010)
J Neurochem
, vol.115
, Issue.2
, pp. 515-525
-
-
Manda, V.K.1
Mittapalli, R.K.2
Geldenhuys, W.J.3
Lockman, P.R.4
-
32
-
-
78650029674
-
Nicotine and cotinine increases the brain penetration of saquinavir in rat
-
Manda VK, Mittapalli RK, Bohn KA, et al. Nicotine and cotinine increases the brain penetration of saquinavir in rat. J Neurochem 2010;115(6):1495-507
-
(2010)
J Neurochem
, vol.115
, Issue.6
, pp. 1495-1507
-
-
Manda, V.K.1
Mittapalli, R.K.2
Bohn, K.A.3
-
33
-
-
80054697226
-
Brain-targeted delivery of paclitaxel using glutathione-coated nanoparticles for braincancers
-
Geldenhuys W, Mbimba T, Bui T, et al. Brain-targeted delivery of paclitaxel using glutathione-coated nanoparticles for braincancers. J Drug Target 2011;19(9):837-45
-
(2011)
J Drug Target
, vol.19
, Issue.9
, pp. 837-845
-
-
Geldenhuys, W.1
Mbimba, T.2
Bui, T.3
-
34
-
-
77951773926
-
Brain-targeted delivery of Tempol-loaded nanoparticles forneurological disorders
-
Carroll RT, Bhatia D, Geldenhuys W, et al. Brain-targeted delivery of Tempol-loaded nanoparticles forneurological disorders. J Drug Target 2010;18(9):665-74
-
(2010)
J Drug Target
, vol.18
, Issue.9
, pp. 665-674
-
-
Carroll, R.T.1
Bhatia, D.2
Geldenhuys, W.3
-
36
-
-
85081773422
-
Case study: Adapting in vitro blood-brain barrier models for use in early-stage drug discovery
-
in press
-
Vandenhaute E, Sevin E, Hallier-Vanuxeem D, et al. Case study: adapting in vitro blood-brain barrier models for use in early-stage drug discovery. Drug Discov Today 2011; in press
-
(2011)
Drug Discov Today
-
-
Vandenhaute, E.1
Sevin, E.2
Hallier-Vanuxeem, D.3
-
37
-
-
79959952037
-
Physiologic and anatomic characterization of the brain surface glia barrier of Drosophila
-
DeSalvo MK, Mayer N, Mayer F, Bainton RJ. Physiologic and anatomic characterization of the brain surface glia barrier of Drosophila. Glia 2011;59(9):1322-40
-
(2011)
Glia
, vol.59
, Issue.9
, pp. 1322-1340
-
-
Desalvo, M.K.1
Mayer, N.2
Mayer, F.3
Bainton, R.J.4
-
38
-
-
60949110463
-
A new blood-brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes
-
Nakagawa S, Deli MA, Kawaguchi H, et al. A new blood-brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes. Neurochem Int 2009;54(3-4):253-63
-
(2009)
Neurochem Int
, vol.54
, Issue.3-4
, pp. 253-263
-
-
Nakagawa, S.1
Deli, M.A.2
Kawaguchi, H.3
-
39
-
-
77950857749
-
The functional organisation of glia in the adult brain of Drosophila and otherinsects
-
Edwards TN, Meinertzhagen IA. The functional organisation of glia in the adult brain of Drosophila and otherinsects. Prog Neurobiol 2010;90(4):471-97
-
(2010)
Prog Neurobiol
, vol.90
, Issue.4
, pp. 471-497
-
-
Edwards, T.N.1
Meinertzhagen, I.A.2
-
40
-
-
63849265463
-
Evolutionary conservation of vertebrate blood-brain barrier chemoprotective mechanisms in Drosophila
-
Mayer F, Mayer N, Chinn L, et al. Evolutionary conservation of vertebrate blood-brain barrier chemoprotective mechanisms in Drosophila. J Neurosci 2009;29(11):3538-50
-
(2009)
J Neurosci
, vol.29
, Issue.11
, pp. 3538-3550
-
-
Mayer, F.1
Mayer, N.2
Chinn, L.3
-
41
-
-
79958230683
-
Models for predicting blood-brain barrier permeation
-
Nielsen PA, Andersson O, Hansen SH, et al. Models for predicting blood-brain barrier permeation. Drug Discov Today 2011;16(11-12):472-5
-
(2011)
Drug Discov Today
, vol.16
, Issue.11-12
, pp. 472-475
-
-
Nielsen, P.A.1
Andersson, O.2
Hansen, S.H.3
-
42
-
-
34248598584
-
Invertebrate animal models of diseases as screening tools in drug discovery
-
DOI 10.1021/cb700009m
-
Segalat L. Invertebrate animal models of diseases as screening tools in drug discovery. ACS Chem Biol 2007;2(4):231-6 (Pubitemid 47629209)
-
(2007)
ACS Chemical Biology
, vol.2
, Issue.4
, pp. 231-236
-
-
Segalat, L.1
-
43
-
-
0021962412
-
Embryonic development of glial cells and their junctions in the locust central nervous system
-
Swales LS, Lane NJ. Embryonic development of glial cells and their junctions in the locust central nervous system. J Neurosci 1985;5(1):117-27 (Pubitemid 15155676)
-
(1985)
Journal of Neuroscience
, vol.5
, Issue.1
, pp. 117-127
-
-
Swales, L.S.1
Lane, N.J.2
-
44
-
-
0000736476
-
Localization of the blood-brain barrier of an insect: Electrical model and analysis
-
Schofield PK, Threherne JE. Localization of the blood-brain barrier of an insect: electrical model and analysis. J Exp Biol 1984;109:319-31
-
(1984)
J Exp Biol
, vol.109
, pp. 319-331
-
-
Schofield, P.K.1
Threherne, J.E.2
-
45
-
-
34547698956
-
Neuron-glial interactions in blood-brain barrier formation
-
DOI 10.1146/annurev.neuro.30.051606.094345
-
Banerjee S, Bhat MA. Neuron-glial interactions in blood-brain barrier formation. Annu Rev Neurosci 2007;30:235-58 (Pubitemid 47218757)
-
(2007)
Annual Review of Neuroscience
, vol.30
, pp. 235-258
-
-
Banerjee, S.1
Bhat, M.A.2
-
46
-
-
10444264499
-
The molecular physiology of tight junction pores
-
Van Itallie CM, Anderson JM. The molecular physiology of tight junction pores. Physiology (Bethesda) 2004;19:331-8 (Pubitemid 39636080)
-
(2004)
Physiology
, Issue.6
, pp. 331-338
-
-
Van Itallie, C.M.1
Anderson, J.M.2
-
47
-
-
77951672406
-
High-throughput screening and small animal models, where are we?
-
Giacomotto J, Segalat L. High-throughput screening and small animal models, where are we? Br J Pharmacol 2010;160(2):204-16
-
(2010)
Br J Pharmacol
, vol.160
, Issue.2
, pp. 204-216
-
-
Giacomotto, J.1
Segalat, L.2
-
48
-
-
38549095461
-
Organization and function of the blood-brain barrier in Drosophila
-
DOI 10.1523/JNEUROSCI.4367-07.2008
-
Stork T, Engelen D, Krudewig A, et al. Organization and function of the blood-brain barrier in Drosophila.J Neurosci 2008;28(3):587-97 (Pubitemid 351159026)
-
(2008)
Journal of Neuroscience
, vol.28
, Issue.3
, pp. 587-597
-
-
Stork, T.1
Engelen, D.2
Krudewig, A.3
Silies, M.4
Bainton, R.J.5
Klambt, C.6
-
49
-
-
79955749505
-
Human disease models in Drosophila melanogaster and the role of the fly in therapeutic drug discovery
-
Pandey UB, Nichols CD. Human disease models in Drosophila melanogaster and the role of the fly in therapeutic drug discovery. Pharmacol Rev 2011;63(2):411-36
-
(2011)
Pharmacol Rev
, vol.63
, Issue.2
, pp. 411-436
-
-
Pandey, U.B.1
Nichols, C.D.2
-
50
-
-
79959345818
-
New animal models of Parkinson's disease
-
Dehay B, Bezard E. New animal models of Parkinson's disease. Mov Disord 2011;26(7):1198-205
-
(2011)
Mov Disord
, vol.26
, Issue.7
, pp. 1198-1205
-
-
Dehay, B.1
Bezard, E.2
-
51
-
-
80053152848
-
Inhibitors of LRRK2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in Caenorhabditis elegans and Drosophila Parkinson's disease models
-
Liu Z, Hamamichi S, Lee BD, et al. Inhibitors of LRRK2 kinase attenuate neurodegeneration and Parkinson-like phenotypes in Caenorhabditis elegans and Drosophila Parkinson's disease models. Hum Mol Genet 2011;20(20):3933-42
-
(2011)
Hum Mol Genet
, vol.20
, Issue.20
, pp. 3933-3942
-
-
Liu, Z.1
Hamamichi, S.2
Lee, B.D.3
-
52
-
-
26244436194
-
Moody encodes two GPCRs that regulate cocaine behaviors and blood-brain barrier permeability in Drosophila
-
DOI 10.1016/j.cell.2005.07.029, PII S0092867405007609
-
Bainton RJ, Tsai LT, Schwabe T, et al. moody encodes two GPCRs that regulate cocaine behaviors and blood-brain barrierpermeability in Drosophila. Cell 2005;123(1):145-56 (Pubitemid 41414535)
-
(2005)
Cell
, vol.123
, Issue.1
, pp. 145-156
-
-
Bainton, R.J.1
Tsai, L.T.-Y.2
Schwabe, T.3
DeSalvo, M.4
Gaul, U.5
Heberlein, U.6
-
53
-
-
79957714549
-
Novel models for studying the blood-brain and blood-eye barriers in Drosophila
-
Pinsonneault RL, Mayer N, Mayer F, et al. Novel models for studying the blood-brain and blood-eye barriers in Drosophila. Methods Mol Biol 2011;686:357-69
-
(2011)
Methods Mol Biol
, vol.686
, pp. 357-369
-
-
Pinsonneault, R.L.1
Mayer, N.2
Mayer, F.3
-
54
-
-
80053264881
-
Chemical screening in zebrafish for novel biological and therapeutic discovery
-
Tan JL, Zon LI. Chemical screening in zebrafish for novel biological and therapeutic discovery. Methods Cell Biol 2011;105:493-516
-
(2011)
Methods Cell Biol
, vol.105
, pp. 493-516
-
-
Tan, J.L.1
Zon, L.I.2
-
55
-
-
80053031246
-
A high-content screening assay in transgenic zebrafish identifies two novel activators of fgf signaling
-
Saydmohammed M, Vollmer LL, Onuoha EO, et al. A high-content screening assay in transgenic zebrafish identifies two novel activators of fgf signaling. Birth Defects Res C Embryo Today 2011;93(3):281-7
-
(2011)
Birth Defects Res C Embryo Today
, vol.93
, Issue.3
, pp. 281-287
-
-
Saydmohammed, M.1
Vollmer, L.L.2
Onuoha, E.O.3
-
56
-
-
84856972043
-
Behavioral screening for neuroactive drugs in zebrafish
-
Rihel J, Schier AF. Behavioral screening for neuroactive drugs in zebrafish. Dev Neurobiol 2012;72:373-85
-
(2012)
Dev Neurobiol
, vol.72
, pp. 373-385
-
-
Rihel, J.1
Schier, A.F.2
-
57
-
-
79955100665
-
Drug screening in a zebrafish model of Duchenne muscular dystrophy
-
Kawahara G, Karpf JA, Myers JA, et al. Drug screening in a zebrafish model of Duchenne muscular dystrophy. Proc Natl Acad Sci USA 2011;108(13):5331-6
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.13
, pp. 5331-5336
-
-
Kawahara, G.1
Karpf, J.A.2
Myers, J.A.3
-
58
-
-
77957867766
-
Identification of novel inhibitors of dietary lipid absorption using zebrafish
-
Clifton JD, Lucumi E, Myers MC, et al. Identification of novel inhibitors of dietary lipid absorption using zebrafish. PloS One 2010;5(8):e12386
-
(2010)
PloS One
, vol.5
, Issue.8
-
-
Clifton, J.D.1
Lucumi, E.2
Myers, M.C.3
-
59
-
-
80052972631
-
The developing zebrafish (Danio rerio): A vertebrate model for high-throughput screening of chemicallibraries
-
Lessman CA. The developing zebrafish (Danio rerio): a vertebrate model for high-throughput screening of chemicallibraries. Birth Defects Res C Embryo Today 2011;93(3):268-80
-
(2011)
Birth Defects Res C Embryo Today
, vol.93
, Issue.3
, pp. 268-280
-
-
Lessman, C.A.1
-
60
-
-
79961129490
-
Evaluation of spontaneous propulsive movement as a screening tool to detect rescue of Parkinsonism phenotypes in zebrafish models
-
Farrell TC, Cario CL, Milanese C, et al. Evaluation of spontaneous propulsive movement as a screening tool to detect rescue of Parkinsonism phenotypes in zebrafish models. Neurobiol Dis 2011;44(1):9-18
-
(2011)
Neurobiol Dis
, vol.44
, Issue.1
, pp. 9-18
-
-
Farrell, T.C.1
Cario, C.L.2
Milanese, C.3
-
61
-
-
40749095640
-
Functional and developmental analysis of the blood-brain barrier in zebrafish
-
Jeong JY, Kwon HB, Ahn JC, et al. Functional and developmental analysis of the blood-brain barrier in zebrafish. Brain Res Bull 2008;75(5):619-28
-
(2008)
Brain Res Bull
, vol.75
, Issue.5
, pp. 619-628
-
-
Jeong, J.Y.1
Kwon, H.B.2
Ahn, J.C.3
-
62
-
-
77954765192
-
A novel transgenic zebrafish model for blood-brain and blood-retinal barrier development
-
Xie J, Farage E, Sugimoto M, Anand-Apte B. A novel transgenic zebrafish model for blood-brain and blood-retinal barrier development. BMC Dev Biol 2010;10:76
-
(2010)
BMC Dev Biol
, vol.10
, pp. 76
-
-
Xie, J.1
Farage, E.2
Sugimoto, M.3
Anand-Apte, B.4
-
63
-
-
78650378532
-
Heterogeneous blood-tumor barrier permeability determines drug efficacy in experimental brain metastases of breast cancer
-
Lockman PR, Mittapalli RK, Taskar KS, et al. Heterogeneous blood-tumor barrier permeability determines drug efficacy in experimental brain metastases of breast cancer. Clin Cancer Res 2010;16(23):5664-78
-
(2010)
Clin Cancer Res
, vol.16
, Issue.23
, pp. 5664-5678
-
-
Lockman, P.R.1
Mittapalli, R.K.2
Taskar, K.S.3
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