-
1
-
-
71749090438
-
Synthesis and pharmacological exploitation of clioquinol-derived copper-binding apoptosis inducers triggering reactive oxygen species generation and MAPK pathway activation
-
Chen HL, Chang CY, Lee HT, Lin HH, Lu PJ, Yang CN, Shiau CW, Shaw AY. 2009. Synthesis and pharmacological exploitation of clioquinol-derived copper-binding apoptosis inducers triggering reactive oxygen species generation and MAPK pathway activation. Bioorg Med Chem 17: 7239-7247.
-
(2009)
Bioorg Med Chem
, vol.17
, pp. 7239-7247
-
-
Chen, H.L.1
Chang, C.Y.2
Lee, H.T.3
Lin, H.H.4
Lu, P.J.5
Yang, C.N.6
Shiau, C.W.7
Shaw, A.Y.8
-
2
-
-
79951663595
-
Dynamic smad-mediated BMP signaling revealed through transgenic zebrafish
-
Collery RF, Link BA. 2011. Dynamic smad-mediated BMP signaling revealed through transgenic zebrafish. Dev Dyn 240: 712-722.
-
(2011)
Dev Dyn
, vol.240
, pp. 712-722
-
-
Collery, R.F.1
Link, B.A.2
-
3
-
-
77952579630
-
Inhibition of histone deacetylase expands the renal progenitor cell population
-
de Groh ED, Swanhart LM, Cosentino CC, Jackson RL, Dai W, Kitchens CA, Day BW, Smithgall TE, Hukriede NA. 2010. Inhibition of histone deacetylase expands the renal progenitor cell population. J Am Soc Nephrol 21: 794-802.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 794-802
-
-
de Groh, E.D.1
Swanhart, L.M.2
Cosentino, C.C.3
Jackson, R.L.4
Dai, W.5
Kitchens, C.A.6
Day, B.W.7
Smithgall, T.E.8
Hukriede, N.A.9
-
4
-
-
28244480364
-
Chemical genetics: drug screens in zebrafish
-
den Hertog J. 2005. Chemical genetics: drug screens in zebrafish. Biosci Rep 25: 289-297.
-
(2005)
Biosci Rep
, vol.25
, pp. 289-297
-
-
den Hertog, J.1
-
5
-
-
3242886400
-
Fgf signalling controls the dorsoventral patterning of the zebrafish embryo
-
Furthauer M, Van Celst J, Thisse C, Thisse B. 2004. Fgf signalling controls the dorsoventral patterning of the zebrafish embryo. Development 131: 2853-2864.
-
(2004)
Development
, vol.131
, pp. 2853-2864
-
-
Furthauer, M.1
Van Celst, J.2
Thisse, C.3
Thisse, B.4
-
7
-
-
78649757232
-
Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin alpha1-antitrypsin Z
-
Gosai SJ, Kwak JH, Luke CJ, Long OS, King DE, Kovatch KJ, Johnston PA, Shun TY, Lazo JS, Perlmutter DH, Silverman GA, Pak SC. 2010. Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin alpha1-antitrypsin Z. PLoS One 5: e15460.
-
(2010)
PLoS One
, vol.5
-
-
Gosai, S.J.1
Kwak, J.H.2
Luke, C.J.3
Long, O.S.4
King, D.E.5
Kovatch, K.J.6
Johnston, P.A.7
Shun, T.Y.8
Lazo, J.S.9
Perlmutter, D.H.10
Silverman, G.A.11
Pak, S.C.12
-
8
-
-
79251604303
-
Quinolones: from antibiotics to autoinducers
-
Heeb S, Fletcher MP, Chhabra SR, Diggle SP, Williams P, Camara M. 2011. Quinolones: from antibiotics to autoinducers. FEMS Microbiol Rev 35: 247-274.
-
(2011)
FEMS Microbiol Rev
, vol.35
, pp. 247-274
-
-
Heeb, S.1
Fletcher, M.P.2
Chhabra, S.R.3
Diggle, S.P.4
Williams, P.5
Camara, M.6
-
9
-
-
52949092707
-
Selective inhibition of mitogen-activated protein kinase phosphatases by zinc accounts for extracellular signal-regulated kinase 1/2-dependent oxidative neuronal cell death
-
Ho Y, Samarasinghe R, Knoch ME, Lewis M, Aizenman E, DeFranco DB. 2008. Selective inhibition of mitogen-activated protein kinase phosphatases by zinc accounts for extracellular signal-regulated kinase 1/2-dependent oxidative neuronal cell death. Mol Pharmacol 74: 1141-1151.
-
(2008)
Mol Pharmacol
, vol.74
, pp. 1141-1151
-
-
Ho, Y.1
Samarasinghe, R.2
Knoch, M.E.3
Lewis, M.4
Aizenman, E.5
DeFranco, D.B.6
-
10
-
-
4344636300
-
A transposon-mediated gene trap approach identifies developmentally regulated genes in zebrafish
-
Kawakami K, Takeda H, Kawakami N, Kobayashi M, Matsuda N, Mishina M. 2004. A transposon-mediated gene trap approach identifies developmentally regulated genes in zebrafish. Dev Cell 7: 133-144.
-
(2004)
Dev Cell
, vol.7
, pp. 133-144
-
-
Kawakami, K.1
Takeda, H.2
Kawakami, N.3
Kobayashi, M.4
Matsuda, N.5
Mishina, M.6
-
11
-
-
43049101029
-
Dual-specificity MAP kinase phosphatases (MKPs) and cancer
-
Keyse SM. 2008. Dual-specificity MAP kinase phosphatases (MKPs) and cancer. Cancer Metastasis Rev 27: 253-261.
-
(2008)
Cancer Metastasis Rev
, vol.27
, pp. 253-261
-
-
Keyse, S.M.1
-
12
-
-
0036534583
-
Inhibition of BMP activity by the FGF signal promotes posterior neural development in zebrafish
-
Koshida S, Shinya M, Nikaido M, Ueno N, Schulte-Merker S, Kuroiwa A, Takeda H. 2002. Inhibition of BMP activity by the FGF signal promotes posterior neural development in zebrafish. Dev Biol 244: 9-20.
-
(2002)
Dev Biol
, vol.244
, pp. 9-20
-
-
Koshida, S.1
Shinya, M.2
Nikaido, M.3
Ueno, N.4
Schulte-Merker, S.5
Kuroiwa, A.6
Takeda, H.7
-
13
-
-
0026337851
-
Expression of the zebrafish paired box gene pax"zf-b" during early neurogenesis
-
Krauss S, Johansen T, Korzh V, Fjose A. 1991. Expression of the zebrafish paired box gene pax"zf-b" during early neurogenesis. Development 113: 1193-1206.
-
(1991)
Development
, vol.113
, pp. 1193-1206
-
-
Krauss, S.1
Johansen, T.2
Korzh, V.3
Fjose, A.4
-
14
-
-
0035214296
-
A gene expression screen in zebrafish embryogenesis
-
Kudoh T, Tsang M, Hukriede NA, Chen X, Dedekian M, Clarke CJ, Kiang A, Schultz S, Epstein JA, Toyama R, Dawid IB. 2001. A gene expression screen in zebrafish embryogenesis. Genome Res 11: 1979-1987.
-
(2001)
Genome Res
, vol.11
, pp. 1979-1987
-
-
Kudoh, T.1
Tsang, M.2
Hukriede, N.A.3
Chen, X.4
Dedekian, M.5
Clarke, C.J.6
Kiang, A.7
Schultz, S.8
Epstein, J.A.9
Toyama, R.10
Dawid, I.B.11
-
15
-
-
79951643123
-
Dynamic analysis of BMP-responsive smad activity in live zebrafish embryos
-
Laux DW, Febbo JA, Roman BL. 2011. Dynamic analysis of BMP-responsive smad activity in live zebrafish embryos. Dev Dyn 240: 682-694.
-
(2011)
Dev Dyn
, vol.240
, pp. 682-694
-
-
Laux, D.W.1
Febbo, J.A.2
Roman, B.L.3
-
16
-
-
77149154314
-
Reiterative use of the notch signal during zebrafish intrahepatic biliary development
-
Lorent K, Moore JC, Siekmann AF, Lawson N, Pack M. 2010. Reiterative use of the notch signal during zebrafish intrahepatic biliary development. Dev Dyn 239: 855-864.
-
(2010)
Dev Dyn
, vol.239
, pp. 855-864
-
-
Lorent, K.1
Moore, J.C.2
Siekmann, A.F.3
Lawson, N.4
Pack, M.5
-
17
-
-
32344448950
-
Statistical practice in high-throughput screening data analysis
-
Malo N, Hanley JA, Cerquozzi S, Pelletier J, Nadon R. 2006. Statistical practice in high-throughput screening data analysis. Nat Biotechnol 24: 167-175.
-
(2006)
Nat Biotechnol
, vol.24
, pp. 167-175
-
-
Malo, N.1
Hanley, J.A.2
Cerquozzi, S.3
Pelletier, J.4
Nadon, R.5
-
18
-
-
69249210903
-
Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages
-
Molina G, Vogt A, Bakan A, Dai W, Queiroz de Oliveira P, Znosko W, Smithgall TE, Bahar I, Lazo JS, Day BW, Tsang M. 2009. Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages. Nat Chem Biol 5: 680-687.
-
(2009)
Nat Chem Biol
, vol.5
, pp. 680-687
-
-
Molina, G.1
Vogt, A.2
Bakan, A.3
Dai, W.4
Queiroz de Oliveira, P.5
Znosko, W.6
Smithgall, T.E.7
Bahar, I.8
Lazo, J.S.9
Day, B.W.10
Tsang, M.11
-
19
-
-
34347373889
-
Generation of FGF reporter transgenic zebrafish and their utility in chemical screens
-
Molina GA, Watkins SC, Tsang M. 2007. Generation of FGF reporter transgenic zebrafish and their utility in chemical screens. BMC Dev Biol 7: 62.
-
(2007)
BMC Dev Biol
, vol.7
, pp. 62
-
-
Molina, G.A.1
Watkins, S.C.2
Tsang, M.3
-
20
-
-
33751032262
-
A chemical genetic screen for cell cycle inhibitors in zebrafish embryos
-
Murphey RD, Stern HM, Straub CT, Zon LI. 2006. A chemical genetic screen for cell cycle inhibitors in zebrafish embryos. Chem Biol Drug Des 68: 213-219.
-
(2006)
Chem Biol Drug Des
, vol.68
, pp. 213-219
-
-
Murphey, R.D.1
Stern, H.M.2
Straub, C.T.3
Zon, L.I.4
-
21
-
-
34250883337
-
Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis
-
North TE, Goessling W, Walkley CR, Lengerke C, Kopani KR, Lord AM, Weber GJ, Bowman TV, Jang IH, Grosser T, Fitzgerald GA, Daley GQ, Orkin SH, Zon LI. 2007. Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature 447: 1007-1011.
-
(2007)
Nature
, vol.447
, pp. 1007-1011
-
-
North, T.E.1
Goessling, W.2
Walkley, C.R.3
Lengerke, C.4
Kopani, K.R.5
Lord, A.M.6
Weber, G.J.7
Bowman, T.V.8
Jang, I.H.9
Grosser, T.10
Fitzgerald, G.A.11
Daley, G.Q.12
Orkin, S.H.13
Zon, L.I.14
-
22
-
-
70349487183
-
Notch-responsive cells initiate the secondary transition in larval zebrafish pancreas
-
Parsons MJ, Pisharath H, Yusuff S, Moore JC, Siekmann AF, Lawson N, Leach SD. 2009. Notch-responsive cells initiate the secondary transition in larval zebrafish pancreas. Mech Dev 126: 898-912.
-
(2009)
Mech Dev
, vol.126
, pp. 898-912
-
-
Parsons, M.J.1
Pisharath, H.2
Yusuff, S.3
Moore, J.C.4
Siekmann, A.F.5
Lawson, N.6
Leach, S.D.7
-
23
-
-
0035162208
-
Retinoic acid-mediated gene expression in transgenic reporter zebrafish
-
Perz-Edwards A, Hardison NL, Linney E. 2001. Retinoic acid-mediated gene expression in transgenic reporter zebrafish. Dev Biol 229: 89-101.
-
(2001)
Dev Biol
, vol.229
, pp. 89-101
-
-
Perz-Edwards, A.1
Hardison, N.L.2
Linney, E.3
-
24
-
-
0034700166
-
Small molecule developmental screens reveal the logic and timing of vertebrate development
-
Peterson RT, Link BA, Dowling JE, Schreiber SL. 2000. Small molecule developmental screens reveal the logic and timing of vertebrate development. Proc Natl Acad Sci U S A 97: 12965-12969.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 12965-12969
-
-
Peterson, R.T.1
Link, B.A.2
Dowling, J.E.3
Schreiber, S.L.4
-
25
-
-
0026799212
-
Comparative analysis of Pax-2 protein distributions during neurulation in mice and zebrafish
-
Puschel AW, Westerfield M, Dressler GR. 1992. Comparative analysis of Pax-2 protein distributions during neurulation in mice and zebrafish. Mech Dev 38: 197-208.
-
(1992)
Mech Dev
, vol.38
, pp. 197-208
-
-
Puschel, A.W.1
Westerfield, M.2
Dressler, G.R.3
-
27
-
-
63849273196
-
The characterization of a zebrafish mid-hindbrain mutant, mid-hindbrain gone (mgo)
-
Shima T, Znosko W, Tsang M. 2009. The characterization of a zebrafish mid-hindbrain mutant, mid-hindbrain gone (mgo). Dev Dyn 238: 899-907.
-
(2009)
Dev Dyn
, vol.238
, pp. 899-907
-
-
Shima, T.1
Znosko, W.2
Tsang, M.3
-
28
-
-
33644788489
-
Small molecules that delay S phase suppress a zebrafish bmyb mutant
-
Stern HM, Murphey RD, Shepard JL, Amatruda JF, Straub CT, Pfaff KL, Weber G, Tallarico JA, King RW, Zon LI. 2005. Small molecules that delay S phase suppress a zebrafish bmyb mutant. Nat Chem Biol 1: 366-370.
-
(2005)
Nat Chem Biol
, vol.1
, pp. 366-370
-
-
Stern, H.M.1
Murphey, R.D.2
Shepard, J.L.3
Amatruda, J.F.4
Straub, C.T.5
Pfaff, K.L.6
Weber, G.7
Tallarico, J.A.8
King, R.W.9
Zon, L.I.10
-
29
-
-
77950531348
-
Characterization of an lhx1a transgenic reporter in zebrafish
-
Swanhart LM, Takahashi N, Jackson RL, Gibson GA, Watkins SC, Dawid IB, Hukriede NA. 2010. Characterization of an lhx1a transgenic reporter in zebrafish. Int J Dev Biol 54: 731-736.
-
(2010)
Int J Dev Biol
, vol.54
, pp. 731-736
-
-
Swanhart, L.M.1
Takahashi, N.2
Jackson, R.L.3
Gibson, G.A.4
Watkins, S.C.5
Dawid, I.B.6
Hukriede, N.A.7
-
30
-
-
62949098600
-
Chemical genomics identifies compounds affecting Xenopus laevis pigment cell development
-
Tomlinson ML, Rejzek M, Fidock M, Field RA, Wheeler GN. 2009. Chemical genomics identifies compounds affecting Xenopus laevis pigment cell development. Mol Biosyst 5: 376-384.
-
(2009)
Mol Biosyst
, vol.5
, pp. 376-384
-
-
Tomlinson, M.L.1
Rejzek, M.2
Fidock, M.3
Field, R.A.4
Wheeler, G.N.5
-
31
-
-
77956683205
-
Zebrafish: A tool for chemical screens
-
Tsang M. 2010. Zebrafish: A tool for chemical screens. Birth Defects Res C Embryo Today 90: 185-192.
-
(2010)
Birth Defects Res C Embryo Today
, vol.90
, pp. 185-192
-
-
Tsang, M.1
-
32
-
-
3242885066
-
A role for MKP3 in axial patterning of the zebrafish embryo
-
Tsang M, Maegawa S, Kiang A, Habas R, Weinberg E, Dawid IB. 2004. A role for MKP3 in axial patterning of the zebrafish embryo. Development 131: 2769-2779.
-
(2004)
Development
, vol.131
, pp. 2769-2779
-
-
Tsang, M.1
Maegawa, S.2
Kiang, A.3
Habas, R.4
Weinberg, E.5
Dawid, I.B.6
-
33
-
-
79951724667
-
Cardioprotective effect of zinc requires ErbB2 and Akt during hypoxia/reoxygenation
-
Viswanath K, Bodiga S, Balogun V, Zhang A, Bodiga VL. 2011. Cardioprotective effect of zinc requires ErbB2 and Akt during hypoxia/reoxygenation. Biometals 24: 171-180.
-
(2011)
Biometals
, vol.24
, pp. 171-180
-
-
Viswanath, K.1
Bodiga, S.2
Balogun, V.3
Zhang, A.4
Bodiga, V.L.5
-
34
-
-
61649105020
-
Automated image-based phenotypic analysis in zebrafish embryos
-
Vogt A, Cholewinski A, Shen X, Nelson SG, Lazo JS, Tsang M, Hukriede NA. 2009. Automated image-based phenotypic analysis in zebrafish embryos. Dev Dyn 238: 656-663.
-
(2009)
Dev Dyn
, vol.238
, pp. 656-663
-
-
Vogt, A.1
Cholewinski, A.2
Shen, X.3
Nelson, S.G.4
Lazo, J.S.5
Tsang, M.6
Hukriede, N.A.7
-
35
-
-
80355140624
-
-
Development of automated imaging and analysis for zebrafish chemical screens. JoVE 40
-
Vogt A, Codore H, Day BW, Hukriede N, Tsang M. 2010. Development of automated imaging and analysis for zebrafish chemical screens. JoVE 40.
-
(2010)
-
-
Vogt, A.1
Codore, H.2
Day, B.W.3
Hukriede, N.4
Tsang, M.5
-
36
-
-
34249288309
-
Implementation of high-content assay for inhibitors of mitogen-activated protein kinase phosphatases
-
Vogt A, Lazo JS. 2007. Implementation of high-content assay for inhibitors of mitogen-activated protein kinase phosphatases. Methods 42: 268-277.
-
(2007)
Methods
, vol.42
, pp. 268-277
-
-
Vogt, A.1
Lazo, J.S.2
-
37
-
-
78650723871
-
The Rho kinase Rock2b establishes anteroposterior asymmetry of the ciliated Kupffer's vesicle in zebrafish
-
Wang G, Cadwallader AB, Jang DS, Tsang M, Yost HJ, Amack JD. 2011. The Rho kinase Rock2b establishes anteroposterior asymmetry of the ciliated Kupffer's vesicle in zebrafish. Development 138: 45-54.
-
(2011)
Development
, vol.138
, pp. 45-54
-
-
Wang, G.1
Cadwallader, A.B.2
Jang, D.S.3
Tsang, M.4
Yost, H.J.5
Amack, J.D.6
-
38
-
-
79953064886
-
DHODH modulates transcriptional elongation in the neural crest and melanoma
-
White RM, Cech J, Ratanasirintrawoot S, Lin CY, Rahl PB, Burke CJ, Langdon E, Tomlinson ML, Mosher J, Kaufman C, Chen F, Long HK, Kramer M, Datta S, Neuberg D, Granter S, Young RA, Morrison S, Wheeler GN, Zon LI. 2011. DHODH modulates transcriptional elongation in the neural crest and melanoma. Nature 471: 518-522.
-
(2011)
Nature
, vol.471
, pp. 518-522
-
-
White, R.M.1
Cech, J.2
Ratanasirintrawoot, S.3
Lin, C.Y.4
Rahl, P.B.5
Burke, C.J.6
Langdon, E.7
Tomlinson, M.L.8
Mosher, J.9
Kaufman, C.10
Chen, F.11
Long, H.K.12
Kramer, M.13
Datta, S.14
Neuberg, D.15
Granter, S.16
Young, R.A.17
Morrison, S.18
Wheeler, G.N.19
Zon, L.I.20
more..
-
39
-
-
0032523782
-
Specification of the hindbrain fate in the zebrafish
-
Woo K, Fraser SE. 1998. Specification of the hindbrain fate in the zebrafish. Dev Biol 197: 283-296.
-
(1998)
Dev Biol
, vol.197
, pp. 283-296
-
-
Woo, K.1
Fraser, S.E.2
-
40
-
-
62649165022
-
Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation
-
Yeh JR, Munson KM, Elagib KE, Goldfarb AN, Sweetser DA, Peterson RT. 2009. Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation. Nat Chem Biol 5: 236-243.
-
(2009)
Nat Chem Biol
, vol.5
, pp. 236-243
-
-
Yeh, J.R.1
Munson, K.M.2
Elagib, K.E.3
Goldfarb, A.N.4
Sweetser, D.A.5
Peterson, R.T.6
-
41
-
-
33947167826
-
A pair of new statistical parameters for quality control in RNA interference high-throughput screening assays
-
Zhang XD. 2007. A pair of new statistical parameters for quality control in RNA interference high-throughput screening assays. Genomics 89: 552-561.
-
(2007)
Genomics
, vol.89
, pp. 552-561
-
-
Zhang, X.D.1
-
42
-
-
44849083214
-
Novel analytic criteria and effective plate designs for quality control in genome-scale RNAi screens
-
Zhang XD. 2008. Novel analytic criteria and effective plate designs for quality control in genome-scale RNAi screens. J Biomol Screen 13: 363-377.
-
(2008)
J Biomol Screen
, vol.13
, pp. 363-377
-
-
Zhang, X.D.1
-
43
-
-
77952585199
-
Overlapping functions of Pea3 ETS transcription factors in FGF signaling during zebrafish development
-
Znosko WA, Yu S, Thomas K, Molina GA, Li C, Tsang W, Dawid IB, Moon AM, Tsang M. 2010. Overlapping functions of Pea3 ETS transcription factors in FGF signaling during zebrafish development. Dev Biol 342: 11-25.
-
(2010)
Dev Biol
, vol.342
, pp. 11-25
-
-
Znosko, W.A.1
Yu, S.2
Thomas, K.3
Molina, G.A.4
Li, C.5
Tsang, W.6
Dawid, I.B.7
Moon, A.M.8
Tsang, M.9
-
44
-
-
12144273121
-
In vivo drug discovery in the zebrafish
-
Zon LI, Peterson RT. 2005. In vivo drug discovery in the zebrafish. Nat Rev Drug Discov 4: 35-44.
-
(2005)
Nat Rev Drug Discov
, vol.4
, pp. 35-44
-
-
Zon, L.I.1
Peterson, R.T.2
|