Evaluation of spontaneous propulsive movement as a screening tool to detect rescue of Parkinsonism phenotypes in zebrafish models

Neurobiology of Disease

Volumn 44, Issue 1, 2011, Pages 9-18

  Farrell, Thomas C ^a   Cario, Clinton L ^a   Milanese, Chiara ^a,c   Vogt, Andreas ^a   Jeong, Jong Hyeon ^b   Burton, Edward A ^a,d  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^c RiMED Foundation   (Italy)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Apomorphine; Automated behavior measurement; Chlorpromazine; Dopamine; Drug discovery; Haloperidol; Motor function; MPP+; Parkinsonism; Ropnirole; Spontaneous movement; Zebrafish

Indexed keywords

CHLORPROMAZINE; HALOPERIDOL;

AGE DISTRIBUTION; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOPAMINERGIC TRANSMISSION; EMBRYO; EVALUATION RESEARCH; HEREDITY; LARVAL STAGE; LOCOMOTION; MOTOR DEVELOPMENT; MOTOR DYSFUNCTION; NEUROMODULATION; NONHUMAN; PARKINSONISM; PRIORITY JOURNAL; PROPULSIVE MOVEMENT; SCREENING TEST; SIGNAL TRANSDUCTION; VELOCITY; ZEBRA FISH;

ANALYSIS OF VARIANCE; ANIMALS; ARTIFACTS; DOPAMINE; LARVA; LOCOMOTION; PARKINSONIAN DISORDERS; PHENOTYPE; REPRODUCIBILITY OF RESULTS; SYNAPTIC TRANSMISSION; VIDEO RECORDING; ZEBRAFISH;

EID: 79961129490     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2011.05.016     Document Type: Article

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