메뉴 건너뛰기




Volumn 31, Issue 3, 2012, Pages 276-286

Meloxicam modulates oxidative stress status, inhibits prostaglandin E2, and abrogates apoptosis in carbon tetrachloride-induced rat hepatic injury

Author keywords

carbon tetrachloride; cycloxegenase 2; meloxicam; oxidative stress

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CARBON TETRACHLORIDE; CATALASE; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; GLUTATHIONE; GLUTATHIONE TRANSFERASE; MALONALDEHYDE; MELOXICAM; PROSTAGLANDIN E2; SUPEROXIDE DISMUTASE;

EID: 84862013891     PISSN: 10915818     EISSN: 1092874X     Source Type: Journal    
DOI: 10.1177/1091581812442939     Document Type: Article
Times cited : (31)

References (78)
  • 1
    • 0038072977 scopus 로고    scopus 로고
    • Carbon tetrachloride-induced lipid peroxidation: Eicosanoid formation and their regulation by antioxidant nutrients
    • DOI 10.1016/S0300-483X(03)00157-4
    • Basu S. Carbon tetrachloride-induced lipid peroxidation: eicosanoid formation and their regulation by antioxidant nutrients. Toxicol. 2003;189(1-2):113-127. (Pubitemid 36725027)
    • (2003) Toxicology , vol.189 , Issue.1-2 , pp. 113-127
    • Basu, S.1
  • 2
    • 0038549756 scopus 로고
    • Carbon tetrachloride poisoning; a review
    • Hardin BL. Carbon tetrachloride poisoning; a review. Ind Med Surg. 1954;23(3):93-105.
    • (1954) Ind Med Surg , vol.23 , Issue.3 , pp. 93-105
    • Hardin, B.L.1
  • 3
    • 0020698041 scopus 로고
    • Hepatic lipid peroxidation in vivo in rats with chronic iron overload
    • Bacon BR, Tavill AS, Brittenham GM, Park CH, Recknagel RO. Hepatic lipid peroxidation in vivo in rats with chronic iron overload. J Clin Invest. 1983;71(3):429-439. (Pubitemid 13160788)
    • (1983) Journal of Clinical Investigation , vol.71 , Issue.3 , pp. 429-439
    • Bacon, B.R.1    Tavill, A.S.2    Brittenham, G.M.3
  • 5
    • 0037256608 scopus 로고    scopus 로고
    • Hepatotoxicity and mechanism of action of haloalkanes: Carbon tetrachloride as a toxicological model
    • Weber LW, Boll M, Stampfl A. Hepatotoxicity and mechanism of action of haloalkanes: carbon tetrachloride as a toxicological model. Crit Rev Toxicol. 2003;33(2):105-136. (Pubitemid 36432872)
    • (2003) Critical Reviews in Toxicology , vol.33 , Issue.2 , pp. 105-136
    • Weber, L.W.D.1    Boll, M.2    Stampfl, A.3
  • 6
    • 73349140526 scopus 로고    scopus 로고
    • Carbon tetrachloride-induced liver disease in rats: The potential effect of supplement oils with vitamins e and C on the nutritional status
    • Ismail RS, El-Megeid AA, Abdel-Moemin AR. Carbon tetrachloride-induced liver disease in rats: the potential effect of supplement oils with vitamins E and C on the nutritional status. Ger Med Sci. 2009;7:1612-3174.
    • (2009) Ger Med Sci , vol.7 , pp. 1612-3174
    • Ismail, R.S.1    El-Megeid, A.A.2    Abdel-Moemin, A.R.3
  • 7
    • 0142011656 scopus 로고    scopus 로고
    • Hepatoprotective mechanism of schisandrin B: Role of mitochondrial glutathione antioxidant status and heat shock proteins
    • DOI 10.1016/S0891-5849(03)00274-0
    • Chiu PY, Tang MH, Mak DH, Poon MK, Ko KM. Hepatoprotective mechanism of schisandrin B: role of mitochondrial glutathione antioxidant status and heat shock proteins. Free Radic Biol Med. 2003;35(4):368-380. (Pubitemid 37289167)
    • (2003) Free Radical Biology and Medicine , vol.35 , Issue.4 , pp. 368-380
    • Chiu, P.Y.1    Tang, M.H.2    Mak, D.H.F.3    Poon, M.K.T.4    Ko, K.M.5
  • 8
    • 0033859612 scopus 로고    scopus 로고
    • Flavonoids as antioxidants
    • Pietta PG. Flavonoids as antioxidants. J Nat Prod. 2000;63(7):1035-1042.
    • (2000) J Nat Prod , vol.63 , Issue.7 , pp. 1035-1042
    • Pietta, P.G.1
  • 9
    • 23944493587 scopus 로고    scopus 로고
    • Vitamin E, oxidative stress, and inflammation
    • DOI 10.1146/annurev.nutr.24.012003.132446
    • Singh U, Devaraj S, Jialal I. Vitamin E, oxidative stress, and inflammation. Annu Rev Nutr. 2005;25:151-174. (Pubitemid 41208998)
    • (2005) Annual Review of Nutrition , vol.25 , pp. 151-174
    • Singh, U.1    Devaraj, S.2    Jialal, I.3
  • 11
    • 34748858784 scopus 로고    scopus 로고
    • Oxidative stress and apoptosis: Impact on cancer therapy
    • DOI 10.1002/jps.20874
    • Ozben T. Oxidative stress and apoptosis: impact on cancer therapy. J Pharm Sci. 2007;96(9):2181-2196. (Pubitemid 47477879)
    • (2007) Journal of Pharmaceutical Sciences , vol.96 , Issue.9 , pp. 2181-2196
    • Ozben, T.1
  • 12
    • 61449086284 scopus 로고    scopus 로고
    • Naringenin-loaded nanoparticles improve the physicochemical properties and the hepatoprotective effects of naringenin in orally-administered rats with CCl(4)-induced acute liver failure
    • Yen FL, Wu TH, Lin LT, Cham TM, Lin CC. Naringenin-loaded nanoparticles improve the physicochemical properties and the hepatoprotective effects of naringenin in orally-administered rats with CCl(4)-induced acute liver failure. PharmRes. 2009;26(4):893-902.
    • (2009) PharmRes , vol.26 , Issue.4 , pp. 893-902
    • Yen, F.L.1    Wu, T.H.2    Lin, L.T.3    Cham, T.M.4    Lin, C.C.5
  • 13
    • 0141538107 scopus 로고    scopus 로고
    • Cyclooxygenase-2 biology
    • DOI 10.2174/1381612033454054
    • Clària J. Cyclooxygenase-2 biology. Curr Pharm Des. 2003;9(27):2177-2190. (Pubitemid 37139092)
    • (2003) Current Pharmaceutical Design , vol.9 , Issue.27 , pp. 2177-2190
    • Clairia, J.1
  • 14
    • 17144432482 scopus 로고
    • COX-2 inhibitors: Background knowledge for clinical use. Introduction
    • Vane JR. COX-2 inhibitors: background knowledge for clinical use. Introduction. Inflamm Res. 1988;47(suppl 2):S77.
    • (1988) Inflamm Res , vol.47 , Issue.SUPPL. 2
    • Vane, J.R.1
  • 15
    • 21744459082 scopus 로고    scopus 로고
    • The selective cyclooxygenase-2 inhibitor SC-236 reduces liver fibrosis by mechanisms involving non-parenchymal cell apoptosis and PPARgamma activation
    • DOI 10.1096/fj.04-2753fje
    • Planaguma A, Claria J, Miquel R, et al. The selective cyclooxygenase-2 inhibitor SC-236 reduces liver fibrosis by mechanisms involving non-parenchymal cell apoptosis and PPARgamma activation. FASEB J. 2005;19(9):1120-1122. (Pubitemid 40946437)
    • (2005) FASEB Journal , vol.19 , Issue.9 , pp. 1120-1122
    • Planaguma, A.1    Claria, J.2    Miquel, R.3    Lopez-Parra, M.4    Titos, E.5    Masferrer, J.L.6    Arroyo, V.7    Rodes, J.8
  • 16
    • 4744351642 scopus 로고    scopus 로고
    • Expression of HBx and COX-2 in chronic hepatitis B, cirrhosis and hepatocellular carcinoma: Implication of HBx in upregulation of COX-2
    • DOI 10.1038/modpathol.3800196
    • Cheng AS, Chan HL, Leung WK, et al. Expression of HBx and COX-2 in chronic hepatitis B, cirrhosis and hepatocellular carcinoma: implication of HBx in upregulation of COX-2. Mod Pathol. 2004;17(10):1169-1179. (Pubitemid 39312943)
    • (2004) Modern Pathology , vol.17 , Issue.10 , pp. 1169-1179
    • Cheng, A.S.-L.1    Chan, H.L.-Y.2    Leung, W.K.3    To, K.F.4    Go, M.Y.-Y.5    Chan, J.Y.-H.6    Liew, C.T.7    Sung, J.J.-Y.8
  • 17
    • 7244234090 scopus 로고    scopus 로고
    • Increased intrahepatic cyclooxygenase 2, matrix metalloproteinase 2, and matrix metalloproteinase 9 expression is associated with progressive liver disease in chronic hepatitis C virus infection: Role of viral core and NS5A proteins
    • DOI 10.1136/gut.2003.038364
    • Nunez O, Fernandez-Martinez A, Majano PL, etal. Increased intrahepatic cyclooxygenase 2, matrix metalloproteinase 2, and matrix metalloproteinase 9 expression is associated with progressive liver disease in chronic hepatitis C virus infection: role of viral core and NS5A proteins. Gut. 2004;53(11):1665- 1672. (Pubitemid 39434113)
    • (2004) Gut , vol.53 , Issue.11 , pp. 1665-1672
    • Nunez, O.1    Fernandez-Martinez, A.2    Majano, P.L.3    Apolinario, A.4    Gomez-Gonzalo, M.5    Benedicto, I.6    Lopez-Cabrera, M.7    Bosca, L.8    Clemente, G.9    Garcia-Monzon, C.10    Martin-Sanz, P.11
  • 20
    • 1842454831 scopus 로고    scopus 로고
    • Distribution of constitutive (COX-1) and inducible (COX-2) cyclooxygenase in postviral human liver cirrhosis: A possible role for COX-2 in the pathogenesis of liver cirrhosis
    • DOI 10.1136/jcp.2003.012120
    • Mohammed NA, Abd El-Aleem SA, El-Hafiz HA, McMahon RF. Distribution of constitutive (COX-1) and inducible (COX-2) cyclooxygenase in postviral human liver cirrhosis: a possible role for COX-2 in the pathogenesis of liver cirrhosis. J Clin Pathol. 2004;57(4):350-354. (Pubitemid 38446249)
    • (2004) Journal of Clinical Pathology , vol.57 , Issue.4 , pp. 350-354
    • Mohammed, N.A.1    El-Aleem, S.A.2    El-Hafiz, H.A.3    McMahon, R.F.T.4
  • 22
    • 0030665615 scopus 로고    scopus 로고
    • Dietary saturated fatty acids down-regulate cyclooxygenase-2 and tumor necrosis factor alfa and reverse fibrosis in alcohol-induced liver disease in the rat
    • Nanji AA, Zakim D, Rahemtulla A, et al. Dietary saturated fatty acids down-regulate cyclooxygenase-2 and tumor necrosis factor alfa and reverse fibrosis in alcohol-induced liver disease in the rat. Hepatol. 1997;26(6):1538-1545. (Pubitemid 27520020)
    • (1997) Hepatology , vol.26 , Issue.6 , pp. 1538-1545
    • Nanji, A.A.1    Zakim, D.2    Rahemtulla, A.3    Daly, T.4    Miao, L.5    Zhao, S.6    Khwaja, S.7    Tahan, S.R.8    Dannenberg, A.J.9
  • 23
    • 0034128995 scopus 로고    scopus 로고
    • A selective cyclooxygenase-2 inhibitor decreases proteinuria and retards progressive renal injury in rats
    • DOI 10.1046/j.1523-1755.2000.00093.x
    • Wang JL, Cheng HF, Shappell S, Harris RC. A selective cyclooxygenase-2 inhibitor decreases proteinuria and retards progressive renal injury in rats. Kidney Int. 2000;57(6):2334-2342. (Pubitemid 30340732)
    • (2000) Kidney International , vol.57 , Issue.6 , pp. 2334-2342
    • Wang, J.-L.1    Cheng, H.-F.2    Shappell, S.3    Harris, R.C.4
  • 24
    • 37849188405 scopus 로고    scopus 로고
    • Improved absorption of meloxicam via salt formation with ethanolamines
    • Han HK, Choi HK. Improved absorption of meloxicam via salt formation with ethanolamines. Eur J Pharm Biopharm. 2007; 65(1):99-103.
    • (2007) Eur J Pharm Biopharm , vol.65 , Issue.1 , pp. 99-103
    • Han, H.K.1    Choi, H.K.2
  • 25
    • 0029983724 scopus 로고    scopus 로고
    • Distinct isoforms (COX-1 and COX-2) of cyclooxygenase: Possible physiological and therapeutic implications
    • Pairet M, Engelhardt G. Distinct isoforms (COX-1 and COX-2) of cyclooxygenase: possible physiological and therapeutic implications. Fundam Clin Pharmacol. 1996;10(1):1-17.
    • (1996) Fundam Clin Pharmacol , vol.10 , Issue.1 , pp. 1-17
    • Pairet, M.1    Engelhardt, G.2
  • 26
    • 27744579858 scopus 로고    scopus 로고
    • Meloxicam: A reappraisal of pharmacokinetics, efficacy and safety
    • DOI 10.1517/14656566.6.12.2117
    • Gates BJ, Nguyen TT, Setter SM, Davies NM. Meloxicam: a reappraisal of pharmacokinetics, efficacy and safety. Expert Opin Pharmacother. 2005;6(12):2117-2140. (Pubitemid 41600587)
    • (2005) Expert Opinion on Pharmacotherapy , vol.6 , Issue.12 , pp. 2117-2140
    • Gates, B.J.1    Nguyen, T.T.2    Setter, S.M.3    Davies, N.M.4
  • 27
    • 79952131896 scopus 로고    scopus 로고
    • Meloxicam exerts neuroprotection on spinal cord trauma in rats
    • Hakan T, Toklu HZ, Biber N, et al. Meloxicam exerts neuroprotection on spinal cord trauma in rats. Int J Neurosci. 2011;121(3):142-148.
    • (2011) Int J Neurosci , vol.121 , Issue.3 , pp. 142-148
    • Hakan, T.1    Toklu, H.Z.2    Biber, N.3
  • 28
    • 79954575048 scopus 로고    scopus 로고
    • Suppressing inflammatory cascade by cyclo-oxygenase inhibitors attenuates quinolinic acid induced Huntington's disease-like alterations in rats
    • Kalonia H, Kumar A. Suppressing inflammatory cascade by cyclo-oxygenase inhibitors attenuates quinolinic acid induced Huntington's disease-like alterations in rats. Life Sci. 2011;88(17-18):784-791.
    • (2011) Life Sci , vol.88 , Issue.17-18 , pp. 784-791
    • Kalonia, H.1    Kumar, A.2
  • 29
    • 0031441558 scopus 로고    scopus 로고
    • Hepatoprotective activity of ethyl acetate extract of Acacia catechu
    • Jayasekhar P, Mohanan P, Rathinam K. Hepatoprotective activity of ethyl acetate extract of Acacia catechu. Ind J Pharmacol. 1997;29:426.
    • (1997) Ind J Pharmacol , vol.29 , pp. 426
    • Jayasekhar, P.1    Mohanan, P.2    Rathinam, K.3
  • 30
    • 76549100355 scopus 로고    scopus 로고
    • Antifibrotic effects of chronic baicalein administration in a CCl4 liver fibrosis model in rats
    • Sun H, Che QM, Zhao X, Pu XP. Antifibrotic effects of chronic baicalein administration in a CCl4 liver fibrosis model in rats. Eur J Pharmacol. 2010;631(1-3):53-60.
    • (2010) Eur J Pharmacol , vol.631 , Issue.1-3 , pp. 53-60
    • Sun, H.1    Che, Q.M.2    Zhao, X.3    Pu, X.P.4
  • 31
    • 76649098313 scopus 로고    scopus 로고
    • Protective effects of selective and non-selective cyclooxygenase inhibitors in an animal model of chronic stress
    • Kumar A, Kumari B, Kumar P. Protective effects of selective and non-selective cyclooxygenase inhibitors in an animal model of chronic stress. Neurosci Bull. 2010;26(1):17-27.
    • (2010) Neurosci Bull , vol.26 , Issue.1 , pp. 17-27
    • Kumar, A.1    Kumari, B.2    Kumar, P.3
  • 33
    • 66349129125 scopus 로고
    • A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases
    • Reitman S, Frankel S. A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. Am J Clin Pathol. 1957;28(1):56-63.
    • (1957) Am J Clin Pathol , vol.28 , Issue.1 , pp. 56-63
    • Reitman, S.1    Frankel, S.2
  • 34
    • 33746067957 scopus 로고    scopus 로고
    • Clinical laboratory, virologic, and pathologic changes in hamsters experimentally infected with pirital virus (Arenaviridae): A rodent model of Lassa fever
    • Sbrana E, Mateo RI, Xiao SY, Popov VL, Newman PC, Tesh RB. Clinical laboratory, virologic, and pathologic changes in hamsters experimentally infected with Pirital virus (Arenaviridae): a rodent model of Lassa fever. Am J Trop Med Hyg. 2006;74(6):1096-1102. (Pubitemid 351627423)
    • (2006) American Journal of Tropical Medicine and Hygiene , vol.74 , Issue.6 , pp. 1096-1102
    • Sbrana, E.1    Mateo, R.I.2    Xiao, S.-Y.3    Popov, V.L.4    Newman, P.C.5    Tesh, R.B.6
  • 35
    • 77957010110 scopus 로고
    • Isolation of liver or kidney mitochondria
    • Johnson D, Lardy H. Isolation of liver or kidney mitochondria. Methods Enzymol. 1967;10:94-96.
    • (1967) Methods Enzymol , vol.10 , pp. 94-96
    • Johnson, D.1    Lardy, H.2
  • 37
    • 0016272750 scopus 로고
    • Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase
    • Marklund S, Marklund G. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem. 1974;47(3):469-474.
    • (1974) Eur J Biochem , vol.47 , Issue.3 , pp. 469-474
    • Marklund, S.1    Marklund, G.2
  • 38
    • 0015353270 scopus 로고
    • Colorimetric assay of catalase
    • Sinha AK. Colorimetric assay of catalase. Analyt Biochem. 1972;47(2):389-394.
    • (1972) Analyt Biochem , vol.47 , Issue.2 , pp. 389-394
    • Sinha, A.K.1
  • 39
    • 0016275313 scopus 로고
    • Glutathione S-transferases. The first enzymatic step in mercapturic acid formation
    • Habig W, Pabst MJ, Jakoby W. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem. 1974;249(22):7130.
    • (1974) J Biol Chem , vol.249 , Issue.22 , pp. 7130
    • Habig, W.1    Pabst, M.J.2    Jakoby, W.3
  • 40
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • DOI 10.1016/0003-2697(79)90738-3
    • Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Analytical Biochem. 1979;95(2):351-358. (Pubitemid 9194347)
    • (1979) Analytical Biochemistry , vol.95 , Issue.2 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 41
    • 0018327389 scopus 로고
    • Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver
    • Moron MS, Depierre JW, Mannervik B. Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver. Biochim Biophys Acta. 1979;582(1):67-78. (Pubitemid 9065588)
    • (1979) Biochimica et Biophysica Acta , vol.582 , Issue.1 , pp. 67-78
    • Moron, M.S.1    Depierre, J.W.2    Mannervik, B.3
  • 42
    • 0030960657 scopus 로고    scopus 로고
    • Immunohistochemical analysis of in vivo patterns of expression of CPP32 (Caspase-3), a cell death protease
    • Krajewska M, Wang HG, Krajewski S, et al. Immunohistochemical analysis of in vivo patterns of expression of CPP32 (Caspase-3), a cell death protease. Cancer Res. 1997;57(8):1605.
    • (1997) Cancer Res , vol.57 , Issue.8 , pp. 1605
    • Krajewska, M.1    Wang, H.G.2    Krajewski, S.3
  • 43
    • 84861562656 scopus 로고    scopus 로고
    • E-Cadherin expression and p53 alterations in soft tissue sarcomas: A possible role in epithelial differentiation
    • Yoo JY, Kang SJ, Ahn WS, Kim BK. E-Cadherin expression and p53 alterations in soft tissue sarcomas: a possible role in epithelial differentiation. Cancer Res Treat. 2001;33(4):343-349.
    • (2001) Cancer Res Treat , vol.33 , Issue.4 , pp. 343-349
    • Yoo, J.Y.1    Kang, S.J.2    Ahn, W.S.3    Kim, B.K.4
  • 45
    • 13444287769 scopus 로고    scopus 로고
    • Oxidative stress mediates drug-induced hepatotoxicity in rats: A possible role of DNA fragmentation
    • DOI 10.1016/j.tox.2004.11.039
    • Amin A, Hamza AA. Oxidative stress mediates drug-induced hepatotoxicity in rats: a possible role of DNA fragmentation. Toxicol. 2005;208(3):367-375. (Pubitemid 40202835)
    • (2005) Toxicology , vol.208 , Issue.3 , pp. 367-375
    • Amin, A.1    Hamza, A.A.2
  • 46
    • 0036591855 scopus 로고    scopus 로고
    • Free radical-induced damage to DNA: Mechanisms and measurement
    • DOI 10.1016/S0891-5849(02)00826-2, PII S0891584902008262
    • Dizdaroglu M, Jaruga P, Birincioglu M, Rodriguez H. Free radical-induced damage to DNA: mechanisms and measurement. Free Radic Biol Med. 2002;32(11):1102-1115. (Pubitemid 34603348)
    • (2002) Free Radical Biology and Medicine , vol.32 , Issue.11 , pp. 1102-1115
    • Dizdaroglu, M.1    Jaruga, P.2    Birincioglu, M.3    Rodriguez, H.4
  • 50
    • 77957124603 scopus 로고    scopus 로고
    • Antifibrotic and fibrolytic properties of celecoxib in liver damage induced by carbon tetrachloride in the rat
    • Chávez E, Segovia J, Shibayama M, et al. Antifibrotic and fibrolytic properties of celecoxib in liver damage induced by carbon tetrachloride in the rat. Liver Int. 2010;30(7):969-978.
    • (2010) Liver Int , vol.30 , Issue.7 , pp. 969-978
    • Chávez, E.1    Segovia, J.2    Shibayama, M.3
  • 51
    • 77950904899 scopus 로고    scopus 로고
    • Effect of celecoxib, a selective cyclooxygenase-2 inhibitor on carbon tetrachloride intoxication in rats
    • Washino Y, Koga E, Kitamura Y, et al. Effect of celecoxib, a selective cyclooxygenase-2 inhibitor on carbon tetrachloride intoxication in rats. Biol Pharm Bull. 2010;33(4):707-709.
    • (2010) Biol Pharm Bull , vol.33 , Issue.4 , pp. 707-709
    • Washino, Y.1    Koga, E.2    Kitamura, Y.3
  • 52
    • 33645963118 scopus 로고    scopus 로고
    • COX 2 induction in mice with experimental nutritional steatohepatitis: Role as pro inflammatory mediator
    • Yu J, Ip E. COX 2 induction in mice with experimental nutritional steatohepatitis: role as pro inflammatory mediator. Hepatol. 2006;43(4):826-836.
    • (2006) Hepatol , vol.43 , Issue.4 , pp. 826-836
    • Yu, J.1    Ip, E.2
  • 60
  • 61
    • 0037436437 scopus 로고    scopus 로고
    • Role of oxidative stress and mitochondrial changes in cyanobacteria induced apoptosis and hepatotoxicity
    • Ding WX, Ong NC. Role of oxidative stress and mitochondrial changes in cyanobacteria induced apoptosis and hepatotoxicity. FEMS Microbiol Lett. 2003;220(1):1-7.
    • (2003) FEMS Microbiol Lett , vol.220 , Issue.1 , pp. 1-7
    • Ding, W.X.1    Ong, N.C.2
  • 62
    • 0033898886 scopus 로고    scopus 로고
    • 2+ homeostasis
    • DOI 10.1016/S0168-0102(00)00124-3, PII S0168010200001243
    • Pereira CF, Oliveira CR. Oxidative glutamate toxicity involves mitochondrial dysfunction and perturbation of intracellular Ca2+homeostasis. Neurosci Res. 2000;37(3):227-236. (Pubitemid 30625012)
    • (2000) Neuroscience Research , vol.37 , Issue.3 , pp. 227-236
    • Pereira, C.F.1    Oliveira, C.R.D.2
  • 63
    • 0031876158 scopus 로고    scopus 로고
    • Evidence of hepatocyte apoptosis in rat liver after the administration of carbon tetrachloride
    • Shi J, Aisaki K, Ikawa Y, Wake K. Evidence of hepatocyte apoptosis in rat liver after the administration of carbon tetrachloride. Am J Pathol. 1998;153(2):515-525. (Pubitemid 28373662)
    • (1998) American Journal of Pathology , vol.153 , Issue.2 , pp. 515-525
    • Shi, J.1    Aisaki, K.2    Ikawa, Y.3    Wake, K.4
  • 64
    • 0036257307 scopus 로고    scopus 로고
    • Biochemical and cellular mechanisms of toxic liver injury
    • DOI 10.1055/s-2002-30100
    • Kaplowitz N. Biochemical and cellular mechanisms of toxic liver injury. Semin Liver Dis. 2002;22(2):137-44. (Pubitemid 34496467)
    • (2002) Seminars in Liver Disease , vol.22 , Issue.2 , pp. 137-144
    • Kaplowitz, N.1
  • 66
    • 0035884041 scopus 로고    scopus 로고
    • Differential protection with inhibitors of caspase-8 and caspase-3 in murine models of tumor necrosis factor and fas receptor-mediated hepatocellular apoptosis
    • DOI 10.1006/taap.2001.9242
    • Bajt ML, Vonderfecht SL, Jaeschke H. Differential protection with inhibitors of caspase-8 and caspase-3 in murine models of tumor necrosis factor and Fas receptor-mediated hepatocellular apoptosis. Toxicol Appl Pharmacol. 2001;175(3):243-252. (Pubitemid 32917748)
    • (2001) Toxicology and Applied Pharmacology , vol.175 , Issue.3 , pp. 243-252
    • Bajt, M.L.1    Vonderfecht, S.L.2    Jaeschke, H.3
  • 67
    • 21044445452 scopus 로고    scopus 로고
    • Apoptosis: A mechanism of acute and chronic liver injury
    • DOI 10.1136/gut.2004.053850
    • Guicciardi M, Gores G. Apoptosis: a mechanism of acute and chronic liver injury. Gut. 2005;54(7):1024-1033. (Pubitemid 40873921)
    • (2005) Gut , vol.54 , Issue.7 , pp. 1024-1033
    • Guicciardi, M.E.1    Gores, G.J.2
  • 69
    • 47649128226 scopus 로고    scopus 로고
    • Effect of selective cyclooxygenase-2 inhibitor meloxicam on liver fibrosis in rats with ligated common bile ducts
    • DOI 10.1111/j.1872-034X.2008.00339.x
    • Kim SM, Park KC, Kim HG, Han SJ. Effect of selective cyclooxygenase 2 inhibitor meloxicam on liver fibrosis in rats with ligated common bile ducts. Hepatol Res. 2008;38(8):800-809. (Pubitemid 352015631)
    • (2008) Hepatology Research , vol.38 , Issue.8 , pp. 800-809
    • Kim, S.M.1    Park, K.C.2    Kim, H.G.3    Han, S.J.4
  • 70
    • 79955651827 scopus 로고    scopus 로고
    • Hepatoprotective and antioxidant effects of porcine plasma protein hydrolysates on carbon tetrachloride-induced liver damage in rats
    • Liu Q, Kong B, Li G, Liu N, Xia X. Hepatoprotective and antioxidant effects of porcine plasma protein hydrolysates on carbon tetrachloride-induced liver damage in rats. Food Chem Toxicol. 2011;49(6):1316-1321.
    • (2011) Food Chem Toxicol , vol.49 , Issue.6 , pp. 1316-1321
    • Liu, Q.1    Kong, B.2    Li, G.3    Liu, N.4    Xia, X.5
  • 71
    • 77955711643 scopus 로고    scopus 로고
    • Renal tissue damage after experimental pyelonephritis: Role of anti-oxidants and selective cyclooxygenase-2 inhibitors
    • Gurocak S, Ure I, Cumaoglu A, et al. Renal tissue damage after experimental pyelonephritis: role of anti-oxidants and selective cyclooxygenase-2 inhibitors. Urology. 2010;76(2):508.e1-508.e5.
    • (2010) Urology , vol.76 , Issue.2
    • Gurocak, S.1    Ure, I.2    Cumaoglu, A.3
  • 72
    • 0042134696 scopus 로고    scopus 로고
    • In vivo effects of meloxicam, celecoxib, and ibuprofen on free radical metabolism in human erythrocytes
    • DOI 10.1081/DCT-120022645
    • Cimen BM, Cimen BÖ, Eskandari G, Sahin G, Erdogan C, Atik U. In vivo effects of meloxicam, celecoxib, and ibuprofen on free radical metabolism in human erythrocytes. Drug chem Toxicol. 2003;26(3):169-176. (Pubitemid 36951088)
    • (2003) Drug and Chemical Toxicology , vol.26 , Issue.3 , pp. 169-176
    • Cimen, M.Y.B.1    Cimen, O.B.2    Eskandari, G.3    Sahin, G.4    Erdogan, C.5    Atik, U.6
  • 74
    • 26844522332 scopus 로고    scopus 로고
    • 2 through enhancement of NF- B activity in lipopolysaccharide-activated human primary monocytes
    • Lu Y,Wahl LM. Oxidative stress augments the production ofmatrix metalloproteinase-1, cyclooxygenase-2, and prostaglandin E2 through enhancement of NF- B activity in lipopolysaccharide-activated human primary monocytes. J Immunol. 2005;175(8):5423-5429. (Pubitemid 41456428)
    • (2005) Journal of Immunology , vol.175 , Issue.8 , pp. 5423-5429
    • Lu, Y.1    Wahl, L.M.2
  • 75
    • 0028860983 scopus 로고
    • Anti-inflammatory, analgesic, antipyretic and related properties of meloxicam, a new non-steroidal anti-inflammatory agent with favourable gastrointestinal tolerance
    • Engelhardt G, Homma D, Schlegel K, Utzmann R, Schnitzler C. Anti-inflammatory, analgesic, antipyretic and related properties of meloxicam, a new non-steroidal anti-inflammatory agent with favourable gastrointestinal tolerance. Inflam Res. 1995;44(10):423-433.
    • (1995) Inflam Res , vol.44 , Issue.10 , pp. 423-433
    • Engelhardt, G.1    Homma, D.2    Schlegel, K.3    Utzmann, R.4    Schnitzler, C.5
  • 76
    • 0033919727 scopus 로고    scopus 로고
    • Apoptosis, anoikis and their relevance to the pathobiology of colon cancer
    • DOI 10.1046/j.1440-1827.2000.01047.x
    • Shanmugathasan M, Jothy S. Apoptosis, anoikis and their relevance to the pathobiology of colon cancer. Pathol Int. 2000;50(4):273-279. (Pubitemid 30441278)
    • (2000) Pathology International , vol.50 , Issue.4 , pp. 273-279
    • Shanmugathasan, M.1    Jothy, S.2
  • 77
    • 0036022402 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: An update
    • DOI 10.1023/A:1016119328968
    • Soldani C, Scovassi AI. Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: an update. Apoptosis. 2002;7(4):321-328. (Pubitemid 34832256)
    • (2002) Apoptosis , vol.7 , Issue.4 , pp. 321-328
    • Soldani, C.1    Scovassi, A.I.2
  • 78
    • 41549163847 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2 aggravates secretory phospholipaseA2- mediated progression of acute liver injury
    • Bhave VS, Donthamsetty S, Latendresse JR, Mehendale HM. Inhibition of cyclooxygenase-2 aggravates secretory phospholipaseA2-mediated progression of acute liver injury. Toxicol Appl Pharmacol. 2008;228(2):239-246.
    • (2008) Toxicol Appl Pharmacol , vol.228 , Issue.2 , pp. 239-246
    • Bhave, V.S.1    Donthamsetty, S.2    Latendresse, J.R.3    Mehendale, H.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.