Selective hyper-responsiveness of the interferon system in major depressive disorders and depression induced by interferon therapy

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Schlaak, Joerg F ^a   Trippler, Martin ^a   Hoyo Becerra, Carolina ^a   Erim, Yesim ^b   Kis, Bernhard ^c   Wang, Bo ^a   Scherbaum, Norbert ^c   Gerken, Guido ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

^b Rheinische Kliniken   (Germany)

^c UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; PEGINTERFERON ALPHA2A; RIBAVIRIN; ALPHA INTERFERON; ALPHA2A INTERFERON; PRIMER DNA; RECOMBINANT PROTEIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DEPRESSION; DISEASE SEVERITY; FEMALE; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; HEPATITIS C; HUMAN; HUMAN CELL; IN VITRO STUDY; MAJOR DEPRESSION; MALE; NERVE CELL DIFFERENTIATION; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; TREATMENT RESPONSE; UPREGULATION; VALIDATION PROCESS; CASE CONTROL STUDY; CHEMICALLY INDUCED DISORDER; CLINICAL TRIAL; DRUG EFFECT; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; MICROARRAY ANALYSIS; MIDDLE AGED; MONONUCLEAR CELL; NONPARAMETRIC TEST; PROSPECTIVE STUDY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; CASE-CONTROL STUDIES; DEPRESSIVE DISORDER, MAJOR; DNA PRIMERS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HEPATITIS C, CHRONIC; HUMANS; INTERFERON-ALPHA; LEUKOCYTES, MONONUCLEAR; MALE; MICROARRAY ANALYSIS; MIDDLE AGED; PROSPECTIVE STUDIES; REAL-TIME POLYMERASE CHAIN REACTION; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STATISTICS, NONPARAMETRIC;

EID: 84862004123     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038668     Document Type: Article

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