JBP1 and JBP2 proteins are Fe2+/2-oxoglutarate-dependent dioxygenases regulating hydroxylation of thymidine residues in trypanosome DNA

Journal of Biological Chemistry

Volumn 287, Issue 24, 2012, Pages 19886-19895

  Cliffe, Laura J ^a   Hirsch, Gwen ^a   Wang, Jin ^b   Ekanayake, Dilrukshi ^a   Bullard, Whitney ^a   Hu, Muhan ^a   Wang, Yinsheng ^b   Sabatini, Robert ^a  

^a Davidson Life Science Bldg ^*  (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANAEROBIC CONDITIONS; DIOXYGENASES; GLUCOSYLATION; HYDROXYLASE ACTIVITY; HYDROXYLASES; HYPOXIC CONDITION; IN-VITRO; IN-VIVO; IN-VIVO ANALYSIS; IRON BINDING; METAL CHELATION; N-TERMINALS; O-LINKED; OXIDATIVE DECARBOXYLATION; PARASITE-; POLYMERASE II TRANSCRIPTION; SPECTROSCOPIC SIGNATURES; SYNTHESIS MODELS;

BIOCHEMISTRY; CARBON DIOXIDE; CARBOXYLATION; GENE EXPRESSION; HYDROXYLATION; PROTEINS;

BIOSYNTHESIS;

PROTEIN JBP1; PROTEIN JBP2; PROTOZOAL DNA; PROTOZOAL PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DECARBOXYLATION; DNA REPLICATION; ENZYME ACTIVITY; ENZYME REGULATION; EPIMASTIGOTE; GENE EXPRESSION REGULATION; HYDROXYLATION; IMMUNOBLOTTING; IN VITRO STUDY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; NONHUMAN; PARASITE VIRULENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MODIFICATION; SEQUENCE HOMOLOGY; SPECTROSCOPY; TANDEM MASS SPECTROMETRY; TRYPANOSOMA BRUCEI;

DIOXYGENASES; DNA, PROTOZOAN; DNA-BINDING PROTEINS; HYDROXYLATION; IRON; PROTOZOAN PROTEINS; THYMIDINE; TRYPANOSOMA CRUZI;

EID: 84862001094     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.341974     Document Type: Article

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