Rapid affinity measurement of protein-protein interactions in a microfluidic platform

Analytical Biochemistry

Volumn 426, Issue 2, 2012, Pages 134-141

  Salimi Moosavi, Hossein ^a   Rathanaswami, Palaniswami ^a   Rajendran, Surendran ^a   Toupikov, Mike ^a   Hill, John ^b  

^a AMGEN INC   (United States)

^b AMGEN INC   (United States)

Author keywords

Antigen antibody binding; Binding affinity; Equilibrium binding constant; Equilibrium dissociation constant; Gyrolab; GYROS; KinExA; Rapid affinity ranking

Indexed keywords

ANTIGENS; BINDING ENERGY; DISSOCIATION; MAMMALS; MICROFLUIDICS;

ANTIGEN-ANTIBODY BINDING; BINDING AFFINITIES; EQUILIBRIUM BINDING CONSTANT; EQUILIBRIUM DISSOCIATION CONSTANT; GYROLAB; GYROS; KINEXA; RAPID AFFINITY RANKING;

ANTIBODIES;

BOVINE SERUM ALBUMIN; DIGOXIN; MONOCLONAL ANTIBODY;

ALGORITHM; ANTIBODY COMBINING SITE; ANTIBODY TITER; ANTIGEN ANTIBODY COMPLEX; ARTICLE; BINDING AFFINITY; CHEMICAL REACTION; CONCENTRATION (PARAMETERS); IMMUNOREACTIVITY; INHIBITION KINETICS; MEASUREMENT; MICROFLUIDICS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION;

BOVINAE;

EID: 84861999221     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2012.04.023     Document Type: Article

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