-
1
-
-
77955923386
-
Molecular therapy of breast cancer: progress and future directions
-
Lin SX, Chen J, Mazumdar M, Poirier D, Wang C, et al. (2010) Molecular therapy of breast cancer: progress and future directions. Nat Rev Endocrinol 6 (9): 485-493.
-
(2010)
Nat Rev Endocrinol
, vol.6
, Issue.9
, pp. 485-493
-
-
Lin, S.X.1
Chen, J.2
Mazumdar, M.3
Poirier, D.4
Wang, C.5
-
2
-
-
79959605526
-
-
American Cancer Society., (online), available:. asp, accessed Dec 5
-
American Cancer Society. What are the key statistics about lung cancer (online), available:http://www.cancer.org/docroot/cri/content/cri_2_4_1x_what_are_the_key_Statistics_about_lung_cancer_15. asp, accessed 2009 Dec 5.
-
(2009)
What are the key statistics about lung cancer
-
-
-
3
-
-
77949561690
-
-
American Cancer Society., (online), available:, accessed Dec 5
-
American Cancer Society. Breast cancer facts and figures 2009-2010 (online), available: http://www.cancer.org/downloads/STT/F861009_final%209-08-09.pdf., accessed 2009 Dec 5.
-
(2009)
Breast cancer facts and figures 2009-2010
-
-
-
4
-
-
29144521213
-
Sex steroid-producing enzymes in human breast cancer
-
Suzuki T, Miki Y, Nakamura Y, Moriya T, Ito K, et al. (2005) Sex steroid-producing enzymes in human breast cancer. Endocr Relat Cancer 12 (4): 701-720.
-
(2005)
Endocr Relat Cancer
, vol.12
, Issue.4
, pp. 701-720
-
-
Suzuki, T.1
Miki, Y.2
Nakamura, Y.3
Moriya, T.4
Ito, K.5
-
5
-
-
63649099281
-
Novel actions of estrogen to promote proliferation: Integration of cytoplasmic and nuclear pathways
-
Fox EM, Andrade J, Shupnik MA, (2009) Novel actions of estrogen to promote proliferation: Integration of cytoplasmic and nuclear pathways. Steroids 74 (7): 622-627.
-
(2009)
Steroids
, vol.74
, Issue.7
, pp. 622-627
-
-
Fox, E.M.1
Andrade, J.2
Shupnik, M.A.3
-
6
-
-
0035529054
-
Abnormal expression of 17beta-hydroxysteroid dehydrogenases in breast cancer predicts late recurrence
-
Gunnarsson C, Olsson BM, Stål O, (2001) Abnormal expression of 17beta-hydroxysteroid dehydrogenases in breast cancer predicts late recurrence. Cancer Res 61 (23): 8448-8451.
-
(2001)
Cancer Res
, vol.61
, Issue.23
, pp. 8448-8451
-
-
Gunnarsson, C.1
Olsson, B.M.2
Stål, O.3
-
7
-
-
77950421854
-
17β-hydroxysteroid dehydrogenase type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production
-
Aka JA, Mazumdar M, Chen CQ, Poirier D, Lin SX, (2010) 17β-hydroxysteroid dehydrogenase type 1 stimulates breast cancer by dihydrotestosterone inactivation in addition to estradiol production. Mol Endocrinol 24 (4): 832-845.
-
(2010)
Mol Endocrinol
, vol.24
, Issue.4
, pp. 832-845
-
-
Aka, J.A.1
Mazumdar, M.2
Chen, C.Q.3
Poirier, D.4
Lin, S.X.5
-
8
-
-
0035546023
-
Involvement of up-regulation of 17β-hydroxysteroid dehydrogenase type 1 in maintenance of intratumoral high estradiol levels in postmenopausal breast cancers
-
Miyoshi Y, Ando A, Shiba E, Taguchi T, Tamaki Y, et al. (2001) Involvement of up-regulation of 17β-hydroxysteroid dehydrogenase type 1 in maintenance of intratumoral high estradiol levels in postmenopausal breast cancers. Int J Cancer 94 (5): 685-689.
-
(2001)
Int J Cancer
, vol.94
, Issue.5
, pp. 685-689
-
-
Miyoshi, Y.1
Ando, A.2
Shiba, E.3
Taguchi, T.4
Tamaki, Y.5
-
9
-
-
66149186856
-
Ratio of 17HSD1 to 17HSD2 protein expression predicts the outcome of tamoxifen treatment in postmenopausal breast cancer patients
-
Jansson A, Delander L, Gunnarsson C, Fornander T, Skoog L, et al. (2009) Ratio of 17HSD1 to 17HSD2 protein expression predicts the outcome of tamoxifen treatment in postmenopausal breast cancer patients. Clin Cancer Res 15 (10): 3610-3616.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.10
, pp. 3610-3616
-
-
Jansson, A.1
Delander, L.2
Gunnarsson, C.3
Fornander, T.4
Skoog, L.5
-
10
-
-
61649096847
-
Perspectives in understanding the role of human 17β-hydroxysteroid dehydrogenases in health and disease
-
Meier M, Möller G, Adamski J, (2009) Perspectives in understanding the role of human 17β-hydroxysteroid dehydrogenases in health and disease. Ann N Y Acad Sci 1155 (1): 15-24.
-
(2009)
Ann N Y Acad Sci
, vol.1155
, Issue.1
, pp. 15-24
-
-
Meier, M.1
Möller, G.2
Adamski, J.3
-
11
-
-
60249089957
-
Integrated view on 17beta-hydroxysteroid dehydrogenases
-
Moeller G, Adamski J, (2009) Integrated view on 17beta-hydroxysteroid dehydrogenases. Mol Cell Endocrinol 301 (1-2): 7-19.
-
(2009)
Mol Cell Endocrinol
, vol.301
, Issue.1-2
, pp. 7-19
-
-
Moeller, G.1
Adamski, J.2
-
12
-
-
62949206264
-
17beta-hydroxysteroid dehydrogenase enzymes and breast cancer
-
Jansson A, (2009) 17beta-hydroxysteroid dehydrogenase enzymes and breast cancer. J Steroid Biochem Mol Biol 114 (1-2): 64-67.
-
(2009)
J Steroid Biochem Mol Biol
, vol.114
, Issue.1-2
, pp. 64-67
-
-
Jansson, A.1
-
13
-
-
0032586817
-
17beta-hydroxysteroid dehydrogenase (HSD)/17-ketosteroid reductase (KSR) family; nomenclature and main characteristics of the 17HSD/KSR enzymes
-
Peltoketo H, Luu-The V, Simard J, Adamski J, (1999) 17beta-hydroxysteroid dehydrogenase (HSD)/17-ketosteroid reductase (KSR) family; nomenclature and main characteristics of the 17HSD/KSR enzymes. J Mol Endocrinol 23 (1): 1-11.
-
(1999)
J Mol Endocrinol
, vol.23
, Issue.1
, pp. 1-11
-
-
Peltoketo, H.1
Luu-The, V.2
Simard, J.3
Adamski, J.4
-
14
-
-
0033532388
-
Human estrogenic 17beta-hydroxysteroid dehydrogenase: predominance of estrone reduction and its induction by NADPH
-
Jin JZ, Lin SX, (1999) Human estrogenic 17beta-hydroxysteroid dehydrogenase: predominance of estrone reduction and its induction by NADPH. Biochem Biophys Res Commun 259 (2): 489-493.
-
(1999)
Biochem Biophys Res Commun
, vol.259
, Issue.2
, pp. 489-493
-
-
Jin, J.Z.1
Lin, S.X.2
-
15
-
-
0037151061
-
Purification, reconstitution, and steady-state kinetics of the trans-membrane 17beta -hydroxysteroid dehydrogenase 2
-
Lu ML, Huang YW, Lin SX, (2002) Purification, reconstitution, and steady-state kinetics of the trans-membrane 17beta-hydroxysteroid dehydrogenase 2. J Biol Chem 277 (25): 22123-22130.
-
(2002)
J Biol Chem
, vol.277
, Issue.25
, pp. 22123-22130
-
-
Lu, M.L.1
Huang, Y.W.2
Lin, S.X.3
-
16
-
-
69249127192
-
Biochemical factors governing the steady-state estrone/estradiol ratios catalyzed by human 17beta-hydroxysteroid dehydrogenases types 1 and 2 in HEK-293 Cells
-
Sherbet DP, Guryev OL, Papari-Zareei M, Mizrachi D, Rambally S, et al. (2009) Biochemical factors governing the steady-state estrone/estradiol ratios catalyzed by human 17beta-hydroxysteroid dehydrogenases types 1 and 2 in HEK-293 Cells. Endocrinology 150 (9): 4154-4162.
-
(2009)
Endocrinology
, vol.150
, Issue.9
, pp. 4154-4162
-
-
Sherbet, D.P.1
Guryev, O.L.2
Papari-Zareei, M.3
Mizrachi, D.4
Rambally, S.5
-
17
-
-
0029670229
-
Human 17 beta-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell- and tissue-specific expression
-
Miettinen MM, Mustonen MV, Poutanen MH, Isomaa VV, Vihko RK, (1996) Human 17 beta-hydroxysteroid dehydrogenase type 1 and type 2 isoenzymes have opposite activities in cultured cells and characteristic cell- and tissue-specific expression. Biochem J 314: 839-845.
-
(1996)
Biochem J
, vol.314
, pp. 839-845
-
-
Miettinen, M.M.1
Mustonen, M.V.2
Poutanen, M.H.3
Isomaa, V.V.4
Vihko, R.K.5
-
18
-
-
60249090183
-
Relative involvement of three 17beta-hydroxysteroid dehydrogenases (types 1, 7 and 12) in the formation of estradiol in various breast cancer cell lines using selective inhibitors
-
Laplante Y, Rancourt C, Poirier D, (2009) Relative involvement of three 17beta-hydroxysteroid dehydrogenases (types 1, 7 and 12) in the formation of estradiol in various breast cancer cell lines using selective inhibitors. Mol Cell Endocrinol 301 (1-2): 146-153.
-
(2009)
Mol Cell Endocrinol
, vol.301
, Issue.1-2
, pp. 146-153
-
-
Laplante, Y.1
Rancourt, C.2
Poirier, D.3
-
19
-
-
33751100414
-
Proliferative responses to altered 17beta-hydroxysteroid dehydrogenase (17HSD) type 2 expression in human breast cancer cells are dependent on endogenous expression of 17HSD type 1 and the oestradiol receptors
-
Jansson A, Gunnarsson C, Stål O, (2006) Proliferative responses to altered 17beta-hydroxysteroid dehydrogenase (17HSD) type 2 expression in human breast cancer cells are dependent on endogenous expression of 17HSD type 1 and the oestradiol receptors. Endocr Relat Cancer 13 (3): 875-884.
-
(2006)
Endocr Relat Cancer
, vol.13
, Issue.3
, pp. 875-884
-
-
Jansson, A.1
Gunnarsson, C.2
Stål, O.3
-
20
-
-
3543068881
-
Human 17beta-hydroxysteroid dehydrogenases types 1, 2, and 3 catalyze bi-directional equilibrium reactions, rather than unidirectional metabolism, in HEK-293 cells
-
Khan N, Sharma KK, Andersson S, Auchus RJ, (2004) Human 17beta-hydroxysteroid dehydrogenases types 1, 2, and 3 catalyze bi-directional equilibrium reactions, rather than unidirectional metabolism, in HEK-293 cells. Arch Biochem Biophys 429 (1): 50-59.
-
(2004)
Arch Biochem Biophys
, vol.429
, Issue.1
, pp. 50-59
-
-
Khan, N.1
Sharma, K.K.2
Andersson, S.3
Auchus, R.J.4
-
21
-
-
75749134031
-
A genome-wide perspective of genetic variation in human metabolism
-
Illig T, Gieger C, Zhai GJ, Margl WR, Sattler RW, et al. (2010) A genome-wide perspective of genetic variation in human metabolism. Nat Genet 42 (2): 137-141.
-
(2010)
Nat Genet
, vol.42
, Issue.2
, pp. 137-141
-
-
Illig, T.1
Gieger, C.2
Zhai, G.J.3
Margl, W.R.4
Sattler, R.W.5
-
22
-
-
59049106039
-
Expression of 17beta-hydroxysteroid dehydrogenases and other estrogen-metabolizing enzymes in different cancer cell lines
-
Smuc T, Rizner TL, (2009) Expression of 17beta-hydroxysteroid dehydrogenases and other estrogen-metabolizing enzymes in different cancer cell lines. Chem Biol Interact 178 (1-3): 228-233.
-
(2009)
Chem Biol Interact
, vol.178
, Issue.1-3
, pp. 228-233
-
-
Smuc, T.1
Rizner, T.L.2
-
23
-
-
0035872216
-
Human oestrogenic 17beta-hydroxysteroid dehydrogenase specificity: enzyme regulation through an NADPH-dependent substrate inhibition towards the highly specific oestrone reduction
-
Gangloff A, Garneau A, Huang YW, Yang F, Lin SX, (2001) Human oestrogenic 17beta-hydroxysteroid dehydrogenase specificity: enzyme regulation through an NADPH-dependent substrate inhibition towards the highly specific oestrone reduction. Biochem J 356: 269-276.
-
(2001)
Biochem J
, vol.356
, pp. 269-276
-
-
Gangloff, A.1
Garneau, A.2
Huang, Y.W.3
Yang, F.4
Lin, S.X.5
-
24
-
-
0029045633
-
Estrone sulfate-sulfatase and 17[beta]-hydroxysteroid dehydrogenase activities: a hypothesis for their role in the evolution of human breast cancer from hormone-dependence to hormone-independence
-
Pasqualini JR, Chetrite G, Nguyen BL, Maloche C, Delalonde L, et al. (1995) Estrone sulfate-sulfatase and 17[beta]-hydroxysteroid dehydrogenase activities: a hypothesis for their role in the evolution of human breast cancer from hormone-dependence to hormone-independence. J Steroid Biochem Mol Biol 53 (1-6): 407-412.
-
(1995)
J Steroid Biochem Mol Biol
, vol.53
, Issue.1-6
, pp. 407-412
-
-
Pasqualini, J.R.1
Chetrite, G.2
Nguyen, B.L.3
Maloche, C.4
Delalonde, L.5
-
25
-
-
0029872530
-
Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre- and postmenopausal breast cancer patients
-
Pasqualini JR, Chetrite G, Blacker C, Feinstein MC, Delalonde L, et al. (1996) Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre- and postmenopausal breast cancer patients. J Clin Endocrinol Metab 81 (4): 1460-1464.
-
(1996)
J Clin Endocrinol Metab
, vol.81
, Issue.4
, pp. 1460-1464
-
-
Pasqualini, J.R.1
Chetrite, G.2
Blacker, C.3
Feinstein, M.C.4
Delalonde, L.5
-
26
-
-
77954243044
-
Cell proliferation regulated by estradiol receptor: Therapeutic implications
-
Castoria G, Migliaccio A, Giovannelli P, Auricchio F, (2010) Cell proliferation regulated by estradiol receptor: Therapeutic implications. Steroids 75 (8-9): 524-527.
-
(2010)
Steroids
, vol.75
, Issue.8-9
, pp. 524-527
-
-
Castoria, G.1
Migliaccio, A.2
Giovannelli, P.3
Auricchio, F.4
-
27
-
-
23844485897
-
From the cover: location analysis of estrogen receptor alpha target promoters reveals that FOXA1 defines a domain of the estrogen response
-
Laganière J, Deblois G, Lefebvre C, Bataille AR, Robert F, (2005) From the cover: location analysis of estrogen receptor alpha target promoters reveals that FOXA1 defines a domain of the estrogen response. Proc Natl Acad Sci USA 102 (33): 11651-11656.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.33
, pp. 11651-11656
-
-
Laganière, J.1
Deblois, G.2
Lefebvre, C.3
Bataille, A.R.4
Robert, F.5
-
28
-
-
3543002856
-
Estrogens and progesterone promote persistent CCND1 gene activation during G1 by inducing transcriptional derepression via c-Jun/c-Fos/estrogen receptor (progesterone receptor) complex assembly to a distal regulatory element and recruitment of Cyclin D1 to its own gene promoter
-
Cicatiello L, Addeo R, Sasso A, Altucci L, Petrizzi VB, (2004) Estrogens and progesterone promote persistent CCND1 gene activation during G1 by inducing transcriptional derepression via c-Jun/c-Fos/estrogen receptor (progesterone receptor) complex assembly to a distal regulatory element and recruitment of Cyclin D1 to its own gene promoter. Mol Cell Biol 24 (16): 7260-7274.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.16
, pp. 7260-7274
-
-
Cicatiello, L.1
Addeo, R.2
Sasso, A.3
Altucci, L.4
Petrizzi, V.B.5
-
29
-
-
0023691704
-
Complete amino acid sequence of human placental 17beta-hydroxysteroid dehydrogenase deduced from cDNA
-
Peltoketo H, Isomaa V, Mäentausta O, Vihko R, (1988) Complete amino acid sequence of human placental 17beta-hydroxysteroid dehydrogenase deduced from cDNA. FEBS Letters 239 (1): 73-77.
-
(1988)
FEBS Letters
, vol.239
, Issue.1
, pp. 73-77
-
-
Peltoketo, H.1
Isomaa, V.2
Mäentausta, O.3
Vihko, R.4
-
30
-
-
0027225486
-
Expression cloning and characterization of human 17 beta-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activity
-
Wu L, Einstein M, Geissler WM, Chan HK, Elliston KO, et al. (1993) Expression cloning and characterization of human 17 beta-hydroxysteroid dehydrogenase type 2, a microsomal enzyme possessing 20 alpha-hydroxysteroid dehydrogenase activity. J Biol Chem 268 (17): 12964-12969.
-
(1993)
J Biol Chem
, vol.268
, Issue.17
, pp. 12964-12969
-
-
Wu, L.1
Einstein, M.2
Geissler, W.M.3
Chan, H.K.4
Elliston, K.O.5
-
31
-
-
60249089307
-
Reductive 17beta-hydroxysteroid dehydrogenases in the sulfatase pathway: Critical in the cell proliferation of breast cancer
-
Aka JA, Mazumdar M, Lin SX, (2009) Reductive 17beta-hydroxysteroid dehydrogenases in the sulfatase pathway: Critical in the cell proliferation of breast cancer. Mol Cell Endocrinol 301 (1-2): 183-190.
-
(2009)
Mol Cell Endocrinol
, vol.301
, Issue.1-2
, pp. 183-190
-
-
Aka, J.A.1
Mazumdar, M.2
Lin, S.X.3
|