메뉴 건너뛰기




Volumn 10, Issue 4, 2010, Pages 281-286

Application of electroporation in DNA vaccination protocols

Author keywords

Cancer vaccines; DNA vaccines; Electroporation; Gene therapy

Indexed keywords

CANCER VACCINE; DNA VACCINE; HUMAN IMMUNODEFICIENCY VIRUS VACCINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NONSTRUCTURAL PROTEIN 3; NONSTRUCTURAL PROTEIN 5B; PLASMID DNA; PROSTATE SPECIFIC ANTIGEN; PROSTATE STEM CELL ANTIGEN; PROTEIN E6; PROTEIN E7;

EID: 77958026029     PISSN: 15665232     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652310791823506     Document Type: Article
Times cited : (35)

References (61)
  • 1
    • 20644433088 scopus 로고    scopus 로고
    • Immunobiology of muscle:Advances in understanding an immunological microenvironment
    • Wiendl H, Hohlfeld R, Kieseier BC. Immunobiology of muscle:advances in understanding an immunological microenvironment. Trends Immunol 2005; 26: 373-80.
    • (2005) Trends Immunol , vol.26 , pp. 373-380
    • Wiendl, H.1    Hohlfeld, R.2    Kieseier, B.C.3
  • 2
    • 0035137604 scopus 로고    scopus 로고
    • Cp Gmotifs of DNA vaccines induce the expression of chemokines andMHC class II molecules on myocytes
    • Stan AC, Casares S, Brumeanu TD, Klinman DM, Bona CA. Cp Gmotifs of DNA vaccines induce the expression of chemokines andMHC class II molecules on myocytes. Eur J Immunol 2001; 31: 301-10.
    • (2001) Eur J Immunol , vol.31 , pp. 301-310
    • Stan, A.C.1    Casares, S.2    Brumeanu, T.D.3    Klinman, D.M.4    Bona, C.A.5
  • 3
    • 34250843124 scopus 로고    scopus 로고
    • Potential of transfectedmuscle cells to contribute to DNA vaccine immunogenicity
    • Shirota H, Petrenko L, Hong C, Klinman DM. Potential of transfectedmuscle cells to contribute to DNA vaccine immunogenicity. J Immunol 2007; 179: 329-36.
    • (2007) J Immunol , vol.179 , pp. 329-336
    • Shirota, H.1    Petrenko, L.2    Hong, C.3    Klinman, D.M.4
  • 5
    • 0035423441 scopus 로고    scopus 로고
    • DNA fusion vaccinedesigned to induce cytotoxic T cell responses against defined peptidemotifs: Implications for cancer vaccines
    • Rice J, Elliott T, Buchan S, Stevenson FK. DNA fusion vaccinedesigned to induce cytotoxic T cell responses against defined peptidemotifs: implications for cancer vaccines. J Immunol 2001; 167: 1558-65.
    • (2001) J Immunol , vol.167 , pp. 1558-1565
    • Rice, J.1    Elliott, T.2    Buchan, S.3    Stevenson, F.K.4
  • 6
    • 13044257108 scopus 로고    scopus 로고
    • High-efficiency gene transferinto skeletal muscle mediated by electric pulses
    • Mir LM, Bureau MF, Gehl J, et al. High-efficiency gene transferinto skeletal muscle mediated by electric pulses. Proc Natl Acad Sci USA 1999; 96(8): 4262-7.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.8 , pp. 4262-4267
    • Mir, L.M.1    Bureau, M.F.2    Gehl, J.3
  • 7
    • 33847273537 scopus 로고    scopus 로고
    • Electrotransfer as a non viral methodof gene delivery
    • Favard C, Dean DS, Rols MP. Electrotransfer as a non viral methodof gene delivery. Curr Gene Ther 2007; 7: 67-77.
    • (2007) Curr Gene Ther , vol.7 , pp. 67-77
    • Favard, C.1    Dean, D.S.2    Rols, M.P.3
  • 8
    • 57049129996 scopus 로고    scopus 로고
    • Efficiency of high-and lowvoltagepulse combinations for gene electrotransfer in muscle,liver, tumor, and skin
    • André FM, Gehl J, Sersa G, et al. Efficiency of high-and lowvoltagepulse combinations for gene electrotransfer in muscle,liver, tumor, and skin. Hum Gene Ther 2008; 19: 1261-71.
    • (2008) Hum Gene Ther , vol.19 , pp. 1261-1271
    • André, F.M.1    Gehl, J.2    Sersa, G.3
  • 9
    • 33846859783 scopus 로고    scopus 로고
    • Electric pulses applied prior to intramuscularDNA vaccination greatly improve the vaccine immunogenicity
    • Peng B, Zhao Y, Xu L, Xu Y. Electric pulses applied prior to intramuscularDNA vaccination greatly improve the vaccine immunogenicity. Vaccine 2007; 25: 2064-73.
    • (2007) Vaccine , vol.25 , pp. 2064-2073
    • Peng, B.1    Zhao, Y.2    Xu, L.3    Xu, Y.4
  • 10
    • 1842479734 scopus 로고    scopus 로고
    • In vivo electroporationimproves immune responses to DNA vaccination in sheep
    • Scheerlinck JP, Karlis J, Tjelle TE, et al. In vivo electroporationimproves immune responses to DNA vaccination in sheep. Vaccine 2004; 22: 1820-5.
    • (2004) Vaccine , vol.22 , pp. 1820-1825
    • Scheerlinck, J.P.1    Karlis, J.2    Tjelle, T.E.3
  • 11
    • 0037056017 scopus 로고    scopus 로고
    • Electroporationimproves the efficacy of DNA vaccines in large animals
    • Babiuk S, Baca-Estrada ME, Foldvari M, et al. Electroporationimproves the efficacy of DNA vaccines in large animals. Vaccine 2002; 20: 3399-408.
    • (2002) Vaccine , vol.20 , pp. 3399-3408
    • Babiuk, S.1    Baca-Estrada, M.E.2    Foldvari, M.3
  • 12
    • 0037056026 scopus 로고    scopus 로고
    • Improved cellular andhumoural immune responses against Mycobacterium tubercolosisantigens after intramuscular DNA immunisation combined withmuscle electroporation
    • Tollefsen S, Tjelle TE, Schneide J, et al. Improved cellular andhumoural immune responses against Mycobacterium tubercolosisantigens after intramuscular DNA immunisation combined withmuscle electroporation. Vaccine 2002; 20: 3370-3378.
    • (2002) Vaccine , vol.20 , pp. 3370-3378
    • Tollefsen, S.1    Tjelle, T.E.2    Schneide, J.3
  • 13
    • 0034283956 scopus 로고    scopus 로고
    • Distribution of DNA vaccinesdetermines their immunogenicity after intramuscular injectionin mice
    • Dupuis M, Denis-Mize K, Woo C, et al. Distribution of DNA vaccinesdetermines their immunogenicity after intramuscular injectionin mice. J Immunol 2000; 165: 2850-8.
    • (2000) J Immunol , vol.165 , pp. 2850-2858
    • Dupuis, M.1    Denis-Mize, K.2    Woo, C.3
  • 14
    • 18144446323 scopus 로고    scopus 로고
    • Increased DNA vaccinedelivery and immunogenicity by electroporation in vivo
    • Widera G, Austin M, Rabussay D, et al. Increased DNA vaccinedelivery and immunogenicity by electroporation in vivo. J Immunol 2000; 164: 4635-40.
    • (2000) J Immunol , vol.164 , pp. 4635-4640
    • Widera, G.1    Austin, M.2    Rabussay, D.3
  • 15
    • 56249136280 scopus 로고    scopus 로고
    • Electroporation ofskeletal muscle induces danger signal release and antigenpresentingcell recruitment independently of DNA vaccine administration
    • Chiarella P, Massi E, De Robertis M, et al. Electroporation ofskeletal muscle induces danger signal release and antigenpresentingcell recruitment independently of DNA vaccine administration. Expert Opin Biol Ther 2008; 8: 1645-57.
    • (2008) Expert Opin Biol Ther , vol.8 , pp. 1645-1657
    • Chiarella, P.1    Massi, E.2    De Robertis, M.3
  • 16
    • 0033766645 scopus 로고    scopus 로고
    • Control of viremia andprevention of clinical AIDS in rhesus monkeys by cytokineaugmentedDNA vaccination
    • Barouch DH, Santra S, Schmitz JE, et al. Control of viremia andprevention of clinical AIDS in rhesus monkeys by cytokineaugmentedDNA vaccination. Science 2000; 290: 486-92.
    • (2000) Science , vol.290 , pp. 486-492
    • Barouch, D.H.1    Santra, S.2    Schmitz, J.E.3
  • 17
    • 0041707861 scopus 로고    scopus 로고
    • Lasmid chemokinesand colony-stimulating factors enhance the immunogenicity ofDNA priming-viral vector boosting human immunodeficiency virustype 1 vaccines
    • Barouch DH, McKay PF, Sumida SM, et al. lasmid chemokinesand colony-stimulating factors enhance the immunogenicity ofDNA priming-viral vector boosting human immunodeficiency virustype 1 vaccines. J Virol 2003; 77: 8729-35.
    • (2003) J Virol , vol.77 , pp. 8729-8735
    • Barouch, D.H.1    McKay, P.F.2    Sumida, S.M.3
  • 21
    • 17644416719 scopus 로고    scopus 로고
    • Targeting the innate immuneresponse with improved vaccine adjuvants
    • Pashine A, Valiante NM, Ulmer JB. Targeting the innate immuneresponse with improved vaccine adjuvants. Nat Med 2005; 11:S63-S68.
    • (2005) Nat Med , vol.11
    • Pashine, A.1    Valiante, N.M.2    Ulmer, J.B.3
  • 22
    • 77958055212 scopus 로고    scopus 로고
    • 2008 Formulation for DNA delivery via electroporationin vivo From Electroporation protocols: Preclinical and clinicalgene medicine
    • Anwer K. 2008 Formulation for DNA delivery via electroporationin vivo From Electroporation protocols: preclinical and clinicalgene medicine. Meth Mol Biol 2005; 423: 77-89.
    • (2005) Meth Mol Biol , vol.423 , pp. 77-89
    • Anwer, K.1
  • 23
    • 0034893580 scopus 로고    scopus 로고
    • Optimisationof electrotransfer of plasmid into skeletal muscle by pretreatmentwith hyaluronidase-increased expression with reducedmuscle damage
    • McMahon JM, Signori E, Wells KE, Fazio VM, Wells DJ. Optimisationof electrotransfer of plasmid into skeletal muscle by pretreatmentwith hyaluronidase-increased expression with reducedmuscle damage. Gene Ther 2001; 8: 1264-70.
    • (2001) Gene Ther , vol.8 , pp. 1264-1270
    • McMahon, J.M.1    Signori, E.2    Wells, K.E.3    Fazio, V.M.4    Wells, D.J.5
  • 24
    • 0032926935 scopus 로고    scopus 로고
    • Electropermeabilization of skeletal muscle enhancesgene transfer in vivo
    • Mathiesen I. Electropermeabilization of skeletal muscle enhancesgene transfer in vivo. Gene Ther 1999; 6: 508-14.
    • (1999) Gene Ther , vol.6 , pp. 508-514
    • Mathiesen, I.1
  • 25
    • 44649113067 scopus 로고    scopus 로고
    • Application of electroporation gene therapy: Past, currentand future
    • Mir LM. Application of electroporation gene therapy: past, currentand future. Methods Mol Biol 2008; 423: 3-17.
    • (2008) Methods Mol Biol , vol.423 , pp. 3-17
    • Mir, L.M.1
  • 28
    • 36049015389 scopus 로고    scopus 로고
    • Electroporation-basedDNA immunisation:Translation to the clinic
    • Luxembourg A, Evams CF, Hannaman D. Electroporation-basedDNA immunisation:translation to the clinic. Exp Opin Biol Ther 2007; 7: 1647-64.
    • (2007) Exp Opin Biol Ther , vol.7 , pp. 1647-1664
    • Luxembourg, A.1    Evams, C.F.2    Hannaman, D.3
  • 29
    • 43249111930 scopus 로고    scopus 로고
    • DNA vaccines andtheir applications in veterinary practice: Current perspectives
    • Dhama K, Mahendran M, Gupta PK, Rai A. DNA vaccines andtheir applications in veterinary practice: current perspectives. Vet Res Commun 2008; 32: 341-56.
    • (2008) Vet Res Commun , vol.32 , pp. 341-356
    • Dhama, K.1    Mahendran, M.2    Gupta, P.K.3    Rai, A.4
  • 30
    • 0036150087 scopus 로고    scopus 로고
    • Electrochemotherapy of horses. Apreliminary clinical report
    • Rols MP, Tamzali Y, Teissie J. Electrochemotherapy of horses. Apreliminary clinical report. Bioelectrochemistry 2002; 55: 101-5.
    • (2002) Bioelectrochemistry , vol.55 , pp. 101-105
    • Rols, M.P.1    Tamzali, Y.2    Teissie, J.3
  • 31
    • 33847273537 scopus 로고    scopus 로고
    • Electrotransfer as non viral methodof gene delivery
    • Favard C, Dean DS, Rols MP. Electrotransfer as non viral methodof gene delivery. Curr Gene Ther 2007; 7: 67-77.
    • (2007) Curr Gene Ther , vol.7 , pp. 67-77
    • Favard, C.1    Dean, D.S.2    Rols, M.P.3
  • 32
    • 0347286952 scopus 로고    scopus 로고
    • Needle-free topicalelectroporation improves gene expression from plasmids administeredin porcine skin
    • Babiuk S, Baca-Estrada ME, Foldvari M, et al. Needle-free topicalelectroporation improves gene expression from plasmids administeredin porcine skin. Mol Ther 2003; 8: 992-8.
    • (2003) Mol Ther , vol.8 , pp. 992-998
    • Babiuk, S.1    Baca-Estrada, M.E.2    Foldvari, M.3
  • 34
    • 43949114521 scopus 로고    scopus 로고
    • Recruitment of antigen-presenting cells to the site of inoculation and augmentation ofhuman immunodeficiency virus type 1 DNA vaccine immunogenicityby in vivo electroporation
    • Liu J, Kjeken R, Mathiesen I, Barouch DH. Recruitment of antigen-presenting cells to the site of inoculation and augmentation ofhuman immunodeficiency virus type 1 DNA vaccine immunogenicityby in vivo electroporation. J Virol 2008; 82: 5643-9.
    • (2008) J Virol , vol.82 , pp. 5643-5649
    • Liu, J.1    Kjeken, R.2    Mathiesen, I.3    Barouch, D.H.4
  • 35
    • 34248382494 scopus 로고    scopus 로고
    • Effect of plasmid DNAvaccine design and in vivo electroporation on the resulting vaccinespecificimmune responses in rhesus macaques
    • Luckay A, Sidhu MK, Kjeken R, et al. Effect of plasmid DNAvaccine design and in vivo electroporation on the resulting vaccinespecificimmune responses in rhesus macaques. J Virol 2007; 81: 5257-69.
    • (2007) J Virol , vol.81 , pp. 5257-5269
    • Luckay, A.1    Sidhu, M.K.2    Kjeken, R.3
  • 38
    • 33750796905 scopus 로고    scopus 로고
    • Modulation of the immuneresponse induced by gene electrotransfer of a hepatitis C virusDNA vaccine in nonhuman primates
    • Capone S, Zampaglione I, Vitelli A, et al. Modulation of the immuneresponse induced by gene electrotransfer of a hepatitis C virusDNA vaccine in nonhuman primates. J Immunol 2006; 177: 7462-71.
    • (2006) J Immunol , vol.177 , pp. 7462-7471
    • Capone, S.1    Zampaglione, I.2    Vitelli, A.3
  • 39
    • 52649116635 scopus 로고    scopus 로고
    • Synergistic effect ofgene-electro transfer and adjuvant cytokines in increasing the potencyof hepatitis C virus genetic vaccination
    • Arcuri M, Cappelletti M, Zampaglione I, et al. Synergistic effect ofgene-electro transfer and adjuvant cytokines in increasing the potencyof hepatitis C virus genetic vaccination. J Gene Med 2008; 10: 1048-54.
    • (2008) J Gene Med , vol.10 , pp. 1048-1054
    • Arcuri, M.1    Cappelletti, M.2    Zampaglione, I.3
  • 40
    • 63949088560 scopus 로고    scopus 로고
    • Electroporationfor the delivery of DNA-based vaccines and immunotherapeutics:Current clinical development
    • Bodles-Brakhop AM, Heller R, Draghia-Akli, R. Electroporationfor the delivery of DNA-based vaccines and immunotherapeutics:current clinical development. Mol Ther 2009; 17: 585-92.
    • (2009) Mol Ther , vol.17 , pp. 585-592
    • Bodles-Brakhop, A.M.1    Heller, R.2    Draghia-Akli, R.3
  • 41
    • 23244456102 scopus 로고    scopus 로고
    • DNA vaccines: Progress andchallenges
    • Donnelly JJ, Wahren B, Liu MA. DNA vaccines: progress andchallenges. J Immunol 2005; 175: 633-9.
    • (2005) J Immunol , vol.175 , pp. 633-639
    • Donnelly, J.J.1    Wahren, B.2    Liu, M.A.3
  • 42
    • 38349056826 scopus 로고    scopus 로고
    • DNA immunization usingconstant-current electroporation affords long-term protection fromautochthonous mammary carcinomas in cancer-prone transgenicmice
    • Curcio C, Khan AS, Amici A, et al. DNA immunization usingconstant-current electroporation affords long-term protection fromautochthonous mammary carcinomas in cancer-prone transgenicmice. Cancer Gene Ther 2008; 15: 108-14.
    • (2008) Cancer Gene Ther , vol.15 , pp. 108-114
    • Curcio, C.1    Khan, A.S.2    Amici, A.3
  • 43
    • 4344672484 scopus 로고    scopus 로고
    • Phase I trial of DNAvaccination with a plasmid expressing prostate specific antigen inpatients with hormone-refractory prostate cancer
    • Pavlenko M, Roos AK, Lundqvist A, et al. Phase I trial of DNAvaccination with a plasmid expressing prostate specific antigen inpatients with hormone-refractory prostate cancer. Br J Cancer 2004; 91: 688-94.
    • (2004) Br J Cancer , vol.91 , pp. 688-694
    • Pavlenko, M.1    Roos, A.K.2    Lundqvist, A.3
  • 44
    • 21844444548 scopus 로고    scopus 로고
    • Immune monitoring in aphase 1 trial of a PSA DNA vaccine in patients with hormonerefractoryprostate cancer
    • Miller AM, Ozenci V, Kiessling R, Pisa P. Immune monitoring in aphase 1 trial of a PSA DNA vaccine in patients with hormonerefractoryprostate cancer. J Immunother 2005; 28: 389-95.
    • (2005) J Immunother , vol.28 , pp. 389-395
    • Miller, A.M.1    Ozenci, V.2    Kiessling, R.3    Pisa, P.4
  • 45
    • 44649084951 scopus 로고    scopus 로고
    • DNA vaccination for prostate cancer
    • Roos AK, King A, Pisa P. DNA vaccination for prostate cancer. Meth Mol Biol 2008; 423: 463-72.
    • (2008) Meth Mol Biol , vol.423 , pp. 463-472
    • Roos, A.K.1    King, A.2    Pisa, P.3
  • 46
    • 67349274372 scopus 로고    scopus 로고
    • Prostate stem cell antigen DNA vaccination breaks tolerance toself-antigen and inhibits prostate cancer growth
    • Ahmad S, Casey G, Sweeney P, Tangney M, O'Sullivan GC. Prostate stem cell antigen DNA vaccination breaks tolerance toself-antigen and inhibits prostate cancer growth. Mol Ther 2009; 17: 1101-08.
    • (2009) Mol Ther , vol.17 , pp. 1101-1108
    • Ahmad, S.1    Casey, G.2    Sweeney, P.3    Tangney, M.4    O'Sullivan, G.C.5
  • 48
    • 69749100779 scopus 로고    scopus 로고
    • + T cell responses and therapeuticantitumor effect by antigen engineering and electroporation
    • + T cell responses and therapeuticantitumor effect by antigen engineering and electroporation. Vaccine 2009; 27: 5906-12.
    • (2009) Vaccine , vol.27 , pp. 5906-5912
    • Seo, S.H.1    Jin, H.T.2    Park, S.H.3    Youn, J.I.4    Sung, Y.C.5
  • 49
    • 50849116106 scopus 로고    scopus 로고
    • Cellular immunity induced by anovel HPV18 DNA vaccine encoding an E6/E7 fusion consensusprotein in mice and rhesus macaques
    • Yan J, Harris K, Khan AS, et al. Cellular immunity induced by anovel HPV18 DNA vaccine encoding an E6/E7 fusion consensusprotein in mice and rhesus macaques. Vaccine 2008; 26: 5210-5.
    • (2008) Vaccine , vol.26 , pp. 5210-5215
    • Yan, J.1    Harris, K.2    Khan, A.S.3
  • 53
    • 44649110191 scopus 로고    scopus 로고
    • Delivery of DNA into skeletalmuscle in large animals
    • Brown PA, Khan AS, Draghia-Akli R. Delivery of DNA into skeletalmuscle in large animals. Meth Mol Biol 2008; 423: 215-24.
    • (2008) Meth Mol Biol , vol.423 , pp. 215-224
    • Brown, P.A.1    Khan, A.S.2    Draghia-Akli, R.3
  • 54
    • 63949083280 scopus 로고    scopus 로고
    • What is (still not) knownof the mechanism by which electroporation mediates gene transferand expression in cells and tissues
    • Escoffre JM, Portet T, Wasungu L, et al. What is (still not) knownof the mechanism by which electroporation mediates gene transferand expression in cells and tissues. Mol Biotechnol 2009; 41: 286-95.
    • (2009) Mol Biotechnol , vol.41 , pp. 286-295
    • Escoffre, J.M.1    Portet, T.2    Wasungu, L.3
  • 55
    • 75449087525 scopus 로고    scopus 로고
    • Electro-mediated genetransfer and expression are controlled by the life-time ofDNA/membrane complex formation
    • Faurie C, Rebersek M, Golzio M, et al. Electro-mediated genetransfer and expression are controlled by the life-time ofDNA/membrane complex formation. J Gene Med 2010; 12: 117-25.
    • (2010) J Gene Med , vol.12 , pp. 117-125
    • Faurie, C.1    Rebersek, M.2    Golzio, M.3
  • 56
    • 33747135384 scopus 로고    scopus 로고
    • DNA electroporation prime and proteinboost strategy enhances humoural immunity of tubercolosisDNA vaccine in mice and non-human primates
    • Li Z, Zhang H, Fan X, et al. DNA electroporation prime and proteinboost strategy enhances humoural immunity of tubercolosisDNA vaccine in mice and non-human primates. Vaccine 2006; 24: 4565-8.
    • (2006) Vaccine , vol.24 , pp. 4565-4568
    • Li, Z.1    Zhang, H.2    Fan, X.3
  • 57
    • 33646830656 scopus 로고    scopus 로고
    • Novel electroporationdevice for gene delivery in large animals and humans
    • Tjelle TE, Salte R, Mathiesen I, Kjeken RA. Novel electroporationdevice for gene delivery in large animals and humans. Vaccine 2006; 24: 4667-70.
    • (2006) Vaccine , vol.24 , pp. 4667-4670
    • Tjelle, T.E.1    Salte, R.2    Mathiesen, I.3    Kjeken, R.A.4
  • 58
    • 44649105094 scopus 로고    scopus 로고
    • Taking electroporation-based delivery of DNA vaccination intohumans: A generic clinical protocol Methods
    • Tjelle TE, Rabussay D, Ottensmeier C, Mathiesen I, Kjeken R. Taking electroporation-based delivery of DNA vaccination intohumans: a generic clinical protocol Methods. Mol Biol 2008; 423: 497-507.
    • (2008) Mol Biol , vol.423 , pp. 497-507
    • Tjelle, T.E.1    Rabussay, D.2    Ottensmeier, C.3    Mathiesen, I.4    Kjeken, R.5
  • 59
    • 33751051150 scopus 로고    scopus 로고
    • Standard operating procedures of theelectrochemotherapy: Instructions for the use of bleomycin or cysplatinadministered either systemically or locally and electric pulsesdelivered by the Cliniporator TM by means of invasive or noninvasiveelectrodes
    • Mir LM, Gehl J, Sensa G. Standard operating procedures of theelectrochemotherapy: instructions for the use of bleomycin or cysplatinadministered either systemically or locally and electric pulsesdelivered by the Cliniporator TM by means of invasive or noninvasiveelectrodes. Eur J Cancer 2006; 4(Suppl. 11): 14-25.
    • (2006) Eur J Cancer , vol.4 , Issue.SUPPL. 11 , pp. 14-25
    • Mir, L.M.1    Gehl, J.2    Sensa, G.3
  • 60
    • 4644371368 scopus 로고    scopus 로고
    • Gene therapy progress and prospects: Electroporationand other physical methods
    • Wells, DJ. Gene therapy progress and prospects: electroporationand other physical methods. Gene Ther 2004; 11: 1363-9.
    • (2004) Gene Ther , vol.11 , pp. 1363-1369
    • Wells, D.J.1
  • 61
    • 38549175830 scopus 로고    scopus 로고
    • DNA vaccines: Precisiontools for activating effective immunity against cancer
    • Rice J, Ottensmeier CH, Stevenson FK. DNA vaccines: precisiontools for activating effective immunity against cancer. Nat Rev Cancer 2008; 8: 108-20.
    • (2008) Nat Rev Cancer , vol.8 , pp. 108-120
    • Rice, J.1    Ottensmeier, C.H.2    Stevenson, F.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.