-
1
-
-
0032898667
-
Fatty acids, lipotoxicity and insulin secretion
-
DOI 10.1007/s001250051130
-
McGarry JD, Dobbins RL. Fatty acids, lipotoxicity and insulin secretion. Diabetologia 1999, 42: 128-38. (Pubitemid 29064233)
-
(1999)
Diabetologia
, vol.42
, Issue.2
, pp. 128-138
-
-
McGarry, J.D.1
Dobbins, R.L.2
-
2
-
-
0035130102
-
Diseases of liporegulation: New perspective on obesity and related disorders
-
DOI 10.1096/fj.00-0590
-
Unger RH, Orci L. Diseases of liporegulation: new perspective on obesity and related disorders. Faseb J 2001, 15: 312-21. (Pubitemid 32141423)
-
(2001)
FASEB Journal
, vol.15
, Issue.2
, pp. 312-321
-
-
Unger, R.H.1
Orci, L.2
-
3
-
-
0035125917
-
Lipotoxicity of beta-cells in obesity and in other causes of fatty acid spillover
-
Unger RH, Zhou YT. Lipotoxicity of beta-cells in obesity and in other causes of fatty acid spillover. Diabetes 2001, 50 (Suppl 1): S118-21. (Pubitemid 32148232)
-
(2001)
Diabetes
, vol.50
, Issue.SUPPL. 1
-
-
Unger, R.H.1
Zhou, Y.-T.2
-
4
-
-
8844255630
-
Free fatty acids in obesity and type 2 diabetes: Defining their role in the development of insulin resistance and beta-cell dysfunction
-
DOI 10.1046/j.1365-2362.32.s3.3.x
-
Boden G, Shulman GI. Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction. Eur J Clin Invest 2002, 32 (Suppl 3): 14-23. (Pubitemid 41704996)
-
(2002)
European Journal of Clinical Investigation
, vol.32
, Issue.SUPPL. 3
, pp. 14-23
-
-
Boden, G.1
Shulman, G.I.2
-
5
-
-
0028985060
-
Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids
-
Milbum JL, Hirose H, Lee YH, et al. Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids. J Biol Chem 1995, 270: 1295-9.
-
(1995)
J Biol Chem
, vol.270
, pp. 1295-1299
-
-
Milbum, J.L.1
Hirose, H.2
Lee, Y.H.3
-
6
-
-
0031683543
-
Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans
-
DOI 10.2337/diabetes.47.10.1613
-
Dobbins RL, Chester MW, Daniels MB, McGarry JD, Stein DT. Circulating fatty acids are essential for efficient glucose-stimulated insulin secretion after prolonged fasting in humans. Diabetes 1998, 47: 1613-8. (Pubitemid 28445350)
-
(1998)
Diabetes
, vol.47
, Issue.10
, pp. 1613-1618
-
-
Dobbins, R.L.1
Chester, M.W.2
Daniels, M.B.3
McGarry, J.D.4
Stein, D.T.5
-
7
-
-
0030821972
-
Improved sensitivity to insulin in obese subjects following weight loss is accompanied by reduced protein-tyrosine phosphatases in adipose tissue
-
DOI 10.1016/S0026-0495(97)90206-7
-
Ahmad F, Considine RV, Bauer TL, Ohannesian JP, Marco CC, Goldstein BJ. Improved sensitivity to insulin in obese subjects following weight loss is accompanied by reduced protein-tyrosine phosphatases in adipose tissue. Metabolism 1997, 46: 1140-5. (Pubitemid 27418501)
-
(1997)
Metabolism: Clinical and Experimental
, vol.46
, Issue.10
, pp. 1140-1145
-
-
Ahmad, F.1
Considine, R.V.2
Bauer, T.L.3
Ohannesian, J.P.4
Marco, C.C.5
Goldstein, B.J.6
-
8
-
-
0030840724
-
Alterations in skeletal muscle protein-tyrosine phosphatase activity and expression in insulin-resistant human obesity and diabetes
-
Ahmad F, Azevedo JL, Cortright R, Dohm GL, Goldstein BJ. Alterations in skeletal muscle protein-tyrosine phosphatase activity and expression in insulin-resistant human obesity and diabetes. J Clin Invest 1997, 100: 449-58. (Pubitemid 27349093)
-
(1997)
Journal of Clinical Investigation
, vol.100
, Issue.2
, pp. 449-458
-
-
Ahmad, F.1
Azevedo Jr., J.L.2
Cortright, R.3
Dohm, G.L.4
Goldstein, B.J.5
-
9
-
-
0038517834
-
Antisense protein tyrosine phosphatase 1B reverses activation of p38 mitogen-activated protein kinase in liver of ob/ob mice
-
DOI 10.1210/me.2002-0288
-
Gum RJ, Gaede LL, Heindel MA, et al. Antisense protein tyrosine phosphatase 1B reverses activation of p38 mitogen-activated protein kinase in liver of ob/ob mice. Mol Endocrinol 2003, 17: 1131-43. (Pubitemid 36683720)
-
(2003)
Molecular Endocrinology
, vol.17
, Issue.6
, pp. 1131-1143
-
-
Gum, R.J.1
Gaede, L.L.2
Heindel, M.A.3
Waring, J.F.4
Trevillyan, J.M.5
Zinker, B.A.6
Stark, M.E.7
Wilcox, D.8
Jirousek, M.R.9
Rondinone, C.M.10
Ulrich, R.G.11
-
10
-
-
7044260741
-
Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes
-
DOI 10.2337/diabetes.53.11.3007
-
Bento JL, Palmer ND, Mychaleckyj JC, et al. Association of protein tyrosine phosphatase 1B gene polymorphisms with type 2 diabetes. Diabetes 2004, 53: 3007-12. (Pubitemid 39425929)
-
(2004)
Diabetes
, vol.53
, Issue.11
, pp. 3007-3012
-
-
Bento, J.L.1
Palmer, N.D.2
Mychaleckyj, J.C.3
Lange, L.A.4
Langefeld, C.D.5
Rich, S.S.6
Freedman, B.I.7
Bowden, D.W.8
-
11
-
-
4143087179
-
Single nucleotide polymorphisms of protein tyrosine phosphatase 1B gene are associated with obesity in morbidly obese French subjects
-
Kipfer-Coudreau S, Eberlé D, Sahbatou M, et al. Single nucleotide polymorphisms of protein tyrosine phosphatase 1B gene are associated with obesity in morbidly obese French subjects. Diabetologia 2004, 47: 1278-84. (Pubitemid 39093324)
-
(2004)
Diabetologia
, vol.47
, Issue.7
, pp. 1278-1284
-
-
Kipfer-Coudreau, S.1
Eberle, D.2
Sahbatou, M.3
Bonhomme, A.4
Guy-Grand, B.5
Froguel, P.6
Galan, P.7
Basdevant, A.8
Clement, K.9
-
12
-
-
77957257786
-
Protein tyrosine phosphatase 1B gene polymorphisms and essential hypertension: A case-control study in Chinese population
-
Gu P, Jiang W, Du H, Shao J, Lu B, Wang J, Zou D. Protein tyrosine phosphatase 1B gene polymorphisms and essential hypertension: a case-control study in Chinese population. J Endocrinol Invest 2010, 33: 483-8.
-
(2010)
J Endocrinol Invest
, vol.33
, pp. 483-488
-
-
Gu, P.1
Jiang, W.2
Du, H.3
Shao, J.4
Lu, B.5
Wang, J.6
Zou, D.7
-
13
-
-
2642541849
-
Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action
-
DOI 10.1074/jbc.M310688200
-
Zabolotny JM, Haj FG, Kim YB, et al. Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action. J Biol Chem 2004, 279: 24844-51. (Pubitemid 38725352)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.23
, pp. 24844-24851
-
-
Zabolotny, J.M.1
Haj, F.G.2
Kim, Y.-B.3
Kim, H.-J.4
Shulman, G.I.5
Kim, J.K.6
Neel, B.G.7
Kahn, B.B.8
-
14
-
-
0035971065
-
Protein-tyrosine phosphatase-1B negatively regulates insulin signaling in I6 myocytes and Fao hepatoma cells
-
Egawa K, Maegawa H, Shimizu S, et al. Protein-tyrosine phosphatase-1B negatively regulates insulin signaling in I6 myocytes and Fao hepatoma cells. J Biol Chem 2001, 276: 10207-11.
-
(2001)
J Biol Chem
, vol.276
, pp. 10207-10211
-
-
Egawa, K.1
Maegawa, H.2
Shimizu, S.3
-
15
-
-
0033525870
-
Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1 B gene
-
Elchebly M, Payette P, Michaliszyn E, et al. Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1 B gene. Science 1999, 283: 1544-8.
-
(1999)
Science
, vol.283
, pp. 1544-1548
-
-
Elchebly, M.1
Payette, P.2
Michaliszyn, E.3
-
16
-
-
0033942614
-
Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice
-
DOI 10.1128/MCB.20.15.5479-5489.2000
-
Klaman LD, Boss O, Peroni OD, et al. Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice. Mol Cell Biol 2000, 20: 5479-89. (Pubitemid 30482885)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.15
, pp. 5479-5489
-
-
Klaman, L.D.1
Boss, O.2
Peroni, O.D.3
Kim, J.K.4
Martino, J.L.5
Zabolotny, J.M.6
Moghal, N.7
Lubkin, M.8
Kim, Y.-B.9
Sharpe, A.H.10
Stricker-Krongrad, A.11
Shulman, G.I.12
Neel, B.G.13
Kahn, B.B.14
-
17
-
-
0029088719
-
Glucose-induced insulin receptor tyrosine phosphorylation in insulin-secreting betacells
-
Rothenberg PL, Willison LD, Simon J, Wolf BA Glucose-induced insulin receptor tyrosine phosphorylation in insulin-secreting betacells. Diabetes 1995, 44: 802-9.
-
(1995)
Diabetes
, vol.44
, pp. 802-809
-
-
Rothenberg, P.L.1
Willison, L.D.2
Simon, J.3
Wolf, B.A.4
-
18
-
-
0029893530
-
Expression of insulin receptor mRNA and insulin receptor substrate 1 in pancreatic islet beta-cells
-
Harbeck MC, Louie DC, Howland J, Wolf BA, Rothenberg PL. Expression of insulin receptor mRNA and insulin receptor substrate 1 in pancreatic islet beta-cells. Diabetes 1996, 45: 711-7. (Pubitemid 26168581)
-
(1996)
Diabetes
, vol.45
, Issue.6
, pp. 711-717
-
-
Harbeck, M.C.1
Louie, D.C.2
Howland, J.3
Wolf, B.A.4
Rothenberg, P.L.5
-
19
-
-
0029955658
-
Wortmannin inhibits insulin secretion in pancreatic islets and beta-TC3 cells independent of its inhibition of phosphatidylinositol 3-kinase
-
Gao Z, Konrad RJ, Collins H, Matschinsky FM, Rothenberg PL, Wolf BA. Wortmannin inhibits insulin secretion in pancreatic islets and beta-TC3 cells independent of its inhibition of phosphatidylinositol 3-kinase. Diabetes 1996, 45: 854-62. (Pubitemid 26225498)
-
(1996)
Diabetes
, vol.45
, Issue.3 SUPPL.
, pp. 854-862
-
-
Gao, Z.-Y.1
Konrad, R.J.2
Collins, H.3
Matschinsky, F.M.4
Rothenberg, P.L.5
Wolf, B.A.6
-
20
-
-
0032061042
-
Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways
-
Leibiger IB, Leibiger B, Moede T, Berggren PO. Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways. Mol Cell 1998, 1: 933-8. (Pubitemid 128379078)
-
(1998)
Molecular Cell
, vol.1
, Issue.6
, pp. 933-938
-
-
Leibiger, I.B.1
Leibiger, B.2
Moede, T.3
Berggren, P.-O.4
-
21
-
-
0033581001
-
Insulin receptor substrate 1-induced inhibition of endoplasmic reticulum Ca2+ uptake in beta-cells. Autocrine regulation of intracellular ca2+ homeostasis and insulin secretion
-
Xu GG, Gao ZY, Borge PD Jr, Wolf BA. Insulin receptor substrate 1-induced inhibition of endoplasmic reticulum Ca2+ uptake in beta-cells. Autocrine regulation of intracellular ca2+ homeostasis and insulin secretion. J Biol Chem 1999, 274: 18067-74.
-
(1999)
J Biol Chem
, vol.274
, pp. 18067-18074
-
-
Xu, G.G.1
Gao, Z.Y.2
Borge Jr., P.D.3
Wolf, B.A.4
-
22
-
-
0033515429
-
Deconstructing type 2 diabetes
-
Taylor SI. Deconstructing type 2 diabetes. Cell 1999, 97: 9-12. (Pubitemid 29165884)
-
(1999)
Cell
, vol.97
, Issue.1
, pp. 9-12
-
-
Taylor, S.I.1
-
23
-
-
2942523253
-
Insulin secretory defects and impaired islet architecture in pancreatic beta-cell-specific STAT3 knockout mice
-
DOI 10.1016/j.bbrc.2004.05.095, PII S0006291X04010691
-
Gorogawa S, Fujitani Y, Kaneto H, et al. Insulin secretory defects and impaired islet architecture in pancreatic beta-cell specific STAT3 knockout mice. Biochem Biophys Res Commun 2004, 319: 1159-70. (Pubitemid 38759533)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.319
, Issue.4
, pp. 1159-1170
-
-
Gorogawa, S.-I.1
Fujitani, Y.2
Kaneto, H.3
Hazama, Y.4
Watada, H.5
Miyamoto, Y.6
Takeda, K.7
Akira, S.8
Magnuson, M.A.9
Yamasaki, Y.10
Kajimoto, Y.11
Hori, M.12
-
24
-
-
0028985060
-
Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids
-
Milburn JL Jr, Hirose H, Lee YH, et al. Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids. J Biol Chem 1995, 270: 1295-9.
-
(1995)
J Biol Chem
, vol.270
, pp. 1295-1299
-
-
Milburn Jr., J.L.1
Hirose, H.2
Lee, Y.H.3
-
25
-
-
0037733977
-
Antisense technologies: Improvement through novel chemical modifications
-
DOI 10.1046/j.1432-1033.2003.03555.x
-
Kurreck J. Antisense technologies. Improvement through novel chemical modifications. Eur J Biochem 2003, 270: 1628-44. (Pubitemid 36532522)
-
(2003)
European Journal of Biochemistry
, vol.270
, Issue.8
, pp. 1628-1644
-
-
Kurreck, J.1
-
26
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
DOI 10.1038/35078107
-
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001, 411: 494-8. (Pubitemid 32494397)
-
(2001)
Nature
, vol.411
, Issue.6836
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
27
-
-
0037134020
-
A system for stable expression of short interfering RNAs in mammalian cells
-
DOI 10.1126/science.1068999
-
Brummelkamp TR, Bernards R, Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 2002, 296: 550-3. (Pubitemid 34408678)
-
(2002)
Science
, vol.296
, Issue.5567
, pp. 550-553
-
-
Brummelkamp, T.R.1
Bernards, R.2
Agami, R.3
-
28
-
-
0030067124
-
A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm
-
Matschinsky FM. Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm. Diabetes 1996, 45: 223-41. (Pubitemid 26045806)
-
(1996)
Diabetes
, vol.45
, Issue.2
, pp. 223-241
-
-
Matschinsky, F.M.1
-
29
-
-
0025736821
-
Diabetic hyperglyeemia: Link to impaired glucose transport in pancreatic beta cells
-
Unger RH. Diabetic hyperglycemia: link to impaired glucose transport in pancreatic beta cells. Science 1991, 251: 1200-5. (Pubitemid 21926211)
-
(1991)
Science
, vol.251
, Issue.4998
, pp. 1200-1205
-
-
Unger, R.H.1
-
30
-
-
0030707689
-
Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2
-
DOI 10.1038/ng1197-327
-
Guillam MT, Hümmler E, Schaerer E, et al. Early diabetes and abnormal postnatal pancreatic islet development in mice lacking GLUT2. Nat Genet 1997, 17: 327-30. (Pubitemid 27475998)
-
(1997)
Nature Genetics
, vol.17
, Issue.3
, pp. 327-330
-
-
Guillam, M.-T.1
Hummler, E.2
Schaerer, E.3
Wu, J.-Y.4
Birnbaum, M.J.5
Beermann, F.6
Schmidt, A.7
Deriaz, N.8
Thorens, B.9
-
31
-
-
0031892853
-
Pancreatic beta-cell glucokinase: Closing the gap between theoretical concepts and experimental realities
-
DOI 10.2337/diabetes.47.3.307
-
Matschinsky FM, Glaser B, Magnuson MA. Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities. Diabetes 1998, 47: 307-15. (Pubitemid 28104189)
-
(1998)
Diabetes
, vol.47
, Issue.3
, pp. 307-315
-
-
Matschinsky, F.M.1
Glaser, B.2
Magnuson, M.A.3
-
32
-
-
0029417331
-
Pancreatic beta-cell-specific targeted disruption of glucokinase gene. Diabetes mellitus due to defective insulin secretion to glucose
-
Terauchi Y, Sakura H, Yasuda K, et al. Pancreatic beta-cell-specific targeted disruption of glucokinase gene. Diabetes mellitus due to defective insulin secretion to glucose. J Biol Chem 1995, 270: 30253-6.
-
(1995)
J Biol Chem
, vol.270
, pp. 30253-30256
-
-
Terauchi, Y.1
Sakura, H.2
Yasuda, K.3
|