PA from an H5N1 highly pathogenic avian influenza virus activates viral transcription and replication and induces apoptosis and interferon expression at an early stage of infection

Virology Journal

Volumn 9, Issue 1, 2012, Pages

  Wang, Qiang ^a   Zhang, Shijian ^a,b,c   Jiang, Hongbing ^a   Wang, Jinlan ^a   Weng, Leiyun ^a   Mao, Yingying ^a   Sekiguchi, Satoshi ^d   Yasui, Fumihiko ^d   Kohara, Michinori ^d   Buchy, Philippe ^e   Deubel, Vincent ^e   Xu, Ke ^a   Sun, Bing ^a   Toyoda, Tetsuya ^a,d,f  

^a INSTITUTE PASTEUR OF SHANGHAI   (China)

^b FUDAN UNIVERSITY   (China)

^c Roche R and D Center China Ltd   (China)

^d Tokyo Metropolitan Inst Technol   (Japan)

^e INSTITUT PASTEUR DU CAMBODGE   (Cambodia)

^f NAGOYA CITY UNIVERSITY   (Japan)

Author keywords

Apoptosis; Influenza virus; Interferon; PA; Replication; Transcription

Indexed keywords

BETA INTERFERON; CASPASE 3; CASPASE 8; CASPASE 9; INTERFERON; RNA DIRECTED DNA POLYMERASE; RNA POLYMERASE; PA PROTEIN, INFLUENZA VIRUSES; RNA DIRECTED RNA POLYMERASE; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE COURSE; EMBRYO; ENZYME ACTIVITY; FEMALE; FIBROBLAST; GENETIC TRANSFECTION; HISTOPATHOLOGY; IN VITRO STUDY; INFLUENZA A VIRUS (A CAMBODIA P0322095 2005(H1N1)); INFLUENZA A VIRUS (A PUERTO RICO 8 1934 (H1N1)); INFLUENZA A VIRUS (A WSN 1933 (H1N1)); INFLUENZA A VIRUS (H1N1); INFLUENZA A VIRUS (H5N1); LD50; LYMPHOCYTIC INFILTRATION; MDCK CELL LINE; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; REPLICON; T LYMPHOCYTE; TUNEL ASSAY; VERO CELL LINE; VIROGENESIS; VIRUS CELL INTERACTION; VIRUS REPLICATION; VIRUS STRAIN; VIRUS TRANSCRIPTION; VIRUS VIRULENCE; ANIMAL; BIOSYNTHESIS; CELL LINE; ENZYMOLOGY; GENETIC REASSORTMENT; GENETIC TRANSCRIPTION; HUMAN; IMMUNOLOGY; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H5N1; ORTHOMYXOVIRUS INFECTION; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; SURVIVAL; VIROLOGY; VIRUS LOAD;

ANIMALS; APOPTOSIS; CELL LINE; FEMALE; HUMANS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H5N1 SUBTYPE; INTERFERONS; MICE; MICE, INBRED BALB C; ORTHOMYXOVIRIDAE INFECTIONS; REASSORTANT VIRUSES; RNA REPLICASE; SURVIVAL ANALYSIS; TRANSCRIPTION, GENETIC; VIRAL LOAD; VIRAL PROTEINS; VIRUS REPLICATION;

EID: 84861928703     PISSN: None     EISSN: 1743422X     Source Type: Journal    
DOI: 10.1186/1743-422X-9-106     Document Type: Article

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