Genetic compatibility and virulence of reassortants derived from contemporary avian H5N1 and human H3N2 influenza A viruses

PLoS Pathogens

Volumn 4, Issue 5, 2008, Pages

  Chen, Li Mei ^a   Davis, C Todd ^a   Zhou, Hong ^a   Cox, Nancy J ^a   Donis, Ruben O ^a  

^a NATIONAL CENTER FOR IMMUNIZATION AND RESPIRATORY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA DIRECTED DNA POLYMERASE ALPHA; MEMBRANE PROTEIN;

ADAPTATION; ADOLESCENT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; ENZYME SUBUNIT; FEMALE; GENETIC COMPATIBILITY; GENETIC REASSORTMENT; HUMAN; HUMAN CELL; INFLUENZA VIRUS; INFLUENZA VIRUS A H3N2; INFLUENZA VIRUS A H5N1; MOLECULAR INTERACTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PANDEMIC; RISK ASSESSMENT; VIRUS GENOME; VIRUS REPLICATION; VIRUS VIRULENCE; ANIMAL; AVIAN INFLUENZA; BAGG ALBINO MOUSE; BIRD; DISEASE MODEL; GENETICS; HOST PATHOGEN INTERACTION; INFLUENZA; MOLECULAR GENETICS; PATHOGENICITY; PATHOPHYSIOLOGY; VIROLOGY; VIRULENCE; VIRUS GENE;

AVES; HUMAN INFLUENZA VIRUS; INFLUENZA A VIRUS; MAMMALIA; MUS; ORTHOMYXOVIRIDAE;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; BASE SEQUENCE; BIRDS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FEMALE; GENES, VIRAL; HOST-PATHOGEN INTERACTIONS; HUMANS; INFLUENZA A VIRUS, H3N2 SUBTYPE; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA IN BIRDS; INFLUENZA, HUMAN; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; REASSORTANT VIRUSES; VIRULENCE; VIRUS REPLICATION;

EID: 44949093451     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000072     Document Type: Article

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