Mutational and metal binding analysis of the endonuclease domain of the influenza virus polymerase PA subunit

Journal of Virology

Volumn 84, Issue 18, 2010, Pages 9096-9104

  Crépin, Thibaut ^a   Dias, Alexandre ^a   Palencia, Andrés ^a   Swale, Christopher ^a   Cusack, Stephen ^a   Ruigrok, Rob W H ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE; INFLUENZA VIRUS POLYMERASE; MAGNESIUM; MANGANESE; UNCLASSIFIED DRUG; VIRUS PROTEIN; DIVALENT CATION; MUTANT PROTEIN; PA PROTEIN, INFLUENZA VIRUSES; PROTEIN BINDING; RNA DIRECTED RNA POLYMERASE;

ARTICLE; BINDING AFFINITY; BINDING SITE; CALORIMETRY; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; INFLUENZA VIRUS; METAL BINDING; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; TRANSCRIPTION INITIATION; VIRUS MUTATION; WILD TYPE; CHEMICAL STRUCTURE; ENZYMOLOGY; GENETICS; KINETICS; METABOLISM; ORTHOMYXOVIRUS; POINT MUTATION; PROTEIN TERTIARY STRUCTURE;

CALORIMETRY; CATALYTIC DOMAIN; CATIONS, DIVALENT; ENDONUCLEASES; KINETICS; MAGNESIUM; MANGANESE; MODELS, MOLECULAR; MUTANT PROTEINS; ORTHOMYXOVIRIDAE; POINT MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RNA REPLICASE; VIRAL PROTEINS;

EID: 77956030336     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00995-10     Document Type: Article

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