메뉴 건너뛰기




Volumn 35, Issue 11, 2012, Pages 1725-1737

Metabotropic glutamate receptors (mGluR5) activate transient receptor potential canonical channels to improve the regularity of the respiratory rhythm generated by the pre-Bötzinger complex in mice

Author keywords

Breathing; Central pattern generator; Irregularity; Rhythm generation; Transient receptor potential

Indexed keywords

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; 2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 3,5 DIHYDROXYPHENYLGLYCINE; CALCIUM CHANNEL L TYPE; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR 5; TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL 3; TRANSIENT RECEPTOR POTENTIAL CHANNEL 7;

EID: 84861917831     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2012.08091.x     Document Type: Article
Times cited : (18)

References (76)
  • 1
    • 0030801095 scopus 로고    scopus 로고
    • Modulation of the spinal network for locomotion by substance P in the neonatal rat
    • Barthe, J.Y. & Clarac, F. (1997) Modulation of the spinal network for locomotion by substance P in the neonatal rat. Exp. Brain Res., 115, 485-492.
    • (1997) Exp. Brain Res. , vol.115 , pp. 485-492
    • Barthe, J.Y.1    Clarac, F.2
  • 2
    • 3142738725 scopus 로고    scopus 로고
    • Potassium model for slow (2-3Hz) in vivo neocortical paroxysmal oscillations
    • Bazhenov, M., Timofeev, I., Steriade, M. & Sejnowski, T.J. (2004) Potassium model for slow (2-3Hz) in vivo neocortical paroxysmal oscillations. J. Neurophysiol., 92, 1116-1132.
    • (2004) J. Neurophysiol. , vol.92 , pp. 1116-1132
    • Bazhenov, M.1    Timofeev, I.2    Steriade, M.3    Sejnowski, T.J.4
  • 3
    • 77950386337 scopus 로고    scopus 로고
    • Substance P modulation of TRPC3/7 channels improves respiratory rhythm regularity and ICAN-dependent pacemaker activity
    • Ben-Mabrouk, F. & Tryba, A.K. (2010) Substance P modulation of TRPC3/7 channels improves respiratory rhythm regularity and ICAN-dependent pacemaker activity. Eur. J. Neurosci., 31, 1219-1232.
    • (2010) Eur. J. Neurosci. , vol.31 , pp. 1219-1232
    • Ben-Mabrouk, F.1    Tryba, A.K.2
  • 4
    • 34548107308 scopus 로고    scopus 로고
    • TrpC3/C7 and Slo2.1 are molecular targets for metabotropic glutamate receptor signaling in rat striatal cholinergic interneurons
    • Berg, A.P., Sen, N. & Bayliss, D.A. (2007) TrpC3/C7 and Slo2.1 are molecular targets for metabotropic glutamate receptor signaling in rat striatal cholinergic interneurons. J. Neurosci., 27, 8845-8856.
    • (2007) J. Neurosci. , vol.27 , pp. 8845-8856
    • Berg, A.P.1    Sen, N.2    Bayliss, D.A.3
  • 5
    • 57449096751 scopus 로고    scopus 로고
    • Background sodium current underlying respiratory rhythm regularity
    • Chevalier, M., Ben Mabrouk, F. & Tryba, A.K. (2008) Background sodium current underlying respiratory rhythm regularity. Eur. J. Neurosci., 28, 2423-2433.
    • (2008) Eur. J. Neurosci. , vol.28 , pp. 2423-2433
    • Chevalier, M.1    Ben Mabrouk, F.2    Tryba, A.K.3
  • 7
    • 34547096726 scopus 로고    scopus 로고
    • Phosphatidylinositol 4,5-bisphosphate regulates inspiratory burst activity in the neonatal mouse pre-Botzinger complex
    • Crowder, E.A., Saha, M.S., Pace, R.W., Zhang, H., Prestwich, G.D. & Del Negro, C.A. (2007) Phosphatidylinositol 4, 5-bisphosphate regulates inspiratory burst activity in the neonatal mouse pre-Botzinger complex. J. Physiol., 582, 1047-1058.
    • (2007) J. Physiol. , vol.582 , pp. 1047-1058
    • Crowder, E.A.1    Saha, M.S.2    Pace, R.W.3    Zhang, H.4    Prestwich, G.D.5    Del Negro, C.A.6
  • 8
    • 42949169939 scopus 로고    scopus 로고
    • A 'group pacemaker' mechanism for respiratory rhythm generation
    • Del Negro, C.A. & Hayes, J.A. (2008) A 'group pacemaker' mechanism for respiratory rhythm generation. J. Physiol., 586, 2245-2246.
    • (2008) J. Physiol. , vol.586 , pp. 2245-2246
    • Del Negro, C.A.1    Hayes, J.A.2
  • 9
    • 0036848984 scopus 로고    scopus 로고
    • Persistent sodium current, membrane properties and bursting behavior of pre-botzinger complex inspiratory neurons in vitro
    • Del Negro, C.A., Koshiya, N., Butera, R.J.J. & Smith, J.C. (2002) Persistent sodium current, membrane properties and bursting behavior of pre-botzinger complex inspiratory neurons in vitro. J. Neurophysiol., 88, 224-250.
    • (2002) J. Neurophysiol. , vol.88 , pp. 224-250
    • Del Negro, C.A.1    Koshiya, N.2    Butera, R.J.J.3    Smith, J.C.4
  • 11
    • 78649481571 scopus 로고    scopus 로고
    • Synaptically activated burst-generating conductances may underlie a group-pacemaker mechanism for respiratory rhythm generation in mammals
    • Del Negro, C.A., Hayes, J.A., Pace, R.W., Brush, B.R., Teruyama, R. & Feldman, J.L. (2010) Synaptically activated burst-generating conductances may underlie a group-pacemaker mechanism for respiratory rhythm generation in mammals. Prog. Brain Res., 187, 111-136.
    • (2010) Prog. Brain Res. , vol.187 , pp. 111-136
    • Del Negro, C.A.1    Hayes, J.A.2    Pace, R.W.3    Brush, B.R.4    Teruyama, R.5    Feldman, J.L.6
  • 12
    • 70349328357 scopus 로고    scopus 로고
    • Group I mGluR activation enhances Ca(2+)-dependent nonselective cation currents and rhythmic bursting in main olfactory bulb external tufted cells
    • Dong, H.W., Hayar, A., Callaway, J., Yang, X.H., Nai, Q. & Ennis, M. (2009) Group I mGluR activation enhances Ca(2+)-dependent nonselective cation currents and rhythmic bursting in main olfactory bulb external tufted cells. J. Neurosci., 29, 11943-11953.
    • (2009) J. Neurosci. , vol.29 , pp. 11943-11953
    • Dong, H.W.1    Hayar, A.2    Callaway, J.3    Yang, X.H.4    Nai, Q.5    Ennis, M.6
  • 14
    • 0027436711 scopus 로고
    • Generation and transmission of respiratory oscillations in medullary slices: role of excitatory amino acids
    • Funk, G.D., Smith, J.C. & Feldman, J.L. (1993) Generation and transmission of respiratory oscillations in medullary slices: role of excitatory amino acids. J. Neurophysiol., 70, 1497-1515.
    • (1993) J. Neurophysiol. , vol.70 , pp. 1497-1515
    • Funk, G.D.1    Smith, J.C.2    Feldman, J.L.3
  • 15
    • 0030823387 scopus 로고    scopus 로고
    • Functional respiratory rhythm generating networks in neonatal mice lacking NMDAR1 gene
    • Funk, G.D., Johnson, S.M., Smith, J.C., Dong, X.W., Lai, J. & Feldman, J.L. (1997) Functional respiratory rhythm generating networks in neonatal mice lacking NMDAR1 gene. J. Neurophysiol., 78, 1414.
    • (1997) J. Neurophysiol. , vol.78 , pp. 1414
    • Funk, G.D.1    Johnson, S.M.2    Smith, J.C.3    Dong, X.W.4    Lai, J.5    Feldman, J.L.6
  • 16
    • 0034871003 scopus 로고    scopus 로고
    • Normal breathing requires preBotzinger complex neurokinin-1 receptor-expressing neurons
    • Gray, P.A., Janczewski, W.A., Mellen, N., McCrimmon, D.R. & Feldman, J.L. (2001) Normal breathing requires preBotzinger complex neurokinin-1 receptor-expressing neurons. Nat. Neurosci., 4, 927-930.
    • (2001) Nat. Neurosci. , vol.4 , pp. 927-930
    • Gray, P.A.1    Janczewski, W.A.2    Mellen, N.3    McCrimmon, D.R.4    Feldman, J.L.5
  • 17
    • 0025907057 scopus 로고
    • Role of excitatory amino acids in the generation and transmission of respiratory drive in neonatal rat
    • Greer, J.J., Smith, J.C. & Feldman, J.L. (1991) Role of excitatory amino acids in the generation and transmission of respiratory drive in neonatal rat. J. Physiol., 437, 727-749.
    • (1991) J. Physiol. , vol.437 , pp. 727-749
    • Greer, J.J.1    Smith, J.C.2    Feldman, J.L.3
  • 18
    • 33947189354 scopus 로고    scopus 로고
    • Biological pattern generation: the cellular and computational logic of networks in motion
    • Grillner, S. (2006) Biological pattern generation: the cellular and computational logic of networks in motion. Neuron, 52, 751-766.
    • (2006) Neuron , vol.52 , pp. 751-766
    • Grillner, S.1
  • 19
    • 0036583202 scopus 로고    scopus 로고
    • Neurokinin-1 receptor-expressing cells of the ventral respiratory group are functionally heterogeneous and predominantly glutamatergic
    • Guyenet, P.G., Sevigny, C.P., Weston, M.C. & Stornetta, R.L. (2002) Neurokinin-1 receptor-expressing cells of the ventral respiratory group are functionally heterogeneous and predominantly glutamatergic. J. Neurosci., 22, 3806.
    • (2002) J. Neurosci. , vol.22 , pp. 3806
    • Guyenet, P.G.1    Sevigny, C.P.2    Weston, M.C.3    Stornetta, R.L.4
  • 20
    • 0036901186 scopus 로고    scopus 로고
    • Voltage-sensitive ion channels in rhythmic motor systems
    • Harris-Warrick, R.M. (2002) Voltage-sensitive ion channels in rhythmic motor systems. Curr. Opin. Neurobiol., 12, 646-651.
    • (2002) Curr. Opin. Neurobiol. , vol.12 , pp. 646-651
    • Harris-Warrick, R.M.1
  • 21
    • 78649480325 scopus 로고    scopus 로고
    • General principles of rhythmogenesis in central pattern generator networks
    • Harris-Warrick, R.M. (2010) General principles of rhythmogenesis in central pattern generator networks. Prog. Brain Res., 187, 213-222.
    • (2010) Prog. Brain Res. , vol.187 , pp. 213-222
    • Harris-Warrick, R.M.1
  • 22
    • 0033601714 scopus 로고    scopus 로고
    • Heterogeneity of metabotropic glutamate receptors in autonomic cell groups of the medulla oblongata of the rat
    • Hay, M., McKenzie, H., Lindsley, K., Dietz, N., Bradley, S.R., Conn, P.J. & Hasser, E.M. (1999) Heterogeneity of metabotropic glutamate receptors in autonomic cell groups of the medulla oblongata of the rat. J. Comp. Neurol., 403, 486-501.
    • (1999) J. Comp. Neurol. , vol.403 , pp. 486-501
    • Hay, M.1    McKenzie, H.2    Lindsley, K.3    Dietz, N.4    Bradley, S.R.5    Conn, P.J.6    Hasser, E.M.7
  • 23
    • 0030886021 scopus 로고    scopus 로고
    • Effects of the neuroprotective agent riluzole on the high voltage-activated calcium channels of rat dorsal root ganglion neurons
    • Huang, C.-S., Song, J.-H., Nagata, K., Yeh, J.Z. & Narahashi, T. (1997) Effects of the neuroprotective agent riluzole on the high voltage-activated calcium channels of rat dorsal root ganglion neurons. J. Pharmacol. Exp. Ther., 282, 1280-1290.
    • (1997) J. Pharmacol. Exp. Ther. , vol.282 , pp. 1280-1290
    • Huang, C.-S.1    Song, J.-H.2    Nagata, K.3    Yeh, J.Z.4    Narahashi, T.5
  • 24
    • 42949122978 scopus 로고    scopus 로고
    • Distinct receptors underlie glutamatergic signalling in inspiratory rhythm-generating networks and motor output pathways in neonatal rat
    • Ireland, M.F., Lenal, F.C., Lorier, A.R., Loomes, D.E., Adachi, T., Alvares, T.S., Greer, J.J. & Funk, G.D. (2008) Distinct receptors underlie glutamatergic signalling in inspiratory rhythm-generating networks and motor output pathways in neonatal rat. J. Physiol., 586, 2357-2370.
    • (2008) J. Physiol. , vol.586 , pp. 2357-2370
    • Ireland, M.F.1    Lenal, F.C.2    Lorier, A.R.3    Loomes, D.E.4    Adachi, T.5    Alvares, T.S.6    Greer, J.J.7    Funk, G.D.8
  • 26
    • 0035065772 scopus 로고    scopus 로고
    • Isolation of the kernel for respiratory rhythm generation in a novel preparation: the pre-Botzinger complex 'island'
    • Johnson, S.M., Koshiya, N. & Smith, J.C. (2001) Isolation of the kernel for respiratory rhythm generation in a novel preparation: the pre-Botzinger complex 'island'. J. Neurophysiol., 85, 1772-1776.
    • (2001) J. Neurophysiol. , vol.85 , pp. 1772-1776
    • Johnson, S.M.1    Koshiya, N.2    Smith, J.C.3
  • 27
    • 34848880794 scopus 로고    scopus 로고
    • 2+ entry and TRPC expression; possible roles in cardiac pacemaker tissue
    • 2+ entry and TRPC expression; possible roles in cardiac pacemaker tissue. Heart Lung. Circ., 16, 349-355.
    • (2007) Heart Lung. Circ. , vol.16 , pp. 349-355
    • Ju, Y.-K.1    Allen, D.G.2
  • 28
    • 0036522972 scopus 로고    scopus 로고
    • Signaling mechanisms of metabotropic glutamate receptor 5 subtype and its endogenous role in a locomotor network
    • Kettunen, P., Krieger, P., Hess, D. & El Manira, A. (2002) Signaling mechanisms of metabotropic glutamate receptor 5 subtype and its endogenous role in a locomotor network. J. Neurosci., 22, 1868-1873.
    • (2002) J. Neurosci. , vol.22 , pp. 1868-1873
    • Kettunen, P.1    Krieger, P.2    Hess, D.3    El Manira, A.4
  • 29
    • 0142122313 scopus 로고    scopus 로고
    • mGluR1, but not mGluR5, mediates depolarization of spinal cord neurons by blocking a leak current
    • Kettunen, P., Hess, D. & Manira, A.E. (2003) mGluR1, but not mGluR5, mediates depolarization of spinal cord neurons by blocking a leak current. J. Neurophysiol., 90, 2341-2348.
    • (2003) J. Neurophysiol. , vol.90 , pp. 2341-2348
    • Kettunen, P.1    Hess, D.2    Manira, A.E.3
  • 30
    • 1242271194 scopus 로고    scopus 로고
    • Central pattern generators deciphered by molecular genetics
    • Kiehn, O. & Kullander, K. (2004) Central pattern generators deciphered by molecular genetics. Neuron, 41, 317-321.
    • (2004) Neuron , vol.41 , pp. 317-321
    • Kiehn, O.1    Kullander, K.2
  • 31
    • 33646695456 scopus 로고    scopus 로고
    • The relationship of TRP channels to the pacemaker activity of interstitial cells of Cajal in the gastrointestinal tract
    • Kim, B.J., So, I. & Kim, K.W. (2006) The relationship of TRP channels to the pacemaker activity of interstitial cells of Cajal in the gastrointestinal tract. J. Smooth Muscle Res., 42, 1-7.
    • (2006) J. Smooth Muscle Res. , vol.42 , pp. 1-7
    • Kim, B.J.1    So, I.2    Kim, K.W.3
  • 32
    • 0033595228 scopus 로고    scopus 로고
    • Neuronal pacemaker for breathing visualized in vitro
    • Koshiya, N. & Smith, J.C. (1999) Neuronal pacemaker for breathing visualized in vitro. Nature, 400, 360-363.
    • (1999) Nature , vol.400 , pp. 360-363
    • Koshiya, N.1    Smith, J.C.2
  • 33
    • 33646016327 scopus 로고    scopus 로고
    • Pattern-specific synaptic mechanisms in a multifunctional network. II. Intrinsic modulation by metabotropic glutamate receptors
    • Lieske, S.P. & Ramirez, J.-M. (2006) Pattern-specific synaptic mechanisms in a multifunctional network. II. Intrinsic modulation by metabotropic glutamate receptors. J. Neurophysiol., 95, 1334-1344.
    • (2006) J. Neurophysiol. , vol.95 , pp. 1334-1344
    • Lieske, S.P.1    Ramirez, J.-M.2
  • 34
    • 0035216305 scopus 로고    scopus 로고
    • Selective activation of group I metabotropic glutamate receptors upregulates preprodynorphin, substance P, and preproenkephalin mRNA expression in rat dorsal striatum
    • Mao, L. & Wang, J.Q. (2001) Selective activation of group I metabotropic glutamate receptors upregulates preprodynorphin, substance P, and preproenkephalin mRNA expression in rat dorsal striatum. Synapse, 39, 82-84.
    • (2001) Synapse , vol.39 , pp. 82-84
    • Mao, L.1    Wang, J.Q.2
  • 35
    • 46349088794 scopus 로고    scopus 로고
    • Unilateral ablation of Pre-Botzinger Complex disrupts breathing during sleep but not wakefulness
    • McKay, L.C. & Feldman, J.L. (2008) Unilateral ablation of Pre-Botzinger Complex disrupts breathing during sleep but not wakefulness. Am. J. Respir. Crit. Care Med., 178, 89-95.
    • (2008) Am. J. Respir. Crit. Care Med. , vol.178 , pp. 89-95
    • McKay, L.C.1    Feldman, J.L.2
  • 36
    • 27744538719 scopus 로고    scopus 로고
    • Sleep-disordered breathing after targeted ablation of preBotzinger complex neurons
    • McKay, L.C., Janczewski, W.A. & Feldman, J.L. (2005) Sleep-disordered breathing after targeted ablation of preBotzinger complex neurons. Nat. Neurosci., 8, 1142-1144.
    • (2005) Nat. Neurosci. , vol.8 , pp. 1142-1144
    • McKay, L.C.1    Janczewski, W.A.2    Feldman, J.L.3
  • 37
    • 42949154681 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors activate dendritic calcium waves and TRPM channels which drive rhythmic respiratory patterns in mice
    • Mironov, S.L. (2008) Metabotropic glutamate receptors activate dendritic calcium waves and TRPM channels which drive rhythmic respiratory patterns in mice. J. Physiol., 586, 2277-2291.
    • (2008) J. Physiol. , vol.586 , pp. 2277-2291
    • Mironov, S.L.1
  • 38
    • 0032191355 scopus 로고    scopus 로고
    • 2+ channels in inspiratory neurones of mice and their modulation by hypoxia
    • 2+ channels in inspiratory neurones of mice and their modulation by hypoxia. J. Physiol., 512, 75-87.
    • (1998) J. Physiol. , vol.512 , pp. 75-87
    • Mironov, S.L.1    Richter, D.W.2
  • 39
    • 0033961835 scopus 로고    scopus 로고
    • Intracellular signalling pathways modulate KATP channels in inspiratory brainstem neurones and their hypoxic activation: involvement of metabotropic receptors, G-proteins and cytoskeleton
    • Mironov, S.L. & Richter, D.W. (2000) Intracellular signalling pathways modulate KATP channels in inspiratory brainstem neurones and their hypoxic activation: involvement of metabotropic receptors, G-proteins and cytoskeleton. Brain Res., 853, 60-67.
    • (2000) Brain Res. , vol.853 , pp. 60-67
    • Mironov, S.L.1    Richter, D.W.2
  • 40
    • 79955968151 scopus 로고    scopus 로고
    • Calcium-activated non-selective cation currents are involved in generation of tonic and bursting activity in dopamine neurons of the substantia nigra pars compacta
    • Mrejeru, A., Wei, A. & Ramirez, J.M. (2011) Calcium-activated non-selective cation currents are involved in generation of tonic and bursting activity in dopamine neurons of the substantia nigra pars compacta. J. Physiol., 589, 2497-2514.
    • (2011) J. Physiol. , vol.589 , pp. 2497-2514
    • Mrejeru, A.1    Wei, A.2    Ramirez, J.M.3
  • 41
    • 0028817173 scopus 로고
    • Rat retrotrapezoid nucleus iono- and metabotropic glutamate receptors and the control of breathing
    • Nattie, E.E. & Li, A. (1995a) Rat retrotrapezoid nucleus iono- and metabotropic glutamate receptors and the control of breathing. J. Appl. Physiol., 78, 153-163.
    • (1995) J. Appl. Physiol. , vol.78 , pp. 153-163
    • Nattie, E.E.1    Li, A.2
  • 42
    • 0030039785 scopus 로고
    • Retrotrapezoid nucleus (RTN) metabotropic glutamate receptors and long-term stimulation of ventilatory output. RTN glutamate receptors and breathing
    • Nattie, E.E. & Li, A. (1995b) Retrotrapezoid nucleus (RTN) metabotropic glutamate receptors and long-term stimulation of ventilatory output. RTN glutamate receptors and breathing. Adv. Exp. Med. Biol., 393, 39-45.
    • (1995) Adv. Exp. Med. Biol. , vol.393 , pp. 39-45
    • Nattie, E.E.1    Li, A.2
  • 44
    • 57449115346 scopus 로고    scopus 로고
    • AMPA and metabotropic glutamate receptors cooperatively generate inspiratory-like depolarization in mouse respiratory neurons in vitro
    • Pace, R.W. & Del Negro, C.A. (2008) AMPA and metabotropic glutamate receptors cooperatively generate inspiratory-like depolarization in mouse respiratory neurons in vitro. Eur. J. Neurosci., 28, 2434-2442.
    • (2008) Eur. J. Neurosci. , vol.28 , pp. 2434-2442
    • Pace, R.W.1    Del Negro, C.A.2
  • 45
    • 34347267663 scopus 로고    scopus 로고
    • Inspiratory bursts in the pre-Botzinger complex depend on a calcium-activated non-specific cation current linked to glutamate receptors in neonatal mice
    • Pace, R.W., Mackay, D.D., Feldman, J.L. & Del Negro, C.A. (2007a) Inspiratory bursts in the pre-Botzinger complex depend on a calcium-activated non-specific cation current linked to glutamate receptors in neonatal mice. J. Physiol., 582, 113-125.
    • (2007) J. Physiol. , vol.582 , pp. 113-125
    • Pace, R.W.1    Mackay, D.D.2    Feldman, J.L.3    Del Negro, C.A.4
  • 46
    • 34147160256 scopus 로고    scopus 로고
    • Role of persistent sodium current in mouse preBotzinger Complex neurons and respiratory rhythm generation
    • Pace, R.W., Mackay, D.D., Feldman, J.L. & Del Negro, C.A. (2007b) Role of persistent sodium current in mouse preBotzinger Complex neurons and respiratory rhythm generation. J. Physiol., 580, 485-496.
    • (2007) J. Physiol. , vol.580 , pp. 485-496
    • Pace, R.W.1    Mackay, D.D.2    Feldman, J.L.3    Del Negro, C.A.4
  • 48
    • 17144410680 scopus 로고    scopus 로고
    • Serotonin refines the locomotor-related alternations in the in vitro neonatal rat spinal cord
    • Pearlstein, E., Ben Mabrouk, F., Pflieger, J. & Vinay, L. (2005) Serotonin refines the locomotor-related alternations in the in vitro neonatal rat spinal cord. Eur. J. Neurosci., 21, 1338-1346.
    • (2005) Eur. J. Neurosci. , vol.21 , pp. 1338-1346
    • Pearlstein, E.1    Ben Mabrouk, F.2    Pflieger, J.3    Vinay, L.4
  • 49
    • 33947130916 scopus 로고    scopus 로고
    • Effects of riluzole and flufenamic acid on eupnea and gasping of neonatal mice in vivo
    • Peña, F. & Aguileta, M.-A. (2007) Effects of riluzole and flufenamic acid on eupnea and gasping of neonatal mice in vivo. Neurosci. Lett., 415, 288-293.
    • (2007) Neurosci. Lett. , vol.415 , pp. 288-293
    • Peña, F.1    Aguileta, M.-A.2
  • 50
    • 0034669136 scopus 로고    scopus 로고
    • Seizures and neurodegeneration induced by 4-aminopyridine in rat hippocampus in vivo: role of glutamate- and GABA-mediated neurotransmission and of ion channels
    • Peña, F. & Tapia, R. (2000) Seizures and neurodegeneration induced by 4-aminopyridine in rat hippocampus in vivo: role of glutamate- and GABA-mediated neurotransmission and of ion channels. Neuroscience, 101, 547-561.
    • (2000) Neuroscience , vol.101 , pp. 547-561
    • Peña, F.1    Tapia, R.2
  • 51
    • 3242664430 scopus 로고    scopus 로고
    • Differential contribution of pacemaker properties to the generation of respiratory rhythms during normoxia and hypoxia
    • Pena, F., Parkis, M.A., Tryba, A.K. & Ramirez, J.-M. (2004) Differential contribution of pacemaker properties to the generation of respiratory rhythms during normoxia and hypoxia. Neuron, 43, 105-117.
    • (2004) Neuron , vol.43 , pp. 105-117
    • Pena, F.1    Parkis, M.A.2    Tryba, A.K.3    Ramirez, J.-M.4
  • 52
    • 0032521102 scopus 로고    scopus 로고
    • Selective lesioning of the cat pre-Botzinger Complex in vivo eliminates breathing but not gasping
    • Ramirez, J.M., Schwarzacher, S.W., Pierrefiche, O., Olivera, B.M. & Richter, D.W. (1998) Selective lesioning of the cat pre-Botzinger Complex in vivo eliminates breathing but not gasping. J. Physiol., 507, 895.
    • (1998) J. Physiol. , vol.507 , pp. 895
    • Ramirez, J.M.1    Schwarzacher, S.W.2    Pierrefiche, O.3    Olivera, B.M.4    Richter, D.W.5
  • 53
    • 9644294519 scopus 로고    scopus 로고
    • Pacemaker neurons and neuronal networks: an integrative view
    • Ramirez, J.M., Tryba, A.K. & Pena, F. (2004) Pacemaker neurons and neuronal networks: an integrative view. Curr. Opin. Neurobiol., 14, 665-674.
    • (2004) Curr. Opin. Neurobiol. , vol.14 , pp. 665-674
    • Ramirez, J.M.1    Tryba, A.K.2    Pena, F.3
  • 54
    • 0031596646 scopus 로고    scopus 로고
    • Pre-Botzinger Complex and pacemaker neurons: hypothesized site and kernel for respiratory rhythm generation
    • Rekling, J.C. & Feldman, J.L. (1998) Pre-Botzinger Complex and pacemaker neurons: hypothesized site and kernel for respiratory rhythm generation. Annu. Rev. Physiol., 60, 385.
    • (1998) Annu. Rev. Physiol. , vol.60 , pp. 385
    • Rekling, J.C.1    Feldman, J.L.2
  • 55
    • 45649084348 scopus 로고    scopus 로고
    • Effects of subtype-selective group I mGluR antagonists on synchronous activity induced by 4-aminopyridine/CGP 55845 in adult guinea pig hippocampal slices
    • Salah, A. & Perkins, K.L. (2008) Effects of subtype-selective group I mGluR antagonists on synchronous activity induced by 4-aminopyridine/CGP 55845 in adult guinea pig hippocampal slices. Neuropharmacology, 55, 47-54.
    • (2008) Neuropharmacology , vol.55 , pp. 47-54
    • Salah, A.1    Perkins, K.L.2
  • 56
    • 4544245502 scopus 로고    scopus 로고
    • Activation of group I metabotropic glutamate receptors enhances efficacy of glutamatergic inputs to neonatal rat hypoglossal motoneurons in vitro
    • Sharifullina, E., Ostroumov, K. & Nistri, A. (2004) Activation of group I metabotropic glutamate receptors enhances efficacy of glutamatergic inputs to neonatal rat hypoglossal motoneurons in vitro. Eur. J. Neurosci., 20, 1245-1254.
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 1245-1254
    • Sharifullina, E.1    Ostroumov, K.2    Nistri, A.3
  • 57
    • 14844283153 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor activity induces a novel oscillatory pattern in neonatal rat hypoglossal motoneurones
    • Sharifullina, E., Ostroumov, K. & Nistri, A. (2005) Metabotropic glutamate receptor activity induces a novel oscillatory pattern in neonatal rat hypoglossal motoneurones. J. Physiol., 563, 139-159.
    • (2005) J. Physiol. , vol.563 , pp. 139-159
    • Sharifullina, E.1    Ostroumov, K.2    Nistri, A.3
  • 58
    • 0031036733 scopus 로고    scopus 로고
    • Effects of riluzole on rat cortical neurones: an in vitro electrophysiological study
    • Siniscalchi, A., Bonci, A., Mercuri, N.B. & Bernardi, G. (1997) Effects of riluzole on rat cortical neurones: an in vitro electrophysiological study. Br. J. Pharmacol., 120, 225-230.
    • (1997) Br. J. Pharmacol. , vol.120 , pp. 225-230
    • Siniscalchi, A.1    Bonci, A.2    Mercuri, N.B.3    Bernardi, G.4
  • 59
    • 0026360052 scopus 로고
    • Pre-Botzinger Complex: a brainstem region that may generate respiratory rhythm in mammals
    • Smith, J.C., Ellenberger, H.H., Ballanyi, K., Richter, D.W. & Feldman, J.L. (1991) Pre-Botzinger Complex: a brainstem region that may generate respiratory rhythm in mammals. Science, 254, 726.
    • (1991) Science , vol.254 , pp. 726
    • Smith, J.C.1    Ellenberger, H.H.2    Ballanyi, K.3    Richter, D.W.4    Feldman, J.L.5
  • 60
    • 0031239776 scopus 로고    scopus 로고
    • Differential inhibition by riluzole, lamotrigine, and phenytoin of sodium and calcium currents in cortical neurons: implications for neuroprotective strategies
    • Stefani, A., Spadoni, F. & Bernardi, G. (1997) Differential inhibition by riluzole, lamotrigine, and phenytoin of sodium and calcium currents in cortical neurons: implications for neuroprotective strategies. Exp. Neurol., 147, 115-122.
    • (1997) Exp. Neurol. , vol.147 , pp. 115-122
    • Stefani, A.1    Spadoni, F.2    Bernardi, G.3
  • 61
    • 12344306177 scopus 로고    scopus 로고
    • Maintenance of eupnea and gasping following alterations in potassium ion concentration of perfusates of in situ rat preparation
    • St.-John, W.M., Rudkin, A.H., Harris, M.R., Leiter, J.C. & Paton, J.F.R. (2005) Maintenance of eupnea and gasping following alterations in potassium ion concentration of perfusates of in situ rat preparation. J. Neurosci. Methods, 142, 125-129.
    • (2005) J. Neurosci. Methods , vol.142 , pp. 125-129
    • St John, W.M.1    Rudkin, A.H.2    Harris, M.R.3    Leiter, J.C.4    Paton, J.F.R.5
  • 62
    • 42649112394 scopus 로고    scopus 로고
    • Silencing preBotzinger complex somatostatin-expressing neurons induces persistent apnea in awake rat
    • Tan, W., Janczewski, W.A., Yang, P., Shao, X.M., Callaway, E.M. & Feldman, J.L. (2008) Silencing preBotzinger complex somatostatin-expressing neurons induces persistent apnea in awake rat. Nat. Neurosci., 11, 538-540.
    • (2008) Nat. Neurosci. , vol.11 , pp. 538-540
    • Tan, W.1    Janczewski, W.A.2    Yang, P.3    Shao, X.M.4    Callaway, E.M.5    Feldman, J.L.6
  • 63
    • 0036318234 scopus 로고    scopus 로고
    • Long-term deprivation of Substance P in PPT-A mutant mice alters the anoxic response of the isolated respiratory network
    • Telgkamp, P., Cao, Y.Q., Basbaum, A.I. & Ramirez, J.-M. (2002) Long-term deprivation of Substance P in PPT-A mutant mice alters the anoxic response of the isolated respiratory network. J. Neurophysiol., 88, 206-213.
    • (2002) J. Neurophysiol. , vol.88 , pp. 206-213
    • Telgkamp, P.1    Cao, Y.Q.2    Basbaum, A.I.3    Ramirez, J.-M.4
  • 64
    • 0034946418 scopus 로고    scopus 로고
    • Identification of two types of inspiratory pacemaker neurons in the isolated respiratory neural network of mice
    • Thoby-Brisson, M. & Ramirez, J.-M. (2001) Identification of two types of inspiratory pacemaker neurons in the isolated respiratory neural network of mice. J. Neurophysiol., 86, 104-112.
    • (2001) J. Neurophysiol. , vol.86 , pp. 104-112
    • Thoby-Brisson, M.1    Ramirez, J.-M.2
  • 65
    • 0038617805 scopus 로고    scopus 로고
    • Response of the respiratory network of mice to hyperthermia
    • Tryba, A.K. & Ramirez, J.M. (2003) Response of the respiratory network of mice to hyperthermia. J. Neurophysiol., 89, 2975-2983.
    • (2003) J. Neurophysiol. , vol.89 , pp. 2975-2983
    • Tryba, A.K.1    Ramirez, J.M.2
  • 66
    • 14844321324 scopus 로고    scopus 로고
    • Hyperthermia modulates respiratory pacemaker bursting properties
    • Tryba, A.K. & Ramirez, J.-M. (2004) Hyperthermia modulates respiratory pacemaker bursting properties. J. Neurophysiol., 92, 2844-2852.
    • (2004) J. Neurophysiol. , vol.92 , pp. 2844-2852
    • Tryba, A.K.1    Ramirez, J.-M.2
  • 67
    • 0038333633 scopus 로고    scopus 로고
    • Stabilization of bursting in respiratory pacemaker neurons
    • Tryba, A.K., Pena, F. & Ramirez, J.-M. (2003) Stabilization of bursting in respiratory pacemaker neurons. J. Neurosci., 23, 3538-3546.
    • (2003) J. Neurosci. , vol.23 , pp. 3538-3546
    • Tryba, A.K.1    Pena, F.2    Ramirez, J.-M.3
  • 68
    • 33644820352 scopus 로고    scopus 로고
    • Gasping activity in vitro: a rhythm dependent on 5-HT2A receptors
    • Tryba, A.K., Pena, F. & Ramirez, J.-M. (2006) Gasping activity in vitro: a rhythm dependent on 5-HT2A receptors. J. Neurosci., 26, 2623-2634.
    • (2006) J. Neurosci. , vol.26 , pp. 2623-2634
    • Tryba, A.K.1    Pena, F.2    Ramirez, J.-M.3
  • 69
    • 47549104755 scopus 로고    scopus 로고
    • Differential modulation of neural network and pacemaker activity underlying eupnea and sigh-breathing activities
    • Tryba, A.K., Pena, F., Lieske, S.P., Viemari, J.-C., Thoby-Brisson, M. & Ramirez, J.-M. (2008) Differential modulation of neural network and pacemaker activity underlying eupnea and sigh-breathing activities. J. Neurophysiol., 99, 2114-2125.
    • (2008) J. Neurophysiol. , vol.99 , pp. 2114-2125
    • Tryba, A.K.1    Pena, F.2    Lieske, S.P.3    Viemari, J.-C.4    Thoby-Brisson, M.5    Ramirez, J.-M.6
  • 71
    • 0033787252 scopus 로고    scopus 로고
    • Riluzole inhibits the persistent sodium current in mammalian CNS neurons
    • Urbani, A. & Belluzzi, O. (2000) Riluzole inhibits the persistent sodium current in mammalian CNS neurons. Eur. J. Neurosci., 12, 3567-3574.
    • (2000) Eur. J. Neurosci. , vol.12 , pp. 3567-3574
    • Urbani, A.1    Belluzzi, O.2
  • 73
    • 80955178813 scopus 로고    scopus 로고
    • Activation of alpha-2 noradrenergic receptors is critical for the generation of fictive eupnea and fictive gasping inspiratory activities in mammals in vitro
    • Viemari, J.-C., Garcia, A.J. III, Doi, A. & Ramirez, J.-M. (2011) Activation of alpha-2 noradrenergic receptors is critical for the generation of fictive eupnea and fictive gasping inspiratory activities in mammals in vitro. Eur. J. Neurosci., 33, 2228-2237.
    • (2011) Eur. J. Neurosci. , vol.33 , pp. 2228-2237
    • Viemari, J.-C.1    Garcia III, A.J.2    Doi, A.3    Ramirez, J.-M.4
  • 75
    • 34247507769 scopus 로고    scopus 로고
    • Persistent sodium currents participate in fictive locomotion generation in neonatal mouse spinal cord
    • Zhong, G., Masino, M.A. & Harris-Warrick, R.M. (2007) Persistent sodium currents participate in fictive locomotion generation in neonatal mouse spinal cord. J. Neurosci., 27, 4507-4518.
    • (2007) J. Neurosci. , vol.27 , pp. 4507-4518
    • Zhong, G.1    Masino, M.A.2    Harris-Warrick, R.M.3
  • 76
    • 0031901783 scopus 로고    scopus 로고
    • Riluzole interacts with voltage-activated sodium and potassium currents in cultured rat cortical neurons
    • Zona, C., Siniscalchi, A., Mercuri, N.B. & Bernardi, G. (1998) Riluzole interacts with voltage-activated sodium and potassium currents in cultured rat cortical neurons. Neuroscience, 85, 931-938.
    • (1998) Neuroscience , vol.85 , pp. 931-938
    • Zona, C.1    Siniscalchi, A.2    Mercuri, N.B.3    Bernardi, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.