Functional respiratory rhythm generating networks in neonatal mice lacking NMDAR1 gene

Journal of Neurophysiology

Volumn 78, Issue 3, 1997, Pages 1414-1420

  Funk, G D ^a,c   Johnson, S M ^a,d   Smith, J C ^a,e   Dong, X W ^a   Lai, J ^a   Feldman, J L ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

^d UNIVERSITY OF WISCONSIN MADISON   (United States)

^e NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BREATHING MECHANICS; BREATHING PATTERN; MOUSE; NERVE CELL NETWORK; NEWBORN; NONHUMAN; PRIORITY JOURNAL; SLOW INWARD CURRENT; SPINAL CORD MOTONEURON; SYNAPTIC TRANSMISSION;

EID: 0030823387     PISSN: 00223077     EISSN: None     Source Type: Journal    
DOI: 10.1152/jn.1997.78.3.1414     Document Type: Article

References (48)

1. BEAR, M. F., KLEINSCHMIDT, A., Gu, Q., AND SINGER, W. Disruption of experience-dependent synaptic modification in striate cortex by infusion of an NMDA receptor antagonist. J. Neurosci. 10: 909-925, 1990.
2. BERGER, A. J. Recent advances in respiratory neurobiology using in vitro methods. Am. J. Physiol. 259 (Lung Cell. Mol Physiol. 2): L24-L29, 1990.
3. BLANTON, M. G., LOTURCO, J. J., AND KRIEGSTEIN, A. J. Whole-cell recordings from neurons in slices of reptilian and mammalian cerebral cortex. J. Neurosci. Methods 30: 203-210, 1989.
4. CLINE, H. T., DEBSKI, E., AND CONSTANTINE-PATON, M. NMDA receptor antagonist desegregates eye-specific stripes. Proc. Natl. Acad. Sci. USA 84: 4342-4345, 1987.
5. CONNELLY, C. A., OTTO-SMITH, M. R., AND FELDMAN, J. L. Blockade of NMDA receptor-channels by MK-801 alters breathing in rats. Brain Res. 596: 99-110, 1992.
6. CONQUET, F., BASHIR, Z. I., DAVIES, C. H., DANIEL, H., FERRAGUTI, F., BORDI, F., FRANZ-BACON, K., REGGIANI, A., MATARESE, V., CONDE, F., AND COLLINGRIDGE, G. L. Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1. Nature 372: 237-243, 1994.
7. DUFFIN, J., EZURE, K., AND LIPSKI, J. Breathing rhythm generation: focus on the rostral ventrolateral medulla. NIPS 10: 133-140, 1995.
8. FELDMAN, J. L. AND GAUTIER, H. Interaction of pulmonary afferents and pneumotaxic center in the control of respiratory pattern in cats. J. Neurophysiol. 39: 31-44, 1976.
9. FELDMAN, J. L., WINDHORST, U., ANDERS, K., AND RICHTER, D. W. Synaptic interactions between medullary respiratory neurones during apneusis induced by NMDA-receptor blockade in cat. J. Physiol. (Lond.) 450: 303-323, 1992.
10. FELDMAN, J. L., LI, Y., FUNK, G. D., SMITH, J. C., DONG, X.-W., JOHNSON, S. M., LAI, J., Hsu, S., AND TONEGAWA, S. Neonatal mice lacking functional NMDA receptors generate respiratory oscillations in vivo and in vitro. Soc. Neurosci. Abstr. 19: 925, 1993.
11. FELDMAN, J. L. AND SMITH, J. C. Neural control of respiratory pattern in mammals: an overview. In: Lung Biology in Health and Disease: Regulation of Breathing, edited by J. A. Dempsey and A. I. Pack. New York: Marcel Dekker, 1994, vol. 79, p. 36-69.
12. FIELDS, R. D., Yu, C., AND NELSON, P. G. Calcium, network activity and the role of NMDA channels in synaptic plasticity in vitro. J. Neurosci. 11: 134-146, 1991.
13. FORREST, D., YUZAKI, M., SOARES, H. D., NG, L., LUK, D. C., SHENG, M., STEWART, C. L., MORGAN, J. I., CONNOR, J. A., AND CURRAN, T. Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death. Neuron 13: 325-338, 1994.
14. FOUTZ, A. S., CHAMPAGNAT, J., AND DENAVIT-SAUBIE, M. N-methyl-D-aspartate (NMDA) receptors control respiratory off-switch in cat. Neurosci. Lett. 87: 221-226, 1988.
15. FOUTZ, A. S., CHAMPAGNAT, J., AND DENAVIT-SAUBIE, M. Involvement of N-methyl-D-aspartate (NMDA) receptors in respiratory rhythmogenesis. Brain Res. 500: 199-208, 1989.
16. FUNK, G. D. AND FELDMAN, J. L. Generation of respiratory rhythm and pattern in mammals: insights from developmental studies. Curr. Opin. Neurobiol 5: 778-785, 1995.
17. FUNK, G. D., SMITH, J. C., AND FELDMAN, J. L. Generation and transmission of respiratory oscillations in medullary slices: role of excitatory amino acids. J. Neurophysiol. 70: 1497-1515, 1993.
18. FUNK, G. D., SMITH, J. C., AND FELDMAN, J. L. Development of thyrotropin-releasing hormone and norepinephrine potentiation of inspiratory-related hypoglossal motoneuron discharge in neonatal and juvenile mice in vitro. J. Neurophysiol. 72: 2538-2541, 1994.
19. GREER, J. J., SMITH, J. C., AND FELDMAN, J. L. Role of excitatory amino acids in the generation and transmission of respiratory drive in neonatal rat. J. Physiol. (Lond.) 437: 727-749, 1991.
20. HADDAD, G. G., DONNELLY, D. F., AND BAZZY-ASAAD, D. Developmental control of respiration: neurobiological basis. In: Lung Biology in Health and Disease: Regulation of Breathing, edited by J. A. Dempsey and A. I. Pack. New York: Marcel Dekker, 1994, vol. 79, p. 743-796.
21. HAHM, J.-O., LANGDON, R. B., AND SUR, M. Disruption of retinogeniculate afferent segregation by antagonists to NMDA receptors. Nature 351: 568-570, 1991.
22. JANSEN, A. AND CHERNICK, V. Fetal breathing and development of control of breathing. J. Appl. Physiol. 70: 1431-1446, 1991.
23. KALB, R. G. AND HOCKFIELD, S. Molecular evidence for early-activity dependent development of hamster motoneurons. J. Neurosci. 8: 2350-2360, 1988.
24. KALB, R. G. AND HOCKFIELD, S. Induction of a neuronal proteoglycan by the NMDA receptor in the developing spinal cord. Science 250: 294-296, 1990.
25. KALB, R. G. AND HOCKFIELD, S. Activity-dependent development of spinal cord motoneurons. Brain Res. Rev. 17: 283-289, 1992.
26. KLEINSCHMIDT, A., BEAR, M. F., AND SINGER, W. Blockade of NMDA receptors disrupts experience-dependent plasticity of kitten striate cortex. Science 238: 355-358, 1987.
27. KUTSUWADA, T., SAKIMURA, K., MANABE, T., TAKAYAMA, C., KATAKURA, N., KUSHIYA, E., NATSUME, R., WATANABE, M., INOUE, Y., YAGI, T., ALZAWA, S., ARAKAWA, M., TAKAHASHI, T., NAKAMURA, Y., MORI, H., AND MISHINA, M. Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor 2 subunit mutant mice. Neuron 16: 333-344, 1996.
28. LI, Y., ERZURUMLU, R. S., CHEN, C., JHAVERI, S., AND TONEGAWA, S. Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice. Cell 76: 427-437, 1994.
29. LIU, G., FELDMAN, J. L., AND SMITH J. C. Excitatory amino acid-mediated transmission of inspiratory drive to phrenic motoneurons. J. Neurophysiol. 64: 423-436, 1990.
30. MCCRIMMON, D. R., MITCHELL, G. S., AND DEKIN, M. S. Glutamate, GABA, and serotonin. in ventilatory control. In: Lung Biology in Health and Disease: Regulation of Breathing, edited by J. A. Dempsey and A. I. Pack. New York: Marcel Dekker, 1994, vol. 79, p. 151-218.
31. MONTEAU, R., GAUTHIER, P., REGA, P., AND HILAIRE, G. Effects of N-methyl-D-aspartate (NMDA) antagonist MK-801 on breathing pattern in rats. Neurosci. Lett. 109: 134-139, 1990.
32. MORIN, A. M., HATTORI, H., WASTERLAIN, C. G., AND THOMSON, D. [3H]MK-801 binding sites in neonate rat brain. Brain Res. 487: 376-379, 1989.
33. NAKANISHI, S. Molecular diversity of glutamate receptors and implications for brain function. Science 258: 597-603, 1992.
34. NELSON, P. G., FIELDS, R. D., Yu, C., AND NEALE, E. A. Mechanisms involved in activity-dependent synapse formation in mammalian central nervous system cell cultures. J. Neurobiol. 21: 138-156, 1990.
35. NICOLL, R. A., KAUER, J. A., AND MALENKA, R. C. The current excitement in long-term potentiation. Neuron 1: 97-103, 1988.
36. PETRALIA, R. S., YOKOTANI, N., WENTHOLD, R. J. Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody. J. Neurosci. 14: 667-696, 1994.
37. PIERREFICHE, O., SCHMID, K., FOUTZ, A. S., AND DENAVIT-SAUBIE, M. Endogenous activation of NMDA and non-NMDA receptors on respiratory neurones in cat medulla. Neuropharmacology 30: 429-440, 1991.
38. POON, C.-S. Synaptic plasticity and respiratory control. In: Bioengineering Approaches to Pulmonary Physiology and Medicine, edited by Khoo, M.C.K. New York: Plenum Press, 1996, p. 93-113.
39. POON, C.-S., LI, Y., LI, S.-X., AND TONEGAWA, S. Respiratory rhythm is altered in neonatal mice with malfunctional NMDA receptors (Abstract). FASEB J. 8: A389, 1994.
40. POON, C.-S., ZHOU, Z., AND CHAMPAGNAT, J. Long-term synaptic depression in nucleus tractus solitarius of NMDAR1 knockout mice. Soc. Neurosci. Abstr. 22: 1595, 1996.
41. RABACCHI, S., BAILLY, Y., DELHAYLE-BOUCHAUD, N., AND MARIANI, J. Involvement of the N-methyl-D-aspartate (NMDA) receptor in synapse elimination during cerebellar development. Science 256: 1823-1825, 1992.
42. SALÈS, N., GHILINI, G., AND DENAVIT-SAUBIE, M. Autoradiographic localization of NMDA binding sites in brainstem cardiorespiratory areas of adult and newborn cats. Dev. Brain. Res. 75: 113-118, 1993.
43. SCHWEITZER, P., PIERREFICHE, O., FOUTZ, A. S., AND DENAVIT-SAUBIE, M. Effects of N-methyl-D-aspartate (NMDA) receptor blockade on breathing pattern in newborn cat. Dev. Brain Res. 56: 290-293, 1990.
44. SHATZ, C. J. Competitive interactions between retinal ganglion cells during prenatal development. J. Neurobiol. 21: 197-211, 1990a.
45. SHATZ, C. J. Impulse activity and patterning of connections during CNS development. Neuron 5: 745-756, 1990b.
46. SICA, A. L., SIDDIQI, A., AND PISANA, F. M. The effects of N-methyl-D-aspartate antagonism on the inspiratory activities of developing animals. Dev. Brain Res. 65: 281-283, 1992.
47. SMITH, J. C., ELLENBERGER, H. H., BALLANYI, K., RICHTER, D. W., AND FELDMAN, J. L. Pre-Bötzinger complex: a brainstem region that may generate respiratory rhythm in mammals. Science 254: 726-729, 1991.
48. SMITH, J. C. AND FELDMAN, J. L. In vitro brainstem-spinal cord preparation for study of motor systems for mammalian respiration and locomotion. J. Neurosci. Methods 21: 321-333, 1987.