A human ESC model for MLL-AF4 leukemic fusion gene reveals an impaired early hematopoietic-endothelial specification

Cell Research

Volumn 22, Issue 6, 2012, Pages 986-1002

  Bueno, Clara ^a   Montes, Rosa ^a   Melen, Gustavo J ^a   Ramos Mejia, Verónica ^a   Real, Pedro J ^a   Ayllón, Verónica ^a   Sanchez, Laura ^a   Ligero, Gertrudis ^a   Gutierrez Aranda, Iván ^a   Fernández, Agustín F ^b   Fraga, Mario F ^b,c   Moreno Gimeno, Inmaculada ^d   Burks, Deborah ^d   Del Carmen Plaza Calonge, María ^a   Rodríguez Manzaneque, Juan C ^a   Menendez, Pablo ^a  

^a UNIVERSITY OF GRANADA   (Spain)

^b DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

^c CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^d CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

Author keywords

endothelium; hematopoiesis; hemogenic precursors; hESC; MLL AF4

Indexed keywords

HOMEODOMAIN PROTEIN; MIXED LINEAGE LEUKEMIA PROTEIN; MLL AF4 FUSION PROTEIN, HUMAN; MLL-AF4 FUSION PROTEIN, HUMAN; ONCOPROTEIN; PROTEIN PRECURSOR;

ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CYTOLOGY; EMBRYONIC STEM CELL; ENDOTHELIUM CELL; GENE EXPRESSION PROFILING; GENETICS; HEMATOPOIESIS; HUMAN; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; UPREGULATION;

EMBRYONIC STEM CELLS; ENDOTHELIAL CELLS; GENE EXPRESSION PROFILING; HEMATOPOIESIS; HOMEODOMAIN PROTEINS; HUMANS; MYELOID-LYMPHOID LEUKEMIA PROTEIN; ONCOGENE PROTEINS, FUSION; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTEIN PRECURSORS; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84861897568     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2012.4     Document Type: Article

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