Aetheramides A and B, potent HIV-inhibitory depsipeptides from a myxobacterium of the new genus " Aetherobacter "

Organic Letters

Volumn 14, Issue 11, 2012, Pages 2854-2857

  Plaza, Alberto ^a   Garcia, Ronald ^a   Bifulco, Giuseppe ^b   Martinez, Javier Pablo ^c   Hüttel, Stephan ^a   Sasse, Florenz ^d   Meyerhans, Andreas ^c   Stadler, Marc ^d   Müller, Rolf ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b UNIVERSITY OF SALERNO   (Italy)

^c UNIVERSITAT POMPEU FABRA   (Spain)

^d HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AETHERAMIDE A; AETHERAMIDE B; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTINEOPLASTIC AGENT; DEPSIPEPTIDE;

ARTICLE; CELL STRAIN HCT116; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; DRUG SCREENING; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; ISOLATION AND PURIFICATION; MYXOCOCCALES; NUCLEAR MAGNETIC RESONANCE;

ANTI-HIV AGENTS; ANTINEOPLASTIC AGENTS; DEPSIPEPTIDES; DRUG SCREENING ASSAYS, ANTITUMOR; HCT116 CELLS; HIV-1; HUMANS; MOLECULAR STRUCTURE; MYXOCOCCALES; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR;

EID: 84861838031     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol3011002     Document Type: Article

References (23)

1. Rasko, D. A.; Sperandio, V. Nat. Rev. Drug Discovery 2010, 9, 117
2. Wenzel, S. C.; Müller, R. Curr. Opin. Drug Discovery Dev. 2009, 12, 220
3. Weissman, K. J.; Müller, R. Nat. Prod. Rep. 2010, 27, 1276
4. Garcia, R; Gerth, K; Stadler, M; Dogma, I. J., Jr.; Müller, R Mol. Phylogenet. Evol. 2010, 57, 878
5. Gerth, K; Steinmetz, H; Höfle, G; Jansen, R Angew. Chem., Int. Ed. 2008, 47, 600
6. Wenzel, S. C.; Müller, R Nat. Prod. Rep. 2009, 26, 1385
7. Garcia, R. O.; Krug, D.; Müller, R. Methods in Enzymology; Hopwood, D., Ed.; Academic Press: Burlington, MA, 2009; Vol. 458, Chapter 3, pp 59-91.
8. Fujii, K.; Ikai, Y.; Oka, H.; Suzuki, M.; Harada, K.-I. Anal. Chem. 1997, 69, 5146
9. Fujii, K.; Ikai, Y.; Mayumi, T.; Oka, H.; Suzuki, M.; Harada, K.-I. Anal. Chem. 1997, 69, 3346
10. Matsumori, N.; Kaneno, D.; Murata, M.; Nakamura, H.; Tachibana, K. J. Org. Chem. 1999, 64, 866
11. Bifulco, G.; Bassarello, C.; Riccio, R.; Gomez-Paloma, L. Org. Lett. 2004, 6, 1025
12. Bifulco, G.; Dambruoso, P.; Gomez-Paloma, L.; Riccio, R. Chem. Rev. 2007, 107, 3744
13. Bagno, A.; Rastrelli, F.; Saielli, G. J. Phys. Chem. A 2003, 107, 9964
14. Barone, G.; Duca, D.; Silvestri, A.; Gomez-Paloma, L.; Riccio, R.; Bifulco, G. Chem.-Eur. J. 2002, 8, 3240
15. Di Micco, S.; Chini, M. G.; Riccio, R.; Bifulco, G. J. Org. Chem. 2010, 8, 1411
16. Meissner, A.; Soerensen, O. W. Magn. Reson. Chem. 2001, 39, 49
17. Uhrin, D.; Batta, G.; Hruby, V. J.; Barlow, P. N.; Koever, K. E. J. Magn. Reson. 1998, 130, 155
18. Bax, A.; Davis, D. G. J. Magn. Reson. 1985, 63, 207
19. Plaza, A.; Bifulco, G.; Keffer, J. L.; Lloyd, J. R.; Baker, H. L.; Bewley, C. A. J. Org. Chem. 2009, 74, 504
20. Plaza, A.; Bifulco, G.; Masullo, M.; Keffer, J. L.; Collin, P. L.; Hooper, J. N. A.; Bell, L. J.; Bewley, C. A. J. Org. Chem. 2010, 75, 4344
21. Steinmetz, H.; Irschik, H.; Kunze, B.; Reichenbach, H.; Höfle, G.; Jansen, R. Chem.-Eur. J. 2007, 13, 5822
22. Hoye, T. R.; Jeffrey, C. S.; Shao, F. Nat. Protoc. 2007, 2, 2451
23. Brass, A. L.; Dykxhoorn, D. M.; Benita, Y.; Yan, N.; Engelman, A.; Xavier, R. J.; Lieberman, J. Science 2008, 319, 921