Development of a high-throughput screening-amenable assay for human poly(ADP-ribose) polymerase inhibitors

Journal of Pharmacological and Toxicological Methods

Volumn 47, Issue 3, 2002, Pages 137-141

  Brown, Janice A ^a   Marala, Ravi B ^a  

^a PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Autoribosylation; Biotinylated NAD; HTS; Methods; PARP

Indexed keywords

3 AMINOBENZAMIDINE; 8 HYDROXY 2 METHYL 4(3H) QUINAZOLINONE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; COLORIMETRY; DRUG DETERMINATION; DRUG SCREENING; IC 50; REPRODUCIBILITY; VALIDATION PROCESS;

ANIMALIA;

EID: 0036589750     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1056-8719(02)00223-X     Document Type: Article

References (14)

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