Role of conserved glycine in zinc-dependent medium chain dehydrogenase/reductase superfamily

Journal of Biological Chemistry

Volumn 287, Issue 23, 2012, Pages 19429-19439

  Tiwari, Manish Kumar ^a   Singh, Raushan Kumar ^a   Singh, Ranjitha ^a   Jeya, Marimuthu ^a   Zhao, Huimin ^b   Lee, Jung Kul ^a  

^a Konkuk University   (South Korea)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING GEOMETRIES; BOND ANGLE; COMPUTATIONAL ANALYSIS; DENSITY FUNCTIONALS; GLYCINE RESIDUES; ISOTHERMAL TITRATION CALORIMETRY; LARGE GROUPS; METAL BINDING AFFINITY; METAL-LIGAND BONDS; SCREENING STRATEGY; SITE DIRECTED MUTAGENESIS; SPECTROSCOPIC PROPERTY; WILD TYPES; ZINC BINDING; ZINC IONS;

AMINO ACIDS; BINDING ENERGY; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENZYMES; IONS; LIGANDS; MAGNETIC RESONANCE; PARAMAGNETISM; QUANTUM THEORY;

ZINC;

GLYCINE; MEDIUM CHAIN DEHYDROGENASE REDUCTASE; OXIDOREDUCTASE; UNCLASSIFIED DRUG; ZINC ION;

AMINO ACID ANALYSIS; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CATALYSIS; CONTROLLED STUDY; DENSITY FUNCTIONAL THEORY; ELECTRON SPIN RESONANCE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BINDING; ISOTHERMAL TITRATION CALORIMETRY; METAL BINDING; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MOTIF; QUANTUM MECHANICS; SITE DIRECTED MUTAGENESIS; SPECTROSCOPY; STRUCTURE ANALYSIS; WILD TYPE;

ALCOHOL DEHYDROGENASE; AMINO ACID MOTIFS; ELECTRON SPIN RESONANCE SPECTROSCOPY; FUNGAL PROTEINS; GLYCINE; MUTAGENESIS, SITE-DIRECTED; NEUROSPORA CRASSA; PROTEIN STRUCTURE, TERTIARY; ZINC;

EID: 84861722007     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.335752     Document Type: Article

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