Membrane-microdomain localization of amyloid β-precursor protein (APP) C-terminal fragments is regulated by phosphorylation of the cytoplasmic Thr668 residue

Journal of Biological Chemistry

Volumn 287, Issue 23, 2012, Pages 19715-19724

  Matsushima, Takahide ^a   Saito, Yuhki ^a   Elliott, James I ^b   Iijima Ando, Kanae ^c   Nishimura, Masaki ^d   Kimura, Nobuyuki ^e   Hata, Saori ^a   Yamamoto, Tohru ^a   Nakaya, Tadashi ^a   Suzuki, Toshiharu ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

^d SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^e NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; C-TERMINAL FRAGMENTS; CYTOPLASMIC DOMAINS; IN-VITRO; IN-VIVO; INTRACELLULAR DOMAIN; MEMBRANE ASSOCIATION; MEMBRANE LIPIDS; MEMBRANE MICRODOMAINS; MEMBRANE-BOUND; MICRODOMAIN; MOUSE BRAIN; N2A CELLS; PRECURSOR PROTEINS; SECRETASES;

AMINO ACIDS; GLYCOPROTEINS; LIPOSOMES; MAMMALS; MEMBRANES; PEPTIDES; SUBSTRATES;

PHOSPHORYLATION;

AMYLOID PRECURSOR PROTEIN; BRAIN PROTEIN; CYTOPLASM PROTEIN; GAMMA SECRETASE; LIPOSOME; PEPTIDE; THREONINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME SUBSTRATE; IN VITRO STUDY; IN VIVO STUDY; LIPID MEMBRANE; LIPID RAFT; MEMBRANE BINDING; MEMBRANE STRUCTURE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BRAIN; BRAIN CHEMISTRY; MEMBRANE MICRODOMAINS; MICE; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; TRYPTOPHAN;

EID: 84861719008     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.334847     Document Type: Article

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