Adverse effects in risk assessment: Modeling polychlorinated biphenyls and thyroid hormone disruption outcomes in animals and humans

Environmental Research

Volumn 116, Issue , 2012, Pages 74-84

  Parham, Fred ^a   Wise, Amber ^b   Axelrad, Daniel A ^c   Guyton, Kathryn Z ^d   Portier, Christopher ^e   Zeise, Lauren ^f   Thomas Zoeller, R ^g   Woodruff, Tracey J ^b  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c US Environmental Protection Agency (USEPA)   (United States)

^d U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^e CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^f CALIFORNIA ENVIRONMENTAL PROTECTION AGENCY   (United States)

^g UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

(5 10):polychlorinated biphenyls; Adverse health outcomes; Biological perturbations; Risk assessment; Thyroid hormones

Indexed keywords

POLYCHLORINATED BIPHENYL DERIVATIVE; THYROID HORMONE; THYROXINE;

ANIMAL; BIOASSAY; DOSE-RESPONSE RELATIONSHIP; EPIDEMIOLOGY; HORMONE; NUMERICAL MODEL; PCB; POLLUTION EXPOSURE; RISK ASSESSMENT; WORLD HEALTH ORGANIZATION;

ANIMAL EXPERIMENT; ARTICLE; CONCENTRATION RESPONSE; EXPOSURE; FEMALE; HORMONE BLOOD LEVEL; HUMAN; MICHAELIS MENTEN KINETICS; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; RISK ASSESSMENT; TOXICITY TESTING;

ANIMALS; BODY BURDEN; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCRINE DISRUPTORS; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL MONITORING; FEMALE; HUMANS; MALE; MODELS, BIOLOGICAL; POLYCHLORINATED BIPHENYLS; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RISK ASSESSMENT; THYROID HORMONES;

ANIMALIA;

EID: 84861685125     PISSN: 00139351     EISSN: 10960953     Source Type: Journal    
DOI: 10.1016/j.envres.2012.04.003     Document Type: Article

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