Preparation and characterization of novel trans- [PtCl2(amine)(isopropylamine)] compounds: Cytotoxic activity and apoptosis induction in ras-transformed cells

Journal of Medicinal Chemistry

Volumn 42, Issue 20, 1999, Pages 4264-4268

  Montero, Eva I ^a   Díaz, Sonia ^a   González Vadillo, Ana Ma ^a   Pérez, José M ^a   Alonso, C ^a   Navarro Ranninger, Carmen ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

PLATINUM COMPLEX;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL KILLING; CELL TRANSFORMATION; CHEMICAL MODIFICATION; COMPLEX FORMATION; CYTOTOXICITY; DRUG SYNTHESIS; LIGAND BINDING; ONCOGENE RAS; STRUCTURE ANALYSIS;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TRANSFORMED; CERCOPITHECUS AETHIOPS; CISPLATIN; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; GENES, RAS; HELA CELLS; HUMANS; INHIBITORY CONCENTRATION 50; JURKAT CELLS; ORGANOPLATINUM COMPOUNDS; TUMOR CELLS, CULTURED; VERO CELLS;

EID: 0344466805     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm991015e     Document Type: Article

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