-
1
-
-
0028816847
-
Purification and characterization of hypoxia-inducible factor 1
-
G.L. Wang, and G.L. Semenza Purification and characterization of hypoxia-inducible factor 1 J. Biol. Chem. 270 1995 1230 1237
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 1230-1237
-
-
Wang, G.L.1
Semenza, G.L.2
-
2
-
-
0035917808
-
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
-
P. Jaakkola Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation Science 292 2001 468 472
-
(2001)
Science
, vol.292
, pp. 468-472
-
-
Jaakkola, P.1
-
4
-
-
34247477207
-
Hypoxia inducible factor-2alpha in cancer
-
T. Lofstedt, E. Fredlund, L. Holmquist-Mengelbier, A. Pietras, M. Ovenberger, L. Poellinger, and S. Pahlman Hypoxia inducible factor-2alpha in cancer Cell Cycle 6 2007 919 926
-
(2007)
Cell Cycle
, vol.6
, pp. 919-926
-
-
Lofstedt, T.1
Fredlund, E.2
Holmquist-Mengelbier, L.3
Pietras, A.4
Ovenberger, M.5
Poellinger, L.6
Pahlman, S.7
-
5
-
-
31444444162
-
Integration of oxygen signaling at the consensus HRE
-
R.H. Wenger, D.P. Stiehl, and G. Camenisch Integration of oxygen signaling at the consensus HRE Sci. STKE 2005 2005 re12
-
(2005)
Sci. STKE
, vol.2005
, pp. 12
-
-
Wenger, R.H.1
Stiehl, D.P.2
Camenisch, G.3
-
6
-
-
37549037125
-
RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alpha
-
S. Galban RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alpha Mol. Cell. Biol. 28 2008 93 107
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 93-107
-
-
Galban, S.1
-
7
-
-
27744520451
-
HuR: Post-transcriptional paths to malignancy
-
I. Lopez de Silanes, A. Lal, and M. Gorospe HuR: post-transcriptional paths to malignancy RNA Biol. 2 2005 11 13
-
(2005)
RNA Biol.
, vol.2
, pp. 11-13
-
-
Lopez De Silanes, I.1
Lal, A.2
Gorospe, M.3
-
8
-
-
4143134276
-
Expression of the ELAV-like protein HuR is associated with higher tumor grade and increased cyclooxygenase-2 expression in human breast carcinoma
-
C. Denkert Expression of the ELAV-like protein HuR is associated with higher tumor grade and increased cyclooxygenase-2 expression in human breast carcinoma Clin. Cancer Res. 10 2004 5580 5586
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 5580-5586
-
-
Denkert, C.1
-
9
-
-
54049135560
-
Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype
-
K. Mazan-Mamczarz Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype Oncogene 27 2008 6151 6163
-
(2008)
Oncogene
, vol.27
, pp. 6151-6163
-
-
Mazan-Mamczarz, K.1
-
10
-
-
84655161946
-
HIF1alpha and HIF2alpha: Sibling rivalry in hypoxic tumour growth and progression
-
B. Keith, R.S. Johnson, and M.C. Simon HIF1alpha and HIF2alpha: sibling rivalry in hypoxic tumour growth and progression Nat. Rev. Cancer 12 2011 9 22
-
(2011)
Nat. Rev. Cancer
, vol.12
, pp. 9-22
-
-
Keith, B.1
Johnson, R.S.2
Simon, M.C.3
-
11
-
-
76349095132
-
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
-
G.L. Semenza Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics Oncogene 29 2010 625 634
-
(2010)
Oncogene
, vol.29
, pp. 625-634
-
-
Semenza, G.L.1
-
12
-
-
70649108815
-
Factors interacting with HIF-1alpha mRNA: Novel therapeutic targets
-
S. Galban, and M. Gorospe Factors interacting with HIF-1alpha mRNA: novel therapeutic targets Curr. Pharm. Des. 15 2009 3853 3860
-
(2009)
Curr. Pharm. Des.
, vol.15
, pp. 3853-3860
-
-
Galban, S.1
Gorospe, M.2
-
13
-
-
33745303045
-
Hypoxia signalling in cancer and approaches to enforce tumour regression
-
J. Pouyssegur, F. Dayan, and N.M. Mazure Hypoxia signalling in cancer and approaches to enforce tumour regression Nature 441 2006 437 443
-
(2006)
Nature
, vol.441
, pp. 437-443
-
-
Pouyssegur, J.1
Dayan, F.2
Mazure, N.M.3
-
14
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
G.L. Semenza Targeting HIF-1 for cancer therapy Nat. Rev. Cancer 3 2003 721 732
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
15
-
-
77952723369
-
Roles of hypoxia-inducible factor-1alpha (HIF-1alpha) versus HIF-2alpha in the survival of hepatocellular tumor spheroids
-
H. Menrad, C. Werno, T. Schmid, E. Copanaki, T. Deller, N. Dehne, and B. Brune Roles of hypoxia-inducible factor-1alpha (HIF-1alpha) versus HIF-2alpha in the survival of hepatocellular tumor spheroids Hepatology 51 2010 2183 2192
-
(2010)
Hepatology
, vol.51
, pp. 2183-2192
-
-
Menrad, H.1
Werno, C.2
Schmid, T.3
Copanaki, E.4
Deller, T.5
Dehne, N.6
Brune, B.7
-
16
-
-
33745685879
-
Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: Implications for targeting the HIF pathway
-
V.A. Carroll, and M. Ashcroft Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway Cancer Res. 66 2006 6264 6270
-
(2006)
Cancer Res.
, vol.66
, pp. 6264-6270
-
-
Carroll, V.A.1
Ashcroft, M.2
-
17
-
-
20744445650
-
Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma
-
R.R. Raval Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma Mol. Cell. Biol. 25 2005 5675 5686
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 5675-5686
-
-
Raval, R.R.1
-
18
-
-
34250021865
-
Neuron-specific inactivation of the hypoxia inducible factor 1 alpha increases brain injury in a mouse model of transient focal cerebral ischemia
-
O. Baranova, L.F. Miranda, P. Pichiule, I. Dragatsis, R.S. Johnson, and J.C. Chavez Neuron-specific inactivation of the hypoxia inducible factor 1 alpha increases brain injury in a mouse model of transient focal cerebral ischemia J. Neurosci. 27 2007 6320 6332
-
(2007)
J. Neurosci.
, vol.27
, pp. 6320-6332
-
-
Baranova, O.1
Miranda, L.F.2
Pichiule, P.3
Dragatsis, I.4
Johnson, R.S.5
Chavez, J.C.6
-
19
-
-
66049155861
-
Regulation of autophagy in human and murine cartilage: Hypoxia-inducible factor 2 suppresses chondrocyte autophagy
-
J. Bohensky, S.P. Terkhorn, T.A. Freeman, C.S. Adams, J.A. Garcia, I.M. Shapiro, and V. Srinivas Regulation of autophagy in human and murine cartilage: hypoxia-inducible factor 2 suppresses chondrocyte autophagy Arthritis Rheum. 60 2009 1406 1415
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 1406-1415
-
-
Bohensky, J.1
Terkhorn, S.P.2
Freeman, T.A.3
Adams, C.S.4
Garcia, J.A.5
Shapiro, I.M.6
Srinivas, V.7
-
20
-
-
34247219188
-
Target gene selectivity of hypoxia-inducible factor-alpha in renal cancer cells is conveyed by post-DNA-binding mechanisms
-
K.W. Lau, Y.M. Tian, R.R. Raval, P.J. Ratcliffe, and C.W. Pugh Target gene selectivity of hypoxia-inducible factor-alpha in renal cancer cells is conveyed by post-DNA-binding mechanisms Br. J. Cancer 96 2007 1284 1292
-
(2007)
Br. J. Cancer
, vol.96
, pp. 1284-1292
-
-
Lau, K.W.1
Tian, Y.M.2
Raval, R.R.3
Ratcliffe, P.J.4
Pugh, C.W.5
-
21
-
-
51049095933
-
Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha
-
M. Puppo, F. Battaglia, C. Ottaviano, S. Delfino, D. Ribatti, L. Varesio, and M.C. Bosco Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha Mol. Cancer Ther. 7 2008 1974 1984
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 1974-1984
-
-
Puppo, M.1
Battaglia, F.2
Ottaviano, C.3
Delfino, S.4
Ribatti, D.5
Varesio, L.6
Bosco, M.C.7
-
22
-
-
41249103991
-
Sphingosine kinase 1 is up-regulated during hypoxia in U87MG glioma cells. Role of hypoxia-inducible factors 1 and 2
-
V. Anelli, C.R. Gault, A.B. Cheng, and L.M. Obeid Sphingosine kinase 1 is up-regulated during hypoxia in U87MG glioma cells. Role of hypoxia-inducible factors 1 and 2 J. Biol. Chem. 283 2008 3365 3375
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 3365-3375
-
-
Anelli, V.1
Gault, C.R.2
Cheng, A.B.3
Obeid, L.M.4
-
23
-
-
79952534509
-
Opposite functions of HIF-alpha isoforms in VEGF induction by TGF-beta1 under non-hypoxic conditions
-
K.S. Chae Opposite functions of HIF-alpha isoforms in VEGF induction by TGF-beta1 under non-hypoxic conditions Oncogene 30 2011 1213 1228
-
(2011)
Oncogene
, vol.30
, pp. 1213-1228
-
-
Chae, K.S.1
-
24
-
-
79953067364
-
RNA-binding protein HuR mediates cytoprotection through stimulation of XIAP translation
-
D. Durie, S.M. Lewis, U. Liwak, M. Kisilewicz, M. Gorospe, and M. Holcik RNA-binding protein HuR mediates cytoprotection through stimulation of XIAP translation Oncogene 30 2011 1460 1469
-
(2011)
Oncogene
, vol.30
, pp. 1460-1469
-
-
Durie, D.1
Lewis, S.M.2
Liwak, U.3
Kisilewicz, M.4
Gorospe, M.5
Holcik, M.6
-
25
-
-
84857169594
-
Heat Shock Transcription Factor Hsf1 is Involved in Tumor Progression via Regulation of HIF -1 and RNA-binding Protein HuR
-
V.L. Gabai, L. Meng, G. Kim, T.A. Mills, I.J. Benjamin, and M.Y. Sherman Heat Shock Transcription Factor Hsf1 is Involved in Tumor Progression via Regulation of HIF -1 and RNA-binding Protein HuR Mol. Cell. Biol. 2012
-
(2012)
Mol. Cell. Biol.
-
-
Gabai, V.L.1
Meng, L.2
Kim, G.3
Mills, T.A.4
Benjamin, I.J.5
Sherman, M.Y.6
-
26
-
-
77953921408
-
Role of the RNA-binding protein HuR in human renal cell carcinoma
-
S. Danilin Role of the RNA-binding protein HuR in human renal cell carcinoma Carcinogenesis 31 2010 1018 1026
-
(2010)
Carcinogenesis
, vol.31
, pp. 1018-1026
-
-
Danilin, S.1
|