Synthesis of 2-[ 11C]methoxy-3,17β-O,O-bis(sulfamoyl) estradiol as a new potential PET agent for imaging of steroid sulfatase (STS) in cancers

Steroids

Volumn 77, Issue 8-9, 2012, Pages 864-870

  Wang, Min ^a   Xu, Lu ^a   Gao, Mingzhang ^a   Miller, Kathy D ^a   Sledge, George W ^a   Zheng, Qi Huang ^a  

^a INDIANA UNIVERSITY   (United States)

Author keywords

2 11C Methoxy 3,17 O,O bis(sulfamoyl)estradiol; Cancer imaging; Carbonic anhydrase II (CAII); Positron emission tomography (PET); Radiosynthesis; Steroid sulfatase (STS)

Indexed keywords

2 METHOXY 3,17BETA O,O BIS(SULFAMOYL)ESTRADIOL C 11; ESTRADIOL; RADIOPHARMACEUTICAL AGENT; STERYL SULFATASE; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; ISOTOPE LABELING; LIPOPHILICITY; METHYLATION; NEOPLASM; POSITRON EMISSION TOMOGRAPHY; PURIFICATION; SOLID PHASE EXTRACTION; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; METABOLISM; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RADIOCHEMISTRY;

ESTRADIOL; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; NEOPLASMS; POSITRON-EMISSION TOMOGRAPHY; RADIOCHEMISTRY; STERYL-SULFATASE;

EID: 84861608946     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2012.04.007     Document Type: Article

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