[11C]Dimebon, radiosynthesis and lipophilicity of a new potential PET agent for imaging of Alzheimer's disease and Huntington's disease

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 8, 2010, Pages 2529-2532

  Gao, Mingzhang ^a   Wang, Min ^a   Hutchins, Gary D ^a   Zheng, Qi Huang ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

11C Dimebon; Alzheimer's disease; Huntington's disease; Lipophilicity; Positron emission tomography (PET); Radiosynthesis

Indexed keywords

DIMEBON; DIMEBON C 11; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUNTINGTON CHOREA; ISOTOPE LABELING; LIPOPHILICITY; METHYLATION; POSITRON EMISSION TOMOGRAPHY; RADIOCHEMISTRY; REACTION ANALYSIS;

ALZHEIMER DISEASE; CARBON RADIOISOTOPES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; HUNTINGTON DISEASE; INDOLES; POSITRON-EMISSION TOMOGRAPHY;

EID: 77950067508     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.02.094     Document Type: Article

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