An improved synthesis of dopamine D2/D3 receptor radioligands [11C]fallypride and [18F]fallypride

Applied Radiation and Isotopes

Volumn 68, Issue 6, 2010, Pages 1079-1086

  Gao, Mingzhang ^a   Wang, Min ^a   Mock, Bruce H ^a   Glick Wilson, Barbara E ^a   Yoder, Karmen K ^a   Hutchins, Gary D ^a   Zheng, Qi Huang ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

11C Fallypride; 18F Fallypride; Dopamine D2 D3 receptor; Imaging; Positron emission tomography (PET)

Indexed keywords

[11C]FALLYPRIDE; BENZOIC ACID; CHEMICAL YIELDS; METHOXY; METHYL ESTERS; METHYL TRIFLATES; NUCLEOPHILIC SUBSTITUTIONS; PREPARATIVE HPLC; RADIOCHEMICAL YIELD; RADIOLIGANDS; REFERENCE STANDARD; SOLID-PHASE EXTRACTION; SPECIFIC ACTIVITY; SPECIFIC RADIOACTIVITY; STARTING MATERIALS; SYNTHETIC APPROACH;

BRAIN; ESTERS; EXTRACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LABELING; PHENOLS; POSITRONS; PURIFICATION; SYNTHESIS (CHEMICAL);

POSITRON EMISSION TOMOGRAPHY;

CARBON DIOXIDE; CARBON FALLYPRIDE C 11; CRYPTAND 2.2.2; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; FALLYPRIDE; FLUORINE FALLYPRIDE F 18; RADIOLIGAND; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; FLUORINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; ISOTOPE LABELING; METHYLATION; PHASE SEPARATION; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PURIFICATION; RADIOACTIVITY; RADIOCHEMISTRY; SOLID PHASE EXTRACTION; SUBSTITUTION REACTION;

BENZAMIDES; CARBON RADIOISOTOPES; FLUORINE RADIOISOTOPES; ISOTOPE LABELING; PYRROLIDINES; RADIOPHARMACEUTICALS; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3;

EID: 77649275427     PISSN: 09698043     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.apradiso.2009.09.071     Document Type: Article

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