Induction of proinflammatory mediators by CHI3L1 is reduced by chitin treatment: Decreased tumor metastasis in a breast cancer model

International Journal of Cancer

Volumn 131, Issue 2, 2012, Pages 377-386

  Libreros, Stephania ^a   Garcia Areas, Ramon ^a   Shibata, Yoshimi ^a   Carrio, Roberto ^b   Torroella Kouri, Marta ^b   Iragavarapu Charyulu, Vijaya ^a  

^a FLORIDA ATLANTIC UNIVERSITY   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

CCL2; chitin; chitinase 3 like 1 protein; CXCL2; immunosuppression; metastasis; MMP 9

Indexed keywords

CHITIN; CHITINASE 3 LIKE PROTEIN 1; CXCL2 CHEMOKINE; GAMMA INTERFERON; GELATINASE B; GLYCOPROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER CHEMOTHERAPY; CELL SUBPOPULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG MECHANISM; DRUG RESPONSE; GENE SILENCING; IMMUNE RESPONSE; IN VIVO STUDY; LUNG METASTASIS; MEDIATOR RELEASE; MOUSE; NONHUMAN; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SECRETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR GROWTH; UPREGULATION;

ANIMALS; CELL PROLIFERATION; CHEMOKINE CCL2; CHEMOKINE CXCL2; CHITIN; DISEASE PROGRESSION; FEMALE; GLYCOPROTEINS; INTERFERON-GAMMA; LUNG NEOPLASMS; MACROPHAGES; MAMMARY NEOPLASMS, ANIMAL; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED BALB C; NEOPLASM METASTASIS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84861606921     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.26379     Document Type: Article

References (43)

1. Coffman FD,. Chitinase 3-Like-1 (CHI3L1): a putative disease marker at the interface of proteomics and glycomics. Crit Rev Clin Lab Sci 2008; 45: 531-62.
2. Kzhyshkowska J, Gratchev A, Goerdt S,. Human chitinases and chitinase-like proteins as indicators for inflammation and cancer. Biomark Insights 2007; 2: 128-46.
3. Hakala BE, White C, Recklies AD,. Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family. J Biol Chem 1993; 268: 25803-10.
4. Rehli M, Krause SW, Andreesen R,. Molecular characterization of the gene for human cartilage gp-39 (CHI3L1), a member of the chitinase protein family and marker for late stages of macrophage differentiation. Genomics 1997; 43: 221-5.
5. Lee CG, Hartl D, Lee GR, Koller B, Matsuura H, Da Silva CA, Sohn MH, Cohn L, Homer RJ, Kozhich AA, Humbles A, Kearley J, et al. Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis. J Exp Med 2009; 206: 1149-66.
6. Lee CG, Da Silva CA, Lee JY, Hartl D, Elias JA,. Chitin regulation of immune responses: an old molecule with new roles. Curr Opin Immunol 2008; 20: 684-9.
7. Kzhyshkowska J, Mamidi S, Gratchev A, Kremmer E, Schmuttermaier C, Krusell L, Haus G, Utikal J, Schledzewski K, Scholtze J, Goerdt S,. Novel stabilin-1 interacting chitinase-like protein (SI-CLP) is up-regulated in alternatively activated macrophages and secreted via lysosomal pathway. Blood 2006; 107: 3221-8.
8. Hung K, Hayashi R, Lafond-Walker A, Lowenstein C, Pardoll D, Levitsky H,. The central role of CD4(+) T cells in the antitumor immune response. J Exp Med 1998; 188: 2357-68.
9. Nishimura T, Iwakabe K, Sekimoto M, Ohmi Y, Yahata T, Nakui M, Sato T, Habu S, Tashiro H, Sato M, Ohta A,. Distinct role of antigen-specific T helper type 1 (Th1) and Th2 cells in tumor eradication in vivo. J Exp Med 1999; 190: 617-27.
10. Corthay A, Skovseth DK, Lundin KU, Rosjo E, Omholt H, Hofgaard PO, Haraldsen G, Bogen B,. Primary antitumor immune response mediated by CD4+ T cells. Immunity 2005; 22: 371-83.
11. Chang C, Werb Z,. The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis. Trends Cell Biol 2001; 11: S37-S43.
12. Deryugina EI, Quigley JP,. Matrix metalloproteinases and tumor metastasis. Cancer Metastasis Rev 2006; 25: 9-34.
13. Balkwill F,. Chemokine biology in cancer. Semin Immunol 2003; 15: 49-55.
14. Coussens LM, Werb Z,. Inflammation and cancer. Nature 2002; 420: 860-7.
15. Owen JL, Iragavarapu-Charyulu V, Gunja-Smith Z, Herbert LM, Grosso JF, Lopez DM,. Up-regulation of matrix metalloproteinase-9 in T lymphocytes of mammary tumor bearers: role of vascular endothelial growth factor. J Immunol 2003; 171: 4340-51.
16. Owen JL, Lopez DM, Grosso JF, Guthrie KM, Herbert LM, Torroella-Kouri M, Iragavarapu-Charyulu V,. The expression of CCL2 by T lymphocytes of mammary tumor bearers: role of tumor-derived factors. Cell Immunol 2005; 235: 122-35.
17. Letuve S, Kozhich A, Arouche N, Grandsaigne M, Reed J, Dombret MC, Kiener PA, Aubier M, Coyle AJ, Pretolani M,. YKL-40 is elevated in patients with chronic obstructive pulmonary disease and activates alveolar macrophages. J Immunol 2008; 181: 5167-73.
18. Shibata Y, Metzger WJ, Myrvik QN,. Chitin particle-induced cell-mediated immunity is inhibited by soluble mannan: mannose receptor-mediated phagocytosis initiates IL-12 production. J Immunol 1997; 159: 2462-7.
19. Da Silva CA, Chalouni C, Williams A, Hartl D, Lee CG, Elias JA,. Chitin is a size-dependent regulator of macrophage TNF and IL-10 production. J Immunol 2009; 182: 3573-82.
20. Reese TA, Liang HE, Tager AM, Luster AD, Van Rooijen N, Voehringer D, Locksley RM,. Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature 2007; 447: 92-6.
21. Kogiso M, Nishiyama A, Shinohara T, Nakamura M, Mizoguchi E, Misawa Y, Guinet E, Nouri-Shirazi M, Dorey CK, Henriksen RA, Shibata Y,. Chitin particles induce size-dependent but carbohydrate-independent innate eosinophilia. J Leukoc Biol 2011; 90: 167-76.
22. Kim JB, Urban K, Cochran E, Lee S, Ang A, Rice B, Bata A, Campbell K, Coffee R, Gorodinsky A, Lu Z, Zhou H, et al. Non-invasive detection of a small number of bioluminescent cancer cells in vivo. PLoS One 2010; 5: e9364.
23. Nishiyama A, Tsuji S, Yamashita M, Henriksen RA, Myrvik QN, Shibata Y,. Phagocytosis of N-acetyl- D -glucosamine particles, a Th1 adjuvant, by RAW 264.7 cells results in MAPK activation and TNF-alpha, but not IL-10, production. Cell Immunol 2006; 239: 103-12.
24. Strong P, Clark H, Reid K,. Intranasal application of chitin microparticles down-regulates symptoms of allergic hypersensitivity to Dermatophagoides pteronyssinus and Aspergillus fumigatus in murine models of allergy. Clin Exp Allergy 2002; 32: 1794-800.
25. Torroella-Kouri M, Silvera R, Rodriguez D, Caso R, Shatry A, Opiela S, Ilkovitch D, Schwendener RA, Iragavarapu-Charyulu V, Cardentey Y, Strbo N, Lopez DM,. Identification of a subpopulation of macrophages in mammary tumor-bearing mice that are neither M1 nor M2 and are less differentiated. Cancer Res 2009; 69: 4800-9.
26. Johansen JS, Christensen IJ, Riisbro R, Greenall M, Han C, Price PA, Smith K, Brunner N, Harris AL,. High serum YKL-40 levels in patients with primary breast cancer is related to short recurrence free survival. Breast Cancer Res Treat 2003; 80: 15-21.
27. Lee CG, Elias JA,. Role of breast regression protein-39/YKL-40 in asthma and allergic responses. Allergy Asthma Immunol Res 2010; 2: 20-7.
28. Liyanage UK, Moore TT, Joo HG, Tanaka Y, Herrmann V, Doherty G, Drebin JA, Strasberg SM, Eberlein TJ, Goedegebuure PS, Linehan DC,. Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J Immunol 2002; 169: 2756-61.
29. Garcia-Tunon I, Ricote M, Ruiz AA, Fraile B, Paniagua R, Royuela M,. Influence of IFN-γ and its receptors in human breast cancer. BMC Cancer 2007; 7: 158.
30. Elsasser-Beile U, von Kleist S, Sauther W, Gallati H, Monting JS,. Impaired cytokine production in whole blood cell cultures of patients with gynaecological carcinomas in different clinical stages. Br J Cancer 1993; 68: 32-6.
31. Ling H, Recklies AD,. The chitinase 3-like protein human cartilage glycoprotein 39 inhibits cellular responses to the inflammatory cytokines interleukin-1 and tumour necrosis factor-α. Biochem J 2004; 380: 651-9.
32. Shao R, Hamel K, Petersen L, Cao QJ, Arenas RB, Bigelow C, Bentley B, Yan W,. YKL-40, a secreted glycoprotein, promotes tumor angiogenesis. Oncogene 2009; 28: 4456-68.
33. Liu X, Das AM, Seideman J, Griswold D, Afuh CN, Kobayashi T, Abe S, Fang Q, Hashimoto M, Kim H, Wang X, Shen L, et al. The CC chemokine ligand 2 (CCL2) mediates fibroblast survival through IL-6. Am J Respir Cell Mol Biol 2007; 37: 121-8.
34. Wickremasinghe MI, Thomas LH, O'Kane CM, Uddin J, Friedland JS,. Transcriptional mechanisms regulating alveolar epithelial cell-specific CCL5 secretion in pulmonary tuberculosis. J Biol Chem 2004; 279: 27199-210.
35. Cousens LP, Orange JS, Su HC, Biron CA,. Interferon-α/β inhibition of interleukin 12 and interferon-γ production in vitro and endogenously during viral infection. Proc Natl Acad Sci USA 1997; 94: 634-9.
36. Faibish M, Francescone R, Bentley B, Yan W, Shao R,. A YKL-40-neutralizing antibody blocks tumor angiogenesis and progression: a potential therapeutic agent in cancers. Mol Cancer Ther 2011; 10: 742-51.
37. Ober C, Chupp GL,. The chitinase and chitinase-like proteins: a review of genetic and functional studies in asthma and immune-mediated diseases. Curr Opin Allergy Clin Immunol 2009; 9: 401-8.
38. Lee CG, Da Silva CA, Dela Cruz CS, Ahangari F, Ma B, Kang MJ, He CH, Takyar S, Elias JA,. Role of chitin and chitinase/chitinase-like proteins in inflammation, tissue remodeling, and injury. Annu Rev Physiol 2011; 73: 479-501.
39. Shibata Y, Foster LA, Metzger WJ, Myrvik QN,. Alveolar macrophage priming by intravenous administration of chitin particles, polymers of N-acetyl- D -glucosamine, in mice. Infect Immun 1997; 65: 1734-41.
40. Shibata Y, Foster LA, Bradfield JF, Myrvik QN,. Oral administration of chitin down-regulates serum IgE levels and lung eosinophilia in the allergic mouse. J Immunol 2000; 164: 1314-21.
41. Shibata Y, Foster LA, Kurimoto M, Okamura H, Nakamura RM, Kawajiri K, Justice JP, Van Scott MR, Myrvik QN, Metzger WJ,. Immunoregulatory roles of IL-10 in innate immunity: IL-10 inhibits macrophage production of IFN-γ-inducing factors but enhances NK cell production of IFN-γ. J Immunol 1998; 161: 4283-8.
42. Suzuki S, Okawa Y, Okura Y, Hashimoto K, Suzuki M,. Immunoadjuvant effect of chitin and chitosan. In:, Hirano S, Tokura S, editors, eds. Chitin and chitosan. Sapporo: Japan Soc Chitin Chitosan, 1982. 210-12.
43. Bergers G, Brekken R, McMahon G, Vu TH, Itoh T, Tamaki K, Tanzawa K, Thorpe P, Itohara S, Werb Z, Hanahan D,. Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nat Cell Biol 2000; 2: 737-44.