메뉴 건너뛰기




Volumn 10, Issue 5, 2011, Pages 742-751

A YKL-40-neutralizing antibody blocks tumor angiogenesis and progression: A potential therapeutic agent in cancers

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY YKL 4; NEUTRALIZING ANTIBODY; PROTEIN KINASE B; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2;

EID: 79956057857     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-10-0868     Document Type: Article
Times cited : (147)

References (43)
  • 1
    • 0026773679 scopus 로고
    • Identification of proteins secreted by human osteoblastic cells in culture
    • Johansen JS, Williamson MK, Rice JS, Price PA. Identification of proteins secreted by human osteoblastic cells in culture. J Bone Mine Res 1992;7:501-12.
    • (1992) J Bone Mine Res , vol.7 , pp. 501-512
    • Johansen, J.S.1    Williamson, M.K.2    Rice, J.S.3    Price, P.A.4
  • 2
    • 0032518453 scopus 로고    scopus 로고
    • Chitotriosidase a chitinase, and the 39-kDa human cartilage glycoprotein, a chitin-binding lectin, are homologues of family 18 glycosyl hydrolases secreted by human macrophages
    • DOI 10.1046/j.1432-1327.1998.2510504.x
    • Renkema GH, Boot RG, Au FL, Donker-Koopman WE, Strijland A, Muijsers AO, et al. Chitotriosidase, a chitinase, and the 39-kDa human cartilage glycoprotein, a chitin-binding lectin, are homologues of family 18 glycosyl hydrolases secreted by human macrophages. Eur J Biochem 1998;251:504-9. (Pubitemid 28080953)
    • (1998) European Journal of Biochemistry , vol.251 , Issue.1-2 , pp. 504-509
    • Renkema, G.H.1    Boot, R.G.2    Au, F.L.3    Donker-Koopman, W.E.4    Strijland, A.5    Muijsers, A.O.6    Hrebicek, M.7    Aerts, J.M.F.G.8
  • 3
    • 0141621106 scopus 로고    scopus 로고
    • Crystal structure and carbohydrate-binding properties of the human cartilage glycoprotein-39
    • DOI 10.1074/jbc.M303137200
    • Fusetti F, Pijning T, Kalk KH, Bos E, Dijkstra BW. Crystal structure and carbohydrate-binding properties of the human cartilage glycoprotein-39. J Biol Chem 2003;278:37753-60. (Pubitemid 37175301)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.39 , pp. 37753-37760
    • Fusetti, F.1    Pijning, T.2    Kalk, K.H.3    Bos, E.4    Dijkstra, B.W.5
  • 4
    • 0036645699 scopus 로고    scopus 로고
    • The chitinase 3-like protein human cartilage glycoprotein 39 (HC-gp39) stimulates proliferation of human connective-tissue cells and activates both extracellular signal-regulated kinase- And protein kinase B-mediated signalling pathways
    • DOI 10.1042/BJ20020075
    • Recklies AD, White C, Ling H. The chitinase 3-like protein human cartilage glycoprotein 39 (HC-gp39) stimulates proliferation of human connective-tissue cells and activates both extracellular signal-regulated kinase- and protein kinase B-mediated signalling pathways. Biochem J 2002;365:119-26. (Pubitemid 34756146)
    • (2002) Biochemical Journal , vol.365 , Issue.1 , pp. 119-126
    • Recklies, A.D.1    White, C.2    Ling, H.3
  • 5
    • 0034806471 scopus 로고    scopus 로고
    • YKL-40 (cartilage gp-39) induces proliferative events in cultured chondrocytes and synoviocytes and increases glycosaminoglycan synthesis in chondrocytes
    • DOI 10.1006/bbrc.2001.5253
    • De Ceuninck F, Gaufillier S, Bonnaud A, Sabatini M, Lesur C, Pastoureau P. YKL-40 (cartilage gp-39) induces proliferative events in cultured chondrocytes and synoviocytes and increases glycosaminoglycan synthesis in chondrocytes. Biochem Bioph Res Co 2001;285:926-31. (Pubitemid 32918025)
    • (2001) Biochemical and Biophysical Research Communications , vol.285 , Issue.4 , pp. 926-931
    • De Ceuninck, F.1    Gaufillier, S.2    Bonnaud, A.3    Sabatini, M.4    Lesur, C.5    Pastoureau, P.6
  • 6
    • 0033542726 scopus 로고    scopus 로고
    • Gp38k, a protein synthesized by vascular smooth muscle cells, stimulates directional migration of human umbilical vein endothelial cells
    • DOI 10.1006/excr.1999.4511
    • Malinda KM, Ponce L, Kleinman HK, Shackelton LM, Millis AJ. Gp38k, a protein synthesized by vascular smooth muscle cells, stimulates directional migration of human umbilical vein endothelial cells. Exp Cell Res 1999;250:168-73. (Pubitemid 29391580)
    • (1999) Experimental Cell Research , vol.250 , Issue.1 , pp. 168-173
    • Malinda, K.M.1    Ponce, L.2    Kleinman, H.K.3    Shackelton, L.M.4    Millis, A.J.T.5
  • 7
    • 33646180025 scopus 로고    scopus 로고
    • Serum cartilage oligomeric matrix protein and other biomarker profiles in tibiofemoral and patellofemoral osteoarthritis of the knee
    • see comment
    • Sharif M, Granell R, Johansen J, Clarke S, Elson C, Kirwan JR. Serum cartilage oligomeric matrix protein and other biomarker profiles in tibiofemoral and patellofemoral osteoarthritis of the knee [see comment]. Rheumatology 2006;45:522-6.
    • (2006) Rheumatology , vol.45 , pp. 522-526
    • Sharif, M.1    Granell, R.2    Johansen, J.3    Clarke, S.4    Elson, C.5    Kirwan, J.R.6
  • 9
    • 33646842919 scopus 로고    scopus 로고
    • Studies on serum YKL-40 as a biomarker in diseases with inflammation, tissue remodelling, fibroses and cancer
    • Johansen JS. Studies on serum YKL-40 as a biomarker in diseases with inflammation, tissue remodelling, fibroses and cancer. Dan Med Bul 2006;53:172-209. (Pubitemid 43772025)
    • (2006) Danish Medical Bulletin , vol.53 , Issue.2 , pp. 172-209
    • Johansen, J.S.1
  • 10
    • 0032704645 scopus 로고    scopus 로고
    • YKL-40, a matrix protein of specific granules in neutrophils, is elevated in serum of patients with community-acquired pneumonia requiring hospitalization
    • DOI 10.1086/315050
    • Nordenbaek C, Johansen JS, Junker P, Borregaard N, Sorensen O, Price PA. YKL-40, a matrix protein of specific granules in neutrophils, is elevated in serum of patients with community-acquired pneumonia requiring hospitalization. J Infect Dis 1999;180:1722-6. (Pubitemid 29506483)
    • (1999) Journal of Infectious Diseases , vol.180 , Issue.5 , pp. 1722-1726
    • Nordenbaek, C.1    Johansen, J.S.2    Junker, P.3    Borregaard, N.4    Sorensen, O.5    Price, P.A.6
  • 11
    • 33644518424 scopus 로고    scopus 로고
    • Clusterin plays an important role in hepatocellular carcinoma metastasis
    • Lau SH, Sham JS, Xie D, Tzang CH, Tang D, Ma N, et al. Clusterin plays an important role in hepatocellular carcinoma metastasis. Oncogene 2006;25:1242-50.
    • (2006) Oncogene , vol.25 , pp. 1242-1250
    • Lau, S.H.1    Sham, J.S.2    Xie, D.3    Tzang, C.H.4    Tang, D.5    Ma, N.6
  • 14
    • 0141960434 scopus 로고    scopus 로고
    • High levels of serum HER-2/neu and YKL-40 independently reflect aggressiveness of metastatic breast cancer
    • Jensen BV, Johansen JS, Price PA. High levels of serum HER-2/neu and YKL-40 independently reflect aggressiveness of metastatic breast cancer. Clin Cancer Res 2003;9:4423-34. (Pubitemid 37248400)
    • (2003) Clinical Cancer Research , vol.9 , Issue.12 , pp. 4423-4434
    • Jensen, B.V.1    Johansen, J.S.2    Price, P.A.3
  • 17
    • 1242312462 scopus 로고    scopus 로고
    • High plasma YKL-40 level in patients with ovarian cancer stage III is related to shorter survival
    • Hogdall EV, Johansen JS, Kjaer SK, Price PA, Christensen L, Blaakaer J, et al. High plasma YKL-40 level in patients with ovarian cancer stage III is related to shorter survival. Oncol Rep 2003;10:1535-8.
    • (2003) Oncol Rep , vol.10 , pp. 1535-1538
    • Hogdall, E.V.1    Johansen, J.S.2    Kjaer, S.K.3    Price, P.A.4    Christensen, L.5    Blaakaer, J.6
  • 20
    • 0036488496 scopus 로고    scopus 로고
    • Specialization of tumour vasculature
    • Ruoslahti E. Specialization of tumour vasculature. Nat Rev Cancer 2002;2:83-90.
    • (2002) Nat Rev Cancer , vol.2 , pp. 83-90
    • Ruoslahti, E.1
  • 21
    • 0036782278 scopus 로고    scopus 로고
    • VEGF and the quest for tumour angiogenesis factors
    • Ferrara N. VEGF and the quest for tumour angiogenesis factors. Nat Rev Cancer 2002;2:795-803.
    • (2002) Nat Rev Cancer , vol.2 , pp. 795-803
    • Ferrara, N.1
  • 22
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 23
    • 41649112610 scopus 로고    scopus 로고
    • Bevacizumab for recurrent malignant gliomas: Efficacy, toxicity, and patterns of recurrence
    • Norden AD, Young GS, Setayesh K, Muzikansky A, Klufas R, Ross GL, et al. Bevacizumab for recurrent malignant gliomas: efficacy, toxicity, and patterns of recurrence. Neurology 2008;70:779-87.
    • (2008) Neurology , vol.70 , pp. 779-787
    • Norden, A.D.1    Young, G.S.2    Setayesh, K.3    Muzikansky, A.4    Klufas, R.5    Ross, G.L.6
  • 24
    • 0042343801 scopus 로고    scopus 로고
    • A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
    • Yang JC, Haworth L, Sherry RM, Hwu P, Schwartzentruber DJ, Topalian SL, et al. A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. New Engl J Med 2003;349:427-34.
    • (2003) New Engl J Med , vol.349 , pp. 427-434
    • Yang, J.C.1    Haworth, L.2    Sherry, R.M.3    Hwu, P.4    Schwartzentruber, D.J.5    Topalian, S.L.6
  • 25
    • 60649116273 scopus 로고    scopus 로고
    • Antiangiogenic therapy using bevacizumab in recurrent high-grade glioma: Impact on local control and patient survival
    • Narayana A, Kelly P, Golfinos J, Parker E, Johnson G, Knopp E, et al. Antiangiogenic therapy using bevacizumab in recurrent high-grade glioma: impact on local control and patient survival. J Neurosurg 2009;110:173-80.
    • (2009) J Neurosurg , vol.110 , pp. 173-180
    • Narayana, A.1    Kelly, P.2    Golfinos, J.3    Parker, E.4    Johnson, G.5    Knopp, E.6
  • 26
    • 3843067664 scopus 로고    scopus 로고
    • Human microvascular endothelial cells immortalized with human telomerase catalytic protein: A model for the study of in vitro angiogenesis
    • Shao R, Guo X. Human microvascular endothelial cells immortalized with human telomerase catalytic protein: a model for the study of in vitro angiogenesis. Biochem Bioph Res Co 2004;321:788-94.
    • (2004) Biochem Bioph Res Co , vol.321 , pp. 788-794
    • Shao, R.1    Guo, X.2
  • 27
    • 48249099239 scopus 로고    scopus 로고
    • Distinct angiogenic mediators are required for basic fibroblast growth factor- and vascular endothelial growth factor-induced angiogenesis: The role of cytoplasmic tyrosine kinase c-Abl in tumor angiogenesis
    • Yan W, Bentley B, Shao R. Distinct angiogenic mediators are required for basic fibroblast growth factor- and vascular endothelial growth factor-induced angiogenesis: the role of cytoplasmic tyrosine kinase c-Abl in tumor angiogenesis. Mol Biol Cell 2008;19:2278-88.
    • (2008) Mol Biol Cell , vol.19 , pp. 2278-2288
    • Yan, W.1    Bentley, B.2    Shao, R.3
  • 30
    • 60649106195 scopus 로고    scopus 로고
    • Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis
    • see comment
    • Paez-Ribes M, Allen E, Hudock J, Akeda T, Okuyama H, Vinals F, et al. Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis [see comment]. Cancer Cell 2009;15:220-31.
    • (2009) Cancer Cell , vol.15 , pp. 220-231
    • Paez-Ribes, M.1    Allen, E.2    Hudock, J.3    Akeda, T.4    Okuyama, H.5    Vinals, F.6
  • 32
    • 66049139534 scopus 로고    scopus 로고
    • Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis
    • Lee CG, Hartl D, Lee GR, Koller B, Matsuura H, Da Silva CA, et al. Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis. J Exp Med 2009;206:1149-66.
    • (2009) J Exp Med , vol.206 , pp. 1149-1166
    • Lee, C.G.1    Hartl, D.2    Lee, G.R.3    Koller, B.4    Matsuura, H.5    Da Silva, C.A.6
  • 33
    • 0031571093 scopus 로고    scopus 로고
    • Molecular characterization of the gene for human cartilage gp-39 (CHI3L1), a member of the chitinase protein family and marker for late stages of macrophage differentiation
    • Rehli M, Krause SW, Andreesen R. Molecular characterization of the gene for human cartilage gp-39 (CHI3L1), a member of the chitinase protein family and marker for late stages of macrophage differentiation. Genomics 1997;43:221-5.
    • (1997) Genomics , vol.43 , pp. 221-225
    • Rehli, M.1    Krause, S.W.2    Andreesen, R.3
  • 34
    • 79955416050 scopus 로고    scopus 로고
    • Role of YKL-40 in the angiogenesis, radioresistance, and progression of glioblastoma
    • Epub ahead of print
    • Francescone RA, Scully S, Faibish M, Taylor SL, Oh D, Moral L, et al. Role of YKL-40 in the angiogenesis, radioresistance, and progression of glioblastoma. J Biol Chem 2011 [Epub ahead of print].
    • (2011) J Biol Chem
    • Francescone, R.A.1    Scully, S.2    Faibish, M.3    Taylor, S.L.4    Oh, D.5    Moral, L.6
  • 36
    • 5644236459 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway
    • Qiao M, Shapiro P, Kumar R, Passaniti A. Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway. J Biol Chem 2004;279:42709-18.
    • (2004) J Biol Chem , vol.279 , pp. 42709-42718
    • Qiao, M.1    Shapiro, P.2    Kumar, R.3    Passaniti, A.4
  • 37
    • 52449120635 scopus 로고    scopus 로고
    • Synthetic activation of endogenous PI3K and Rac identifies an and-gate switch for cell polarization and migration
    • Inoue T, Meyer T. Synthetic activation of endogenous PI3K and Rac identifies an AND-gate switch for cell polarization and migration. PLoS One 2008;3:e3068.
    • (2008) PLoS One , vol.3
    • Inoue, T.1    Meyer, T.2
  • 38
    • 17744375604 scopus 로고    scopus 로고
    • Regulation of YKL-40 expression during genotoxic or microenvironmental stress in human glioblastoma cells
    • Junker N, Johansen JS, Hansen LT, Lund EL, Kristjansen PE. Regulation of YKL-40 expression during genotoxic or microenvironmental stress in human glioblastoma cells. Cancer Sci 2005;96:183-90.
    • (2005) Cancer Sci , vol.96 , pp. 183-190
    • Junker, N.1    Johansen, J.S.2    Hansen, L.T.3    Lund, E.L.4    Kristjansen, P.E.5
  • 39
    • 0037967272 scopus 로고    scopus 로고
    • Tumorigenesis and the angiogenic switch
    • Bergers G, Benjamin LE. Tumorigenesis and the angiogenic switch. Nat Rev Cancer 2003;3:401-10.
    • (2003) Nat Rev Cancer , vol.3 , pp. 401-410
    • Bergers, G.1    Benjamin, L.E.2
  • 40
    • 42949148257 scopus 로고    scopus 로고
    • Phase II study of sunitinib malate, an oral multitargeted tyrosine kinase inhibitor, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane
    • Burstein HJ, Elias AD, Rugo HS, Cobleigh MA, Wolff AC, Eisenberg PD, et al. Phase II study of sunitinib malate, an oral multitargeted tyrosine kinase inhibitor, in patients with metastatic breast cancer previously treated with an anthracycline and a taxane. J Clin Oncol 2008;26:1810-6.
    • (2008) J Clin Oncol , vol.26 , pp. 1810-1816
    • Burstein, H.J.1    Elias, A.D.2    Rugo, H.S.3    Cobleigh, M.A.4    Wolff, A.C.5    Eisenberg, P.D.6
  • 42
    • 26644471951 scopus 로고    scopus 로고
    • Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
    • Casanovas O, Hicklin DJ, Bergers G, Hanahan D. Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors. Cancer Cell 2005;8:299-309.
    • (2005) Cancer Cell , vol.8 , pp. 299-309
    • Casanovas, O.1    Hicklin, D.J.2    Bergers, G.3    Hanahan, D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.