MAPK/ERK-dependent translation factor hyperactivation and dysregulated laminin γ2 expression in oral dysplasia and squamous cell carcinoma

American Journal of Pathology

Volumn 180, Issue 6, 2012, Pages 2462-2478

  Degen, Martin ^a   Natarajan, Easwar ^b   Barron, Patricia ^a   Widlund, Hans R ^a   Rheinwald, James G ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; INITIATION FACTOR; INITIATION FACTOR 4B; LAMININ; LAMININ GAMMA2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; PROTEIN E6; PROTEIN S6; RAF PROTEIN; UNCLASSIFIED DRUG;

5' UNTRANSLATED REGION; ADULT; AGED; ARTICLE; BASAL CELL; CARCINOMA CELL; CELL CULTURE; CELL DENSITY; CONTROLLED STUDY; DYSPLASIA; FEMALE; GENE OVEREXPRESSION; GENE REPRESSION; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING; MALE; MOUTH DYSPLASIA; MOUTH SQUAMOUS CELL CARCINOMA; NEWBORN; ONCOGENE H RAS; POLYMERASE CHAIN REACTION; PRECANCER; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSLATION INITIATION;

CARCINOMA, SQUAMOUS CELL; DISEASE PROGRESSION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KERATINOCYTES; LAMININ; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MOUTH NEOPLASMS; NEOPLASM PROTEINS; PRECANCEROUS CONDITIONS; PROTEIN MODIFICATION, TRANSLATIONAL; RAF KINASES; RAS PROTEINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

EID: 84861593760     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.02.028     Document Type: Article

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