A novel vasculo-angiogenic effect of cilostazol mediated by cross-talk between multiple signalling pathways including the ERK/p38 MAPK signalling transduction cascade

Clinical Science

Volumn 123, Issue 3, 2012, Pages 147-159

  Chao, Ting Hsing ^a,b   Tseng, Shih Ya ^a,c   Li, Yi Heng ^a   Liu, Ping Yen ^a   Cho, Chung Lung ^c   Shi, Guey Yueh ^a   Wu, Hua Lin ^a   Chen, Jyh Hong ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY HOSPITAL   (Taiwan)

^c NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

Angiogenesis; Cilostazol; Endothelial cells; Endothelial progenitor cell (EPC); Ischaemia; Vasculogenesis

Indexed keywords

CILOSTAZOL; CYCLIC AMP DEPENDENT PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; CD34 ANTIGEN; COLLAGEN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; LAMININ; MATRIGEL; NITRIC OXIDE; NOS3 PROTEIN, HUMAN; PROTEIN KINASE B; PROTEOGLYCAN; TETRAZOLE DERIVATIVE;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD FLOW; CAPILLARY DENSITY; CD34 SELECTION; CELL MIGRATION; CELL PROLIFERATION; CHEMOTAXIS; COLONY FORMATION; CONTROLLED STUDY; DOWNSTREAM PROCESSING; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIAL PROGENITOR CELL; HINDLIMB; HUMAN; HUMAN CELL; LIMB ISCHEMIA; MALE; MOLECULAR INTERACTION; MOUSE; MUSCLE ISCHEMIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; ANIMAL; APOPTOSIS; BIOSYNTHESIS; BLOOD VESSEL; CELL MOTION; CLONOGENIC ASSAY; CYTOLOGY; DRUG COMBINATION; ENZYMOLOGY; ISCHEMIA; METABOLISM; PATHOLOGY; PHOSPHORYLATION; STEM CELL; VASCULARIZATION;

ANIMALS; ANTIGENS, CD34; APOPTOSIS; BLOOD VESSELS; CELL MOVEMENT; CELL PROLIFERATION; COLLAGEN; COLONY-FORMING UNITS ASSAY; DRUG COMBINATIONS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HINDLIMB; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; ISCHEMIA; LAMININ; MAP KINASE SIGNALING SYSTEM; MICE; NEOVASCULARIZATION, PHYSIOLOGIC; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEOGLYCANS; PROTO-ONCOGENE PROTEINS C-AKT; STEM CELLS; TETRAZOLES; UP-REGULATION;

EID: 84861568324     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20110432     Document Type: Article

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