Signal transducer and activator of transcription 3 (STAT3) protein suppresses adenoma-to-carcinoma transition in Apcmin/+ mice via regulation of Snail-1 (SNAI) protein stability

Journal of Biological Chemistry

Volumn 287, Issue 22, 2012, Pages 18182-18189

  Lee, Jongdae ^a,b   Kim, Joanna C K ^a   Lee, Shee Eun ^a,c   Quinley, Christine ^a   Kim, HyeRi ^a   Herdman, Scott ^a   Corr, Maripat ^a   Raz, Eyal ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b Chonnam National University ^*  (United States)

^c Chonnam National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; DISEASES; MAMMALS; MOLLUSCS; PROTEINS; TRANSCRIPTION;

COLORECTAL CANCER CELL; EPITHELIAL-MESENCHYMAL TRANSITION; EXPRESSION LEVELS; GLYCOGEN SYNTHASE KINASE; INTESTINAL EPITHELIAL CELLS; PROTEIN STABILITY; SIGNAL TRANSDUCERS; TUMOR INVASION;

TUMORS;

ADAPTOR PROTEIN; APC PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; PROTEIN SNAIL 1; STAT3 PROTEIN; TRANSCRIPTION FACTOR SNAIL; UNCLASSIFIED DRUG;

ADENOMA TO CARCINOMA TRANSITION; ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CANCER INVASION; CELL TRANSFORMATION; COLON CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; IN VITRO STUDY; IN VIVO STUDY; INTESTINE EPITHELIUM; INTESTINE TUMOR; KNOCKOUT MOUSE; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; PROTEIN SYNTHESIS INHIBITION; REGULATORY MECHANISM;

GASTROPODA; MUS;

EID: 84861567294     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.328831     Document Type: Article

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