Aβ-40 Y10F increases βfibrils formation but attenuates the neurotoxicity of amyloid-β peptide

International Journal of Molecular Sciences

Volumn 13, Issue 5, 2012, Pages 5324-5337

  Dai, Xueling ^a,b   Chang, Ping ^b   Liu, Wenjuan ^b   Xu, Ke ^c   Sun, Yaxuan ^b   Zhu, Shigong ^a   Jiang, Zhaofeng ^b  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b BEIJING UNION UNIVERSITY   (China)

^c CAPITAL NORMAL UNIVERSITY   (China)

Author keywords

fibrils; Alzheimer's disease; Amyloid ; Neurotoxicity; Peptide

Indexed keywords

AMYLOID BETA PROTEIN; HYDROGEN PEROXIDE; PHENYLALANINE; THIOFLAVINE; TYROSINE; AMYLOID BETA PROTEIN[1-40]; PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; ANIMAL TISSUE; ARTICLE; BETA SHEET; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; EMBRYO; HYDROPHOBICITY; NEUROTOXICITY; NONHUMAN; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN CROSS LINKING; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; RADICAL REACTION; RAT; RESIDUE ANALYSIS; SENILE PLAQUE; STRUCTURE ANALYSIS; SUBSTITUTION REACTION; ANIMAL; CELL CULTURE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; NERVE CELL; PATHOLOGY; PROTEINOSIS; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE;

ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; AMYLOID BETA-PEPTIDES; ANIMALS; CELLS, CULTURED; HUMANS; HYDROGEN PEROXIDE; NEURONS; PEPTIDE FRAGMENTS; PHENYLALANINE; PROTEIN AGGREGATION, PATHOLOGICAL; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RATS, SPRAGUE-DAWLEY; TYROSINE;

EID: 84861563553     PISSN: None     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms13055324     Document Type: Article

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