-
1
-
-
0036718611
-
Comparative analyses of immunoglobulin genes: Surprises and portents
-
Flajnik, M.F. 2002. Comparative analyses of immunoglobulin genes: surprises and portents. Nat. Rev. Immunol. 2:688-698.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 688-698
-
-
Flajnik, M.F.1
-
2
-
-
3242888974
-
V(D)J recombination
-
Schatz, D.G. 2004. V(D)J recombination. Immunol. Rev. 200:5-11.
-
(2004)
Immunol. Rev.
, vol.200
, pp. 5-11
-
-
Schatz, D.G.1
-
3
-
-
0034264851
-
Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the hyper-IgM syndrome (HIGM2)
-
Revy, P., T. Muto, Y. Levy, F. Geissmann, A. Plebani, O. Sanal, N. Catalan, M. Forveille, R. Dufourcq-Labelouse, A. Gennery, et al. 2000. Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the hyper-IgM syndrome (HIGM2). Cell. 102:565-575.
-
(2000)
Cell
, vol.102
, pp. 565-575
-
-
Revy, P.1
Muto, T.2
Levy, Y.3
Geissmann, F.4
Plebani, A.5
Sanal, O.6
Catalan, N.7
Forveille, M.8
Dufourcq-Labelouse, R.9
Gennery, A.10
-
4
-
-
0034268780
-
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
-
Muramatsu, M., K. Kinoshita, S. Fagarasan, S. Yamada, Y. Shinkai, and T. Honjo. 2000. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell. 102:553-563.
-
(2000)
Cell
, vol.102
, pp. 553-563
-
-
Muramatsu, M.1
Kinoshita, K.2
Fagarasan, S.3
Yamada, S.4
Shinkai, Y.5
Honjo, T.6
-
5
-
-
1842319924
-
Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch
-
Kataoka, T., T. Kawakami, N. Takahashi, and T. Honjo. 1980. Rearrangement of immunoglobulin gamma 1-chain gene and mechanism for heavy-chain class switch. Proc. Natl. Acad. Sci. USA. 77:919-923.
-
(1980)
Proc. Natl. Acad. Sci. USA
, vol.77
, pp. 919-923
-
-
Kataoka, T.1
Kawakami, T.2
Takahashi, N.3
Honjo, T.4
-
6
-
-
7444271524
-
Evolution of isotype switching
-
Stavnezer, J., and C.T. Amemiya. 2004. Evolution of isotype switching. Semin. Immunol. 16:257-275.
-
(2004)
Semin. Immunol.
, vol.16
, pp. 257-275
-
-
Stavnezer, J.1
Amemiya, C.T.2
-
7
-
-
0037076967
-
AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts
-
Yoshikawa, K., I.M. Okazaki, T. Eto, K. Kinoshita, M. Muramatsu, H. Nagaoka, and T. Honjo. 2002. AID enzyme-induced hypermutation in an actively transcribed gene in fibroblasts. Science. 296:2033-2036.
-
(2002)
Science
, vol.296
, pp. 2033-2036
-
-
Yoshikawa, K.1
Okazaki, I.M.2
Eto, T.3
Kinoshita, K.4
Muramatsu, M.5
Nagaoka, H.6
Honjo, T.7
-
8
-
-
0037149473
-
The AID enzyme induces class switch recombination in fibroblasts
-
Okazaki, I.M., K. Kinoshita, M. Muramatsu, K. Yoshikawa, and T. Honjo. 2002. The AID enzyme induces class switch recombination in fibroblasts. Nature. 416:340-345.
-
(2002)
Nature
, vol.416
, pp. 340-345
-
-
Okazaki, I.M.1
Kinoshita, K.2
Muramatsu, M.3
Yoshikawa, K.4
Honjo, T.5
-
9
-
-
0032101611
-
Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein
-
Phung, Q.H., D.B. Winter, A. Cranston, R.E. Tarone, V.A. Bohr, R. Fishel, and P.J. Gearhart. 1998. Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein. J. Exp. Med. 187:1745-1751.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1745-1751
-
-
Phung, Q.H.1
Winter, D.B.2
Cranston, A.3
Tarone, R.E.4
Bohr, V.A.5
Fishel, R.6
Gearhart, P.J.7
-
10
-
-
6344256944
-
Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation
-
Rada, C., J.M. Di Noia, and M.S. Neuberger. 2004. Mismatch recognition and uracil excision provide complementary paths to both Ig switching and the A/T-focused phase of somatic mutation. Mol. Cell. 16:163-171.
-
(2004)
Mol. Cell
, vol.16
, pp. 163-171
-
-
Rada, C.1
Di Noia, J.M.2
Neuberger, M.S.3
-
11
-
-
0033517129
-
Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes
-
Schrader, C.E., W. Edelmann, R. Kucherlapati, and J. Stavnezer. 1999. Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes. J. Exp. Med. 190:323-330.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 323-330
-
-
Schrader, C.E.1
Edelmann, W.2
Kucherlapati, R.3
Stavnezer, J.4
-
12
-
-
0034614916
-
Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern
-
Wiesendanger, M., B. Kneitz, W. Edelmann, and M.D. Scharff. 2000. Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern. J. Exp. Med. 191:579-584.
-
(2000)
J. Exp. Med.
, vol.191
, pp. 579-584
-
-
Wiesendanger, M.1
Kneitz, B.2
Edelmann, W.3
Scharff, M.D.4
-
13
-
-
0037019315
-
AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification
-
Petersen-Mahrt, S.K., R.S. Harris, and M.S. Neuberger. 2002. AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. Nature. 418:99-103.
-
(2002)
Nature
, vol.418
, pp. 99-103
-
-
Petersen-Mahrt, S.K.1
Harris, R.S.2
Neuberger, M.S.3
-
14
-
-
0037866984
-
H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation
-
Reina-San-Martin, B., S. Difilippantonio, L. Hanitsch, R.F. Masilamani, A. Nussenzweig, and M.C. Nussenzweig. 2003. H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation. J. Exp. Med. 197:1767-1778.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1767-1778
-
-
Reina-San-Martin, B.1
Difilippantonio, S.2
Hanitsch, L.3
Masilamani, R.F.4
Nussenzweig, A.5
Nussenzweig, M.C.6
-
15
-
-
8644238314
-
ATM is required for efficient recombination between immunoglobulin switch regions
-
Reina-San-Martin, B., H.T. Chen, A. Nussenzweig, and M.C. Nussenzweig. 2004. ATM is required for efficient recombination between immunoglobulin switch regions. J. Exp. Med. 200:1103-1110.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 1103-1110
-
-
Reina-San-Martin, B.1
Chen, H.T.2
Nussenzweig, A.3
Nussenzweig, M.C.4
-
16
-
-
0037377943
-
ATM is not required in somatic hypermutation of VH, but is involved in the introduction of mutations in the switch mu region
-
Pan-Hammarstrom, Q., S. Dai, Y. Zhao, I.F. van Dijk-Hard, R.A. Gatti, A.L. Borresen-Dale, and L. Hammarstrom. 2003. ATM is not required in somatic hypermutation of VH, but is involved in the introduction of mutations in the switch mu region. J. Immunol. 170:3707-3716.
-
(2003)
J. Immunol.
, vol.170
, pp. 3707-3716
-
-
Pan-Hammarstrom, Q.1
Dai, S.2
Zhao, Y.3
Van Dijk-Hard, I.F.4
Gatti, R.A.5
Borresen-Dale, A.L.6
Hammarstrom, L.7
-
17
-
-
12744259733
-
Activation-induced deaminase: Controversies and open questions
-
Barreto, V.M., A.R. Ramiro, and M.C. Nussenzweig. 2005. Activation-induced deaminase: controversies and open questions. Trends Immunol. 26:90-96.
-
(2005)
Trends Immunol.
, vol.26
, pp. 90-96
-
-
Barreto, V.M.1
Ramiro, A.R.2
Nussenzweig, M.C.3
-
18
-
-
11844269804
-
Evolution of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases
-
Conticello, S.G., C.J. Thomas, S.K. Petersen-Mahrt, and M.S. Neuberger. 2005. Evolution of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases. Mol. Biol. Evol. 22:367-377.
-
(2005)
Mol. Biol. Evol.
, vol.22
, pp. 367-377
-
-
Conticello, S.G.1
Thomas, C.J.2
Petersen-Mahrt, S.K.3
Neuberger, M.S.4
-
19
-
-
0038293484
-
Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand
-
Ramiro, A.R., P. Stavropoulos, M. Jankovic, and M.C. Nussenzweig. 2003. Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand. Nat. Immunol. 4:452-456.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 452-456
-
-
Ramiro, A.R.1
Stavropoulos, P.2
Jankovic, M.3
Nussenzweig, M.C.4
-
20
-
-
1642406222
-
Recombinogenic phenotype of human activation-induced cytosine deaminase
-
Poltoratsky, V.P., S.H. Wilson, T.A. Kunkel, and Y.I. Pavlov. 2004. Recombinogenic phenotype of human activation-induced cytosine deaminase. J. Immunol. 172:4308-4313.
-
(2004)
J. Immunol.
, vol.172
, pp. 4308-4313
-
-
Poltoratsky, V.P.1
Wilson, S.H.2
Kunkel, T.A.3
Pavlov, Y.I.4
-
21
-
-
0037026482
-
Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase
-
Di Noia, J., and M.S. Neuberger. 2002. Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase. Nature. 419:43-48.
-
(2002)
Nature
, vol.419
, pp. 43-48
-
-
Di Noia, J.1
Neuberger, M.S.2
-
22
-
-
4344654828
-
Identification of the activation-induced cytidine deaminase gene from zebrafish: An evolutionary analysis
-
Zhao, Y., Q. Pan-Hammarstrom, Z. Zhao, and L. Hammarstrom. 2005. Identification of the activation-induced cytidine deaminase gene from zebrafish: an evolutionary analysis. Dev. Comp. Immunol. 29:61-71.
-
(2005)
Dev. Comp. Immunol.
, vol.29
, pp. 61-71
-
-
Zhao, Y.1
Pan-Hammarstrom, Q.2
Zhao, Z.3
Hammarstrom, L.4
-
23
-
-
0027190015
-
DNA sequences at immunoglobulin switch region recombination sites
-
Dunnick, W., G.Z. Hertz, L. Scappino, and C. Gritzmacher. 1993. DNA sequences at immunoglobulin switch region recombination sites. Nucleic Acids Res. 21:365-372.
-
(1993)
Nucleic Acids Res.
, vol.21
, pp. 365-372
-
-
Dunnick, W.1
Hertz, G.Z.2
Scappino, L.3
Gritzmacher, C.4
-
24
-
-
3142765336
-
Class-switch recombination: Interplay of transcription, DNA deamination and DNA repair
-
Chaudhuri, J., and F.W. Alt. 2004. Class-switch recombination: interplay of transcription, DNA deamination and DNA repair. Nat. Rev. Immunol. 4:541-552.
-
(2004)
Nat. Rev. Immunol.
, vol.4
, pp. 541-552
-
-
Chaudhuri, J.1
Alt, F.W.2
-
25
-
-
0023187644
-
Mitogen-driven B cell proliferation and differentiation are not accompanied by hypermutation of immunoglobulin variable region genes
-
Manser, T. 1987. Mitogen-driven B cell proliferation and differentiation are not accompanied by hypermutation of immunoglobulin variable region genes. J. Immunol. 139:234-238.
-
(1987)
J. Immunol.
, vol.139
, pp. 234-238
-
-
Manser, T.1
-
26
-
-
0041381361
-
AID mutant analyses indicate requirement for class-switch-specific cofactors
-
Ta, V.T., H. Nagaoka, N. Catalan, A. Durandy, A. Fischer, K. Imai, S. Nonoyama, J. Tashiro, M. Ikegawa, S. Ito, et al. 2003. AID mutant analyses indicate requirement for class-switch-specific cofactors. Nat. Immunol. 4:843-848.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 843-848
-
-
Ta, V.T.1
Nagaoka, H.2
Catalan, N.3
Durandy, A.4
Fischer, A.5
Imai, K.6
Nonoyama, S.7
Tashiro, J.8
Ikegawa, M.9
Ito, S.10
-
27
-
-
0141992113
-
C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion
-
Barreto, V., B. Reina-San-Martin, A.R. Ramiro, K.M. McBride, and M.C. Nussenzweig. 2003. C-terminal deletion of AID uncouples class switch recombination from somatic hypermutation and gene conversion. Mol. Cell. 12:501-508.
-
(2003)
Mol. Cell
, vol.12
, pp. 501-508
-
-
Barreto, V.1
Reina-San-Martin, B.2
Ramiro, A.R.3
McBride, K.M.4
Nussenzweig, M.C.5
-
28
-
-
1642370059
-
Non-redundancy of cytidine deaminases in class switch recombination
-
Fugmann, S.D., J.S. Rush, and D.G. Schatz. 2004. Non-redundancy of cytidine deaminases in class switch recombination. Eur. J. Immunol. 34:844-849.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 844-849
-
-
Fugmann, S.D.1
Rush, J.S.2
Schatz, D.G.3
-
29
-
-
0041931059
-
The E box motif CAGGTG enhances somatic hypermutation without enhancing transcription
-
Michael, N., H.M. Shen, S. Longerich, N. Kim, A. Longacre, and U. Storb. 2003. The E box motif CAGGTG enhances somatic hypermutation without enhancing transcription. Immunity. 19:235-242.
-
(2003)
Immunity
, vol.19
, pp. 235-242
-
-
Michael, N.1
Shen, H.M.2
Longerich, S.3
Kim, N.4
Longacre, A.5
Storb, U.6
-
30
-
-
1642334586
-
Cloning and expression of the AID gene in the channel catfish
-
Saunders, H.L., and B.G. Magor. 2004. Cloning and expression of the AID gene in the channel catfish. Dev. Comp. Immunol. 28:657-663.
-
(2004)
Dev. Comp. Immunol.
, vol.28
, pp. 657-663
-
-
Saunders, H.L.1
Magor, B.G.2
|