메뉴 건너뛰기




Volumn 8, Issue 1, 2012, Pages 149-160

Synthesis and characterization of chitosan/chondroitin sulfate/nano- SiO 2 composite scaffold for bone tissue engineering

Author keywords

Biomaterials; Bone regeneration; Chitosan; Chondroitin sulfate; Tissue engineering

Indexed keywords

BONE REGENERATION; BONE TISSUE ENGINEERING; CELL ATTACHMENTS; CELL SEEDING; CHONDROITIN SULFATES; COMPOSITE SCAFFOLDS; GLYCOSAMINOGLYCANS; IN-VITRO; MECHANICAL INTEGRITY; NANO- SIO; OSTEOCONDUCTIVE; PROTEIN ADSORPTION;

EID: 84861476530     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2012.1363     Document Type: Article
Times cited : (80)

References (59)
  • 1
    • 0005356151 scopus 로고
    • Tissue engineering
    • R. Langer and J. P. Vacanti, Tissue engineering. Science 920, 260 (1993).
    • (1993) Science , vol.920 , pp. 260
    • Langer, R.1    Vacanti, J.P.2
  • 3
    • 0037333116 scopus 로고    scopus 로고
    • Structure and properties of bilayer chitosan-gelatin scaffolds
    • J. S. Mao, L. G. Zhao, Y. J. Yin, and K. D. Yao, Structure and properties of bilayer chitosan-gelatin scaffolds. Biomaterials 24, 1067 (2003).
    • (2003) Biomaterials , vol.24 , pp. 1067
    • Mao, J.S.1    Zhao, L.G.2    Yin, Y.J.3    Yao, K.D.4
  • 5
    • 59249098389 scopus 로고    scopus 로고
    • Chitins and chitosan for the repair of wounded skin, nerve, cartilage and bone
    • R. A. A. Muzzarelli, Chitins and chitosan for the repair of wounded skin, nerve, cartilage and bone. Carbohydr. Polym. 76, 167 (2009).
    • (2009) Carbohydr. Polym. , vol.76 , pp. 167
    • Muzzarelli, R.A.A.1
  • 6
    • 78650519154 scopus 로고    scopus 로고
    • Chitosan composites with inorganics, morphogenetic proteins and stem cells for bone regeneration
    • R. A. A. Muzzarelli, Chitosan composites with inorganics, morphogenetic proteins and stem cells for bone regeneration. Carbohydr. Polym. 83, 1433 (2011).
    • (2011) Carbohydr. Polym. , vol.83 , pp. 1433
    • Muzzarelli, R.A.A.1
  • 7
    • 77955412875 scopus 로고    scopus 로고
    • Biomedical applications of chitin and chitosan based nano materials-A short review
    • R. Jayakumar, D. Menon, K. Manzoor, S. V. Nair, and H. Tamura, Biomedical applications of chitin and chitosan based nano materials-A short review. Carbohydr. Polym. 82, 227 (2010).
    • (2010) Carbohydr. Polym. , vol.82 , pp. 227
    • Jayakumar, R.1    Menon, D.2    Manzoor, K.3    Nair, S.V.4    Tamura, H.5
  • 8
    • 80052338818 scopus 로고    scopus 로고
    • Chitosan coated furosemide liposomes for improved bioavailability
    • I. Vural, C. Sarisozen, and S. S. Olmez, Chitosan coated furosemide liposomes for improved bioavailability. J. Biomed. Nanotechnol. 7, 426 (2011).
    • (2011) J. Biomed. Nanotechnol. , vol.7 , pp. 426
    • Vural, I.1    Sarisozen, C.2    Olmez, S.S.3
  • 9
    • 79960983018 scopus 로고    scopus 로고
    • Fabrication of porous chitosan/poly(vinyl alcohol) reinforced single-walled carbon nanotube nanocomposites for neural tissue engineering
    • M. A. Shokrgozar, F. Mottaghitalab, V. Mottaghitalab, and M. Farokhi, Fabrication of porous chitosan/poly(vinyl alcohol) reinforced single-walled carbon nanotube nanocomposites for neural tissue engineering. J. Biomed. Nanotechnol. 7, 276 (2011).
    • (2011) J. Biomed. Nanotechnol. , vol.7 , pp. 276
    • Shokrgozar, M.A.1    Mottaghitalab, F.2    Mottaghitalab, V.3    Farokhi, M.4
  • 10
    • 80052313903 scopus 로고    scopus 로고
    • No enhanced expression and infectivity of porcine endogenous retrovirus in primary porcine hepatocytes with chitosan nanofiber scaffold
    • B. Han, X. Shi, Z.-Z. Gu, J. Xiao, X. Chu, J. Gu, Y. Zhang, J. Tan, and Y. Ding, No enhanced expression and infectivity of porcine endogenous retrovirus in primary porcine hepatocytes with chitosan nanofiber scaffold. J. Biomed. Nanotechnol. 7, 377 (2011).
    • (2011) J. Biomed. Nanotechnol. , vol.7 , pp. 377
    • Han, B.1    Shi, X.2    Gu, Z.-Z.3    Xiao, J.4    Chu, X.5    Gu, J.6    Zhang, Y.7    Tan, J.8    Ding, Y.9
  • 11
    • 77955447560 scopus 로고    scopus 로고
    • Biocompatibility of nanostructured chitosan/poly(vinyl alcohol) blends chemically crosslinked with genipin for biomedical applications
    • V. M. Bispo, A. A. P. Mansur, E. F. B. Stancioli, and H. S. Mansur, Biocompatibility of nanostructured chitosan/poly(vinyl alcohol) blends chemically crosslinked with genipin for biomedical applications. J. Biomed. Nanotechnol. 6, 166 (2010).
    • (2010) J. Biomed. Nanotechnol. , vol.6 , pp. 166
    • Bispo, V.M.1    Mansur, A.A.P.2    Stancioli, E.F.B.3    Mansur, H.S.4
  • 12
    • 79953016653 scopus 로고    scopus 로고
    • Chitosan coated PLA nanoparticles for ophthalmic delivery: Characterization, in-vitro and in-vivo study in rabbit eye
    • R. C. Nagarwal, P. N. Singh, S. Kant, P. Maiti, and J. K. Pandit, Chitosan coated PLA nanoparticles for ophthalmic delivery: Characterization, in-vitro and in-vivo study in rabbit eye. J. Biomed. Nanotechnol. 6, 648 (2010).
    • (2010) J. Biomed. Nanotechnol. , vol.6 , pp. 648
    • Nagarwal, R.C.1    Singh, P.N.2    Kant, S.3    Maiti, P.4    Pandit, J.K.5
  • 14
    • 79953015192 scopus 로고    scopus 로고
    • High entrapment efficiency of chitosan/polylactic acid/tripolyphotspate nanosized microcapsules for rapamycin by an emulsion-evaporation approach
    • J. Fu, D. Wang, T. Wang, W. Yang, Y. Deng, H. Wang, S. Jin, and N. He, High entrapment efficiency of chitosan/polylactic acid/tripolyphotspate nanosized microcapsules for rapamycin by an emulsion-evaporation approach. J. Biomed. Nanotechnol. 6, 725 (2010).
    • (2010) J. Biomed. Nanotechnol. , vol.6 , pp. 725
    • Fu, J.1    Wang, D.2    Wang, T.3    Yang, W.4    Deng, Y.5    Wang, H.6    Jin, S.7    He, N.8
  • 15
    • 76749159914 scopus 로고    scopus 로고
    • Chitosan/sodium tripolyphosphate nanoparticles: Preparation, characterization and application as drug carrier
    • W. Yang, J. Fu, T. Wang, and N. He, Chitosan/sodium tripolyphosphate nanoparticles: Preparation, characterization and application as drug carrier. J. Biomed. Nanotechnol. 5, 591 (2009).
    • (2009) J. Biomed. Nanotechnol. , vol.5 , pp. 591
    • Yang, W.1    Fu, J.2    Wang, T.3    He, N.4
  • 16
    • 77949655144 scopus 로고    scopus 로고
    • Preparation and characterization of chitosan-gelatin/nano hydroxyapatite composite scaffolds for tissue engineering applications
    • M. Peter, G. Nitya, N. Selvamurugan, S. V. Nair, T. Furuike, H. Tamura, and R. Jayakumar, Preparation and characterization of chitosan-gelatin/nano hydroxyapatite composite scaffolds for tissue engineering applications. Carbohydr. Polym. 80, 687 (2010).
    • (2010) Carbohydr. Polym. , vol.80 , pp. 687
    • Peter, M.1    Nitya, G.2    Selvamurugan, N.3    Nair, S.V.4    Furuike, T.5    Tamura, H.6    Jayakumar, R.7
  • 17
    • 55049102728 scopus 로고    scopus 로고
    • Fabrication and characterization of chondroitin sulfatemodified chitosan membranes for biomedical applications
    • N. Y. Yuan, R. Y. Tsai, M. H. Ho, D. M. Wang, J. Y. Lai, and H. J. Hsieh, Fabrication and characterization of chondroitin sulfatemodified chitosan membranes for biomedical applications. Desalination 234, 166 (2008).
    • (2008) Desalination , vol.234 , pp. 166
    • Yuan, N.Y.1    Tsai, R.Y.2    Ho, M.H.3    Wang, D.M.4    Lai, J.Y.5    Hsieh, H.J.6
  • 18
    • 79952201212 scopus 로고    scopus 로고
    • Effects of chitosancarboxymethyl dextran nanoparticles on cell proliferation and on serum cytokine regulation
    • Y.-S. Lin, Y. Okamoto, and S. Minami, Effects of chitosancarboxymethyl dextran nanoparticles on cell proliferation and on serum cytokine regulation. J. Biomed. Nanotechnol. 6, 247 (2010).
    • (2010) J. Biomed. Nanotechnol. , vol.6 , pp. 247
    • Lin, Y.-S.1    Okamoto, Y.2    Minami, S.3
  • 19
    • 79952200343 scopus 로고    scopus 로고
    • Study on chitosan/polycaprolactone blending vascular scaffolds by electrospinning
    • W. Yang, J. Fu, D. Wang, T. Wang, H. Wang, S. Jin, and N. He, Study on chitosan/polycaprolactone blending vascular scaffolds by electrospinning. J. Biomed. Nanotechnol. 6, 254 (2010).
    • (2010) J. Biomed. Nanotechnol. , vol.6 , pp. 254
    • Yang, W.1    Fu, J.2    Wang, D.3    Wang, T.4    Wang, H.5    Jin, S.6    He, N.7
  • 20
    • 0033964687 scopus 로고    scopus 로고
    • Development of tailor-made collagen-glycosaminoglycan matrices: EDC/NHS crosslinking, and ultrastructural aspects
    • J. S. Pieper, T. Hafmans, J. H. Veerkamp, and T. H. Kuppevelt, Development of tailor-made collagen-glycosaminoglycan matrices: EDC/NHS crosslinking, and ultrastructural aspects. Biomaterials 21, 581 (2000).
    • (2000) Biomaterials , vol.21 , pp. 581
    • Pieper, J.S.1    Hafmans, T.2    Veerkamp, J.H.3    Kuppevelt, T.H.4
  • 21
    • 76749136294 scopus 로고    scopus 로고
    • Characterization of a new scaffold formed of polyelectrolyte complexes using atomic force and ultrasonic force microscopy
    • O. Valdés, and M. T. Cuberes, Characterization of a new scaffold formed of polyelectrolyte complexes using atomic force and ultrasonic force microscopy. J. Biomed. Nanotechnol. 5, 716 (2009).
    • (2009) J. Biomed. Nanotechnol. , vol.5 , pp. 716
    • Valdés, O.1    Cuberes, M.T.2
  • 23
    • 58149178619 scopus 로고    scopus 로고
    • Mineralization of biomimetically carboxymethylated collagen fibrils in a model dual membrane diffusion system
    • H. Ehrlich, T. Hanke, C. Fischer, U. Schwarzenbolz, T. Henle, R. Born, and H. Worch, Mineralization of biomimetically carboxymethylated collagen fibrils in a model dual membrane diffusion system. J. Membr. Sci. 326, 254 (2008).
    • (2008) J. Membr. Sci. , vol.326 , pp. 254
    • Ehrlich, H.1    Hanke, T.2    Fischer, C.3    Schwarzenbolz, U.4    Henle, T.5    Born, R.6    Worch, H.7
  • 25
    • 0014951015 scopus 로고
    • Silicon: A possible factor in bone calcification
    • E. M. Carlisle, Silicon: A possible factor in bone calcification. Science 167, 279 (1970).
    • (1970) Science , vol.167 , pp. 279
    • Carlisle, E.M.1
  • 26
    • 0015496222 scopus 로고
    • Growth-promoting effects of silicon in rats
    • K. Schwarz and D. B. Milne, Growth-promoting effects of silicon in rats. Nature 239, 333 (1972).
    • (1972) Nature , vol.239 , pp. 333
    • Schwarz, K.1    Milne, D.B.2
  • 28
    • 84861477547 scopus 로고    scopus 로고
    • Silica based nanoparticles and methods of stimulating bone formation and suppressing bone resorption through modulation of NF-KB
    • U.S Patent 20100297246 November
    • M. N. Weitzmann, G. R. Beck, and J. Lee, Silica based nanoparticles and methods of stimulating bone formation and suppressing bone resorption through modulation of NF-KB. U.S Patent 20100297246 November (2010).
    • (2010)
    • Weitzmann, M.N.1    Beck, G.R.2    Lee, J.3
  • 29
    • 33846144142 scopus 로고    scopus 로고
    • Extracellular matrix formation and mineralization on a phosphate-free porous bioactive glass scaffold using primary human osteoblast (HOB) cells
    • J. R. Jones, O. Tsigkou, E. E. Coates, M. M. Stevens, J. M. Polak, and J. M. L. L. Hench, Extracellular matrix formation and mineralization on a phosphate-free porous bioactive glass scaffold using primary human osteoblast (HOB) cells. Biomaterials 28, 1653 (2007).
    • (2007) Biomaterials , vol.28 , pp. 1653
    • Jones, J.R.1    Tsigkou, O.2    Coates, E.E.3    Stevens, M.M.4    Polak, J.M.5    Hench, J.M.L.L.6
  • 31
    • 48449098779 scopus 로고    scopus 로고
    • Preparation and in vitro characterization of scaffolds of poly (L-lactic acid) containing bioactive glass ceramic nanoparticles
    • Z. Hong, R. L. Reis, and J. F. Mano, Preparation and in vitro characterization of scaffolds of poly (L-lactic acid) containing bioactive glass ceramic nanoparticles. Acta Biomater. 4, 1297 (2008).
    • (2008) Acta Biomater. , vol.4 , pp. 1297
    • Hong, Z.1    Reis, R.L.2    Mano, J.F.3
  • 33
    • 80052880249 scopus 로고    scopus 로고
    • The effects of replacing collagen fibers with carbon nanotubes on the rate of bone remodeling process
    • N. Jamilpour, A. Fereidoon, and G. Rouhi, The effects of replacing collagen fibers with carbon nanotubes on the rate of bone remodeling process. J. Biomed. Nanotechnol. 7, 542 (2011).
    • (2011) J. Biomed. Nanotechnol. , vol.7 , pp. 542
    • Jamilpour, N.1    Fereidoon, A.2    Rouhi, G.3
  • 34
    • 80052882696 scopus 로고    scopus 로고
    • Preparation and characterization of nano-hydroxyapatite/poly(vinyl alcohol) composite membranes for guided bone regeneration
    • S. Zeng, S. Fu, G. Guo, H. Liang, Z. Qian, X. Tang, and F. Luo, Preparation and characterization of nano-hydroxyapatite/poly(vinyl alcohol) composite membranes for guided bone regeneration. J. Biomed. Nanotechnol. 7, 549 (2011).
    • (2011) J. Biomed. Nanotechnol. , vol.7 , pp. 549
    • Zeng, S.1    Fu, S.2    Guo, G.3    Liang, H.4    Qian, Z.5    Tang, X.6    Luo, F.7
  • 38
    • 69249196803 scopus 로고    scopus 로고
    • Acute and subacute toxicity studies of chitosan reduced gold nanoparticles: A novel carrier for therapeutic agents
    • V. Pokharkar, S. Dhar, D. Bhumkar, V. Mali, S. Bodhankar, and B. L. V. Prasad, Acute and subacute toxicity studies of chitosan reduced gold nanoparticles: A novel carrier for therapeutic agents. J. Biomed. Nanotechnol. 5, 233 (2009).
    • (2009) J. Biomed. Nanotechnol. , vol.5 , pp. 233
    • Pokharkar, V.1    Dhar, S.2    Bhumkar, D.3    Mali, V.4    Bodhankar, S.5    Prasad, B.L.V.6
  • 39
    • 67649366349 scopus 로고    scopus 로고
    • Ionically crosslinked chitosan nanoparticles as gene delivery systems: Effect of PEGylation degree on in vitro and in vivo gene transfer
    • N. Csaba, M. K.-Höggård, E. F.-Megia, R. N.-Carballal, R. Riguera, and M. J. Alonso, Ionically crosslinked chitosan nanoparticles as gene delivery systems: Effect of PEGylation degree on in vitro and in vivo gene transfer. J. Biomed. Nanotechnol. 5, 162 (2009).
    • (2009) J. Biomed. Nanotechnol. , vol.5 , pp. 162
    • Csaba, N.1    K-Höggård, M.2    F-Megia, E.3    N-Carballal, R.4    Riguera, R.5    Alonso, M.J.6
  • 42
    • 77952108714 scopus 로고    scopus 로고
    • Chitin and collagen as universal and alternative templates in biomineralization
    • H. Ehrlich, Chitin and collagen as universal and alternative templates in biomineralization. Int. Geol. Rev. 52, 661 (2010).
    • (2010) Int. Geol. Rev. , vol.52 , pp. 661
    • Ehrlich, H.1
  • 44
    • 79955508072 scopus 로고    scopus 로고
    • Collagen, a huge matrix in glass-sponge flexible spicules of the meter-long hyalonema sieboldi
    • edited by Bäuerlein, Wiley VCH, Weinheim, Chap. 2
    • H. Ehrlich and H. Worch, Collagen, a huge matrix in glass-sponge flexible spicules of the meter-long hyalonema sieboldi, Handbook of Biomineralization, The Biology of Biominerals Structure Formation, edited by Bäuerlein, Wiley VCH, Weinheim, (2007), Vol. 1. Chap. 2. pp. 23-41.
    • (2007) Handbook of Biomineralization, the Biology of Biominerals Structure Formation , vol.1 , pp. 23-41
    • Ehrlich, H.1    Worch, H.2
  • 45
    • 76749093193 scopus 로고    scopus 로고
    • A novel methotrexate delivery system based on chitosan-methotrexate covalently conjugated nanoparticles
    • P. Wu, X. He, K. Wang, W. Tan, C. He, and M. Zheng, A novel methotrexate delivery system based on chitosan-methotrexate covalently conjugated nanoparticles. J. Biomed. Nanotechnol. 5, 557 (2009).
    • (2009) J. Biomed. Nanotechnol. , vol.5 , pp. 557
    • Wu, P.1    He, X.2    Wang, K.3    Tan, W.4    He, C.5    Zheng, M.6
  • 46
    • 56349138058 scopus 로고    scopus 로고
    • Preparation of chitosan-gelatin hybrid scaffolds with well-organized microstructures for hepatic tissue engineering
    • H. Jiankang, L. Dichen, L. Yaxiong, Y. Bo, Z. Hanxiang, L. Qin, L. Bingheng, and L. Yi, Preparation of chitosan-gelatin hybrid scaffolds with well-organized microstructures for hepatic tissue engineering. Acta Biomater. 5, 453 (2009).
    • (2009) Acta Biomater. , vol.5 , pp. 453
    • Jiankang, H.1    Dichen, L.2    Yaxiong, L.3    Bo, Y.4    Hanxiang, Z.5    Qin, L.6    Bingheng, L.7    Yi, L.8
  • 47
    • 34347325024 scopus 로고    scopus 로고
    • Fabrication and characterization of chitosan/gelatin porous scaffolds with predefined internal microstructures
    • H. Jiankang, L. Dichen, L. Yaxiong, Y. Bo, L. Bingheng, and L. Qin, Fabrication and characterization of chitosan/gelatin porous scaffolds with predefined internal microstructures. Polymer 48, 4578 (2007).
    • (2007) Polymer , vol.48 , pp. 4578
    • Jiankang, H.1    Dichen, L.2    Yaxiong, L.3    Bo, Y.4    Bingheng, L.5    Qin, L.6
  • 48
    • 32144437418 scopus 로고    scopus 로고
    • How useful is SBF in predicting in vivo bone bioactivity?
    • T. Kokubo and H. Takadama, How useful is SBF in predicting in vivo bone bioactivity? Biomaterials 27, 2907 (2006).
    • (2006) Biomaterials , vol.27 , pp. 2907
    • Kokubo, T.1    Takadama, H.2
  • 49
  • 50
    • 33947182228 scopus 로고    scopus 로고
    • Biopolymer composite of chitosan and methyl methacrylate for medical applications
    • C. Radhakumary, P. D. Nair, S. Mathew, and C. P. R. Nair, Biopolymer composite of chitosan and methyl methacrylate for medical applications. Trends Biomater. Artif. Organs 18, 117 (2005).
    • (2005) Trends Biomater. Artif. Organs , vol.18 , pp. 117
    • Radhakumary, C.1    Nair, P.D.2    Mathew, S.3    Nair, C.P.R.4
  • 51
    • 59349120485 scopus 로고    scopus 로고
    • The effects of collagen concentration and crosslink density on the biological, structural and mechanical properties of collagen- GAG scaffolds for bone tissue engineering
    • C. M. Tierney, M. G. Haugh, J. Liedl, F. Mulcahy, B. Hayes, and F. J. O'Brien, The effects of collagen concentration and crosslink density on the biological, structural and mechanical properties of collagen- GAG scaffolds for bone tissue engineering. J. Mech. Behav. Biomed. Mater. 2, 202 (2009).
    • (2009) J. Mech. Behav. Biomed. Mater. , vol.2 , pp. 202
    • Tierney, C.M.1    Haugh, M.G.2    Liedl, J.3    Mulcahy, F.4    Hayes, B.5    O'Brien, F.J.6
  • 52
    • 33947409096 scopus 로고    scopus 로고
    • Fabrication of porous hyroxyapatite-gelatin composite scaffolds for bone tissue engineering
    • M. K. Narbat, F. Orang, M. S. Hashtjin, and A. Goudarzi, Fabrication of porous hyroxyapatite-gelatin composite scaffolds for bone tissue engineering. Iran. Biomed. J. 10, 215 (2006).
    • (2006) Iran. Biomed. J. , vol.10 , pp. 215
    • Narbat, M.K.1    Orang, F.2    Hashtjin, M.S.3    Goudarzi, A.4
  • 53
    • 68749115164 scopus 로고    scopus 로고
    • Natural stimulus responsive scaffolds/cells for bone tissue engineering: Influence of lysozyme upon scaffold degradation and osteogenic differentiation of cultured marrow stromal cells induced by CaP coatings
    • A. M. Martins, Q. P. Pham, P. B. Malafaya, R. M. Raphael, F. K. Kasper, R. L. Reis, and A. G. Mikos, Natural stimulus responsive scaffolds/cells for bone tissue engineering: Influence of lysozyme upon scaffold degradation and osteogenic differentiation of cultured marrow stromal cells induced by CaP coatings. Tissue Eng. A. 15, 1953 (2009).
    • (2009) Tissue Eng. A. , vol.15 , pp. 1953
    • Martins, A.M.1    Pham, Q.P.2    Malafaya, P.B.3    Raphael, R.M.4    Kasper, F.K.5    Reis, R.L.6    Mikos, A.G.7
  • 54
    • 33644794744 scopus 로고    scopus 로고
    • Mineralization of chitosan scaffolds with nano-apatite formation by double diffusion technique
    • I. Manjubala, S. Scheler, J. Bossert, and K. D. Jandt, Mineralization of chitosan scaffolds with nano-apatite formation by double diffusion technique. Acta Biomater. 2, 75 (2006).
    • (2006) Acta Biomater. , vol.2 , pp. 75
    • Manjubala, I.1    Scheler, S.2    Bossert, J.3    Jandt, K.D.4
  • 57
    • 79953007389 scopus 로고    scopus 로고
    • Carbon nanotubes as a scaffold for spermatogonial cell maintenance
    • T. Rafeeqi, and G. Kaul, Carbon nanotubes as a scaffold for spermatogonial cell maintenance. J. Biomed. Nanotechnol. 6, 710 (2010).
    • (2010) J. Biomed. Nanotechnol. , vol.6 , pp. 710
    • Rafeeqi, T.1    Kaul, G.2
  • 58
    • 72949086588 scopus 로고    scopus 로고
    • Surface phosphorylation of chitosan significantly improves osteoblast cell viability, attachment and proliferation
    • P. M. L. Perez, R. M. P. Da-Silva, C. Serra, I. Pashkuleva, and R. L. Reis, Surface phosphorylation of chitosan significantly improves osteoblast cell viability, attachment and proliferation. J. Mater. Chem. 20, 483 (2010).
    • (2010) J. Mater. Chem. , vol.20 , pp. 483
    • Perez, P.M.L.1    Da-Silva, R.M.P.2    Serra, C.3    Pashkuleva, I.4    Reis, R.L.5
  • 59
    • 67749140074 scopus 로고    scopus 로고
    • Non-linear elasticity of extra cellular matrices enables contractile cells to communicate local position and orientation
    • P. A.
    • J. P. Winer, S. Oake, and P. A. Janmey, P. A. Non-linear elasticity of extra cellular matrices enables contractile cells to communicate local position and orientation. Plos One 4, e6382 (2009).
    • (2009) Plos One , vol.4
    • Winer, J.P.1    Oake, S.2    Janmey, P.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.