Natural stimulus responsive scaffolds/cells for bone tissue engineering: Influence of lysozyme upon scaffold degradation and osteogenic differentiation of cultured marrow stromal cells induced by CaP coatings

Tissue Engineering - Part A

Volumn 15, Issue 8, 2009, Pages 1953-1963

  Martins, Ana M ^a,b   Pham, Quynh P ^b   Malafaya, Patrícia B ^a   Raphael, Robert M ^b   Kasper, F Kurtis ^b   Reis, Rui L ^a   Mikos, Antonios G ^b  

^a UNIVERSITY OF MINHO   (Portugal)

^b Rice University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMIMETIC MATERIALS; BIOMIMETICS; BONE; CALCIUM; CALCIUM ALLOYS; CALCIUM PHOSPHATE; CELL CULTURE; CHITIN; CHITOSAN; DEGRADATION; ENZYMES; FLOWCHARTING; INTERCONNECTION NETWORKS; PHOSPHATE COATINGS; TISSUE ENGINEERING;

BIODEGRADABLE SCAFFOLD; BIOMIMETIC COATING; BONE MATRIX; BONE REGENERATION; BONE TISSUE ENGINEERING; CALCIUM DEPOSITION; DEGRADATION PROFILES; DEGRADATION STUDY; DEGRADATION TEST; IMMERSION TIME; IN-SITU; INTERCONNECTED PORE NETWORKS; INTERCONNECTED PORES; MARROW STROMAL CELL; MATRIX; OSTEOGENIC DIFFERENTIATION; OVERALL VISION; PORE FORMATION; POSITIVE EFFECTS; SCAFFOLD DEGRADATION; THREE-DIMENSIONAL STRUCTURE;

SCAFFOLDS;

BIOMIMETIC MATERIAL; CALCIUM PHOSPHATE; CHITOSAN; LYSOZYME; STARCH; TISSUE SCAFFOLD;

ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; BONE MARROW CELL; BONE MATRIX; BONE MINERALIZATION; BONE TISSUE; CELL DIFFERENTIATION; CHANNEL GATING; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DEGRADATION KINETICS; ENZYME DEGRADATION; INTERMETHOD COMPARISON; MALE; MATERIAL COATING; NONHUMAN; POROSITY; PRIORITY JOURNAL; RAT; STIMULUS RESPONSE; STROMA CELL; THREE DIMENSIONAL IMAGING; TISSUE ENGINEERING;

RATTUS;

ALKALINE PHOSPHATASE; ANIMALS; BIOLOGICAL ASSAY; BONE AND BONES; BONE MARROW CELLS; CALCIUM; CALCIUM PHOSPHATES; CELL DIFFERENTIATION; CELLS, CULTURED; CHITOSAN; COATED MATERIALS, BIOCOMPATIBLE; MALE; MESENCHYMAL STEM CELLS; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; MURAMIDASE; OSTEOGENESIS; POROSITY; RATS; RATS, WISTAR; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; STROMAL CELLS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 68749115164     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2008.0023     Document Type: Article

References (42)

1. Langer, R., and Vacanti, J.P. Tissue engineering. Science 260, 920, 1993.
2. Atala, A. Engineering tissues, organs and cells. J Tissue Eng Regen Med 1, 83, 2007.
3. Bruder, S.P., and Fox, B.S. Tissue engineering of bone. Cell based strategies. Clin Orthop Relat Res, S68, 1999.
4. Salgado, A.J., Coutinho, O.P., and Reis, R.L. Bone tissue engineering: state of the art and future trends. Macromol Biosci 4, 743, 2004.
5. Hutmacher, D.W., Schantz, J.T., Lam, C.X.F., Tarn, K.C., and Lim, T.C. State of the art and future directions of scaffold-based bone engineering from a biomaterials perspective. J Tissue Eng Regen Med 1, 245, 2007.
6. Martins, A.M., Santos, M.I., Azevedo, H.S., Malafaya, P.B., and Reis, R.L. Natural origin scaffolds with in situ pore forming capability for bone tissue engineering applications. Acta Biomater, 4, 1637, 2008.
7. Tuzlakoglu, K., Alves, C.M., Mano, J.F., and Reis, R.L. Production and characterization of chitosan fibers and 3-D fiber mesh scaffolds for tissue engineering applications. Macromol Biosci 4, 811, 2004.
8. Malafaya, P.B., Pedro, A.J., Peterbauer, A., Gabriel, C., Redl, H., and Reis, R.L. Chitosan particles agglomerated scaffolds for cartilage and osteochondral tissue engineering approaches with adipose tissue derived stem cells. J Mater Sci Mater Med 16, 1077, 2005.
9. Oliveira, J.M., Rodrigues, M.T., Silva, S.S., Malafaya, P.B., Gomes, M.E., Viegas, CA., Dias, I.R., Azevedo, J.T., Mano, J.F., and Reis, R.L. Novel hydroxyapatite/chitosan bilayered scaffold for osteochondral tissue-engineering applications: scaffold design and its performance when seeded with goat bone marrow stromal cells. Biomaterials 27, 6123, 2006.
10. Chatelet, C., Damour, O., and Domard, A. Influence of the degree of acetylation on some biological properties of chitosan films. Biomaterials 22, 261, 2001.
11. Klokkevold, P.R., Vandemark, L., Kenney, E.B., and Bernard, G.W. Osteogenesis enhanced by chitosan (poly-N-acetyl glucosaminoglycan) in vitro. J Periodontol 67, 1170, 1996.
12. Lahiji, A., Sohrabi, A., Hungerford, D.S., and Frondoza, CG. Chitosan supports the expression of extracellular matrix proteins in human osteoblasts and chondrocytes. J Biomed Mater Res 51, 586, 2000.
13. Pound, J.C., Green, D.W., Chaudhuri, J.B., Mann, S., Roach, H.I., and Oreffo, R.O. Strategies to promote chondrogenesis and osteogenesis from human bone marrow cells and articular chondrocytes encapsulated in polysaccharide templates. Tissue Eng 12, 2789, 2006.
14. Peluso, G., Petillo, O., Ranieri, M., Santin, M., Ambrosio, L., Calabro, D., Avallone, B., and Balsamo, G. Chitosan-mediated stimulation of macrophage function. Biomaterials 15, 1215, 1994.
15. Muzzarelli, R.A. Human enzymatic activities related to the therapeutic administration of chitin derivatives. Cell Mol Life Sci 53, 131, 1997.
16. Varum, K.M., Myhr, M.M., Hjerde, R.J., and Smidsrod, O. In vitro degradation rates of partially N-acetylated chitosans in human serum. Carbohydr Res 299, 99, 1997.
17. Tomihata, K., and Ikada, Y. In vitro and in vivo degradation of films of chitin and its deacetylated derivatives. Biomaterials 18, 567, 1997.
18. Mendes, S.C., Reis, R.L., Bovell, Y.P., Cunha, A.M., van Blitterswijk, CA., and de Bruijn, J.D. Biocompatibility testing of novel starch-based materials with potential application in orthopaedic surgery: a preliminary study. Biomaterials 22, 2057, 2001.
19. Marques, A.P., Reis, R.L., and Hunt, J.A. The biocompatibility of novel starch-based polymers and composites: in vitro studies. Biomaterials 23, 1471, 2002.
20. Salgado, A.J., Coutinho, O.P., Reis, R.L., and Davies, J.E. In vivo response to starch-based scaffolds designed for bone tissue engineering applications. J Biomed Mater Res A 80, 983, 2007.
21. Azevedo, H.S., Gama, F.M., and Reis, R.L. In vitro assessment of the enzymatic degradation of several starch based biomaterials. Biomacromolecules 4, 1703, 2003.
22. Azevedo, H.S., Leonor, I.B., Alves, C.M., and Reis, R.L. Incorporation of proteins and enzymes at different stages of the preparation of calcium phosphate coatings on a de-gradable substrate by a biomimetic methodology. Mater Sci Eng C-Bio S 25, 169, 2005.
23. Reis, R.L., and Cunha, A.M. Starch and starch based ther-mosplastic. In: Jurgen, K.H., Buschow, R., Cahn, W., Flemings, M.C., Ilschner, B., Kramer, E.J., and Mahajan, S., eds. Encyclopedia of Materials Science and Technology. Amsterdam: Pergamon-Elsevier Science, 2001, pp. 8810-8816.
24. Azevedo, H.S., and Reis, R.L. Understanding the enzymatic degradation of biodegradable polymers and strategies to control their degradation rate. In: Reis, R.L., and Roman, J.S., eds. Biodegradable Systems in Tissue Engineering and Regenerative Medicine, Boca Raton: CRC Press, pp. 177-201, 2005.
25. Liu, Y., Hunziker, E.B., Randall, N.X., de Groot, K., and Layrolle, P. Proteins incorporated into biomimetically prepared calcium phosphate coatings modulate their mechanical strength and dissolution rate. Biomaterials 24, 65, 2003.
26. Liu, Y., Hunziker, E.B., Layrolle, P., De Bruijn, J.D., and De Groot, K. Bone morphogenetic protein 2 incorporated into biomimetic coatings retains its biological activity. Tissue Eng 10, 101, 2004.
27. Azevedo, H.S., Leonor, I.B., and Reis, R.L. Incorporation of proteins with different isoelectric points into biomimetic Ca-P coatings: a new approach to produce hybrid coatings with tailored properties. Key Eng Mater 309, 755, 2006.
28. Ohtsuki, C., Kamitakahara, M., and Miyazaki, T. Coating bone-like apatite onto organic substrates using solutions mimicking body fluid. J Tissue Eng Regen Med 1, 33, 2007.
29. Barrere, F., van der Valk, C.M., Meijer, G., Dalmeijer, R.A., de Groot, K., and Layrolle, P. Osteointegration of biomimetic apatite coating applied onto dense and porous metal implants in femurs of goats. J Biomed Mater Res B Appl Bio-mater 67, 655, 2003.
30. Habobovic, P., and de Groot, K. Osteoinductive biomaterials - properties and relevance in bone repair. J Tissue Eng Regen Med 1, 25, 2007.
31. Abe, Y., Kokubo, T., and Yamamuro, T. Apatite coating on ceramics, metals and polymers utilizing a biological process. J Mater Sci Mater Med 1, 233, 1990.
32. Reis, R.L., Cunha, A.M., Fernandes, M.H., and Correia, R.N. Treatments to induce the nucleation and growth of apatite-like layers on polymeric surfaces and foams. J Mater Sci Mater Med 8, 897, 1997.
33. Martins, A.M., Salgado, A.J., Azevedo, H.S., Leonor, I.B., and Reis, R.L. Lysozyme incorporation in biomimetic coated chitosan scaffolds: development and behaviour in contact with osteoblastic-like cells. Tissue Eng 12, 1018, 2006.
34. Hacker, M., Ringhofer, M., Appel, B., Neubauer, M., Vogel, T., Young, S., Mikos, A.G., Blunk, T., Gopferich, A., and Schulz, M.B. Solid lipid templating of macroporous tissue engineering scaffolds. Biomaterials 28, 3497, 2007.
35. Lu, J.X., Flautre, B., Anselme, K., Hardouin, P., Gallur, A., Descamps, M., and Thierry, B. Role of interconnections in porous bioceramics on bone recolonization in vitro and in vivo. J Mater Sci Mater Med 10, 111, 1999.
36. Otsuki, B., Takemoto, M., Fujibayashi, S., Neo, M., Kokubo, T., and Nakamura, T. Pore throat size and connectivity determine bone and tissue ingrowth into porous implants: three-dimensional micro-CT based structural analyses of porous bioactive titanium implants. Biomaterials 27, 5892, 2006.
37. Shi, X., Sitharaman, B., Pham, Q.P., Liang, F., Wu, K., Edward Billups, W., Wilson, L.J., and Mikos, A.G. Fabrication of porous ultra-short single-walled carbon nanotube nano-composite scaffolds for bone tissue engineering. Biomaterials 28, 4078, 2007.
38. Maniatopoulos, C., Sodek, J., and Melcher, A.H. Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats. Cell Tissue Res 254, 317, 1988.
39. Datta, N., Holtorf, H.L., Sikavitsas, V.I., Jansen, J.A., and Mikos, A.G. Effect of bone extracellular matrix synthesized in vitro on the osteoblastic differentiation of marrow stromal cells. Biomaterials 26, 971, 2005.
40. Holtorf, H.L., Jansen, J.A., and Mikos, A.G. Ectopic bone formation in rat marrow stromal cell/titanium fiber mesh scaffold constructs: effect of initial cell phenotype. Biomaterials 26, 6208, 2005.
41. Toquet, J., Rohanizadeh, R., Guicheux, J., Couillaud, S., Passuti, N., Daculsi, G., and Heymann, D. Osteogenic potential in vitro of human bone marrow cells cultured on macroporous biphasic calcium phosphate ceramic. J Biomed Mater Res 44, 98, 1999.
42. Xie, J., Riley, C., Kumar, M., and Chittur, K. FTIR/ATR study of protein adsorption and brushite transformation to hydroxyapatite. Biomaterials 23, 3609, 2002.