The epitope and neutralization mechanism of AVFLuIgG01, a broad-reactive human monoclonal antibody against H5N1 influenza virus

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Cao, Zhiliang ^a   Meng, Jiazi ^a   Li, Xingxing ^a   Wu, Ruiping ^b   Huang, Yanxin ^c   He, Yuxian ^a  

^a INSTITUTE OF PATHOGEN BIOLOGY   (China)

^b WENZHOU MEDICAL UNIVERSITY   (China)

^c NORTHEAST NORMAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN F(AB) FRAGMENT; INFLUENZA VIRUS HEMAGGLUTININ; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY AVFLULGG01; UNCLASSIFIED DRUG;

AMINO ACID COMPOSITION; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; EPITOPE MAPPING; HUMAN; INFLUENZA A (H5N1); INFLUENZA VIRUS A H5N1; MEMBRANE FUSION; MOUSE; NONHUMAN; PH; PHARMACOLOGICAL BLOCKING; PROTEIN CONFORMATION; PROTEIN STRUCTURE; RECEPTOR BINDING; VIRUS ATTACHMENT; VIRUS INHIBITION; VIRUS NEUTRALIZATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; CELL LINE; COMPUTATIONAL BIOLOGY; EPITOPES; GIANT CELLS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; INFLUENZA A VIRUS, H5N1 SUBTYPE; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN CONFORMATION; VIRUS ATTACHMENT;

AVES; ORTHOMYXOVIRIDAE;

EID: 84861475076     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038126     Document Type: Article

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