Mapping antibody epitopes of the avian H5N1 influenza virus

PLoS Medicine

Volumn 6, Issue 4, 2009, Pages

  Yen, Hui Ling ^a   Peiris, J S Malik ^a,b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b HKU PASTEUR RESEARCH CENTRE   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; HEMAGGLUTININ; INFLUENZA VACCINE; MONOCLONAL ANTIBODY; SIALIDASE;

ANTIBODY RESPONSE; CROSS REACTION; GENE MAPPING; HUMAN; HUMORAL IMMUNE DEFICIENCY; HUMORAL IMMUNITY; INFECTION CONTROL; INFLUENZA; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H3N2; INFLUENZA VIRUS A H5N1; NONHUMAN; SHORT SURVEY; VIRUS NEUTRALIZATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, VIRAL; BIRDS; EPITOPES; GENOMIC LIBRARY; HEMAGGLUTININS; HUMANS; INFLUENZA A VIRUS, H5N1 SUBTYPE; INFLUENZA IN BIRDS; NEURAMINIDASE;

EID: 66149085695     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.1000064     Document Type: Short Survey

References (27)

1. Luke TC, Kilbane EM, Jackson JL, Hoffman SL (2006) Meta-analysis: Convalescent blood products for Spanish influenza pneumonia: A future H5N1 treatment? Ann Intern Med 145: 599-609.
2. Zhou B, Zhong N, Guan Y (2007) Treatment with convalescent plasma for influenza A (H5N1) infection. N Engl J Med 357: 1450-1451. (Pubitemid 47535608)
3. Simmons CP, Bernasconi NL, Suguitan Jr. AL, Mills K, Ward JM, et al. (2007) Prophylactic and therapeutic efficacy of human monoclonal antibodies against H5N1 influenza. PLoS Med 4: e178. doi:10.1371/journal.pmed.0040178. (Pubitemid 46842583)
4. Kashyap AK, Steel J, Oner AF, Dillon MA, Swale RE, et al. (2008) Combinatorial antibody libraries from survivors of the Turkish H5N1 avian influenza outbreak reveal virus neutralization strategies. Proc Natl Acad Sci U S A 105: 5986-5991.
5. Barbey-Martin C, Gigant B, Bizebard T, Calder LJ, Wharton SA, et al. (2002) An antibody that prevents the hemagglutinin low pH fusogenic transition. Virology 294: 70-74.
6. Yoden S, Kida H, Kuwabara M, Yanagawa R, Webster RG (1986) Spin-labeling of influenza virus hemagglutinin permits analysis of the conformational change at low pH and its inhibition by antibody. Virus Res 4: 251-261. (Pubitemid 16076731)
7. Knossow M, Gaudier M, Douglas A, Barrere B, Bizebard T, et al. (2002) Mechanism of neutralization of influenza virus infectivity by antibodies. Virology 302: 294-298. (Pubitemid 35373857)
8. Kida H, Webster RG, Yanagawa R (1983) Inhibition of virus-induced hemolysis with monoclonal antibodies to different antigenic areas on the hemagglutinin molecule of A/seal/Massachusetts/ 1/80 (H7N7) influenza virus. Arch Virol 76: 91-99.
9. Murphy BR, Kasel JA, Chanock RM (1972) Association of serum anti-neuraminidase antibody with resistance to influenza in man. N Engl J Med 286: 1329-1332.
10. Couch RB, Kasel JA, Gerin JL, Schulman JL, Kilbourne ED (1974) Induction of partial immunity to influenza by a neuraminidase-specific vaccine. J Infect Dis 129: 411-420.
11. Schulman JL, Khakpour M, Kilbourne ED (1968) Protective effects of specific immunity to viral neuraminidase on influenza virus infection of mice. J Virol 2: 778-786.
12. Webster RG, Reay PA, Laver WG (1988) Protection against lethal influenza with neuraminidase. Virology 164: 230-237. (Pubitemid 18132025)
13. Grebe KM, Yewdell JW, Bennink JR (2008) Heterosubtypic immunity to influenza A virus: Where do we stand? Microbes Infect 10: 1024-1029.
14. Bui HH, Peters B, Assarsson E, Mbawuike I, Sette A (2007) Ab and T cell epitopes of influenza A virus, knowledge and opportunities. Proc Natl Acad Sci U S A 104: 246-251. (Pubitemid 46068017)
15. Skehel JJ, Stevens DJ, Daniels RS, Douglas AR, KnossowM, et al. (1984) A carbohydrate side chain on hemagglutinins of Hong Kong influenza viruses inhibits recognition by a monoclonal antibody. Proc Natl Acad Sci U S A 81: 1779-1783. (Pubitemid 14149547)
16. Wiley DC, Wilson IA, Skehel JJ (1981) Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation. Nature 289: 373-378. (Pubitemid 11135143)
17. Caton AJ, Brownlee GG, Yewdell JW, GerhardW (1982) The antigenic structure of the influenza virus A/PR/8/34 hemagglutinin (H1 subtype). Cell 31: 417-427.
18. Tsuchiya E, Sugawara K, Hongo S, Matsuzaki Y, Muraki Y, et al. (2001) Antigenic structure of the haemagglutinin of human influenza A/H2N2 virus. J Gen Virol 82: 2475-2484. (Pubitemid 32936780)
19. Kaverin NV, Rudneva IA, Ilyushina NA, Varich NL, Lipatov AS, et al. (2002) Structure of antigenic sites on the haemagglutinin molecule of H5 avian influenza virus and phenotypic variation of escape mutants. J Gen Virol 83: 2497-2505.
20. Kaverin NV, Rudneva IA, Govorkova EA, Timofeeva TA, Shilov AA, et al. (2007) Epitope mapping of the hemagglutinin molecule of a highly pathogenic H5N1 influenza virus by using monoclonal antibodies. J Virol 81: 12911-12917. (Pubitemid 350156928)
21. Khurana S, Suguitan AL Jr., Rivera Y, Simmons CP, Lanzavecchia A, et al. (2009) Antigenic fingerprinting of H5N1 avian influenza using convalescent sera and monoclonal antibodies reveals potential vaccine and diagnostic targets. PLoS Med 6: e1000049. doi:10.1371/ journal.pmed.1000049.
22. Sandbulte MR, Jimenez GS, Boon ACM, Smith LR, Treanor JJ, et al. (2007) Cross-reactive neuraminidase antibodies afford partial protection against H5N1 in mice and are present in unexposed humans. PLoS Med 4: e59. doi:10.1371/journal.pmed.0040059.
23. Fan J, Liang X, Horton MS, Perry HC, Citron MP, et al. (2004) Preclinical study of influenza virus A M2 peptide conjugate vaccines in mice, ferrets, and rhesus monkeys. Vaccine 22: 2993-3003. (Pubitemid 39037199)
24. Feng J, Zhang M, Mozdzanowska K, Zharikova D, Hoff H, et al. (2006) Influenza A virus infection engenders a poor antibody response against the ectodomain of matrix protein 2. Virol J 3: 102.
25. + memory B cells. PLoS ONE 3: e3942. doi:10.1371/journal.pone.0003942.
26. Sui J, Hwang WC, Perez S, Wei G, Aird D, et al. (2009) Structural and functional bases for broadspectrum neutralization of avian and human influenza A viruses. Nat Struct Mol Biol 16: 265-273.
27. Ekiert DC, Bhabha G, Elsliger MA, Friesen RH, Jongeneelen M, et al. (2009) Antibody recognition of a highly conserved influenza virus epitope. Science; E-pub 26 February 2009. doi:10.1126/ science.1171491.