Two influenza A virus-specific fabs neutralize by inhibiting virus attachment to target cells, while neutralization by their IgGs is complex and occurs simultaneously through fusion inhibition and attachment inhibition

Virology

Volumn 278, Issue 2, 2000, Pages 423-435

  Edwards, M J ^a,b   Dimmock, N J ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b EDWARD JENNER INST FOR VACC RES   (United Kingdom)

Author keywords

Affinity; F(ab )2; Fab; IgG; Influenza A virus; Inhibition of attachment; Inhibition of fusion; Inhibition of internalization; Mechanism of neutralization; Neutralization

Indexed keywords

EPITOPE; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G2A; IMMUNOGLOBULIN G3; VIRUS PROTEIN;

ANIMAL CELL; ANTIBODY AFFINITY; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; ARTICLE; BINDING AFFINITY; CELL FUSION; CONCENTRATION RESPONSE; CONTROLLED STUDY; INFLUENZA VIRUS; INHIBITION KINETICS; INTERNALIZATION; NONHUMAN; PRIORITY JOURNAL; TARGET CELL; VIRUS ADSORPTION; VIRUS CELL INTERACTION; VIRUS NEUTRALIZATION;

INFLUENZA A VIRUS; INFLUENZA VIRUS; INFLUENZAVIRUS A;

EID: 0034535166     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.2000.0631     Document Type: Article

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