-
1
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
10.1016/j.cell.2006.10.018, 17081971
-
Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006, 127:469-480. 10.1016/j.cell.2006.10.018, 17081971.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
2
-
-
0026264203
-
DNA-binding properties of the HMG domain of the lymphoid-specific transcriptional regulator LEF-1
-
Giese K, Amsterdam A, Grosschedl R. DNA-binding properties of the HMG domain of the lymphoid-specific transcriptional regulator LEF-1. Genes Dev 1991, 5:267-278.
-
(1991)
Genes Dev
, vol.5
, pp. 267-278
-
-
Giese, K.1
Amsterdam, A.2
Grosschedl, R.3
-
3
-
-
0030896455
-
ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer function
-
10.1101/gad.11.5.640, 9119228
-
Bruhn L, Munnerlyn A, Grosschedl R. ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer function. Genes Dev 1997, 11:640-653. 10.1101/gad.11.5.640, 9119228.
-
(1997)
Genes Dev
, vol.11
, pp. 640-653
-
-
Bruhn, L.1
Munnerlyn, A.2
Grosschedl, R.3
-
4
-
-
0031856533
-
Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin
-
109066, 9671490
-
Hsu SC, Galceran J, Grosschedl R. Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin. Mol Cell Biol 1998, 18:4807-4818. 109066, 9671490.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 4807-4818
-
-
Hsu, S.C.1
Galceran, J.2
Grosschedl, R.3
-
5
-
-
17244376814
-
Wnt signaling in stem cells and cancer
-
10.1038/nature03319, 15829953
-
Reya T, Clevers H. Wnt signaling in stem cells and cancer. Nature 2005, 434:843-850. 10.1038/nature03319, 15829953.
-
(2005)
Nature
, vol.434
, pp. 843-850
-
-
Reya, T.1
Clevers, H.2
-
6
-
-
33846705750
-
Epithelial stem cells: turning over new leaves
-
10.1016/j.cell.2007.01.014, 2408375, 17289566
-
Blanpain C, Horsley V, Fuchs E. Epithelial stem cells: turning over new leaves. Cell 2007, 128:445-458. 10.1016/j.cell.2007.01.014, 2408375, 17289566.
-
(2007)
Cell
, vol.128
, pp. 445-458
-
-
Blanpain, C.1
Horsley, V.2
Fuchs, E.3
-
7
-
-
33745815351
-
Wnt activation and alternative promoter repression of LEF1 in colon cancer
-
Li TW, Ting JH, Yokoyama NN, Bernstein A, van de Wetering M, Waterman ML. Wnt activation and alternative promoter repression of LEF1 in colon cancer. Mol Cell Bio 2006, 26:5284-5299.
-
(2006)
Mol Cell Bio
, vol.26
, pp. 5284-5299
-
-
Li, T.W.1
Ting, J.H.2
Yokoyama, N.N.3
Bernstein, A.4
van de Wetering, M.5
Waterman, M.L.6
-
8
-
-
35648967560
-
PITX2 and beta-catenin interactions regulate Lef-1 isoform expression
-
Amen M, Liu X, Vadlamudi U, Elizondo G, Diamond E, Engelhardt JF, Amendt BA. PITX2 and beta-catenin interactions regulate Lef-1 isoform expression. Mol Cell Bio 2007, 27:7560-7573.
-
(2007)
Mol Cell Bio
, vol.27
, pp. 7560-7573
-
-
Amen, M.1
Liu, X.2
Vadlamudi, U.3
Elizondo, G.4
Diamond, E.5
Engelhardt, J.F.6
Amendt, B.A.7
-
9
-
-
0034192176
-
The human LEF-1 gene contains a promoter preferentially active in lymphocytes and encodes multiple isoforms derived from alternative splicing
-
10.1093/nar/28.9.1994, 103301, 10756202
-
Hovanes K, Li TW, Waterman ML. The human LEF-1 gene contains a promoter preferentially active in lymphocytes and encodes multiple isoforms derived from alternative splicing. Nucleic Acids Res 2000, 28:1994-2003. 10.1093/nar/28.9.1994, 103301, 10756202.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 1994-2003
-
-
Hovanes, K.1
Li, T.W.2
Waterman, M.L.3
-
10
-
-
24044502285
-
An internal ribosome entry site mediates translation of lymphoid enhancer factor-1
-
10.1261/rna.7226105, 1370822, 16120831
-
Jimenez J, Jang GM, Semler BL, Waterman ML. An internal ribosome entry site mediates translation of lymphoid enhancer factor-1. RNA 2005, 11:1385-1399. 10.1261/rna.7226105, 1370822, 16120831.
-
(2005)
RNA
, vol.11
, pp. 1385-1399
-
-
Jimenez, J.1
Jang, G.M.2
Semler, B.L.3
Waterman, M.L.4
-
11
-
-
0030067337
-
Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties
-
231054, 8622675
-
van de Wetering M, Castrop J, Korinek V, Clevers H. Extensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control properties. Mol Cell Biol 1996, 16:745-752. 231054, 8622675.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 745-752
-
-
van de Wetering, M.1
Castrop, J.2
Korinek, V.3
Clevers, H.4
-
12
-
-
0035033521
-
Beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer
-
Hovanes K, Li TW, Munguia JE, Truong T, Milovanovic T, Lawrence Marsh J, Holcombe RF, Waterman ML. Beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer. Nat Genet 2001, 28:53-57.
-
(2001)
Nat Genet
, vol.28
, pp. 53-57
-
-
Hovanes, K.1
Li, T.W.2
Munguia, J.E.3
Truong, T.4
Milovanovic, T.5
Lawrence Marsh, J.6
Holcombe, R.F.7
Waterman, M.L.8
-
13
-
-
0031436939
-
Induction of a beta-catenin-LEF-1 complex by wnt-1 and transforming mutants of beta-catenin
-
10.1038/sj.onc.1201462, 9419974
-
Porfiri E, Rubinfeld B, Albert I, Hovanes K, Waterman M, Polakis P. Induction of a beta-catenin-LEF-1 complex by wnt-1 and transforming mutants of beta-catenin. Oncogene 1997, 15:2833-2839. 10.1038/sj.onc.1201462, 9419974.
-
(1997)
Oncogene
, vol.15
, pp. 2833-2839
-
-
Porfiri, E.1
Rubinfeld, B.2
Albert, I.3
Hovanes, K.4
Waterman, M.5
Polakis, P.6
-
14
-
-
34548313955
-
Clonogenic assay of cells in vitro
-
10.1038/nprot.2006.339, 17406473
-
Franken NA, Rodermond HM, Stap J, Haveman J, van Bree C. Clonogenic assay of cells in vitro. Nat Protoc 2006, 1:2315-2319. 10.1038/nprot.2006.339, 17406473.
-
(2006)
Nat Protoc
, vol.1
, pp. 2315-2319
-
-
Franken, N.A.1
Rodermond, H.M.2
Stap, J.3
Haveman, J.4
van Bree, C.5
-
15
-
-
58249109346
-
Blockade of Notch signaling in tumor-bearing mice may lead to tumor regression, progression, or metastasis, depending on tumor cell types
-
2606116, 19107229
-
Hu XB, Feng F, Wang YC, Wang L, He F, Dou GR, Liang L, Zhang HM, Liang YM, Han H. Blockade of Notch signaling in tumor-bearing mice may lead to tumor regression, progression, or metastasis, depending on tumor cell types. Neoplasia 2009, 11:32-38. 2606116, 19107229.
-
(2009)
Neoplasia
, vol.11
, pp. 32-38
-
-
Hu, X.B.1
Feng, F.2
Wang, Y.C.3
Wang, L.4
He, F.5
Dou, G.R.6
Liang, L.7
Zhang, H.M.8
Liang, Y.M.9
Han, H.10
-
16
-
-
0033711624
-
Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism
-
10.1016/S1074-7613(00)00004-2, 10933391
-
Reya T, O'Riordan M, Okamura R. Wnt signaling regulates B lymphocyte proliferation through a LEF-1 dependent mechanism. Immunity 2000, 13:15-24. 10.1016/S1074-7613(00)00004-2, 10933391.
-
(2000)
Immunity
, vol.13
, pp. 15-24
-
-
Reya, T.1
O'Riordan, M.2
Okamura, R.3
-
17
-
-
34247479498
-
Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion
-
10.1182/blood-2006-12-063933, 1885521, 17311993
-
Scehnet JS, Jiang W, Kumar SR, Krasnoperov V, Trindade A, Benedito R, Djokovic D, Borges C, Ley EJ, Duarte A, Gill PS. Inhibition of Dll4-mediated signaling induces proliferation of immature vessels and results in poor tissue perfusion. Blood 2007, 109:4753-4760. 10.1182/blood-2006-12-063933, 1885521, 17311993.
-
(2007)
Blood
, vol.109
, pp. 4753-4760
-
-
Scehnet, J.S.1
Jiang, W.2
Kumar, S.R.3
Krasnoperov, V.4
Trindade, A.5
Benedito, R.6
Djokovic, D.7
Borges, C.8
Ley, E.J.9
Duarte, A.10
Gill, P.S.11
-
18
-
-
11244305618
-
WNT signaling and haematopoiesis: a WNT-WNT situation
-
10.1038/nri1529, 15630426
-
Staal FJ, Clevers HC. WNT signaling and haematopoiesis: a WNT-WNT situation. Nat Rev Immunol 2005, 5:21-30. 10.1038/nri1529, 15630426.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 21-30
-
-
Staal, F.J.1
Clevers, H.C.2
-
19
-
-
0031883962
-
Redundant regulation of T cell diff erentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1
-
10.1016/S1074-7613(00)80454-9, 9462507
-
Okamura RM, Sigvardsson M, Galceran J, Verbeek S, Clevers H, Grosschedl R. Redundant regulation of T cell diff erentiation and TCRalpha gene expression by the transcription factors LEF-1 and TCF-1. Immunity 1998, 8:11-20. 10.1016/S1074-7613(00)80454-9, 9462507.
-
(1998)
Immunity
, vol.8
, pp. 11-20
-
-
Okamura, R.M.1
Sigvardsson, M.2
Galceran, J.3
Verbeek, S.4
Clevers, H.5
Grosschedl, R.6
-
20
-
-
0032483439
-
Identification of c-MYC as a target of the APC pathway
-
He TC, Sparks AB, Rago C, Hermeking H, Zawel L, da Costa LT, Morin PJ, Vogelstein B, Kinzler KW. Identification of c-MYC as a target of the APC pathway. Science 1998, 281:1509-1512.
-
(1998)
Science
, vol.281
, pp. 1509-1512
-
-
He, T.C.1
Sparks, A.B.2
Rago, C.3
Hermeking, H.4
Zawel, L.5
da Costa, L.T.6
Morin, P.J.7
Vogelstein, B.8
Kinzler, K.W.9
-
21
-
-
0033545845
-
The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway
-
10.1073/pnas.96.10.5522, 21892, 10318916
-
Shtutman M, Zhurinsky J, Simcha I, Albanese C, D'Amico M, Pestell R, Ben-Ze'ev A. The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. Proc Nat. Acad Sci USA 1999, 96:5522-5527. 10.1073/pnas.96.10.5522, 21892, 10318916.
-
(1999)
Proc Nat. Acad Sci USA
, vol.96
, pp. 5522-5527
-
-
Shtutman, M.1
Zhurinsky, J.2
Simcha, I.3
Albanese, C.4
D'Amico, M.5
Pestell, R.6
Ben-Ze'ev, A.7
-
22
-
-
68049131577
-
The SDF-1/CXCR4 axis is a novel driver of vascular development of the glomerulus
-
Floege J, Smeets B, Moeller MJ. The SDF-1/CXCR4 axis is a novel driver of vascular development of the glomerulus. J Am Soc Nephrol 2009, 8:1714-1723.
-
(2009)
J Am Soc Nephrol
, vol.8
, pp. 1714-1723
-
-
Floege, J.1
Smeets, B.2
Moeller, M.J.3
-
23
-
-
70349656338
-
The role of SDF-1/CXCR4 axis in ovarian cancer metastasis
-
10.1007/s11596-009-0320-0, 19513623
-
Shen X, Wang S, Wang H, Liang M, Xiao L, Wang Z. The role of SDF-1/CXCR4 axis in ovarian cancer metastasis. J Huazhong Univ Sci Technol Med Sci 2009, 29:363-367. 10.1007/s11596-009-0320-0, 19513623.
-
(2009)
J Huazhong Univ Sci Technol Med Sci
, vol.29
, pp. 363-367
-
-
Shen, X.1
Wang, S.2
Wang, H.3
Liang, M.4
Xiao, L.5
Wang, Z.6
-
24
-
-
65349158225
-
Increased expression of SDF-1/CXCR4 is associated with lymph node metastasis of invasive micropapillary carcinoma of the breast
-
10.1111/j.1365-2559.2009.03289.x, 19438749
-
Liu F, Lang R, Wei J, Fan Y, Cui L, Gu F, Guo X, Pringle GA, Zhang X, Fu L. Increased expression of SDF-1/CXCR4 is associated with lymph node metastasis of invasive micropapillary carcinoma of the breast. Histopathology 2009, 54:741-750. 10.1111/j.1365-2559.2009.03289.x, 19438749.
-
(2009)
Histopathology
, vol.54
, pp. 741-750
-
-
Liu, F.1
Lang, R.2
Wei, J.3
Fan, Y.4
Cui, L.5
Gu, F.6
Guo, X.7
Pringle, G.A.8
Zhang, X.9
Fu, L.10
-
25
-
-
67649882158
-
Inhibition of the SDF-1/CXCR4 axis attenuates neonatal hypoxia-induced pulmonary hypertension
-
10.1161/CIRCRESAHA.109.197533, 2757744, 19423843
-
Young KC, Torres E, Hatzistergos KE, Hehre D, Suguihara C, Hare JM. Inhibition of the SDF-1/CXCR4 axis attenuates neonatal hypoxia-induced pulmonary hypertension. Circ Res 2009, 104:1293-1301. 10.1161/CIRCRESAHA.109.197533, 2757744, 19423843.
-
(2009)
Circ Res
, vol.104
, pp. 1293-1301
-
-
Young, K.C.1
Torres, E.2
Hatzistergos, K.E.3
Hehre, D.4
Suguihara, C.5
Hare, J.M.6
-
26
-
-
61449451621
-
The CXCR4/SDF-1 chemokine receptor axis: a new target therapeutic for non-small cell lung cancer
-
10.1097/JTO.0b013e31818dda9d, 19057260
-
Otsuka S, Bebb G. The CXCR4/SDF-1 chemokine receptor axis: a new target therapeutic for non-small cell lung cancer. J Thorac Oncol 2008, 3:1379-1383. 10.1097/JTO.0b013e31818dda9d, 19057260.
-
(2008)
J Thorac Oncol
, vol.3
, pp. 1379-1383
-
-
Otsuka, S.1
Bebb, G.2
-
27
-
-
33646353217
-
SDF1α/CXCR4 signaling stimulates β-catenin transcriptional activity in rat neural progenitors
-
10.1016/j.neulet.2006.01.024, 16469439
-
Luo Y, Cai J, Xue H, Mattson MP, Rao MS. SDF1α/CXCR4 signaling stimulates β-catenin transcriptional activity in rat neural progenitors. Neurosci Lett 2006, 398:291-295. 10.1016/j.neulet.2006.01.024, 16469439.
-
(2006)
Neurosci Lett
, vol.398
, pp. 291-295
-
-
Luo, Y.1
Cai, J.2
Xue, H.3
Mattson, M.P.4
Rao, M.S.5
-
28
-
-
34547830895
-
Beta-catenin is a promising key factor in the SDF-1/CXCR4 axis on metastasis of pancreatic cancer
-
10.1016/j.mehy.2007.01.069, 17379424
-
Wang Z, Ma Q. Beta-catenin is a promising key factor in the SDF-1/CXCR4 axis on metastasis of pancreatic cancer. Med Hypotheses 2007, 69:816-820. 10.1016/j.mehy.2007.01.069, 17379424.
-
(2007)
Med Hypotheses
, vol.69
, pp. 816-820
-
-
Wang, Z.1
Ma, Q.2
-
29
-
-
35448988114
-
Molecular targets in pulmonary fibrosis: the myofibroblast in focus
-
10.1378/chest.06-2568, 17934117
-
Scotton CJ, Chambers RC. Molecular targets in pulmonary fibrosis: the myofibroblast in focus. Chest 2007, 132:1311-1321. 10.1378/chest.06-2568, 17934117.
-
(2007)
Chest
, vol.132
, pp. 1311-1321
-
-
Scotton, C.J.1
Chambers, R.C.2
-
30
-
-
67650675165
-
Stromal cell-derived factor-1 promotes survival of pancreatic beta cells by the stabilisation of beta-catenin and activation of transcription factor 7-like 2 (TCF7L2)
-
10.1007/s00125-009-1384-x, 19468708
-
Liu Z, Habener JF. Stromal cell-derived factor-1 promotes survival of pancreatic beta cells by the stabilisation of beta-catenin and activation of transcription factor 7-like 2 (TCF7L2). Diabetologia 2009, 52:1589-1598. 10.1007/s00125-009-1384-x, 19468708.
-
(2009)
Diabetologia
, vol.52
, pp. 1589-1598
-
-
Liu, Z.1
Habener, J.F.2
-
31
-
-
55349084792
-
Wnt/beta-catenin and Fgf signaling control collective cell migration by restricting chemokine receptor expression
-
10.1016/j.devcel.2008.10.002, 19000839
-
Aman A, Piotrowski T. Wnt/beta-catenin and Fgf signaling control collective cell migration by restricting chemokine receptor expression. Dev Cell 2008, 15:749-761. 10.1016/j.devcel.2008.10.002, 19000839.
-
(2008)
Dev Cell
, vol.15
, pp. 749-761
-
-
Aman, A.1
Piotrowski, T.2
-
32
-
-
55949116428
-
Blockade of SDF-1/CXCR4 signalling inhibits pancreatic cancer progression in vitro via inactivation of canonical Wnt pathway
-
10.1038/sj.bjc.6604745, 2584946, 19002187
-
Wang Z, Ma Q, Liu Q, et al. Blockade of SDF-1/CXCR4 signalling inhibits pancreatic cancer progression in vitro via inactivation of canonical Wnt pathway. Br J Cancer 2008, 99:1695-1703. 10.1038/sj.bjc.6604745, 2584946, 19002187.
-
(2008)
Br J Cancer
, vol.99
, pp. 1695-1703
-
-
Wang, Z.1
Ma, Q.2
Liu, Q.3
-
33
-
-
4444322817
-
CXCR4-mediated adhesion and MMP-9 secretion in head and neck squamous cell carcinoma
-
10.1016/j.canlet.2004.04.035, 15363550
-
Samara GJ, Lawrence DM, Chiarelli CJ, Valentino MD, Lyubsky S, Zucker S, Vaday GG. CXCR4-mediated adhesion and MMP-9 secretion in head and neck squamous cell carcinoma. Cancer Lett 2004, 214:231-241. 10.1016/j.canlet.2004.04.035, 15363550.
-
(2004)
Cancer Lett
, vol.214
, pp. 231-241
-
-
Samara, G.J.1
Lawrence, D.M.2
Chiarelli, C.J.3
Valentino, M.D.4
Lyubsky, S.5
Zucker, S.6
Vaday, G.G.7
|