Ligands and signaling proteins govern the conformational landscape explored by a G protein-coupled receptor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 21, 2012, Pages 8304-8309

  Mary, Sophie ^a,b   Damian, Marjorie ^a,b   Louet, Maxime ^a,b   Floquet, Nicolas ^a,b   Fehrentz, Jean Alain ^a,b   Marie, Jacky ^a,b   Martinez, Jean ^a,b   Banères, Jean Louis ^a,b  

^a CNRS   (France)

^b UNIVERSITÉ DE MONTPELLIER   (France)

Author keywords

Biased ligands; Constitutive activity; Membrane protein; Structural repertoire

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GHRELIN; LIPID; MONOMER; RETINA S ANTIGEN;

ARTICLE; CONFORMATIONAL TRANSITION; FLUORESCENCE; FLUORESCENCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN BINDING; SIGNAL TRANSDUCTION;

ARRESTIN; BICYCLO COMPOUNDS, HETEROCYCLIC; DRUG INVERSE AGONISM; FLUORESCENCE; GHRELIN; HUMANS; LIGANDS; MEMBRANE PROTEINS; PROTEIN CONFORMATION; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, GHRELIN; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84861429624     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1119881109     Document Type: Article

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