Inhibition of the sole type I signal peptidase of Mycobacterium tuberculosis is bactericidal under replicating and nonreplicating conditions

Journal of Bacteriology

Volumn 194, Issue 10, 2012, Pages 2614-2619

  Ollinger, J ^a   O'Malley, T ^a   Ahn, J ^a   Odingo, J ^a   Parish, T ^a  

^a INFECTIOUS DISEASE RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2,5 DICHLOROPHENYL) 3 (DIMETHYLAMINO)PROPAN 1 ONE; ANHYDROTETRACYCLINE; LEPB PROTEIN; LYSINE; MD 3; SERINE; SERINE PROTEINASE INHIBITOR; SIGNAL PEPTIDASE I; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GROWTH; BACTERICIDAL ACTIVITY; CELL DIVISION; CELL VIABILITY; CONTROLLED STUDY; CYTOLYSIS; DOWN REGULATION; ENZYME INHIBITION; GENE OVEREXPRESSION; GROWTH INHIBITION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION;

AMINO ACID SEQUENCE; CELL PROLIFERATION; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, BACTERIAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MEMBRANE PROTEINS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MYCOBACTERIUM TUBERCULOSIS; SERINE ENDOPEPTIDASES;

MYCOBACTERIUM TUBERCULOSIS;

EID: 84861380413     PISSN: 00219193     EISSN: 10985530     Source Type: Journal    
DOI: 10.1128/JB.00224-12     Document Type: Article

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