Neuroprotective effect of the aminoestrogen prolame against impairment of learning and memory skills in rats injected with amyloid-β -25-35 into the hippocampus

European Journal of Pharmacology

Volumn 685, Issue 1-3, 2012, Pages 74-80

  Limón, Daniel ^a   Díaz, Alfonso ^a,b   Hernandez, Monserrat ^a   Fernandez G, Juan M ^c   Torres Martínez, Ana C ^d   Pérez Severiano, Francisca ^b   Rendón Huerta, Erika P ^d   Montaño, Luis F ^d   Guevara, Jorge ^d  

^a BENEMÉRITA UNIVERSIDAD AUTÓNOMA DE PUEBLA   (Mexico)

^b NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

^c Universidad Nacional Autonoma de Mexico Facultad de Quimica   (Mexico)

^d UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Alzheimer's disease; Amyloid beta; Lipoperoxidation; Oxidative stress; Prolame

Indexed keywords

AMYLOID BETA PROTEIN[25-35]; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLIAL FIBRILLARY ACIDIC PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; PROLAME; REACTIVE OXYGEN METABOLITE; SESAME SEED OIL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; BRAIN REGION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG RESPONSE; GENE EXPRESSION PROFILING; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LEARNING DISORDER; LIPID PEROXIDATION; MALE; MAZE TEST; MEMORY DISORDER; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TASK PERFORMANCE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; DISEASE MODELS, ANIMAL; ESTRENES; HIPPOCAMPUS; LEARNING DISORDERS; LIPID PEROXIDATION; MALE; MEMORY DISORDERS; NEUROPROTECTIVE AGENTS; NITRIC OXIDE SYNTHASE TYPE I; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES;

EID: 84861341894     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.04.020     Document Type: Article

References (57)

1. S.F. Ali, S.N. David, and G.D. Newport Age-related susceptibility to MPTP-induced neurotoxicity in mice Neurotoxicology 14 1993 29 34
2. O.Y. Bang, H.S. Hong, and D.H. Kim Neuroprotective effect of genistein against beta amyloid-induced neurotoxicity Neurobiol. Dis. 16 2004 21 28
3. K.J. Barnham, C.L. Masters, and A.I. Bush Neurodegenerative diseases and oxidative stress Nat. Rev. Drug Discov. 3 2004 205 214
4. B.R. Bhavnani, M. Berco, and J. Binkley Equine estrogens differentially prevent neuronal cell death induced by glutamate Reprod. Sci. 10 2003 302 308
5. D.A. Butterfield, A. Castegna, C.M. Lauderback, and J. Drake Evidence that amyloid beta-peptide-induced lipid peroxidation and its sequelae in Alzheimer's disease brain contribute to neuronal death Neurobiol. Aging 23 2002 655 664
6. E. Cuevas, D. Limón, F. Pérez-Severiano, A. Díaz, L. Ortega, E. Zenteno, and J. Guevara Antioxidant effects of epicatechin on the hippocampal toxicity caused by amyloid-beta 25-35 in rats Eur. J. Pharmacol. 616 1-3 2009 122 127
7. R.G. Cutler, J. Kelly, K. Storie, W.A. Pedersen, A. Tammara, K. Hatanpaa, J.C. Troncoso, and M.P. Mattson Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease Proc. Natl. Acad. Sci. U. S. A. 101 2004 2070 2075
8. A. De LaPeña, G. Baños, R. Izaguirre, J. Mandoki, and J.M. Fernandez-G Comparative effect of synthetic aminoestrogens with estradiol on platelet aggregation Steroids 58 1993 407 409
9. S. Delobette, A. Privat, and T. Maurice In vitro aggregation facilitates beta-amyloid peptide-(25-35)-induced amnesia in the rat Eur. J. Pharmacol. 319 1997 1 4
10. A. Diaz, L. Mendieta, E. Zenteno, J. Guevara, and I.D. Limon The role of NOS in the impairment of spatial memory and damaged neurons in rats injected with amyloid beta 25-35 in the temporal cortex Pharmacol. Biochem. Behav. 98 2011 67 75
11. B. Drouet, M. Pinçon-Raymond, J. Chambaz, and T. Pillot Molecular basis of Alzheimer's disease Cell. Mol. Life Sci. 57 2000 705 715
12. J.M. Fernandez-G, M.F. Rubio-Arroyo, and M. Soriano-Garcia Synthesis and molecular structure of prolame, (N-(3-hydroxy-1,3,5(10)-estratrien-17β-yl)- 3-hydroxypropylamine). An amino-estrogen with prolonged anticoagulant and brief estrogenic effects Steroids 45 1985 151 157
13. G. Gonzalez, N. Alvarado-Vasquez, J.M. Fernandez-G, D. Cruz-Robles, L. del Valle, E. Pinzon, I. Torres, E. Rodriguez, E. Zapata, V. Gomez-Vidales, L.F. Montaño, and A. de la Peña The antithrombotic effect of the aminoestrogen prolame N-(3-hydroxy-1,3,5(10)-estratrien-17β-yl)-3- hydroxypropylamine) is linked to an increase in nitric oxide production by platelets and endothelial cells Atherosclerosis 208 2010 62 68
14. J. Hardy, and D.J. Selkoe The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics Science 298 2002 962 964
15. V.W. Henderson Action of estrogens in the aging brain: dementia and cognitive aging Biochim. Biophys. Acta 1800 2010 1077 1083
16. K. Iqbal, M. Flory, S. Khatoon, H. Soininen, T. Pirttila, M. Lehtovirta, I. Alafuzoff, K. Blennow, N. Andreasen, E. Vanmechelen, and I. Grundke-Iqbal Subgroups of Alzheimer's disease based on cerebrospinal fluid molecular markers Ann. Neurol. 58 2005 748 757
17. C. Janicki, and N. Schupf Hormonal influences on cognition and risk for Alzheimer's disease Curr. Neurol. Neurosci. Rep. 10 2010 359 366
18. D.G. Jo, T.V. Arumugam, H.N. Woo, J.S. Park, S.C. Tang, M. Mughal, D.H. Hyun, J.H. Park, Y.H. Choi, A.R. Gwon, S. Camandola, A. Cheng, H. Cai, W. Song, W.R. Markesbery, and M.P. Mattson Evidence that gamma-secretase mediates oxidative stressinduced beta-secretase expression in Alzheimer's disease Neurobiol. Aging 6 2008 917 925
19. O. Lekontseva, S. Chakrabarti, Y. Jiang, C.C. Cheung, and S.T. Davidge Role of neuronal nitric-oxide synthase in estrogen-induced relaxation in rat resistance arteries J. Pharmacol. Exp. Ther. 339 2 2011 367 375
20. C. Lemini, Y. Franco, M.E. Avila, and R. Jaimez Contrasting effects of estradiol and 17 beta-aminoestrogens on blood clotting time in rats and mice Eur. J. Pharmacol. 510 3 2005 229 233
21. K. Liang, L. Yang, C. Yin, Z. Xiao, J. Zhang, Y. Liu, and J. Huang Estrogen stimulates degradation of b-amyloid peptide by up-regulating neprilysin J. Biol. Chem. 285 2010 935 942
22. I.D. Limón, A. Díaz, L. Mendieta, G. Chamorro, B. Espinosa, E. Zenteno, and J. Guevara Amyloid-beta(25-35) impairs memory and increases NO in the temporal cortex of rats Neurosci. Res. 63 2009 129 137
23. I.D. Limón, L. Mendieta, A. Díaz, G. Chamorro, B. Espinosa, E. Zenteno, and J. Guevara Neuroprotective effect of alpha-asarone on spatial memory and nitric oxide levels in rats injected with amyloid-beta(25-35) Neurosci. Lett. 453 2009 98 103
24. T. Lynch, R.A. Cherny, and A.I. Bush Oxidative processes in Alzheimer's disease: the role of abeta-metal interactions Exp. Gerontol. 35 2000 445 451
25. S. Mandrekar-Colucci, and G.E. Landreth Microglia and inflammation in Alzheimer's disease CNS Neurol. Disord. Drug Targets 9 2010 156 167
26. M.P. Mattson Oxidative stress, perturbed calcium homeostasis, and immune dysfunction in Alzheimer's disease J. Neurovirol. 8 2002 539 550
27. M.P. Mattson, M. Gleichmann, and A. Cheng Mitochondria in neuroplasticity and neurological disorders Neuron 60 2008 748 766
28. T. Maurice, B.P. Lockhart, and A. Privat Amnesia induced in mice by centrally administered beta-amyloid peptides involves cholinergic dysfunction Brain Res. 706 1996 181 193
29. P.L. McGeer, and E.G. McGeer Local neuroinflammation and the progression of Alzheimer's disease J. Neurovirol. 8 2002 529 538
30. P.I. Moreira, A. Nunomura, M. Nakamura, A. Takeda, J.C. Shenk, G. Aliev, M.A. Smith, and G. Perry Nucleic acid oxidation in Alzheimer disease Free Radic. Biol. Med. 44 2008 1493 1505
31. J. Nilsen, S. Chen, R.W. Irwin, S. Iwamoto, and R.D. Brinton Estrogen protects neuronal cells from amyloid beta-induced apoptosis via regulation of mitochondrial proteins and function BMC Neurosci. 7 2006 74 PMID: 17083736
32. D.S. Olton Spatial memory Sci. Am. 236 1977 82 84 89- 94; 96; 98
33. M.S. Parihar, and T. Hemnani Alzheimer's disease pathogenesis and therapeutic interventions J. Clin. Neurosci. 11 2004 456 467
34. G. Paxinos, and C. Watson Hippocampal fissure G. Paxinos, C. Watson, The rat Brain in Stereotaxic Coordinates 1997 Academic Press 30 46
35. F. Pérez-Severiano, S.R. Salvatierra, P.M. Rodríguez, M.E. Cuevas, J. Guevara, D. Limon, D.P. Maldonado, C.O. Medina, C.J. Pedraza, and A. Santamaría S-allylcysteine prevents amyloid-ß peptide-induced oxidative stress in rat hippocampus and ameliorates learning deficits Eur. J. Pharmacol. 489 2004 197 202
36. C.J. Pike, A.J. Walencewicz-Wasserman, J. Kosmoski, D.H. Cribbs, C.G. Glabe, and C.W. Cotman Structure-activity analyses of beta-amyloid peptides: contributions of the beta 25-35 region to aggregation and neurotoxicity J. Neurochem. 64 1995 253 265
37. A. Probst, M.C. Herzig, C. Mistl, S. Ipsen, and M. Tolnay Perisomatic granules (non-plaque dystrophic dendrites) of hippocampal CA1 neurons in Alzheimer's disease and Pick's disease: a lesion distinct from granulovacuolar degeneration Acta Neuropathol. 102 2001 636 644
38. M.B. Ruiz-Larrea, C. Martin, R. Martinez, R. Navarro, M. Lacort, and N.J. Miller Antioxidant activities of estrogens against aqueous and lipophilic radicals; differences between phenol and catechol estrogens Chem. Phys. Lipids 105 2000 179 188
39. T.E. Saez, M. Pehar, M. Vargas, L. Barbeito, and R.B. Maccioni Astrocytic nitric oxide triggers tau hyperphosphorylation in hippocampal neurons In Vivo 18 2004 275 280
40. G. Saravanan, and J. Prakash Effect of garlic (Allium sativum) on lipid peroxidation in experimental myocardial infarction in rats J. Ethnopharmacol. 94 2004 155 158
41. M. Secer, I. Sinici, A. Heper, M.F. Ergungor, and H. Ergun Beta-estradiol reduices lipid peroxidation and depth of injury in cold-induced brain injury model Brain Res. 1345 2010 190 196
42. D.J. Selkoe Toward a comprehensive theory for Alzheimer's disease. Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein Ann. N. Y. Acad. Sci. 924 2000 17 25
43. X.L. Shang, J.H. Zhao, Y.P. Cao, and Y.X. Xue Effects of synaptic plasticity regulated by 17 beta-estradiol on learning and memory in rats with Alzheimer's disease Neurosci. Bull. 26 2010 133 139
44. P.J. Shughrue, M.V. Lane, and L. Merchanteler Comparative distribution of estrogen receptor-a and -b mRNA in the rat central nervous system J. Comp. Neurol. 388 1997 507 525
45. M.Y. Stepanichev, I.M. Zdobnova, I.I. Zarubenko, Y.V. Moiseeva, N.A. Lazareva, M.V. Onufriev, and N.V. Gulyaeva Amyloid-beta(25-35)-induced memory impairments correlate with cell loss in rat hippocampus Physiol. Behav. 80 2004 647 655
46. E. Storey, G.J. Kinsella, and M.J. Slavin The neuropsychological diagnosis of Alzheimer's disease J. Alzheimers Dis. 3 2001 261 285
47. G. Thinakaran, and E.H. Koo Amyloid precursor protein trafficking, processing, and function J. Biol. Chem. 283 2008 29615 29619
48. Y. Tomidokoro, K. Ishiguro, Y. Harigaya, E. Matsubara, M. Ikeda, J.M. Park, K. Yasutake, T. Kawarabayashi, K. Okamoto, and M. Shoji Abeta amyloidosis induces the initial stage of tau accumulation in APP(Sw) mice Neurosci. Lett. 299 2001 169 172
49. M. Ulas, and M. Cay The effects of 17 beta-estradiol and vitamin E treatments on oxidative stress and antioxidant levels in brain cortex of diabetic ovariectomized rats Acta Physiol. Hung. 97 2010 208 215
50. F.J. Vajda Neuroprotection and neurodegenerative disease J. Clin. Neurosci. 9 2002 4 8
51. C.N. Wang, C.W. Chi, and Y.L. Lin The neuroprotective effects of phytoestrogens on amyloid b protein-induced toxicity are mediated by abrogating the activation of caspase cascade in rat cortical neurons J. Biol. Chem. 276 2001 5287 5295
52. D.S. Wang, D.W. Dickson, and J.S. Malter Beta-amyloid degradation and Alzheimer's disease J. Biomed. Biotechnol. 20006 2006 58406
53. H.M. Wisniewski, J. Wegiel, and L. Kotula Some neuropathological aspects of Alzheimer's disease and its relevance to other disciplines Neuropathol. Appl. Neurobiol. 22 1996 3 11
54. T. Wyss-Coray, and L. Mucke Inflammation in neurodegenerative disease - a double-edged sword Neuron 35 2002 419 432
55. B.A. Yankner Amyloid and Alzheimer's disease cause or effect? Neurobiol. Aging 10 1989 470 471
56. B.A. Yankner, L.R. Dawes, S. Fisher, L. Villa-Komaroff, M.L. Oster-Granite, and R.L. Neve Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease Science 245 1989 417 420
57. H. Zheng, H. Xu, S.N. Uljon, R. Gross, K. Hardy, J. Gaynor, J. Lafrancois, J. Simpkins, L.M. Refolo, S. Petanceska, R. Wang, and K. Duff Modulation of A(beta) peptides by estrogen in mouse models J. Neurochem. 80 2002 191 196