메뉴 건너뛰기




Volumn 14, Issue 3, 2012, Pages

Aberrant CD200/CD200R1 expression and function in systemic lupus erythematosus contributes to abnormal T-cell responsiveness and dendritic cell activity

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYFLUORESCEIN DIACETATE SUCCINIMIDYL ESTER; CD200 ANTIGEN; CD200 RECEPTOR; CD200 RECEPTOR 1; LIPOCORTIN 5; PROPIDIUM IODIDE; UNCLASSIFIED DRUG; ANTIGENS, CD200; CD200R1 PROTEIN, HUMAN; CELL SURFACE RECEPTOR; LEUKOCYTE ANTIGEN; MEMBRANE ANTIGEN;

EID: 84861335885     PISSN: 14786354     EISSN: 14786362     Source Type: Journal    
DOI: 10.1186/ar3853     Document Type: Article
Times cited : (32)

References (45)
  • 1
    • 40049093765 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • 10.1056/NEJMra071297, 18305268
    • Rahman A, Isenberg DA. Systemic lupus erythematosus. N Engl J Med 2008, 358:929-939. 10.1056/NEJMra071297, 18305268.
    • (2008) N Engl J Med , vol.358 , pp. 929-939
    • Rahman, A.1    Isenberg, D.A.2
  • 3
    • 0031838606 scopus 로고    scopus 로고
    • Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus
    • 10.1002/1529-0131(199807)41:7<1241::AID-ART15>3.0.CO;2-H, 9663482
    • Herrmann M, Voll RE, Zoller OM, Hagenhofer M, Ponner BB, Kalden JR. Impaired phagocytosis of apoptotic cell material by monocyte-derived macrophages from patients with systemic lupus erythematosus. Arthritis Rheum 1998, 41:1241-1250. 10.1002/1529-0131(199807)41:7<1241::AID-ART15>3.0.CO;2-H, 9663482.
    • (1998) Arthritis Rheum , vol.41 , pp. 1241-1250
    • Herrmann, M.1    Voll, R.E.2    Zoller, O.M.3    Hagenhofer, M.4    Ponner, B.B.5    Kalden, J.R.6
  • 4
    • 0028330345 scopus 로고
    • Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus
    • Emlen W, Niebur J, Kadera R. Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus. J Immunol 1994, 152:3685-3692.
    • (1994) J Immunol , vol.152 , pp. 3685-3692
    • Emlen, W.1    Niebur, J.2    Kadera, R.3
  • 5
    • 0031884870 scopus 로고    scopus 로고
    • High levels of circulating early apoptic peripheral blood mononuclear cells in systemic lupus erythematosus
    • 10.1191/096120398678919804, 9541096
    • Perniok A, Wedekind F, Herrmann M, Specker C, Schneider M. High levels of circulating early apoptic peripheral blood mononuclear cells in systemic lupus erythematosus. Lupus 1998, 7:113-118. 10.1191/096120398678919804, 9541096.
    • (1998) Lupus , vol.7 , pp. 113-118
    • Perniok, A.1    Wedekind, F.2    Herrmann, M.3    Specker, C.4    Schneider, M.5
  • 6
    • 0036164008 scopus 로고    scopus 로고
    • Impaired uptake of apoptotic cells into tingible body macrophages in germinal centers of patients with systemic lupus erythematosus
    • 10.1002/1529-0131(200201)46:1<191::AID-ART10027>3.0.CO;2-K, 11817590
    • Baumann I, Kolowos W, Voll RE, Manger B, Gaipl U, Neuhuber WL, Kirchner T, Kalden JR, Herrmann M. Impaired uptake of apoptotic cells into tingible body macrophages in germinal centers of patients with systemic lupus erythematosus. Arthritis Rheum 2002, 46:191-201. 10.1002/1529-0131(200201)46:1<191::AID-ART10027>3.0.CO;2-K, 11817590.
    • (2002) Arthritis Rheum , vol.46 , pp. 191-201
    • Baumann, I.1    Kolowos, W.2    Voll, R.E.3    Manger, B.4    Gaipl, U.5    Neuhuber, W.L.6    Kirchner, T.7    Kalden, J.R.8    Herrmann, M.9
  • 7
    • 36249024247 scopus 로고    scopus 로고
    • Regulatory T cells - a brief history and perspective
    • Sakaguchi S, Wing K, Miyara M. Regulatory T cells - a brief history and perspective. Eur J Immunol 2007, 37(Suppl 1):S116-S123.
    • (2007) Eur J Immunol , vol.37 , Issue.SUPPL. 1
    • Sakaguchi, S.1    Wing, K.2    Miyara, M.3
  • 8
    • 16844365788 scopus 로고    scopus 로고
    • Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
    • Sakaguchi S. Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self. Nat Immunol 2005, 6:345-352.
    • (2005) Nat Immunol , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 9
    • 62349128189 scopus 로고    scopus 로고
    • Regulatory T cells in systemic lupus erythematosus: past, present and future
    • 10.1186/ar2511, 2656253, 19040771
    • Horwitz DA. Regulatory T cells in systemic lupus erythematosus: past, present and future. Arthritis Res Ther 2008, 10:227. 10.1186/ar2511, 2656253, 19040771.
    • (2008) Arthritis Res Ther , vol.10 , pp. 227
    • Horwitz, D.A.1
  • 11
    • 0021222058 scopus 로고
    • Localisation of the MRC OX-2 glycoprotein on the surfaces of neurones
    • 10.1111/j.1471-4159.1984.tb12844.x, 6147390
    • Webb M, Barclay AN. Localisation of the MRC OX-2 glycoprotein on the surfaces of neurones. J Neurochem 1984, 43:1061-1067. 10.1111/j.1471-4159.1984.tb12844.x, 6147390.
    • (1984) J Neurochem , vol.43 , pp. 1061-1067
    • Webb, M.1    Barclay, A.N.2
  • 12
    • 0020446606 scopus 로고
    • Purification and chemical characterisation of membrane glycoproteins from rat thymocytes and brain, recognised by monoclonal antibody MRC OX 2
    • 10.1111/j.1432-1033.1982.tb07070.x, 6129975
    • Barclay AN, Ward HA. Purification and chemical characterisation of membrane glycoproteins from rat thymocytes and brain, recognised by monoclonal antibody MRC OX 2. Eur J Biochem 1982, 129:447-458. 10.1111/j.1432-1033.1982.tb07070.x, 6129975.
    • (1982) Eur J Biochem , vol.129 , pp. 447-458
    • Barclay, A.N.1    Ward, H.A.2
  • 13
    • 0020672437 scopus 로고
    • The localization of Thy-1.1, MRC OX 2 and Ia antigens in the rat ovary and fallopian tube
    • 1454039, 6131030
    • Bukovsky A, Presl J, Zidovsky J, Mancal P. The localization of Thy-1.1, MRC OX 2 and Ia antigens in the rat ovary and fallopian tube. Immunology 1983, 48:587-596. 1454039, 6131030.
    • (1983) Immunology , vol.48 , pp. 587-596
    • Bukovsky, A.1    Presl, J.2    Zidovsky, J.3    Mancal, P.4
  • 14
    • 2942597759 scopus 로고    scopus 로고
    • CD200 is a ligand for all members of the CD200R family of immunoregulatory molecules
    • Gorczynski R, Chen Z, Kai Y, Lee L, Wong S, Marsden PA. CD200 is a ligand for all members of the CD200R family of immunoregulatory molecules. J Immunol 2004, 172:7744-7749.
    • (2004) J Immunol , vol.172 , pp. 7744-7749
    • Gorczynski, R.1    Chen, Z.2    Kai, Y.3    Lee, L.4    Wong, S.5    Marsden, P.A.6
  • 15
    • 35548979999 scopus 로고    scopus 로고
    • The inhibitory CD200R is differentially expressed on human and mouse T and B lymphocytes
    • 10.1016/j.molimm.2007.07.013, 17714785
    • Rijkers ES, de Ruiter T, Baridi A, Veninga H, Hoek RM, Meyaard L. The inhibitory CD200R is differentially expressed on human and mouse T and B lymphocytes. Mol Immunol 2008, 45:1126-1135. 10.1016/j.molimm.2007.07.013, 17714785.
    • (2008) Mol Immunol , vol.45 , pp. 1126-1135
    • Rijkers, E.S.1    de Ruiter, T.2    Baridi, A.3    Veninga, H.4    Hoek, R.M.5    Meyaard, L.6
  • 19
    • 0036841128 scopus 로고    scopus 로고
    • Constitutive retinal CD200 expression regulates resident microglia and activation state of inflammatory cells during experimental autoimmune uveoretinitis
    • 10.1016/S0002-9440(10)64444-6, 1850781, 12414514
    • Broderick C, Hoek RM, Forrester JV, Liversidge J, Sedgwick JD, Dick AD. Constitutive retinal CD200 expression regulates resident microglia and activation state of inflammatory cells during experimental autoimmune uveoretinitis. Am J Pathol 2002, 161:1669-1677. 10.1016/S0002-9440(10)64444-6, 1850781, 12414514.
    • (2002) Am J Pathol , vol.161 , pp. 1669-1677
    • Broderick, C.1    Hoek, R.M.2    Forrester, J.V.3    Liversidge, J.4    Sedgwick, J.D.5    Dick, A.D.6
  • 20
    • 6344225337 scopus 로고    scopus 로고
    • Expression of CD200 on epithelial cells of the murine hair follicle: a role in tissue-specific immune tolerance?
    • 10.1111/j.0022-202X.2004.23461.x, 15482475
    • Rosenblum MD, Olasz EB, Yancey KB, Woodliff JE, Lazarova Z, Gerber KA, Truitt RL. Expression of CD200 on epithelial cells of the murine hair follicle: a role in tissue-specific immune tolerance?. J Invest Dermatol 2004, 123:880-887. 10.1111/j.0022-202X.2004.23461.x, 15482475.
    • (2004) J Invest Dermatol , vol.123 , pp. 880-887
    • Rosenblum, M.D.1    Olasz, E.B.2    Yancey, K.B.3    Woodliff, J.E.4    Lazarova, Z.5    Gerber, K.A.6    Truitt, R.L.7
  • 21
    • 77956187111 scopus 로고    scopus 로고
    • Breast cancer cell CD200 expression regulates immune response to EMT6 tumor cells in mice
    • 10.1007/s10549-009-0667-8, 19953316
    • Gorczynski RM, Chen Z, Diao J, Khatri I, Wong K, Yu K, Behnke J. Breast cancer cell CD200 expression regulates immune response to EMT6 tumor cells in mice. Breast Cancer Res Treat 2010, 123:405-415. 10.1007/s10549-009-0667-8, 19953316.
    • (2010) Breast Cancer Res Treat , vol.123 , pp. 405-415
    • Gorczynski, R.M.1    Chen, Z.2    Diao, J.3    Khatri, I.4    Wong, K.5    Yu, K.6    Behnke, J.7
  • 22
    • 37349071767 scopus 로고    scopus 로고
    • CD200: a putative therapeutic target in cancer
    • 10.1016/j.bbrc.2007.11.103, 18060862
    • Moreaux J, Veyrune JL, Reme T, De Vos J, Klein B. CD200: a putative therapeutic target in cancer. Biochem Biophys Res Commun 2008, 366:117-122. 10.1016/j.bbrc.2007.11.103, 18060862.
    • (2008) Biochem Biophys Res Commun , vol.366 , pp. 117-122
    • Moreaux, J.1    Veyrune, J.L.2    Reme, T.3    De Vos, J.4    Klein, B.5
  • 23
    • 0033572270 scopus 로고    scopus 로고
    • Down-regulation of nuclear factor kappaB is required for p53-dependent apoptosis in X-ray-irradiated mouse lymphoma cells and thymocytes
    • Kawai H, Yamada Y, Tatsuka M, Niwa O, Yamamoto K, Suzuki F. Down-regulation of nuclear factor kappaB is required for p53-dependent apoptosis in X-ray-irradiated mouse lymphoma cells and thymocytes. Cancer Res 1999, 59:6038-6041.
    • (1999) Cancer Res , vol.59 , pp. 6038-6041
    • Kawai, H.1    Yamada, Y.2    Tatsuka, M.3    Niwa, O.4    Yamamoto, K.5    Suzuki, F.6
  • 24
    • 0027488020 scopus 로고
    • Identification and quantitation of apoptotic cells following anti-CD3 activation of murine G0 T cells
    • 10.1002/cyto.990140806, 7507023
    • Chrest FJ, Buchholz MA, Kim YH, Kwon TK, Nordin AA. Identification and quantitation of apoptotic cells following anti-CD3 activation of murine G0 T cells. Cytometry 1993, 14:883-890. 10.1002/cyto.990140806, 7507023.
    • (1993) Cytometry , vol.14 , pp. 883-890
    • Chrest, F.J.1    Buchholz, M.A.2    Kim, Y.H.3    Kwon, T.K.4    Nordin, A.A.5
  • 25
    • 0035045748 scopus 로고    scopus 로고
    • Flow cytometry in analysis of cell cycle and apoptosis
    • 10.1016/S0037-1963(01)90051-4, 11309699
    • Darzynkiewicz Z, Bedner E, Smolewski P. Flow cytometry in analysis of cell cycle and apoptosis. Semin Hematol 2001, 38:179-193. 10.1016/S0037-1963(01)90051-4, 11309699.
    • (2001) Semin Hematol , vol.38 , pp. 179-193
    • Darzynkiewicz, Z.1    Bedner, E.2    Smolewski, P.3
  • 26
    • 77954127754 scopus 로고    scopus 로고
    • Essential roles for Dok2 and RasGAP in CD200 receptor-mediated regulation of human myeloid cells
    • Mihrshahi R, Barclay AN, Brown MH. Essential roles for Dok2 and RasGAP in CD200 receptor-mediated regulation of human myeloid cells. J Immunol 2009, 83:4879-4886.
    • (2009) J Immunol , vol.83 , pp. 4879-4886
    • Mihrshahi, R.1    Barclay, A.N.2    Brown, M.H.3
  • 27
    • 0033178938 scopus 로고    scopus 로고
    • An immunoadhesin incorporating the molecule OX-2 is a potent immunosuppressant that prolongs allo- and xenograft survival
    • Gorczynski RM, Cattral MS, Chen Z, Hu J, Lei J, Min WP, Yu G, Ni J. An immunoadhesin incorporating the molecule OX-2 is a potent immunosuppressant that prolongs allo- and xenograft survival. J Immunol 1999, 163:1654-1660.
    • (1999) J Immunol , vol.163 , pp. 1654-1660
    • Gorczynski, R.M.1    Cattral, M.S.2    Chen, Z.3    Hu, J.4    Lei, J.5    Min, W.P.6    Yu, G.7    Ni, J.8
  • 28
    • 0035206952 scopus 로고    scopus 로고
    • CD200 immunoadhesin suppresses collagen-induced arthritis in mice
    • 10.1006/clim.2001.5117, 11726225
    • Gorczynski RM, Chen Z, Yu K, Hu J. CD200 immunoadhesin suppresses collagen-induced arthritis in mice. Clin Immunol 2001, 101:328-334. 10.1006/clim.2001.5117, 11726225.
    • (2001) Clin Immunol , vol.101 , pp. 328-334
    • Gorczynski, R.M.1    Chen, Z.2    Yu, K.3    Hu, J.4
  • 29
    • 0348223787 scopus 로고    scopus 로고
    • Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
    • 10.1084/jem.20030152, 2194145, 14676299
    • Chen W, Jin W, Hardegen N, Lei KJ, Li L, Marinos N, McGrady G, Wahl SM. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med 2003, 198:1875-1886. 10.1084/jem.20030152, 2194145, 14676299.
    • (2003) J Exp Med , vol.198 , pp. 1875-1886
    • Chen, W.1    Jin, W.2    Hardegen, N.3    Lei, K.J.4    Li, L.5    Marinos, N.6    McGrady, G.7    Wahl, S.M.8
  • 30
    • 0142072318 scopus 로고    scopus 로고
    • Increased apoptotic neutrophils and macrophages and impaired macrophage phagocytic clearance of apoptotic neutrophils in systemic lupus erythematosus
    • 10.1002/art.11237, 14558095
    • Ren Y, Tang J, Mok MY, Chan AW, Wu A, Lau CS. Increased apoptotic neutrophils and macrophages and impaired macrophage phagocytic clearance of apoptotic neutrophils in systemic lupus erythematosus. Arthritis Rheum 2003, 48:2888-2897. 10.1002/art.11237, 14558095.
    • (2003) Arthritis Rheum , vol.48 , pp. 2888-2897
    • Ren, Y.1    Tang, J.2    Mok, M.Y.3    Chan, A.W.4    Wu, A.5    Lau, C.S.6
  • 31
    • 77957012651 scopus 로고    scopus 로고
    • The role of dendritic cells in the pathogenesis of systemic lupus erythematosus
    • 10.1186/ar2966, 2888204, 20423534
    • Fransen JH, van der Vlag J, Ruben J, Adema GJ, Berden JH, Hilbrands LB. The role of dendritic cells in the pathogenesis of systemic lupus erythematosus. Arthritis Res Ther 2010, 12:207. 10.1186/ar2966, 2888204, 20423534.
    • (2010) Arthritis Res Ther , vol.12 , pp. 207
    • Fransen, J.H.1    van der Vlag, J.2    Ruben, J.3    Adema, G.J.4    Berden, J.H.5    Hilbrands, L.B.6
  • 32
    • 17544364539 scopus 로고    scopus 로고
    • Lymphocyte apoptosis and macrophage function: correlation with disease activity in systemic lupus erythematosus
    • 10.1007/s10067-004-0972-x, 15818511
    • Jin O, Sun LY, Zhou KX, Zhang XS, Feng XB, Mok MY, Lau CS. Lymphocyte apoptosis and macrophage function: correlation with disease activity in systemic lupus erythematosus. Clin Rheumatol 2005, 24:107-110. 10.1007/s10067-004-0972-x, 15818511.
    • (2005) Clin Rheumatol , vol.24 , pp. 107-110
    • Jin, O.1    Sun, L.Y.2    Zhou, K.X.3    Zhang, X.S.4    Feng, X.B.5    Mok, M.Y.6    Lau, C.S.7
  • 33
    • 0032898385 scopus 로고    scopus 로고
    • Increased apoptotic peripheral blood neutrophils in systemic lupus erythematosus: relations with disease activity, antibodies to double stranded DNA, and neutropenia
    • 10.1136/ard.58.5.309, 1752888, 10225817
    • Courtney PA, Crockard AD, Williamson K, Irvine AE, Kennedy RJ, Bell AL. Increased apoptotic peripheral blood neutrophils in systemic lupus erythematosus: relations with disease activity, antibodies to double stranded DNA, and neutropenia. Ann Rheum Dis 1999, 58:309-314. 10.1136/ard.58.5.309, 1752888, 10225817.
    • (1999) Ann Rheum Dis , vol.58 , pp. 309-314
    • Courtney, P.A.1    Crockard, A.D.2    Williamson, K.3    Irvine, A.E.4    Kennedy, R.J.5    Bell, A.L.6
  • 34
    • 7244240713 scopus 로고    scopus 로고
    • HIV-1-infected dendritic cells up-regulate cell surface markers but fail to produce IL-12 p70 in response to CD40 ligand stimulation
    • 10.1182/blood-2003-07-2314, 15231570
    • Smed-Sorensen A, Lore K, Walther-Jallow L, Andersson J, Spetz AL. HIV-1-infected dendritic cells up-regulate cell surface markers but fail to produce IL-12 p70 in response to CD40 ligand stimulation. Blood 2004, 104:2810-2817. 10.1182/blood-2003-07-2314, 15231570.
    • (2004) Blood , vol.104 , pp. 2810-2817
    • Smed-Sorensen, A.1    Lore, K.2    Walther-Jallow, L.3    Andersson, J.4    Spetz, A.L.5
  • 36
    • 36448961645 scopus 로고    scopus 로고
    • Engulfment of apoptotic cells: signals for a good meal
    • 10.1038/nri2214, 18037898
    • Ravichandran KS, Lorenz U. Engulfment of apoptotic cells: signals for a good meal. Nat Rev Immunol 2007, 7:964-974. 10.1038/nri2214, 18037898.
    • (2007) Nat Rev Immunol , vol.7 , pp. 964-974
    • Ravichandran, K.S.1    Lorenz, U.2
  • 38
    • 58549108182 scopus 로고    scopus 로고
    • Disruption of T cell suppression in chronic lymphocytic leukemia by CD200 blockade
    • 10.1016/j.leukres.2008.08.021, 18838168
    • Pallasch CP, Ulbrich S, Brinker R, Hallek M, Uger RA, Wendtner CM. Disruption of T cell suppression in chronic lymphocytic leukemia by CD200 blockade. Leuk Res 2009, 33:460-464. 10.1016/j.leukres.2008.08.021, 18838168.
    • (2009) Leuk Res , vol.33 , pp. 460-464
    • Pallasch, C.P.1    Ulbrich, S.2    Brinker, R.3    Hallek, M.4    Uger, R.A.5    Wendtner, C.M.6
  • 39
    • 14044259353 scopus 로고    scopus 로고
    • Augmented induction of CD4+CD25+ Treg using monoclonal antibodies to CD200R
    • 10.1097/01.TP.0000152118.51622.F9, 15880066
    • Gorczynski RM, Lee L, Boudakov I. Augmented induction of CD4+CD25+ Treg using monoclonal antibodies to CD200R. Transplantation 2005, 79:1180-1183. 10.1097/01.TP.0000152118.51622.F9, 15880066.
    • (2005) Transplantation , vol.79 , pp. 1180-1183
    • Gorczynski, R.M.1    Lee, L.2    Boudakov, I.3
  • 40
    • 68949122837 scopus 로고    scopus 로고
    • Expression of TGFβ1 and its signaling components by peripheral lymphocytes in systemic lupus erythematosus
    • 10.1007/s12253-008-9119-8, 19020994
    • Kohut E, Hajdu M, Gergely P, Gopcsa L, Kilian K, Paloczi K, Kopper L, Sebestyen A. Expression of TGFβ1 and its signaling components by peripheral lymphocytes in systemic lupus erythematosus. Pathol Oncol Res 2009, 15:251-256. 10.1007/s12253-008-9119-8, 19020994.
    • (2009) Pathol Oncol Res , vol.15 , pp. 251-256
    • Kohut, E.1    Hajdu, M.2    Gergely, P.3    Gopcsa, L.4    Kilian, K.5    Paloczi, K.6    Kopper, L.7    Sebestyen, A.8
  • 41
    • 65549115862 scopus 로고    scopus 로고
    • Plasticity of CD4+ T cell lineage differentiation
    • 10.1016/j.immuni.2009.05.001, 19464987
    • Zhou L, Chong MM, Littman DR. Plasticity of CD4+ T cell lineage differentiation. Immunity 2009, 30:646-655. 10.1016/j.immuni.2009.05.001, 19464987.
    • (2009) Immunity , vol.30 , pp. 646-655
    • Zhou, L.1    Chong, M.M.2    Littman, D.R.3
  • 42
    • 73849110167 scopus 로고    scopus 로고
    • Heterogeneity and plasticity of T helper cells
    • 10.1038/cr.2009.138, 20010916
    • Zhu J, Paul WE. Heterogeneity and plasticity of T helper cells. Cell Res 2010, 20:4-12. 10.1038/cr.2009.138, 20010916.
    • (2010) Cell Res , vol.20 , pp. 4-12
    • Zhu, J.1    Paul, W.E.2
  • 43
    • 11144234182 scopus 로고    scopus 로고
    • CD200 receptor family members represent novel DAP12-associated activating receptors on basophils and mast cells
    • 10.1074/jbc.M406997200, 15471863
    • Voehringer D, Rosen DB, Lanier LL, Locksley RM. CD200 receptor family members represent novel DAP12-associated activating receptors on basophils and mast cells. J Biol Chem 2004, 279:54117-54123. 10.1074/jbc.M406997200, 15471863.
    • (2004) J Biol Chem , vol.279 , pp. 54117-54123
    • Voehringer, D.1    Rosen, D.B.2    Lanier, L.L.3    Locksley, R.M.4
  • 44
    • 33646347896 scopus 로고    scopus 로고
    • Thymocyte/splenocyte-derived CD4+CD25+Treg stimulated by anti-CD200R2 derived dendritic cells suppress mixed leukocyte cultures and skin graft rejection
    • 10.1097/01.tp.0000214984.65520.50, 16612280
    • Gorczynski RM. Thymocyte/splenocyte-derived CD4+CD25+Treg stimulated by anti-CD200R2 derived dendritic cells suppress mixed leukocyte cultures and skin graft rejection. Transplantation 2006, 81:1027-1034. 10.1097/01.tp.0000214984.65520.50, 16612280.
    • (2006) Transplantation , vol.81 , pp. 1027-1034
    • Gorczynski, R.M.1
  • 45
    • 2342479819 scopus 로고    scopus 로고
    • Induction of tolerance-inducing antigen-presenting cells in bone marrow cultures in vitro using monoclonal antibodies to CD200R
    • 10.1097/01.TP.0000121773.18476.1C, 15114074
    • Gorczynski RM, Chen Z, Kai Y, Wong S, Lee L. Induction of tolerance-inducing antigen-presenting cells in bone marrow cultures in vitro using monoclonal antibodies to CD200R. Transplantation 2004, 77:1138-1144. 10.1097/01.TP.0000121773.18476.1C, 15114074.
    • (2004) Transplantation , vol.77 , pp. 1138-1144
    • Gorczynski, R.M.1    Chen, Z.2    Kai, Y.3    Wong, S.4    Lee, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.