-
1
-
-
79251493453
-
The amazing osteocyte
-
Bonewald LF. The amazing osteocyte. J Bone Miner Res. 2011;26(2):229-38.
-
(2011)
J Bone Miner Res.
, vol.26
, Issue.2
, pp. 229-238
-
-
Bonewald, L.F.1
-
2
-
-
80053978532
-
Matrix-embedded cells control osteoclast formation
-
Xiong J, Onal M, Jilka RL, Weinstein RS, Manolagas SC, O'Brien CA. Matrix-embedded cells control osteoclast formation. Nat Med. 2011;17(10):1235-41.
-
(2011)
Nat Med.
, vol.17
, Issue.10
, pp. 1235-1241
-
-
Xiong, J.1
Onal, M.2
Jilka, R.L.3
Weinstein, R.S.4
Manolagas, S.C.5
O'Brien, C.A.6
-
3
-
-
80053938104
-
Evidence for osteocyte regulation of bone homeostasis through RANKL expression
-
Nakashima T, Hayashi M, Fukunaga T, Kurata K, Oh-Hora M, Feng JQ, et al. Evidence for osteocyte regulation of bone homeostasis through RANKL expression. Nat Med. 2011;17(10):1231-4.
-
(2011)
Nat Med.
, vol.17
, Issue.10
, pp. 1231-1234
-
-
Nakashima, T.1
Hayashi, M.2
Fukunaga, T.3
Kurata, K.4
Oh-Hora, M.5
Feng, J.Q.6
-
4
-
-
12144286871
-
Sclerostin Is an Osteocyte-expressed Negative Regulator of Bone Formation, but Not a Classical BMP Antagonist
-
DOI 10.1084/jem.20031454
-
van Bezooijen RL, Roelen BA, Visser A, van der Wee-Pals L, de Wilt E, Karperien M, et al. Sclerostin is an osteocyteexpressed negative regulator of bone formation, but not a classical BMP antagonist. J Exp Med. 2004;199(6):805-14. (Pubitemid 38375200)
-
(2004)
Journal of Experimental Medicine
, vol.199
, Issue.6
, pp. 805-814
-
-
Van Bezooijen, R.L.1
Roelen, B.A.J.2
Visser, A.3
Van Der Wee-Pals, L.4
De Wilt, E.5
Karperien, M.6
Hamersma, H.7
Papapoulos, S.E.8
Ten Dijke, P.9
Lowik, C.W.G.M.10
-
5
-
-
0033611467
-
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
-
Kong YY, Yoshida H, Sarosi I, Tan HL, Timms E, Capparelli C, et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature. 1999;397(6717):315-23.
-
(1999)
Nature
, vol.397
, Issue.6717
, pp. 315-323
-
-
Kong, Y.Y.1
Yoshida, H.2
Sarosi, I.3
Tan, H.L.4
Timms, E.5
Capparelli, C.6
-
6
-
-
0035282968
-
Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST)
-
Balemans W, Ebeling M, Patel N, Van HE, Olson P, Dioszegi M, et al. Increased bone density in sclerosteosis is due to the deficiency of a novel secreted protein (SOST). Hum Mol Genet. 2001;10(5):537-43. (Pubitemid 32184286)
-
(2001)
Human Molecular Genetics
, vol.10
, Issue.5
, pp. 537-543
-
-
Balemans, W.1
Ebeling, M.2
Patel, N.3
Van Hul, E.4
Olson, P.5
Dioszegi, M.6
Lacza, C.7
Wuyts, W.8
Van Den Ende, J.9
Willems, P.10
Paes-Alves, A.F.11
Hill, S.12
Bueno, M.13
Ramos, F.J.14
Tacconi, P.15
Dikkers, F.G.16
Stratakis, C.17
Lindpaintner, K.18
Vickery, B.19
Foernzler, D.20
Van Hul, W.21
more..
-
7
-
-
0035089781
-
Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein
-
DOI 10.1086/318811
-
Brunkow ME, Gardner JC, Van NJ, Paeper BW, Kovacevich BR, Proll S, et al. Bone dysplasia sclerosteosis results from loss of the SOST gene product, a novel cystine knot-containing protein. Am J Hum Genet. 2001;68(3):577-89. (Pubitemid 32202753)
-
(2001)
American Journal of Human Genetics
, vol.68
, Issue.3
, pp. 577-589
-
-
Brunkow, M.E.1
Gardner, J.C.2
Van Ness, J.3
Paeper, B.W.4
Kovacevich, B.R.5
Proll, S.6
Skonier, J.E.7
Zhao, L.8
Sabo, P.J.9
Fu, Y.-H.10
Alisch, R.S.11
Gillett, L.12
Colbert, T.13
Tacconi, P.14
Galas, D.15
Hamersma, H.16
Beighton, P.17
Mulligan, J.T.18
-
8
-
-
18444400214
-
A 52-kb deletion in the SOST-MEOX1 intergenic region on 17q12-q21 is associated with van Buchem disease in the Dutch population
-
Staehling-Hampton K, Proll S, Paeper BW, Zhao L, Charmley P, Brown A, et al. A 52-kb deletion in the SOST-MEOX1 intergenic region on 17q12-q21 is associated with van Buchem disease in the Dutch population. Am J Med Genet. 2002;110(2):144-52.
-
(2002)
Am J Med Genet.
, vol.110
, Issue.2
, pp. 144-152
-
-
Staehling-Hampton, K.1
Proll, S.2
Paeper, B.W.3
Zhao, L.4
Charmley, P.5
Brown, A.6
-
9
-
-
18244403197
-
Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease
-
Balemans W, Patel N, Ebeling M, Van HE, Wuyts W, Lacza C, et al. Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease. J Med Genet. 2002;39(2):91-7. (Pubitemid 34146376)
-
(2002)
Journal of Medical Genetics
, vol.39
, Issue.2
, pp. 91-97
-
-
Balemans, W.1
Patel, N.2
Ebeling, M.3
Van Hul, E.4
Wuyts, W.5
Lacza, C.6
Dioszegi, M.7
Dikkers, F.G.8
Hildering, P.9
Willems, P.J.10
Verheij, J.B.G.M.11
Lindpaintner, K.12
Vickery, B.13
Foernzler, D.14
Van Hul, W.15
-
10
-
-
27744461726
-
Sclerostin is a delayed secreted product of osteocytes that inhibits bone formation
-
DOI 10.1096/fj.05-4221fje
-
Poole KE, van Bezooijen RL, Loveridge N, Hamersma H, Papapoulos SE, Lowik CW, et al. Sclerostin is a delayed secreted product of osteocytes that inhibits bone formation. FASEB J. 2005;19(13):1842-4. (Pubitemid 41598769)
-
(2005)
FASEB Journal
, vol.19
, Issue.13
, pp. 1842-1844
-
-
Poole, K.E.S.1
Van Bezooijen, R.L.2
Loveridge, N.3
Hamersma, H.4
Papapoulos, S.E.5
Lowik, C.W.6
Reeve, J.7
-
11
-
-
10744221383
-
Osteocyte control of bone formation via sclerostin, a novel BMP antagonist
-
DOI 10.1093/emboj/cdg599
-
Winkler DG, Sutherland MK, Geoghegan JC, Yu C, Hayes T, Skonier JE, et al. Osteocyte control of bone formation via sclerostin, a novel BMP antagonist. EMBO J. 2003;22(23):6267-76. (Pubitemid 37522584)
-
(2003)
EMBO Journal
, vol.22
, Issue.23
, pp. 6267-6276
-
-
Winkler, D.G.1
Sutherland, M.K.2
Geoghegan, J.C.3
Yu, C.4
Hayes, T.5
Skonier, J.E.6
Shpektor, D.7
Jonas, M.8
Kovacevich, B.R.9
Staehling-Hampton, K.10
Appleby, M.11
Brunkow, M.E.12
Latham, J.A.13
-
12
-
-
84861233630
-
Sclerostin deficiency does not induce bone gain in mice lacking osteocyte beta-catenin
-
Chang M, Kramer I, Kneissel M. Sclerostin deficiency does not induce bone gain in mice lacking osteocyte beta-catenin. JBMR. 2011;26:S13.
-
(2011)
JBMR
, vol.26
-
-
Chang, M.1
Kramer, I.2
Kneissel, M.3
-
13
-
-
80053518269
-
Sclerostin stimulates osteocyte support of osteoclast activity by a RANKL-dependent pathway
-
Wijenayaka AR, Kogawa M, Lim HP, Bonewald LF, Findlay DM, Atkins GJ. Sclerostin stimulates osteocyte support of osteoclast activity by a RANKL-dependent pathway. PLoS One. 2011;6(10):e25900.
-
(2011)
PLoS One
, vol.6
, Issue.10
-
-
Wijenayaka, A.R.1
Kogawa, M.2
Lim, H.P.3
Bonewald, L.F.4
Findlay, D.M.5
Atkins, G.J.6
-
14
-
-
67650761071
-
Sclerostin in mineralized matrices and van Buchem disease
-
van Bezooijen RL, Bronckers AL, Gortzak RA, Hogendoorn PC, Wee-Pals L, Balemans W, et al. Sclerostin in mineralized matrices and van Buchem disease. J Dent Res. 2009;88(6):569-74.
-
(2009)
J Dent Res.
, vol.88
, Issue.6
, pp. 569-574
-
-
Van Bezooijen, R.L.1
Bronckers, A.L.2
Gortzak, R.A.3
Hogendoorn, P.C.4
Wee-Pals, L.5
Balemans, W.6
-
15
-
-
44449099165
-
Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength
-
DOI 10.1359/jbmr.080216
-
Li X, Ominsky MS, Niu QT, Sun N, Daugherty B, D'Agostin D, et al. Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength. J Bone Miner Res. 2008;23(6):860-9. (Pubitemid 351768804)
-
(2008)
Journal of Bone and Mineral Research
, vol.23
, Issue.6
, pp. 860-869
-
-
Li, X.1
Ominsky, M.S.2
Niu, Q.-T.3
Sun, N.4
Daugherty, B.5
D'Agostin, D.6
Kurahara, C.7
Gao, Y.8
Cao, J.9
Gong, J.10
Asuncion, F.11
Barrero, M.12
Warmington, K.13
Dwyer, D.14
Stolina, M.15
Morony, S.16
Sarosi, I.17
Kostenuik, P.J.18
Lacey, D.L.19
Simonet, W.S.20
Hua, Z.K.21
Paszty, C.22
more..
-
16
-
-
79952118262
-
Sclerostin: Current knowledge and future perspectives
-
Moester MJ, Papapoulos SE, Lowik CW, van Bezooijen RL. Sclerostin: current knowledge and future perspectives. Calcif Tissue Int. 2010;87(2):99-107.
-
(2010)
Calcif Tissue Int.
, vol.87
, Issue.2
, pp. 99-107
-
-
Moester, M.J.1
Papapoulos, S.E.2
Lowik, C.W.3
Van Bezooijen, R.L.4
-
17
-
-
0041630893
-
The natural history of sclerosteosis
-
DOI 10.1034/j.1399-0004.2003.00036.x
-
Hamersma H, Gardner J, Beighton P. The natural history of sclerosteosis. Clin Genet. 2003;63(3):192-7. (Pubitemid 36949919)
-
(2003)
Clinical Genetics
, vol.63
, Issue.3
, pp. 192-197
-
-
Hamersma, H.1
Gardner, J.2
Beighton, P.3
-
18
-
-
0015038783
-
Hyperostosis corticalis generalisata. Eight new cases
-
Van Buchem FS. Hyperostosis corticalis generalisata. Eight new cases. Acta Med Scand. 1971;189(4):257-67.
-
(1971)
Acta Med Scand.
, vol.189
, Issue.4
, pp. 257-267
-
-
Van Buchem, F.S.1
-
20
-
-
33845927993
-
Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation
-
DOI 10.1359/jbmr.061002
-
van Bezooijen RL, Svensson JP, Eefting D, Visser A, van der Horst G, Karperien M, et al. Wnt but not BMP signaling is involved in the inhibitory action of sclerostin on BMP-stimulated bone formation. J Bone Miner Res. 2007;22(1):19-28. (Pubitemid 46032593)
-
(2007)
Journal of Bone and Mineral Research
, vol.22
, Issue.1
, pp. 19-28
-
-
Van Bezooijen, R.L.1
Svensson, J.P.2
Eefting, D.3
Visser, A.4
Van Der Horst, G.5
Karperien, M.6
Quax, P.H.A.7
Vrieling, H.8
Papapoulos, S.E.9
Ten Dijke, P.10
Lowik, W.G.M.C.11
-
21
-
-
21244480924
-
Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling
-
DOI 10.1074/jbc.M413274200
-
Li X, Zhang Y, Kang H, Liu W, Liu P, Zhang J, et al. Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling. J Biol Chem. 2005;280(20):19883-7. (Pubitemid 41379516)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.20
, pp. 19883-19887
-
-
Li, X.1
Zhang, Y.2
Kang, H.3
Liu, W.4
Liu, P.5
Zhang, J.6
Harris, S.E.7
Wu, D.8
-
22
-
-
22844445934
-
SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor
-
DOI 10.1074/jbc.M504308200
-
Semenov M, Tamai K, He X. SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor. J Biol Chem. 2005;280(29):26770-5. (Pubitemid 41040710)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.29
, pp. 26770-26775
-
-
Semenov, M.1
Tamai, K.2
He, X.3
-
24
-
-
0037030681
-
Kremen proteins are Dickkopf receptors that regulate Wnt/β-catenin signalling
-
DOI 10.1038/nature756
-
Mao B, Wu W, Davidson G, Marhold J, Li M, Mechler BM, et al. Kremen proteins are Dickkopf receptors that regulate Wnt/betacatenin signalling. Nature. 2002;417(6889):664-7. (Pubitemid 34614827)
-
(2002)
Nature
, vol.417
, Issue.6889
, pp. 664-667
-
-
Mao, B.1
Wu, W.2
Davidson, G.3
Marhold, J.4
Li, M.5
Mechler, B.M.6
Dellus, H.7
Hoppe, D.8
Stannek, P.9
Walter, C.10
Glinka, A.11
Niehrs, C.12
-
25
-
-
79957612758
-
Bone overgrowth-associated mutations in the LRP4 gene impair sclerostin facilitator function
-
Leupin O, Piters E, Halleux C, Hu S, Kramer I, Morvan F, et al. Bone overgrowth-associated mutations in the LRP4 gene impair sclerostin facilitator function. J Biol Chem. 2011;286(22):19489-500.
-
(2011)
J Biol Chem.
, vol.286
, Issue.22
, pp. 19489-19500
-
-
Leupin, O.1
Piters, E.2
Halleux, C.3
Hu, S.4
Kramer, I.5
Morvan, F.6
-
27
-
-
78651038254
-
Osteopetrosis with syndactyly; a morphological variant of Albers-Schonberg's disease
-
Truswell AS. Osteopetrosis with syndactyly; a morphological variant of Albers-Schonberg's disease. J Bone Joint Surg Br. 1958;40-B(2):209-18.
-
(1958)
J Bone Joint Surg Br.
, vol.40 B
, Issue.2
, pp. 209-218
-
-
Truswell, A.S.1
-
28
-
-
20444383901
-
A generalized skeletal hyperostosis in two siblings caused by a novel mutation in the SOST gene
-
DOI 10.1016/j.bone.2005.02.019, PII S875632820500058X
-
Balemans W, Cleiren E, Siebers U, Horst J, Van HW. A generalized skeletal hyperostosis in two siblings caused by a novel mutation in the SOST gene. Bone. 2005;36(6):943-7. (Pubitemid 40797994)
-
(2005)
Bone
, vol.36
, Issue.6
, pp. 943-947
-
-
Balemans, W.1
Cleiren, E.2
Siebers, U.3
Horst, J.4
Van Hul, W.5
-
29
-
-
77954135190
-
First missense mutation in the SOST gene causing sclerosteosis by loss of sclerostin function
-
Piters E, Culha C, Moester M, Van BR, Adriaensen D, Mueller T, et al. First missense mutation in the SOST gene causing sclerosteosis by loss of sclerostin function. Hum Mutat. 2010;31(7):E1526-43.
-
(2010)
Hum Mutat.
, vol.31
, Issue.7
-
-
Piters, E.1
Culha, C.2
Moester, M.3
Van, B.R.4
Adriaensen, D.5
Mueller, T.6
-
30
-
-
0017330858
-
Sclerosteosis-an autosomal recessive disorder
-
Beighton P, Davidson J, Durr L, Hamersma H. Sclerosteosis-an autosomal recessive disorder. Clin Genet. 1977;11(1):1-7.
-
(1977)
Clin Genet.
, vol.11
, Issue.1
, pp. 1-7
-
-
Beighton, P.1
Davidson, J.2
Durr, L.3
Hamersma, H.4
-
31
-
-
0001049651
-
An uncommon familial systemic disease of the skeleton: Hyperostosis corticalis generalisata familiaris
-
Van Buchem FS, Hadders HN, Ubbens R. An uncommon familial systemic disease of the skeleton: hyperostosis corticalis generalisata familiaris. Acta Radiol. 1955;44(2):109-20.
-
(1955)
Acta Radiol.
, vol.44
, Issue.2
, pp. 109-120
-
-
Van Buchem, F.S.1
Hadders, H.N.2
Ubbens, R.3
-
32
-
-
22244474640
-
Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease
-
DOI 10.1101/gr.3437105
-
Loots GG, Kneissel M, Keller H, Baptist M, Chang J, Collette NM, et al. Genomic deletion of a long-range bone enhancer misregulates sclerostin in Van Buchem disease. Genome Res. 2005;15(7):928-35. (Pubitemid 40994212)
-
(2005)
Genome Research
, vol.15
, Issue.7
, pp. 928-935
-
-
Loots, G.G.1
Kneissel, M.2
Keller, H.3
Baptist, M.4
Chang, J.5
Collette, N.M.6
Ovcharenko, D.7
Plajzer-Frick, I.8
Rubin, E.M.9
-
33
-
-
70350513065
-
Case 150: Van Buchem disease (hyperostosis corticalis generalisata)
-
Wengenroth M, Vasvari G, Federspil PA, Mair J, Schneider P, Stippich C. Case 150: Van Buchem disease (hyperostosis corticalis generalisata). Radiology. 2009;253(1):272-6.
-
(2009)
Radiology
, vol.253
, Issue.1
, pp. 272-276
-
-
Wengenroth, M.1
Vasvari, G.2
Federspil, P.A.3
Mair, J.4
Schneider, P.5
Stippich, C.6
-
34
-
-
0017258367
-
The clinical features of sclerosteosis. A review of the manifestations in twenty-five affected individuals
-
Beighton P, Durr L, Hamersma H. The clinical features of sclerosteosis. A review of the manifestations in twenty-five affected individuals. Ann Intern Med. 1976;84(4):393-7.
-
(1976)
Ann Intern Med.
, vol.84
, Issue.4
, pp. 393-397
-
-
Beighton, P.1
Durr, L.2
Hamersma, H.3
-
35
-
-
81855180504
-
Patients with sclerosteosis and disease carriers: Human models of the effect of sclerostin on bone turnover
-
van Lierop AH, Hamdy NA, Hamersma H, van Bezooijen RL, Power J, Loveridge N, et al. Patients with sclerosteosis and disease carriers: human models of the effect of sclerostin on bone turnover. J Bone Miner Res. 2011;26(12):2804-11.
-
(2011)
J Bone Miner Res.
, vol.26
, Issue.12
, pp. 2804-2811
-
-
Van Lierop, A.H.1
Hamdy, N.A.2
Hamersma, H.3
Van Bezooijen, R.L.4
Power, J.5
Loveridge, N.6
-
37
-
-
0020696562
-
Sclerosteosis: Neurogenetic and pathophysiologic analysis of an American kinship
-
Stein SA, Witkop C, Hill S, Fallon MD, Viernstein L, Gucer G, et al. Sclerosteosis: neurogenetic and pathophysiologic analysis of an American kinship. Neurology. 1983;33(3):267-77. (Pubitemid 13155755)
-
(1983)
Neurology
, vol.33
, Issue.3
, pp. 267-277
-
-
Stein, S.A.1
Witkop, C.2
Hill, S.3
-
38
-
-
0018959214
-
Sclerosteosis in old age
-
Barnard AH, Hamersma H, Kretzmar JH, Beighton P. Sclerosteosis in old age. S Afr Med J. 1980;58(10):401-3. (Pubitemid 10003628)
-
(1980)
South African Medical Journal
, vol.58
, Issue.10
, pp. 401-403
-
-
Barnard, A.H.1
Hamersma, H.2
Kretzmar, J.H.3
Beighton, P.4
-
39
-
-
0021289072
-
The syndrome status of sclerosteosis and van Buchem disease
-
Beighton P, Barnard A, Hamersma H, van der Wouden A. The syndromic status of sclerosteosis and van Buchem disease. Clin Genet. 1984;25(2):175-81. (Pubitemid 14187397)
-
(1984)
Clinical Genetics
, vol.25
, Issue.2
, pp. 175-181
-
-
Beighton, P.1
Barnard, A.2
Hamersma, H.3
Van Der Wouden, A.4
-
40
-
-
17344370229
-
Van Buchem disease (Hyperostosis corticalis generalisata) maps to chromosome 17q12-q21
-
DOI 10.1086/301721
-
Van HW, Balemans W, Van HE, Dikkers FG, Obee H, Stokroos RJ, et al. Van Buchem disease (hyperostosis corticalis generalisata) maps to chromosome 17q12-q21. Am J Hum Genet. 1998;62(2):391-9. (Pubitemid 28110782)
-
(1998)
American Journal of Human Genetics
, vol.62
, Issue.2
, pp. 391-399
-
-
Van Hul, W.1
Balemans, W.2
Van Hul, E.3
Dikkers, F.G.4
Obee, H.5
Stokroos, R.J.6
Hildering, P.7
Vanhoenacker, F.8
Van Camp, G.9
Willems, P.J.10
-
41
-
-
0346243550
-
Van Buchem disease: Lifetime evolution of radioclinical features
-
DOI 10.1007/s00256-003-0675-4
-
Vanhoenacker FM, Balemans W, Tan GJ, Dikkers FG, De Schepper AM, Mathysen DG, et al. Van Buchem disease: lifetime evolution of radioclinical features. Skeletal Radiol. 2003;32(12):708-18. (Pubitemid 37527086)
-
(2003)
Skeletal Radiology
, vol.32
, Issue.12
, pp. 708-718
-
-
Vanhoenacker, F.M.1
Balemans, W.2
Tan, G.J.3
Dikkers, F.D.4
De Schepper, A.M.5
Mathysen, D.G.P.6
Bernaerts, A.7
Van Hul, W.8
-
43
-
-
9144265626
-
Patients with Van Buchem Disease, an Osteosclerotic Genetic Disease, Have Elevated Bone Formation Markers, Higher Bone Density, and Greater Derived Polar Moment of Inertia than Normal
-
DOI 10.1210/jc.2003-030201
-
Wergedal JE, Veskovic K, Hellan M, Nyght C, Balemans W, Libanati C, et al. Patients with Van Buchem disease, an osteosclerotic genetic disease, have elevated bone formation markers, higher bone density, and greater derived polar moment of inertia than normal. J Clin Endocrinol Metab. 2003;88(12):5778-83. (Pubitemid 38033050)
-
(2003)
Journal of Clinical Endocrinology and Metabolism
, vol.88
, Issue.12
, pp. 5778-5783
-
-
Wergedal, J.E.1
Veskovic, K.2
Hellan, M.3
Nyght, C.4
Balemans, W.5
Libanati, C.6
Vanhoenacker, F.M.7
Tan, J.8
Baylink, D.J.9
Van Hul, W.10
-
45
-
-
0022545440
-
Cranial CT findings in sclerosteosis
-
Hill SC, Stein SA, Dwyer A, Altman J, Dorwart R, Doppman J. Cranial CT findings in sclerosteosis. AJNR Am J Neuroradiol. 1986;7(3):505-11. (Pubitemid 16083439)
-
(1986)
American Journal of Neuroradiology
, vol.7
, Issue.3
, pp. 505-511
-
-
Hill, S.C.1
Stein, S.A.2
Dwyer, A.3
-
46
-
-
0027469826
-
Sclerosteosis: Neurosurgical experience with 14 cases
-
du Plessis JJ. Sclerosteosis: neurosurgical experience with 14 cases. J Neurosurg. 1993;78(3):388-92. (Pubitemid 23073207)
-
(1993)
Journal of Neurosurgery
, vol.78
, Issue.3
, pp. 388-392
-
-
Du Plessis, J.J.1
-
47
-
-
78650955673
-
Regulation of circulating sclerostin levels by sex steroids in women and in men
-
Modder UI, Clowes JA, Hoey K, Peterson JM, McCready L, Oursler MJ, et al. Regulation of circulating sclerostin levels by sex steroids in women and in men. J Bone Miner Res. 2011;26(1):27-34.
-
(2011)
J Bone Miner Res.
, vol.26
, Issue.1
, pp. 27-34
-
-
Modder, U.I.1
Clowes, J.A.2
Hoey, K.3
Peterson, J.M.4
McCready, L.5
Oursler, M.J.6
-
48
-
-
77957846460
-
Relation of age, gender, and bone mass to circulating sclerostin levels in women and men
-
Modder UI, Hoey KA, Amin S, McCready LK, Achenbach SJ, Riggs BL, et al. Relation of age, gender, and bone mass to circulating sclerostin levels in women and men. J Bone Miner Res. 2011;26(2):373-9.
-
(2011)
J Bone Miner Res.
, vol.26
, Issue.2
, pp. 373-379
-
-
Modder, U.I.1
Hoey, K.A.2
Amin, S.3
McCready, L.K.4
Achenbach, S.J.5
Riggs, B.L.6
-
49
-
-
84861228834
-
Sclerostin levels during growth in children
-
epub
-
Kirmani S, Amin S, McCready LK, Atkinson EJ, Melton LJ, III, Muller R, et al. Sclerostin levels during growth in children. Osteoporos Int. (2011) (epub).
-
(2011)
Osteoporos Int
-
-
Kirmani, S.1
Amin, S.2
McCready, L.K.3
Atkinson, E.J.4
Melton III, L.J.5
Muller, R.6
-
50
-
-
59649096700
-
NMR structure of the Wnt modulator protein Sclerostin
-
Weidauer SE, Schmieder P, Beerbaum M, Schmitz W, Oschkinat H, Mueller TD. NMR structure of the Wnt modulator protein Sclerostin. Biochem Biophys Res Commun. 2009;380(1):160-5.
-
(2009)
Biochem Biophys Res Commun.
, vol.380
, Issue.1
, pp. 160-165
-
-
Weidauer, S.E.1
Schmieder, P.2
Beerbaum, M.3
Schmitz, W.4
Oschkinat, H.5
Mueller, T.D.6
-
51
-
-
67449092566
-
Characterization of the structural features and interactions of sclerostin: Molecular insight into a key regulator of Wnt-mediated bone formation
-
Veverka V, Henry AJ, Slocombe PM, Ventom A, Mulloy B, Muskett FW, et al. Characterization of the structural features and interactions of sclerostin: molecular insight into a key regulator of Wnt-mediated bone formation. J Biol Chem. 2009;284(16):10890-900.
-
(2009)
J Biol Chem.
, vol.284
, Issue.16
, pp. 10890-10900
-
-
Veverka, V.1
Henry, A.J.2
Slocombe, P.M.3
Ventom, A.4
Mulloy, B.5
Muskett, F.W.6
-
52
-
-
79960086652
-
Determination of serum and plasma sclerostin concentrations by enzymelinked immunoassays
-
McNulty M, Singh RJ, Li X, Bergstralh EJ, Kumar R. Determination of serum and plasma sclerostin concentrations by enzymelinked immunoassays. J Clin Endocrinol Metab. 2011;96(7):E1159-62.
-
(2011)
J Clin Endocrinol Metab.
, vol.96
, Issue.7
-
-
McNulty, M.1
Singh, R.J.2
Li, X.3
Bergstralh, E.J.4
Kumar, R.5
-
53
-
-
41949089764
-
Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin
-
Robling AG, Niziolek PJ, Baldridge LA, Condon KW, Allen MR, Alam I, et al. Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin. J Biol Chem. 2008;283(9):5866-75.
-
(2008)
J Biol Chem.
, vol.283
, Issue.9
, pp. 5866-5875
-
-
Robling, A.G.1
Niziolek, P.J.2
Baldridge, L.A.3
Condon, K.W.4
Allen, M.R.5
Alam, I.6
-
54
-
-
70349934212
-
Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt/beta-catenin signaling
-
Lin C, Jiang X, Dai Z, Guo X, Weng T, Wang J, et al. Sclerostin mediates bone response to mechanical unloading through antagonizing Wnt/beta-catenin signaling. J Bone Miner Res. 2009;24(10):1651-61.
-
(2009)
J Bone Miner Res.
, vol.24
, Issue.10
, pp. 1651-1661
-
-
Lin, C.1
Jiang, X.2
Dai, Z.3
Guo, X.4
Weng, T.5
Wang, J.6
-
55
-
-
77952771209
-
Increased sclerostin serum levels associated with bone formation and resorption markers in patients with immobilization-induced bone loss
-
Gaudio A, Pennisi P, Bratengeier C, Torrisi V, Lindner B, Mangiafico RA, et al. Increased sclerostin serum levels associated with bone formation and resorption markers in patients with immobilization-induced bone loss. J Clin Endocrinol Metab. 2010;95(5):2248-53.
-
(2010)
J Clin Endocrinol Metab.
, vol.95
, Issue.5
, pp. 2248-2253
-
-
Gaudio, A.1
Pennisi, P.2
Bratengeier, C.3
Torrisi, V.4
Lindner, B.5
Mangiafico, R.A.6
-
56
-
-
84861227639
-
Association between sclerostin and bone density in chronic SCI
-
epub
-
Morse LR, Sudhakar S, Danilack V, Tun C, Lazzari A, Gagnon DR, et al. Association between sclerostin and bone density in chronic SCI. J Bone Miner Res. (2011) (epub).
-
(2011)
J Bone Miner Res
-
-
Morse, L.R.1
Sudhakar, S.2
Danilack, V.3
Tun, C.4
Lazzari, A.5
Gagnon, D.R.6
-
57
-
-
26844521277
-
Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: A novel mechanism for hormonal control of osteoblastogenesis
-
DOI 10.1210/en.2005-0239
-
Bellido T, Ali AA, Gubrij I, Plotkin LI, Fu Q, O'Brien CA, et al. Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis. Endocrinology. 2005;146(11):4577-83. (Pubitemid 41446595)
-
(2005)
Endocrinology
, vol.146
, Issue.11
, pp. 4577-4583
-
-
Bellido, T.1
Ali, A.A.2
Gubrij, I.3
Plotkin, L.I.4
Fu, Q.5
O'Brien, C.A.6
Manolagas, S.C.7
Jilka, R.L.8
-
58
-
-
34547109349
-
Effects of intermittent parathyroid hormone (PTH) administration on SOST mRNA and protein in rat bone
-
DOI 10.1007/s10735-007-9096-3
-
Silvestrini G, Ballanti P, Leopizzi M, Sebastiani M, Berni S, Di VM, et al. Effects of intermittent parathyroid hormone (PTH) administration on SOST mRNA and protein in rat bone. J Mol Histol. 2007;38(4):261-9. (Pubitemid 47106897)
-
(2007)
Journal of Molecular Histology
, vol.38
, Issue.4
, pp. 261-269
-
-
Silvestrini, G.1
Ballanti, P.2
Leopizzi, M.3
Sebastiani, M.4
Berni, S.5
Di Vito, M.6
Bonucci, E.7
-
59
-
-
77957838571
-
Patients with primary hyperparathyroidism have lower circulating sclerostin levels than euparathyroid controls
-
van Lierop AH, Witteveen JE, Hamdy NA, Papapoulos SE. Patients with primary hyperparathyroidism have lower circulating sclerostin levels than euparathyroid controls. Eur J Endocrinol. 2010;163(5):833-7.
-
(2010)
Eur J Endocrinol.
, vol.163
, Issue.5
, pp. 833-837
-
-
Van Lierop, A.H.1
Witteveen, J.E.2
Hamdy, N.A.3
Papapoulos, S.E.4
-
60
-
-
77957853500
-
Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women
-
Drake MT, Srinivasan B, Modder UI, Peterson JM, McCready LK, Riggs BL, et al. Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women. J Clin Endocrinol Metab. 2010;95(11):5056-62.
-
(2010)
J Clin Endocrinol Metab.
, vol.95
, Issue.11
, pp. 5056-5062
-
-
Drake, M.T.1
Srinivasan, B.2
Modder, U.I.3
Peterson, J.M.4
McCready, L.K.5
Riggs, B.L.6
-
61
-
-
68949163965
-
Pro-inflammatory cytokines TNF-related weak inducer of apoptosis (TWEAK) and TNFalpha induce the mitogenactivated protein kinase (MAPK)-dependent expression of sclerostin in human osteoblasts
-
Vincent C, Findlay DM, Welldon KJ, Wijenayaka AR, Zheng TS, Haynes DR, et al. Pro-inflammatory cytokines TNF-related weak inducer of apoptosis (TWEAK) and TNFalpha induce the mitogenactivated protein kinase (MAPK)-dependent expression of sclerostin in human osteoblasts. J Bone Miner Res. 2009;24(8):1434-49.
-
(2009)
J Bone Miner Res.
, vol.24
, Issue.8
, pp. 1434-1449
-
-
Vincent, C.1
Findlay, D.M.2
Welldon, K.J.3
Wijenayaka, A.R.4
Zheng, T.S.5
Haynes, D.R.6
-
62
-
-
70350558488
-
Altered skeletal expression of sclerostin and its link to radiographic progression in ankylosing spondylitis
-
Appel H, Ruiz-Heiland G, Listing J, Zwerina J, Herrmann M, Mueller R, et al. Altered skeletal expression of sclerostin and its link to radiographic progression in ankylosing spondylitis. Arthr Rheum. 2009;60(11):3257-62.
-
(2009)
Arthr Rheum.
, vol.60
, Issue.11
, pp. 3257-3262
-
-
Appel, H.1
Ruiz-Heiland, G.2
Listing, J.3
Zwerina, J.4
Herrmann, M.5
Mueller, R.6
-
63
-
-
77954798515
-
Thiazolidinediones induce osteocyte apoptosis and increase sclerostin expression
-
Mabilleau G, Mieczkowska A, Edmonds ME. Thiazolidinediones induce osteocyte apoptosis and increase sclerostin expression. Diabet Med. 2010;27(8):925-32.
-
(2010)
Diabet Med.
, vol.27
, Issue.8
, pp. 925-932
-
-
Mabilleau, G.1
Mieczkowska, A.2
Edmonds, M.E.3
-
64
-
-
45349088375
-
Glucocorticoid excess in mice results in early activation of osteoclastogenesis and adipogenesis and prolonged suppression of osteogenesis: A longitudinal study of gene expression in bone tissue from glucocorticoid- treated mice
-
DOI 10.1002/art.23454
-
Yao W, Cheng Z, Busse C, Pham A, Nakamura MC, Lane NE. Glucocorticoid excess in mice results in early activation of osteoclastogenesis and adipogenesis and prolonged suppression of osteogenesis: a longitudinal study of gene expression in bone tissue from glucocorticoid-treated mice. Arthr Rheum. 2008;58(6):1674-86. (Pubitemid 351847520)
-
(2008)
Arthritis and Rheumatism
, vol.58
, Issue.6
, pp. 1674-1686
-
-
Yao, W.1
Cheng, Z.2
Busse, C.3
Pham, A.4
Nakamura, M.C.5
Lane, N.E.6
-
65
-
-
28744432803
-
Bone mineral density in sclerosteosis; affected individuals and gene carriers
-
DOI 10.1210/jc.2005-1235
-
Gardner JC, van Bezooijen RL, Mervis B, Hamdy NA, Lowik CW, Hamersma H, et al. Bone mineral density in sclerosteosis; affected individuals and gene carriers. J Clin Endocrinol Metab. 2005;90(12):6392-5. (Pubitemid 41759290)
-
(2005)
Journal of Clinical Endocrinology and Metabolism
, vol.90
, Issue.12
, pp. 6392-6395
-
-
Gardner, J.C.1
Van Bezooijen, R.L.2
Mervis, B.3
Hamdy, N.A.T.4
Lowik, C.W.G.M.5
Hamersma, H.6
Beighton, P.7
Papapoulos, S.E.8
-
66
-
-
65549152230
-
Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis
-
Li X, Ominsky MS, Warmington KS, Morony S, Gong J, Cao J, et al. Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis. J Bone Miner Res. 2009;24(4):578-88.
-
(2009)
J Bone Miner Res.
, vol.24
, Issue.4
, pp. 578-588
-
-
Li, X.1
Ominsky, M.S.2
Warmington, K.S.3
Morony, S.4
Gong, J.5
Cao, J.6
-
67
-
-
77953481395
-
Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength
-
Ominsky MS, Vlasseros F, Jolette J, Smith SY, Stouch B, Doellgast G, et al. Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength. J Bone Miner Res. 2010;25(5):948-59.
-
(2010)
J Bone Miner Res.
, vol.25
, Issue.5
, pp. 948-959
-
-
Ominsky, M.S.1
Vlasseros, F.2
Jolette, J.3
Smith, S.Y.4
Stouch, B.5
Doellgast, G.6
-
68
-
-
78650958526
-
Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody
-
Padhi D, Jang G, Stouch B, Fang L, Posvar E. Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody. J Bone Miner Res. 2011;26(1):19-26.
-
(2011)
J Bone Miner Res.
, vol.26
, Issue.1
, pp. 19-26
-
-
Padhi, D.1
Jang, G.2
Stouch, B.3
Fang, L.4
Posvar, E.5
-
69
-
-
79961118892
-
Sclerostin antibody treatment enhances bone strength but does not prevent growth retardation in young mice treated with dexamethasone
-
Marenzana M, Greenslade K, Eddleston A, Okoye R, Marshall D, Moore A, et al. Sclerostin antibody treatment enhances bone strength but does not prevent growth retardation in young mice treated with dexamethasone. Arthr Rheum. 2011;63(8):2385-95.
-
(2011)
Arthr Rheum.
, vol.63
, Issue.8
, pp. 2385-2395
-
-
Marenzana, M.1
Greenslade, K.2
Eddleston, A.3
Okoye, R.4
Marshall, D.5
Moore, A.6
-
70
-
-
70349920691
-
A short treatment with an antibody to sclerostin can inhibit bone loss in an ongoing model of colitis
-
Eddleston A, Marenzana M, Moore AR, Stephens P, Muzylak M, Marshall D, et al. A short treatment with an antibody to sclerostin can inhibit bone loss in an ongoing model of colitis. J Bone Miner Res. 2009;24(10):1662-71.
-
(2009)
J Bone Miner Res.
, vol.24
, Issue.10
, pp. 1662-1671
-
-
Eddleston, A.1
Marenzana, M.2
Moore, A.R.3
Stephens, P.4
Muzylak, M.5
Marshall, D.6
-
71
-
-
79955635177
-
Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bones
-
Ominsky MS, Li C, Li X, Tan HL, Lee E, Barrero M, et al. Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bones. J Bone Miner Res. 2011;26(5):1012-21.
-
(2011)
J Bone Miner Res.
, vol.26
, Issue.5
, pp. 1012-1021
-
-
Ominsky, M.S.1
Li, C.2
Li, X.3
Tan, H.L.4
Lee, E.5
Barrero, M.6
|