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Volumn 63, Issue 8, 2011, Pages 2385-2395

Sclerostin antibody treatment enhances bone strength but does not prevent growth retardation in young mice treated with dexamethasone

Author keywords

[No Author keywords available]

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ACID PHOSPHATASE TARTRATE RESISTANT PHOSPHATASE 5B; AMINO TERMINAL TELOPEPTIDE; DEXAMETHASONE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY SCL ABI; OSTEOCALCIN; UNCLASSIFIED DRUG;

EID: 79961118892     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.30385     Document Type: Article
Times cited : (64)

References (39)
  • 2
    • 34548554688 scopus 로고    scopus 로고
    • Glucocorticoid-induced osteoporosis: Pathophysiology and therapy
    • DOI 10.1007/s00198-007-0394-0
    • Canalis E, Mazziotti G, Giustina A, Bilezikian JP,. Glucocorticoid- induced osteoporosis: pathophysiology and therapy. Osteoporos Int 2007; 18: 1319-28. (Pubitemid 47389469)
    • (2007) Osteoporosis International , vol.18 , Issue.10 , pp. 1319-1328
    • Canalis, E.1    Mazziotti, G.2    Giustina, A.3    Bilezikian, J.P.4
  • 3
    • 0035205516 scopus 로고    scopus 로고
    • Molecular mechanisms of glucocorticoid-induced osteoporosis
    • DOI 10.1016/S8756-3282(01)00610-X, PII S875632820100610X
    • Patschan D, Loddenkemper K, Buttgereit F,. Molecular mechanisms of glucocorticoid-induced osteoporosis. Bone 2001; 29: 498-505. (Pubitemid 33124290)
    • (2001) Bone , vol.29 , Issue.6 , pp. 498-505
    • Patschan, D.1    Loddenkemper, K.2    Buttgereit, F.3
  • 4
    • 33644549962 scopus 로고    scopus 로고
    • Glucocorticoid-treated mice have localized changes in trabecular bone material properties and osteocyte lacunas size that are not observed in placebo-treated or estrogen-deficient mice
    • et al.
    • Lane NE, Yao W, Balooch M, Nalla RK, Balooch G, Habelitz S, et al. Glucocorticoid-treated mice have localized changes in trabecular bone material properties and osteocyte lacunas size that are not observed in placebo-treated or estrogen-deficient mice. J Bone Miner Res 2006; 21: 466-76.
    • (2006) J Bone Miner Res , vol.21 , pp. 466-476
    • Lane, N.E.1    Yao, W.2    Balooch, M.3    Nalla, R.K.4    Balooch, G.5    Habelitz, S.6
  • 5
    • 84959745128 scopus 로고
    • Glucocorticoid effects on statural growth
    • Avioli LV,. Glucocorticoid effects on statural growth. Br J Rheumatol 1993; 32 Suppl 2: 27-30. (Pubitemid 23179592)
    • (1993) British Journal of Rheumatology , vol.32 , Issue.SUPPL. 2 , pp. 27-30
    • Avioli, L.V.1
  • 7
    • 0026460126 scopus 로고
    • Interactions between growth hormone and dexamethasone in skeletal growth and bone structure of the young mouse
    • Atman A, Hochberg Z, Silbermann M,. Interactions between growth hormone and dexamethasone in skeletal growth and bone structure of the young mouse. Calcif Tissue Int 1992; 51: 298-304.
    • (1992) Calcif Tissue Int , vol.51 , pp. 298-304
    • Atman, A.1    Hochberg, Z.2    Silbermann, M.3
  • 8
    • 0346057833 scopus 로고    scopus 로고
    • Systemic and Local Regulation of the Growth Plate
    • DOI 10.1210/er.2002-0033
    • Van der Eerden BC, Karperien M, Wit JM,. Systemic and local regulation of the growth plate. Endocr Rev 2003; 24: 782-801. (Pubitemid 38067699)
    • (2003) Endocrine Reviews , vol.24 , Issue.6 , pp. 782-801
    • Van Der Eerden, B.C.J.1    Karperien, M.2    Wit, J.M.3
  • 9
    • 0033990306 scopus 로고    scopus 로고
    • Evaluation of apoptosis and the glucocorticoid receptor in the cartilage growth plate and metaphyseal bone cells of rats after high-dose treatment with corticosterone
    • et al.
    • Silvestrini G, Ballanti P, Patacchioli FR, Mocetti P, Di Grezia R, Wedard BM, et al. Evaluation of apoptosis and the glucocorticoid receptor in the cartilage growth plate and metaphyseal bone cells of rats after high-dose treatment with corticosterone. Bone 2000; 26: 33-42.
    • (2000) Bone , vol.26 , pp. 33-42
    • Silvestrini, G.1    Ballanti, P.2    Patacchioli, F.R.3    Mocetti, P.4    Di Grezia, R.5    Wedard, B.M.6
  • 10
    • 0037354059 scopus 로고    scopus 로고
    • Growth retardation induced by dexamethasone is associated with increased apoptosis of the growth plate chondrocytes
    • DOI 10.1677/joe.0.1760331
    • Chrysis D, Ritzen EM, Savendahl L,. Growth retardation induced by dexamethasone is associated with increased apoptosis of the growth plate chondrocytes. J Endocrinol 2003; 176: 331-7. (Pubitemid 36410417)
    • (2003) Journal of Endocrinology , vol.176 , Issue.3 , pp. 331-337
    • Chrysis, D.1    Ritzen, E.M.2    Savendahl, L.3
  • 11
    • 0038716012 scopus 로고    scopus 로고
    • Short-term glucocorticoid treatment of prepubertal mice decreases growth and IGF-I expression in the growth plate
    • DOI 10.1677/joe.0.1770381
    • Smink JJ, Gresnigt MG, Hamers N, Koedam JA, Berger R, Van Buul-Offers SC,. Short-term glucocorticoid treatment of prepubertal mice decreases growth and IGF-I expression in the growth plate. J Endocrinol 2003; 177: 381-8. (Pubitemid 36722293)
    • (2003) Journal of Endocrinology , vol.177 , Issue.3 , pp. 381-388
    • Smink, J.J.1    Gresnigt, M.G.2    Hamers, N.3    Koedam, J.A.4    Berger, R.5    Van Buul-Offers, S.C.6
  • 12
    • 0037195522 scopus 로고    scopus 로고
    • Glucocorticoids inhibit vascular endothelial growth factor expression in growth plate chondrocytes
    • DOI 10.1016/S0303-7207(02)00276-9, PII S0303720702002769
    • Koedam JA, Smink JJ, van Buul-Offers SC,. Glucocorticoids inhibit vascular endothelial growth factor expression in growth plate chondrocytes. Mol Cell Endocrinol 2002; 29; 197: 35-44. (Pubitemid 35304775)
    • (2002) Molecular and Cellular Endocrinology , vol.197 , Issue.1-2 , pp. 35-44
    • Koedam, J.A.1    Smink, J.J.2    Van Buul-Offers, S.C.3
  • 13
    • 77956863339 scopus 로고    scopus 로고
    • Sclerostin: A gem from the genome leads to bone-building antibodies
    • Paszty C, Turner CH, Robinson MK,. Sclerostin: a gem from the genome leads to bone-building antibodies. J Bone Miner Res 2010; 25: 1897-904.
    • (2010) J Bone Miner Res , vol.25 , pp. 1897-1904
    • Paszty, C.1    Turner, C.H.2    Robinson, M.K.3
  • 16
    • 0023970128 scopus 로고
    • Sclerosteosis
    • Beighton P,. Sclerosteosis. J Med Genet 1988; 25: 200-3.
    • (1988) J Med Genet , vol.25 , pp. 200-203
    • Beighton, P.1
  • 19
    • 70349920691 scopus 로고    scopus 로고
    • A short treatment with an antibody to sclerostin can inhibit bone loss in an ongoing model of colitis
    • et al.
    • Eddleston A, Marenzana M, Moore AR, Stephens P, Muzylak M, Marshall D, et al. A short treatment with an antibody to sclerostin can inhibit bone loss in an ongoing model of colitis. J Bone Miner Res 2009; 24: 1662-71.
    • (2009) J Bone Miner Res , vol.24 , pp. 1662-1671
    • Eddleston, A.1    Marenzana, M.2    Moore, A.R.3    Stephens, P.4    Muzylak, M.5    Marshall, D.6
  • 20
    • 65549152230 scopus 로고    scopus 로고
    • Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis
    • et al.
    • Li X, Ominsky MS, Warmington KS, Morony S, Gong J, Cao J, et al. Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis. J Bone Miner Res 2009; 24: 578-88.
    • (2009) J Bone Miner Res , vol.24 , pp. 578-588
    • Li, X.1    Ominsky, M.S.2    Warmington, K.S.3    Morony, S.4    Gong, J.5    Cao, J.6
  • 21
    • 77953481395 scopus 로고    scopus 로고
    • Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength
    • et al.
    • Ominsky M, Vlasseros F, Jolette J, Smith S, Stouch B, Doellgast G, et al. Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength. J Bone Miner Res 2010; 25: 948-59.
    • (2010) J Bone Miner Res , vol.25 , pp. 948-959
    • Ominsky, M.1    Vlasseros, F.2    Jolette, J.3    Smith, S.4    Stouch, B.5    Doellgast, G.6
  • 22
    • 77956822573 scopus 로고    scopus 로고
    • Sclerostin antibody treatment enhances metaphyseal bone healing in rats
    • Agholme F, Li X, Isaksson H, Ke HZ, Aspenberg P,. Sclerostin antibody treatment enhances metaphyseal bone healing in rats. J Bone Miner Res 2010; 25: 2412-8.
    • (2010) J Bone Miner Res , vol.25 , pp. 2412-2418
    • Agholme, F.1    Li, X.2    Isaksson, H.3    Ke, H.Z.4    Aspenberg, P.5
  • 23
    • 78650958526 scopus 로고    scopus 로고
    • Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody
    • Padhi D, Jang G, Stouch B, Fang L, Posvar E,. Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody. J Bone Miner Res 2011; 26: 19-26.
    • (2011) J Bone Miner Res , vol.26 , pp. 19-26
    • Padhi, D.1    Jang, G.2    Stouch, B.3    Fang, L.4    Posvar, E.5
  • 26
    • 0027175806 scopus 로고
    • Basic biomechanical measurements of bone: A tutorial
    • Turner CH, Burr DB,. Basic biomechanical measurements of bone: a tutorial. Bone 1993; 14: 595-606.
    • (1993) Bone , vol.14 , pp. 595-606
    • Turner, C.H.1    Burr, D.B.2
  • 28
    • 55849147355 scopus 로고    scopus 로고
    • Glucocorticoid-induced bone loss in mice can be reversed by the actions of parathyroid hormone and risedronate on different pathways for bone formation and mineralization
    • et al.
    • Yao W, Cheng Z, Pham A, Busse C, Zimmermann EA, Ritchie RO, et al. Glucocorticoid-induced bone loss in mice can be reversed by the actions of parathyroid hormone and risedronate on different pathways for bone formation and mineralization. Arthritis Rheum 2008; 58: 3485-97.
    • (2008) Arthritis Rheum , vol.58 , pp. 3485-3497
    • Yao, W.1    Cheng, Z.2    Pham, A.3    Busse, C.4    Zimmermann, E.A.5    Ritchie, R.O.6
  • 29
    • 58149492521 scopus 로고    scopus 로고
    • BMP/Wnt antagonists are upregulated by dexamethasone in osteoblasts and reversed by alendronate and PTH: Potential therapeutic targets for glucocorticoid-induced osteoporosis
    • et al.
    • Hayashi K, Yamaguchi T, Yano S, Kanazawa I, Yamauchi M, Yamamoto M, et al. BMP/Wnt antagonists are upregulated by dexamethasone in osteoblasts and reversed by alendronate and PTH: potential therapeutic targets for glucocorticoid-induced osteoporosis. Biochem Biophys Res Commun 2009; 379: 261-6.
    • (2009) Biochem Biophys Res Commun , vol.379 , pp. 261-266
    • Hayashi, K.1    Yamaguchi, T.2    Yano, S.3    Kanazawa, I.4    Yamauchi, M.5    Yamamoto, M.6
  • 30
    • 17744364306 scopus 로고    scopus 로고
    • Secreted frizzled-related protein 1 modulates glucocorticoid attenuation of osteogenic activities and bone mass
    • DOI 10.1210/en.2004-1050
    • Wang FS, Lin CL, Chen YJ, Wang CJ, Yang KD, Huang YT, et al. Secreted frizzled-related protein 1 modulates glucocorticoid attenuation of osteogenic activities and bone mass. Endocrinology 2005; 146: 2415-23. (Pubitemid 40577529)
    • (2005) Endocrinology , vol.146 , Issue.5 , pp. 2415-2423
    • Wang, F.-S.1    Lin, C.-L.2    Chen, Y.-J.3    Wang, C.-J.4    Yang, K.D.5    Huang, Y.-T.6    Sun, Y.-C.7    Huang, H.-C.8
  • 31
    • 41549138806 scopus 로고    scopus 로고
    • Modulation of Dickkopf-1 attenuates glucocorticoid induction of osteoblast apoptosis, adipocytic differentiation, and bone mass loss
    • Wang FS, Ko JY, Yeh DW, Ke HC, Wu HL,. Modulation of Dickkopf-1 attenuates glucocorticoid induction of osteoblast apoptosis, adipocytic differentiation, and bone mass loss. Endocrinology 2008; 149: 1793-801.
    • (2008) Endocrinology , vol.149 , pp. 1793-1801
    • Wang, F.S.1    Ko, J.Y.2    Yeh, D.W.3    Ke, H.C.4    Wu, H.L.5
  • 32
    • 26844521277 scopus 로고    scopus 로고
    • Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: A novel mechanism for hormonal control of osteoblastogenesis
    • DOI 10.1210/en.2005-0239
    • Bellido T, Ali AA, Gubrij I, Plotkin LI, Fu Q, O'Brien CA, et al. Chronic elevation of parathyroid hormone in mice reduces expression of sclerostin by osteocytes: a novel mechanism for hormonal control of osteoblastogenesis. Endocrinology 2005; 146: 4577-83. (Pubitemid 41446595)
    • (2005) Endocrinology , vol.146 , Issue.11 , pp. 4577-4583
    • Bellido, T.1    Ali, A.A.2    Gubrij, I.3    Plotkin, L.I.4    Fu, Q.5    O'Brien, C.A.6    Manolagas, S.C.7    Jilka, R.L.8
  • 35
    • 14644396168 scopus 로고    scopus 로고
    • Thyroid hormone, but not parathyroid hormone, partially restores glucocorticoid-induced growth retardation
    • DOI 10.1007/s00467-004-1690-y, IPNA Seventh Symposium on Growth and Development in Children with Chronic Kidney Disease: The Molecular Basis of Skeletal
    • Van Buul-Offers SC, Smink JJ, Gresnigt R, Hamers N, Koedam J, Karperien M,. Thyroid hormone, but not parathyroid hormone, partially restores glucocorticoid-induced growth retardation. Pediatr Nephrol 2005; 20: 335-41. (Pubitemid 40309939)
    • (2005) Pediatric Nephrology , vol.20 , Issue.3 SPEC. ISS. , pp. 335-341
    • Van Buul-Offers, S.C.1    Smink, J.J.2    Gresnigt, R.3    Hamers, N.4    Koedam, J.5    Karperien, M.6
  • 36
    • 33744917514 scopus 로고    scopus 로고
    • The anabolic effect of PTH on bone is attenuated by simultaneous glucocorticoid treatment
    • DOI 10.1016/j.bone.2006.01.142, PII S8756328206001931
    • Oxlund H, Ortoft G, Thomsen JS, Danielsen CC, Ejersted C, Andreassen TT,. The anabolic effect of PTH on bone is attenuated by simultaneous glucocorticoid treatment. Bone 2006; 39: 244-52. (Pubitemid 43851361)
    • (2006) Bone , vol.39 , Issue.2 , pp. 244-252
    • Oxlund, H.1    Ortoft, G.2    Thomsen, J.S.3    Danielsen, C.C.4    Ejersted, C.5    Andreassen, T.T.6
  • 37
    • 14944356482 scopus 로고    scopus 로고
    • Glucocorticoids inhibit osteocalcin transcription in osteoblasts by suppressing Egr2/Krox20-binding enhancer
    • DOI 10.1002/art.20872
    • Leclerc N, Noh T, Khokhar A, Smith E, Frenkel B,. Glucocorticoids inhibit osteocalcin transcription in osteoblasts by suppressing Egr2/Krox20-binding enhancer. Arthritis Rheum 2005; 52: 929-39. (Pubitemid 40365117)
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.3 , pp. 929-939
    • Leclerc, N.1    Noh, T.2    Khokhar, A.3    Smith, E.4    Frenkel, B.5


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