GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity

Journal of Biological Chemistry

Volumn 287, Issue 21, 2012, Pages 17176-17185

  Luo, Ruibai ^a   Akpan, Itoro O ^a   Hayashi, Ryo ^b   Sramko, Marek ^a   Barr, Valarie ^a   Shiba, Yoko ^a   Randazzo, Paul A ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAGA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

C TERMINUS; C-TERMINAL PEPTIDES; CLATHRINS; CO-IMMUNOPRECIPITATIONS; GLIOBLASTOMAS; GOLGI MEMBRANE; GTP BINDING; GTPASE-ACTIVATING PROTEIN; NUCLEOTIDE BINDING; POTENTIAL BINDING; PROTEIN BINDING; PROTEIN-BINDING SITES; TWO-HYBRID SCREENS;

BIOCHEMISTRY; PEPTIDES;

NUCLEOTIDES;

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR 1; ARF GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN 1; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; NUCLEOTIDE; PROTEIN CDC42; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ALLOSTERISM; AMINO ACID COMPOSITION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; G PROTEIN LIKE DOMAIN; GENE ACTIVITY; GENE DELETION; GENE INTERACTION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; TWO HYBRID SYSTEM;

ALLOSTERIC REGULATION; ANIMALS; CDC42 GTP-BINDING PROTEIN; GTP-BINDING PROTEINS; GTPASE-ACTIVATING PROTEINS; HELA CELLS; HUMANS; MICE; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RHO GTP-BINDING PROTEINS; RHOA GTP-BINDING PROTEIN;

EID: 84861218647     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.334458     Document Type: Article

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