Inhibition of RhoA pathway rescues the endocytosis defects in Oligophrenin1 mouse model of mental retardation

Human Molecular Genetics

Volumn 18, Issue 14, 2009, Pages 2575-2583

  Khelfaoui, Malik ^a,b   Pavlowsky, Alice ^a,b   Powell, Andrew D ^c   Valnegri, Pamela ^c   Cheong, Kenneth W ^c   Blandin, Yann ^a,b   Passafaro, Maria ^d   Jefferys, John G R ^c   Chelly, Jamel ^a,b   Billuart, Pierre ^a,b  

^a INSTITUT COCHIN   (France)

^b INSERM   (France)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^d CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ACTIN BINDING PROTEIN; ADAPTOR PROTEIN; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPHIPHYSIN; CLATHRIN; ENDOPHILIN; OLIGOPHRENIN 1; PROTEIN CIN85; PROTEIN SH3; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENDOCYTOSIS; ENZYME INHIBITION; GENE DISRUPTION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE MUTATION; GENE REPRESSION; HIPPOCAMPUS; INTERNALIZATION; MENTAL DEFICIENCY; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PATHOPHYSIOLOGY; POSTSYNAPTIC INHIBITION; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; SYNAPSE VESICLE; UPREGULATION;

ANIMALS; CYTOSKELETAL PROTEINS; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ENDOCYTOSIS; GTPASE-ACTIVATING PROTEINS; HUMANS; MENTAL RETARDATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION;

MUS;

EID: 67649859657     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddp189     Document Type: Article

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